Abstract：
AIM:To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease (IBD). METHODS:Patients with ulcerative colitis (UC) or Crohn's disease (CD) related diagnostic codes who received medical care at University of Mississippi Medical Center between July 2012 and 2015 were identified. After thorough chart review, we identified patients with biopsy proven IBD who had also been tested for serum 25-hydroxyvitamin D [25(OH)D] concentration. We compared these patients to a previously studied cohort of healthy controls who also had vitamin D concentration checked. Logistic regression analysis was performed to determine the association between vitamin d deficiency and UC, CD, race, age, gender and body mass index (BMI). RESULTS:We identified 237 patients with confirmed IBD. Of these, only 211 had a serum 25(OH)D concentrations available in the medical record. The group of healthy controls consisted of 98 individuals with available serum 25(OH)D concentration. 43% of IBD patients were African American (AA). Patients with CD were more likely to have vitamin D concentration checked. Bivariate analysis showed that AA (51% vs 21%, P = 0.00001), subjects with BMI >30 kg/m2 (39% vs 23% P = 0.01) and CD (40% vs 26%, P = 0.04) were more likely to be vitamin D deficient than vitamin D sufficient. Those with Age > 65 were more likely to be vitamin D sufficient (46% vs 15%, P = 0.04). Multiple regression showed that only BMI > 30 kg/m2 and AA race are associated with vitamin D deficiency. CONCLUSION:BMI > 30 kg/m2 and AA race are predictive of vitamin D deficiency. Gender, age and diagnosis of IBD are not predictive of vitamin D deficiency.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Pallav K,Riche D,May WL,Sanchez P,Gupta NKdoi
10.3748/wjg.v23.i4.638subject
Has Abstractpub_date
2017-01-28 00:00:00pages
638-645issue
4eissn
1007-9327issn
2219-2840journal_volume
23pub_type
杂志文章abstract：AIM:To prepare the human hepatocellular carcinoma-(HCC)-targeted liposome microbubbles and to investigate their immunological properties. METHODS:Human hepatocarcinoma specific monoclonal antibody HAb18 was attached to the surface of home-made liposome microbubbles by static attraction to prepare the targeted liposome...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
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journal_title：World journal of gastroenterology
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更新日期：2002-10-01 00:00:00
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journal_title：World journal of gastroenterology
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journal_title：World journal of gastroenterology
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更新日期：2012-03-28 00:00:00
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journal_title：World journal of gastroenterology
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doi：10.3748/wjg.v12.i3.408
更新日期：2006-01-21 00:00:00
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journal_title：World journal of gastroenterology
pub_type： 杂志文章
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更新日期：2011-10-28 00:00:00
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journal_title：World journal of gastroenterology
pub_type： 杂志文章
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更新日期：1998-04-01 00:00:00
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journal_title：World journal of gastroenterology
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journal_title：World journal of gastroenterology
pub_type： 杂志文章,多中心研究
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更新日期：2008-01-07 00:00:00
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journal_title：World journal of gastroenterology
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更新日期：2009-07-21 00:00:00
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journal_title：World journal of gastroenterology
pub_type： 杂志文章,meta分析,评审
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更新日期：2014-12-14 00:00:00
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journal_title：World journal of gastroenterology
pub_type： 杂志文章
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更新日期：2015-10-28 00:00:00
abstract：AIM:To determine the pattern and distribution of colonic diverticulosis in Thai adults. METHODS:A review of the computerized radiology database for double contrast barium enema (DCBE) in Thai adults was performed at the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Incomplete studies and...
journal_title：World journal of gastroenterology
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更新日期：2013-12-14 00:00:00
