Restraint stress induces and exacerbates intestinal inflammation in interleukin-10 deficient mice.

abstract：AIM:To investigate the expression of hypoxia-inducible factor (HIF)-2alpha/endothelial PAS domain protein1 (EPAS1) in hepatocellular carcinoma (HCC). METHODS:Expression of HIF-2alpha/EPAS1 was investigated immunohistochemically on paraffin-embedded sections from 97 patients with HCC. To further confirm that HIF-2alpha...

journal_title：World journal of gastroenterology

authors： Bangoura G,Yang LY,Huang GW,Wang W

更新日期：2004-02-15 00:00:00

abstract：AIM:To assess the risk factors and the efficacy of medications of patients with gastric and duodenal ulcers among Chinese patients in Taiwan. METHODS:Patients with peptic ulcers, diagnosed by upper endoscopy, were retrospectively collected between January 2008 and December 2008. The differences were compared. RESULTS...

journal_title：World journal of gastroenterology

authors： Lee SW,Chang CS,Lee TY,Yeh HZ,Tung CF,Peng YC

更新日期：2010-04-28 00:00:00

abstract：:Cholelithiasis occurs infrequently in the paediatric age group. Hereditary spherocytosis, sickle cell anaemia and thalassemia are the haemolytic disorders most commonly associated with development of gall stones in paediatric age group. The question is whether an isolated episode of haemolysis can cause gallstones. ...

journal_title：World journal of gastroenterology

authors： Kejariwal D

更新日期：2006-04-14 00:00:00

abstract：:Hepatoid adenocarcinoma of the stomach (HAS) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. Here, we report on three patients with suspected gastric cancer who were referred to our hospital. Gastrointestinal fiberscopy on the three patients revealed two l...

journal_title：World journal of gastroenterology

authors： Ye MF,Tao F,Liu F,Sun AJ

更新日期：2013-07-21 00:00:00

abstract：AIM:To investigate the association of nuclear morphometry and DNA content with resectability of pancreatic cancer. METHODS:A total of 36 patients with pancreatic adenocarcinoma were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of tumor cells were analyzed by IBAS autoi...

journal_title：World journal of gastroenterology

authors： He YC,Peng W,Qiao JG,Cao J,Chen JW

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Accumulating evidence has revealed that several long non-coding ribonucleic acids (lncRNAs) are crucial in the progress of hepatocellular carcinoma (HCC). AIM:To classify a long non-coding RNA, i.e., lncRNA W5, and to determine the clinical significance and potential roles of lncRNA W5 in HCC. METHODS:The ...

journal_title：World journal of gastroenterology

authors： Lei GL,Fan HX,Wang C,Niu Y,Li TL,Yu LX,Hong ZX,Yan J,Wang XL,Zhang SG,Ren MJ,Yang PH

更新日期：2021-01-07 00:00:00

abstract：AIM:To investigate the pharmacological effect of TongXie-YaoFang (TXYF) formula, a Chinese herbal formula, on Diarrhea-predominant irritable bowel syndrome (D-IBS) rats. METHODS:In a neonatal maternal separation plus restraint stress (NMS + RS) model of D-IBS, male Sprague Dawley rats were randomly divided into two gr...

journal_title：World journal of gastroenterology

authors： Yang C,Xiong Y,Zhang SS,An FM,Sun J,Zhang QL,Zhan Q

更新日期：2016-12-28 00:00:00

abstract：AIM:To investigate the dynamic features of insulin-like growth factor-I receptor (IGF-IR) expression in rat hepatocarcinogenesis, and the relationship between IGF-IR and hepatocytes malignant transformation at mRNA or protein level. METHODS:Hepatoma models were made by inducing with 2-fluorenylacetamide (2-FAA) on mal...

journal_title：World journal of gastroenterology

authors： Yan XD,Yao M,Wang L,Zhang HJ,Yan MJ,Gu X,Shi Y,Chen J,Dong ZZ,Yao DF

更新日期：2013-09-28 00:00:00

abstract：AIM:To evaluate the diagnostic value of gadobenate dimeglumine (Gd-BOPTA)-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in evaluating hepatic fibrosis and hepatitis. METHODS:Hepatocyte-phase images of Gd-BOPTA-enhanced MRI were retrospectively evaluated in 76 patients with chronic liver disease. These pat...

journal_title：World journal of gastroenterology

authors： Li XM,Chen Z,Xiao EH,Shang QL,Ma C

更新日期：2017-05-07 00:00:00

abstract：:Helicobacter pylori (H. pylori) infects more than half of the world's human population, but only 1% to 3% of infected people consequently develop gastric adenocarcinomas. The clinical outcome of the infection is determined by host genetic predisposition, bacterial virulence factors, and environmental factors. The asso...

journal_title：World journal of gastroenterology

authors： Hagymási K,Tulassay Z

更新日期：2014-06-07 00:00:00

abstract：:Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-densit...

journal_title：World journal of gastroenterology

authors： Temel RE,Brown JM

更新日期：2010-12-21 00:00:00

abstract：:Significant disparities exist between genders for the development and progression of several gastro-intestinal (GI) diseases including cancer. Differences in incidence between men vs women for colon, gastric and hepatocellular cancers suggest a role for steroid sex hormones in regulation of GI carcinogenesis. Involvem...

journal_title：World journal of gastroenterology

authors： Sukocheva OA,Li B,Due SL,Hussey DJ,Watson DI

更新日期：2015-05-28 00:00:00

abstract：AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

journal_title：World journal of gastroenterology

authors： Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

更新日期：2017-08-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：AIM:To evaluate the impact of glycemic control and nutritional status after total pancreatectomy (TP) on complications, tumor recurrence and overall survival. METHODS:Retrospective records of 52 patients with pancreatic tumors who underwent TP were collected from 2007 to 2015. A series of clinical parameters collected...

journal_title：World journal of gastroenterology

authors： Shi HJ,Jin C,Fu DL

更新日期：2017-01-14 00:00:00

abstract：AIM:To investigate the role of enhancer of zeste homologue 2 (EZH2) and STAT6 immunohistochemistry in the evaluation of clinical stages and prognosis of colorectal cancer (CRC). METHODS:The expression patterns were examined by immunohistochemistry in both tumor and adjacent non-neoplastic tissues of 119 CRC patients w...

journal_title：World journal of gastroenterology

authors： Wang CG,Ye YJ,Yuan J,Liu FF,Zhang H,Wang S

更新日期：2010-05-21 00:00:00

abstract：AIM:Recent reports have shown the capacity of mesenchymal stem cells (MSCs) to differentiate into hepatocytes in vitro and in vivo. MSCs administration could repair injured liver, lung, or heart through reducing inflammation, collagen deposition, and remodeling. These results provide a clue to treatment of liver fibros...

journal_title：World journal of gastroenterology

authors： Zhao DC,Lei JX,Chen R,Yu WH,Zhang XM,Li SN,Xiang P

更新日期：2005-06-14 00:00:00

abstract：AIM:Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation. Ursodeoxycholic acid (UDCA) is now used as a first-line drug for asymptomatic PBC (aPBC) because it is reported that UDCA decrea...

journal_title：World journal of gastroenterology

authors： Dohmen K,Mizuta T,Nakamuta M,Shimohashi N,Ishibashi H,Yamamoto K

更新日期：2004-03-15 00:00:00

abstract：AIM:To determine the prevalence, histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population. METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between Janua...

journal_title：World journal of gastroenterology

authors： Graham RP,Williams NP,West KA

更新日期：2009-03-28 00:00:00

abstract：AIM:To determine the in vivo and in vivo effects of cysteamine (CS) on expression and activity of H(+)-K(+)-ATPase of gastric mucosal cells in weaning piglets. METHODS:Eighteen litters of newborn Xinhuai piglets were employed in the in vivo experiment and allocated to control and treatment groups. From 12 d of age (D1...

journal_title：World journal of gastroenterology

authors： Shi ZM,Du GM,Wei XH,Zhang L,Chen J,Zhao RQ

更新日期：2005-11-14 00:00:00

abstract：:Jejunoileal bypass (JIB), popular in the 1960s and 1970s, had remarkable success in achieving weight loss by creating a surgical short bowel syndrome. Our patient had an unusual case of liver disease and provided no history of prior bariatric surgery. Later, it was recognized that he had a JIB in the 1970s, which was ...

journal_title：World journal of gastroenterology

authors： Singh D,Laya AS,Clarkston WK,Allen MJ

更新日期：2009-05-14 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

journal_title：World journal of gastroenterology

authors： Lazaraki G,Chatzimavroudis G,Katsinelos P

更新日期：2014-07-21 00:00:00

abstract：:We present a female patient with continuous melena, diagnosed with rectal variceal bleeding. She had a history of esophageal varices, which were treated with endoscopic therapy. Five years after the treatment of esophageal varices, continuous melena occurred. Since colonoscopy showed that the melena was caused by gian...

journal_title：World journal of gastroenterology

authors： Okazaki H,Higuchi K,Shiba M,Nakamura S,Wada T,Yamamori K,Machida A,Kadouchi K,Tamori A,Tominaga K,Watanabe T,Fujiwara Y,Nakamura K,Arakawa T

更新日期：2006-09-07 00:00:00

abstract：:Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is frequently associated with type 1 autoimmune pancreatitis (AIP). Association with AIP can be utilized in the diagnosis of IgG4-SC. However, some cases of IgG4-SC are isolated from AIP, which complicates the diagnosis. Most of the reported cases of isolated ...

journal_title：World journal of gastroenterology

authors： Nakazawa T,Ikeda Y,Kawaguchi Y,Kitagawa H,Takada H,Takeda Y,Makino I,Makino N,Naitoh I,Tanaka A

更新日期：2015-01-28 00:00:00

abstract：:Endoscopic mucosal resection (EMR) allows the removal of flat or sessile lesions, laterally spreading tumors, and carcinoma of the colon or the rectum limited to the mucosa or the superficial submucosa. Acute appendicitis is the most common abdominal emergency requiring emergency surgery, and it is also a rare complic...

journal_title：World journal of gastroenterology

authors： Nemoto Y,Tokuhisa J,Shimada N,Gomi T,Maetani I

更新日期：2015-07-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the 10 most common cancers worldwide. There is no ideal treatment for HCC yet and many researchers are trying to improve the effects of treatment by changing therapeutic strategies. As the majority of human cancers seem to exhibit either abnormal p53 gene or disrupted p53 gene ...

journal_title：World journal of gastroenterology

authors： Guan YS,La Z,Yang L,He Q,Li P

更新日期：2007-02-21 00:00:00

abstract：AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specific to 16S rRNA of Helicobacter spp. was performed on paraffin-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The sample...

journal_title：World journal of gastroenterology

authors： Karagin PH,Stenram U,Wadström T,Ljungh A

更新日期：2010-10-14 00:00:00

abstract：AIM:To compare the efficacy of different chemotherapeutic agents during conventional transarterial chemoembolization (cTACE) in the treatment of unresectable hepatocellular carcinoma (HCC). METHODS:A retrospective review was undertaken of patients with unresectable HCC undergoing cTACE from May 2003 to November 2011. ...

journal_title：World journal of gastroenterology

authors： Wu J,Song L,Zhao DY,Guo B,Liu J

更新日期：2014-08-21 00:00:00

abstract：:Celiac disease (CD) is a permanent auto-immune enteropathy, triggered in genetically predisposed individuals by the ingestion of dietary gluten. Gluten is the alcohol-soluble protein component of the cereals wheat, rye and barley. CD is a multifactorial condition, originating from the interplay of genetic and environm...

journal_title：World journal of gastroenterology

authors： Silano M,Agostoni C,Guandalini S

更新日期：2010-04-28 00:00:00

abstract：AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

journal_title：World journal of gastroenterology

authors： Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

更新日期：2005-10-28 00:00:00