Molecular mechanism of immune response induced by foreign plasmid DNA after oral administration in mice.

abstract：AIM:To determine the resistance patterns of Helicobacter pylori (H. pylori) strains isolated from patients in Beijing and monitor the change of antibiotic resistance over time. METHODS:In this prospective, serial and cross-sectional study, H. pylori cultures were successfully obtained from 371 and 950 patients (never ...

journal_title：World journal of gastroenterology

authors： Zhang YX,Zhou LY,Song ZQ,Zhang JZ,He LH,Ding Y

更新日期：2015-03-07 00:00:00

abstract：AIM:To identify the subset of patients with stage IB gastric cancer with an unfavorable prognosis. METHODS:Overall survival (OS) rates were examined in 103 patients with stage IB (T1N1M0 and T2N0M0) gastric cancer between January 2000 and December 2011. Univariate and multivariate analyses were performed to identify r...

journal_title：World journal of gastroenterology

authors： Aoyama T,Yoshikawa T,Fujikawa H,Hayashi T,Ogata T,Cho H,Yamada T,Hasegawa S,Tsuchida K,Yukawa N,Oshima T,Oba MS,Morita S,Rino Y,Masuda M

更新日期：2014-06-07 00:00:00

abstract：AIM:To study the effect of progesterone on contractile activity of isolated gastric strips in rats. METHODS:Wistar rats were sacrificed to remove whole stomach. Then, the stomach was opened and the mucosal layer was removed. Parallel to either the circular or the longitudinal fibers, muscle strips were cut from fundus...

journal_title：World journal of gastroenterology

authors： Wang F,Zheng TZ,Li W,Qu SY,He DY

更新日期：2003-04-01 00:00:00

abstract：:Two major types of cancer occur in the esophagus: squamous cell carcinoma, which is associated with chronic smoking and alcohol consumption, and adenocarcinoma, which typically arises in gastric reflux-associated Barrett's esophagus. Although there is increasing incidence of esophageal adenocarcinoma in Western counti...

journal_title：World journal of gastroenterology

authors： Sasaki Y,Tamura M,Koyama R,Nakagaki T,Adachi Y,Tokino T

更新日期：2016-02-21 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：:As among persons with normal anatomy, occasional patients with situs inversus develop malignant tumors. Recently, several laparoscopic operations have been reported in patients with situs inversus. We describe laparoscopic hemicolectomy with radical lymphadenectomy in such a patient. Careful consideration of the mirro...

journal_title：World journal of gastroenterology

authors： Fujiwara Y,Fukunaga Y,Higashino M,Tanimura S,Takemura M,Tanaka Y,Osugi H

更新日期：2007-10-07 00:00:00

abstract：AIM:We aimed to observe the expression of extracellular matrix (ECM) and cellular adhesion molecules (CAM) in cirrhotic liver tissues after hepatitis C virus (HCV) infection. METHODS:Twelve patients with post HCV inflammatory liver cirrhosis were selected to evaluate their liver function and other virological, patholo...

journal_title：World journal of gastroenterology

authors： Xu X,Li YM,Ji H,Hou CZ,Cheng YB,Ma FP

更新日期：2005-04-14 00:00:00

abstract：AIM:To investigate whether α-fetoprotein (AFP) and vascular endothelial growth factor receptor (VEGFR)-1 correlate with early recurrence of hepatoma/hepatocellular carcinoma (HCC). METHODS:From 2000 to 2005, 114 consecutive patients with HCC underwent primary curative hepatectomy. The mean age was 60.7 (8.7) years and...

journal_title：World journal of gastroenterology

authors： Kamiyama T,Takahashi M,Nakanishi K,Yokoo H,Kamachi H,Kobayashi N,Ozaki M,Todo S

更新日期：2012-01-28 00:00:00

abstract：AIM:To evaluate the detection and differentiation ability of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in hepatocellular carcinoma (HCC) operations. METHODS:Clinical data of 50 HCC patients were retrospective analyzed. The sensitivity, specificity, false negative and false positive rates of contrast e...

journal_title：World journal of gastroenterology

authors： Wu H,Lu Q,Luo Y,He XL,Zeng Y

更新日期：2010-01-28 00:00:00

abstract：AIM:To investigate and characterise patients with chronic hepatitis C virus (HCV) infection presenting with hepatocellular carcinoma (HCC) in the absence of cirrhosis. METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified. The clinical case notes...

journal_title：World journal of gastroenterology

authors： Nash KL,Woodall T,Brown AS,Davies SE,Alexander GJ

更新日期：2010-08-28 00:00:00

abstract：AIM:To establish an ideal implantable rat liver tumor model for interventional therapy study and examine its angiographic signs and MRI, CT features before and after embolization. METHODS:Forty male Wistar rats were implanted with Walker-256 tumor in the left lateral lobe of liver. Digital subtraction angiography (DSA...

journal_title：World journal of gastroenterology

authors： Li X,Zheng CS,Feng GS,Zhuo CK,Zhao JG,Liu X

更新日期：2002-12-01 00:00:00

abstract：AIM:To clarify the relationship between circumferential resection margin status and local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma. The relationship between circumferential resection margin status and clinicopathologic characteristics of middle and lower rectal carci...

journal_title：World journal of gastroenterology

authors： Wu ZY,Wan J,Li JH,Zhao G,Peng L,Yao Y,Du JL,Liu QF,Wang ZD,Huang ZM,Lin HH

更新日期：2007-06-28 00:00:00

abstract：:The gut-brain axis is a bidirectional information interaction system between the central nervous system (CNS) and the gastrointestinal tract, in which gut microbiota plays a key role. The gut microbiota forms a complex network with the enteric nervous system, the autonomic nervous system, and the neuroendocrine and ne...

journal_title：World journal of gastroenterology

authors： Ding JH,Jin Z,Yang XX,Lou J,Shan WX,Hu YX,Du Q,Liao QS,Xie R,Xu JY

更新日期：2020-10-28 00:00:00

abstract：AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

journal_title：World journal of gastroenterology

authors： Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

更新日期：2019-01-07 00:00:00

abstract：AIM:To investigate the effect of Boschniakia rossica (BR), oxymatrine (OM) and interferon-alpha (IFN-alpha) 1b on the therapy of rat liver fibrosis and its mechanism. METHODS:By establishing a rat model of pig serum-induced liver fibrosis, liver/weight index and serum alanine transaminase (ALT) were observed to invest...

journal_title：World journal of gastroenterology

authors： Wu CS,Piao XX,Piao DM,Jin YR,Li CH

更新日期：2005-01-07 00:00:00

abstract：AIM:Non-bioartificial liver has been applied to clinic for quite a long time, but the reported efficacy has been very different. The aim of this study was to compare the efficacy and safety of hemoperfusion adsorption, plasma exchange and plasma exchange plus hemoperfusion adsorption in treatment of severe viral hepati...

journal_title：World journal of gastroenterology

authors： He NH,Wang YJ,Wang ZW,Liu J,Li JJ,Liu GD,Wang YM

更新日期：2004-04-15 00:00:00

abstract：:Portal hypertension, one of the vascular diseases, not only has lesions in liver, but also changes in vascular structures and functions of extrahepatic portal system, systemic system and pulmonary circulation. The pathological changes of vasculopathy in portal hypertension include remodeling of arterialized visceral v...

journal_title：World journal of gastroenterology

authors： Li T,Yang Z

更新日期：2005-10-21 00:00:00

abstract：:Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and eve...

journal_title：World journal of gastroenterology

authors： Pimenta AP,Preto JR,Gouveia AM,Fonseca E,Pimenta MM

更新日期：2007-12-07 00:00:00

abstract：AIM:To investigate the effect of a single amino acid mutation in human class B scavenger receptor I (SR-BI) on the infectivity of cell culture-derived hepatitis C virus (HCVcc) in SR-BI knock-down Huh7-siSR-BI cells. METHODS:Site-directed mutagenesis was used to construct the SR-BI S112F mutation, and the mutation was...

journal_title：World journal of gastroenterology

authors： Gao R,Gao W,Xu G,Xu J,Ren H

更新日期：2017-07-28 00:00:00

abstract：AIM:To evaluate the influence of multiple samplings during esophagogastroduodenoscopy (EGD) on the accuracy of the rapid urease test, and the validity of newly developed rapid urease tests, HelicotecUT plus test and HelicotecUT test, CLO test and ProntoDry test. METHODS:A total of 355 patients undergoing EGD for dyspe...

journal_title：World journal of gastroenterology

authors： Hsu WH,Wang SS,Kuo CH,Chen CY,Chang CW,Hu HM,Wang JY,Yang YC,Lin YC,Wang WM,Wu DC,Wu MT,Kuo FC

更新日期：2010-06-21 00:00:00

abstract：AIM:To study the effect of sulfated cholecystokinin-octapeptide (CCK-8) on systemic hypotension, gene and protein expression of TNF-alpha in the spleen of lipopolysaccharide (LPS)-induced endotoxic shock (ES) rats, and further investigate the signal transduction mechanism of p38 mitogen-activated protein kinase (MAPK)....

journal_title：World journal of gastroenterology

authors： Meng AH,Ling YL,Zhang XP,Zhao XY,Zhang JL

更新日期：2002-02-01 00:00:00

abstract：AIM:To clone and express the antigen of monoclonal antibody (MAb) PD4 for further investigation of its function. METHODS:MGC803 cDNA expression library was constructed and screened with PD4 as probes to clone the antigen. After failed in the library screening, immunoprecipitation and SDS-polyacrylamide gel electrophor...

journal_title：World journal of gastroenterology

authors： Ning JY,Sun GX,Huang S,Ma H,An P,Meng L,Song SM,Wu J,Shou CC

更新日期：2003-10-01 00:00:00

abstract：:Intrahepatic clear cell cholangiocarcinoma is very rare - only 8 cases have been reported. A 56-year-old Japanese man with chronic hepatitis B infection was diagnosed with a 2.2 cm hepatocellular carcinoma on imaging, and hepatic segmentectomy was performed. Histopathologically, the tumor cells had copious clear cytop...

journal_title：World journal of gastroenterology

authors： Toriyama E,Nanashima A,Hayashi H,Abe K,Kinoshita N,Yuge S,Nagayasu T,Uetani M,Hayashi T

更新日期：2010-05-28 00:00:00

abstract：AIM:To investigate whether the patatin-like phospholipase domain containing-3 gene (PNPLA3) I148M polymorphism is associated with steatosis, fibrosis stage, and cirrhosis in hereditary hemochromatosis (HH). METHODS:We studied 174 consecutive unrelated homozygous for the C282Y HFE mutation of HH (C282Y+/+ HH) patients ...

journal_title：World journal of gastroenterology

authors： Valenti L,Maggioni P,Piperno A,Rametta R,Pelucchi S,Mariani R,Dongiovanni P,Fracanzani AL,Fargion S

更新日期：2012-06-14 00:00:00

abstract：AIM:To assess the effectiveness of endoscopic full-thickness resection (EFR) and laparoscopic surgery in the treatment of gastric stromal tumors arising from the muscularis propria. METHODS:Out of 62 gastric stromal tumors arising from the muscularis propria, each > 1.5 cm in diameter, 32 were removed by EFR, and 30 w...

journal_title：World journal of gastroenterology

authors： Huang LY,Cui J,Wu CR,Zhang B,Jiang LX,Xian XS,Lin SJ,Xu N,Cao XL,Wang ZH

更新日期：2014-07-07 00:00:00

abstract：:Inflammatory bowel disease (IBD) results from a complex series of interactions between susceptibility genes, the environment, and the immune system. Recently, some studies provided strong evidence that the process of autophagy affects several aspects of mucosal immune responses. Autophagy is a cellular stress response...

journal_title：World journal of gastroenterology

authors： Iida T,Onodera K,Nakase H

更新日期：2017-03-21 00:00:00

abstract：AIM:To study the nuclear microsatellite instability (nMSI) at BAT26 and mitochondrial microsatellite instability (mtMSI) in the occurrence and development of hepatocellular carcinoma and the relationship between nMSI and mtMSI. METHODS:nMSI was observed with PCR and mtMSI with PCR-SSCP in 52 cases of hepatocellular ca...

journal_title：World journal of gastroenterology

authors： Fang DC,Fang L,Wang RQ,Yang SM

更新日期：2004-02-01 00:00:00

abstract：AIM:To study the role of gastric mucosal ascorbic acid (AA) in the progression of acute gastric mucosal lesions induced by compound 48/80 (C48/80), a mast cell degranulator, in rats. METHODS:C48/80 (0.75 mg/kg) was intraperitoneally injected to fasted Wistar rats. Oral administration of AA (10, 50 or 100 mg/kg) was pe...

journal_title：World journal of gastroenterology

authors： Kamiya Y,Ohta Y,Imai Y,Arisawa T,Nakano H

更新日期：2005-03-07 00:00:00

abstract：:Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though only on the basis of...

journal_title：World journal of gastroenterology

authors： Fedeli U,Girardi P,Mastrangelo G

更新日期：2019-09-07 00:00:00

abstract：AIM:To investigated the effects of urotensin II (UII) on hepatic insulin resistance in HepG2 cells and the potential mechanisms involved. METHODS:Human hepatoma HepG2 cells were cultured with or without exogenous UII for 24 h, in the presence or absence of 100 nmol/L insulin for the last 30 min. Glucose levels were de...

journal_title：World journal of gastroenterology

authors： Li YY,Shi ZM,Yu XY,Feng P,Wang XJ

更新日期：2016-07-07 00:00:00