Stroke and dilated cardiomyopathy associated with celiac disease.

Abstract:

:Celiac disease (CD) is manifested by a variety of clinical signs and symptoms that may begin either in childhood or adult life. Neurological symptoms without signs of malabsorption have been observed for a long time in CD. In this report, an 8-year-old girl with CD presented with rarely seen dilated cardiomyopathy and stroke. The girl was admitted with left side weakness. Her medical history indicated abdominal distention, chronic diarrhea, failure to thrive, and geophagia. On physical examination, short stature, pale skin and a grade 2 of 6 systolic murmur were detected. Muscle strength was 0/5 on the left side, and 5/5 on the right side. Coagulation examinations were normal. Tests for collagen tissue diseases were negative. Factor V Leiden and prothrombin GA20210 mutations were negative. Tandem mass spectrophotometry and blood carnitine profiles were normal. Brain magnetic resonance imaging and cerebral angiography showed an infarction area at the basal ganglia level. Examinations of serologic markers and intestinal biopsy revealed CD. We emphasize that in differential diagnosis of ischemic stroke, CD should be kept in mind.

journal_name

World J Gastroenterol

authors

Doğan M,Peker E,Cagan E,Akbayram S,Acikgoz M,Caksen H,Uner A,Cesur Y

doi

10.3748/wjg.v16.i18.2302

subject

Has Abstract

pub_date

2010-05-14 00:00:00

pages

2302-4

issue

18

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

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