Nuclear and mitochondrial DNA microsatellite instability in hepatocellular carcinoma in Chinese.

abstract：:Cytokines are indispensable signals of the mucosa-associated immune system for maintaining normal gut homeostasis. An imbalance of their profile in favour of inflammation initiation may lead to disease states, such as that is observed in inflammatory bowel diseases (IBD). Although Crohn's disease (CD) is often describ...

journal_title：World journal of gastroenterology

authors： Műzes G,Molnár B,Tulassay Z,Sipos F

更新日期：2012-11-07 00:00:00

abstract：:We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

journal_title：World journal of gastroenterology

authors： Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

更新日期：2008-03-28 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：AIM:To construct and highly express an epitope of hepatitis C virus (HCV) in a foreign epitope presenting vector based on an insect virus, and to study the antigenicity of the epitope. METHODS:The HCV epitope sequence (amino acid residues 315 to 328: EGHRMAWDMMMNWS) of the E1 region was constructed at different positi...

journal_title：World journal of gastroenterology

authors： Peng M,Dai CB,Chen YD

更新日期：2005-06-14 00:00:00

abstract：:The diagnosis of early gastric cancer (EGC) is of great interest because its endoscopic and surgical treatment presents the best chance for a cure. With technical development, endoscopic submucosal dissection (ESD) has been widely performed for the curative treatment of EGC in Korea. Multinational studies of ESD for E...

journal_title：World journal of gastroenterology

authors： Cho WY,Cho JY,Chung IK,Kim JI,Jang JS,Kim JH

更新日期：2011-06-07 00:00:00

abstract：AIM:To observe expression of CD14 protein and CD14 gene in rat liver sinusoidal endothelial cells (LSECs) during endotoxemia, and the role of CD14 protein in the activation of lipopolysaccharide (LPS)-induced LSECs. METHODS:Wistar rat endotoxemia model was established first by injection of a dose of LPS (5mg/kg, Esche...

journal_title：World journal of gastroenterology

authors： Gong JP,Dai LL,Liu CA,Wu CX,Shi YJ,Li SW,Li XH

更新日期：2002-06-01 00:00:00

abstract：AIM:To evaluate ATP-binding cassette (ABC) transporters in colonic pathophysiology as they had recently been related to colorectal cancer (CRC) development. METHODS:Literature search was conducted on PubMed using combinations of the following terms: ABC transporters, ATP binding cassette transporter proteins, inflamma...

journal_title：World journal of gastroenterology

authors： Andersen V,Svenningsen K,Knudsen LA,Hansen AK,Holmskov U,Stensballe A,Vogel U

更新日期：2015-11-07 00:00:00

abstract：AIM:To study immune response induced by foreign plasmid DNA after oral administration in mice. METHODS:Mice were orally administered with 200 mug of plasmid pcDNA3 once and spleen was isolated 4 h and 18 h after administration. Total RNA was extracted from spleen and gene expression profile of BALB/c mice spleen was a...

journal_title：World journal of gastroenterology

authors： Liu JW,Cheng J

更新日期：2007-07-28 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：:The relationship between diabetes mellitus and the risk of pancreatic cancer has been a matter of study for a long period of time. The importance of this topic is due to two main causes: the possible use of recent onset diabetes as a marker of the disease and, in particular, as a specific marker of pancreatic cancer, ...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Pagano N

更新日期：2013-08-14 00:00:00

abstract：:A liver tumor 35 mm in diameter was found incidentally in a 40-year-old woman who had no history of liver diseases or the use of oral contraceptives. Radiological diagnostics showed the typical findings of liver cell adenoma (LCA). Dynamic computed tomography revealed that the tumor showed a homogenous enhancement in ...

journal_title：World journal of gastroenterology

authors： Kogure T,Ueno Y,Sekiguchi S,Ishida K,Igarashi T,Wakui Y,Iwasaki T,Shimosegawa T

更新日期：2009-03-14 00:00:00

abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...

journal_title：World journal of gastroenterology

authors： Lin CH,Yu JC,Chen TW,Chan DC,Chen CJ,Hsieh CB

更新日期：2005-09-14 00:00:00

abstract：:We describe herein a 68-year-old woman who was diagnosed with a quite rare entity of intraductal papillary mucinous neoplasms (IPMNs) occurring simultaneously in the left lateral lobe of liver and the tail of pancreas. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a cystic dilata...

journal_title：World journal of gastroenterology

authors： Xu XW,Li RH,Zhou W,Wang J,Zhang RC,Chen K,Mou YP

更新日期：2012-11-28 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stre...

journal_title：World journal of gastroenterology

authors： Clemente MG,Mandato C,Poeta M,Vajro P

更新日期：2016-09-28 00:00:00

abstract：:In this review, we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus (HCV) infection. Because the HCV genome is present exclusively in RNA form during replication, various nucleic acid-based therapeutic approaches targeting the HCV genome, such as ribozymes, aptamers,...

journal_title：World journal of gastroenterology

authors： Lee CH,Kim JH,Lee SW

更新日期：2013-12-21 00:00:00

abstract：AIM:To evaluate the long-term efficacy and safety of endoscopic obliteration with Histoacryl(®) for treatment of gastric variceal bleeding and prophylaxis. METHODS:Between January 1994 and March 2010 at SoonChunHyang University Hospital, a total of 127 patients with gastric varices received Histoacryl(®) injections en...

journal_title：World journal of gastroenterology

authors： Kang EJ,Jeong SW,Jang JY,Cho JY,Lee SH,Kim HG,Kim SG,Kim YS,Cheon YK,Cho YD,Kim HS,Kim BS

更新日期：2011-03-21 00:00:00

abstract：AIM:To investigate whether the simultaneous treatment with human growth hormone (hGH) abolishes the negative effects of everolimus on anastomotic healing. METHODS:Forty-eight male Sprague-Dawley-rats were randomized to three groups of 16 animals each (I: vehicle; II: everolimus 3 mg/kg po; III: everolimus 3 mg/kg po +...

journal_title：World journal of gastroenterology

authors： Küper MA,Trütschel S,Weinreich J,Königsrainer A,Beckert S

更新日期：2016-05-07 00:00:00

abstract：:Tumor immunity proceeds through multiple processes, which consist of antigen presentation by antigen presenting cells (APCs) to educate effector cells and destruction by the effector cytotoxic cells. However, tumor immunity is frequently repressed at tumor sites. Malignantly transformed cells rarely survive the attack...

journal_title：World journal of gastroenterology

authors： Mukaida N,Nakamoto Y

更新日期：2018-05-07 00:00:00

abstract：AIM:To evaluate the full-spectrum endoscopy (FUSE) colonoscopy system as the first report on the utility thereof in a Korean population. METHODS:We explored the efficacy of the FUSE colonoscopy in a retrospective, single-center feasibility study performed between February 1 and July 20, 2015. A total of 262 subjects (...

journal_title：World journal of gastroenterology

authors： Song JY,Cho YH,Kim MA,Kim JA,Lee CT,Lee MS

更新日期：2016-02-28 00:00:00

abstract：:Systemic therapy for hepatocellular carcinoma (HCC) has markedly advanced since the survival benefit of a molecular targeted agent, sorafenib, were demonstrated in the SHARP and Asia Pacific trials in 2007. Treatment options for patients with advanced HCC increased by sorafenib, and long-term survival for patients wit...

journal_title：World journal of gastroenterology

authors： Kudo M

更新日期：2019-02-21 00:00:00

abstract：AIM:To investigate the utility of K-ras mutation analysis of ultrasound guided fine-needle aspirate biopsy of pancreatic masses. METHODS:Sixty-six ultrasound guided fine-needle biopsies were evaluated by cytology, histology and k-ras mutation. The mutation at codon 12 of the k-ras oncogene was detected by artificial r...

journal_title：World journal of gastroenterology

authors： Zheng M,Liu LX,Zhu AL,Qi SY,Jiang HC,Xiao ZY

更新日期：2003-01-01 00:00:00

abstract：AIM:To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS:This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services f...

journal_title：World journal of gastroenterology

authors： Schultz M,Davidson A,Donald S,Targonska B,Turnbull A,Weggery S,Livingstone V,Dockerty JD

更新日期：2009-02-07 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：AIM:To assess the patient-reported outcomes (PROs) of pancreatic neuroendocrine tumor (PNET) patients. METHODS:Fifty-one consecutive patients (21 male, 30 female, 61.0 +/- 10.3 years) with proven PNETs were studied. An SF-12 questionnaire capable of exploring the physical (PCS) and mental (MCS) aspects of daily life w...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Campana D,Morselli-Labate AM,Fabbri MC,Brocchi E,Tomassetti P

更新日期：2009-10-28 00:00:00

abstract：:Alcohol-induced fatty liver (steatosis) was believed to result from excessive generation of reducing equivalents from ethanol metabolism, thereby enhancing fat accumulation. Recent findings have revealed a more complex picture in which ethanol oxidation is still required, but specific transcription as well as humoral ...

journal_title：World journal of gastroenterology

authors： Donohue TM Jr

更新日期：2007-10-07 00:00:00

abstract：AIM:To establish novel intestinal myofibroblast (IMF) cell lines from mouse colonic mucosa and investigate their biological characters. METHODS:Primary IMFs were isolated from mucosal tissues of mouse colon that was denuded of epithelial cells and smooth muscle layer. For immortalization, primary IMFs were transfected...

journal_title：World journal of gastroenterology

authors： Kawasaki H,Ohama T,Hori M,Sato K

更新日期：2013-05-07 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：AIM:To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS:All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS:Altogether 26 pseudocysts o...

journal_title：World journal of gastroenterology

authors： Sadik R,Kalaitzakis E,Thune A,Hansen J,Jönson C

更新日期：2011-01-28 00:00:00

abstract：AIM:To investigate possible associations of anti-nuclear envelope antibody (ANEA) with disease severity and survival in Greek primary biliary cirrhosis (PBC) patients. METHODS:Serum samples were collected at diagnosis from 147 PBC patients (85% female), who were followed-up for a median 89.5 mo (range 1-240). ANEA wer...

journal_title：World journal of gastroenterology

authors： Sfakianaki O,Koulentaki M,Tzardi M,Tsangaridou E,Theodoropoulos PA,Castanas E,Kouroumalis EA

更新日期：2010-10-21 00:00:00

abstract：:Primary liver cancer is amongst the commonest tumors worldwide, particularly in parts of the developing world, and is increasing in incidence. Over the past three decades, surgical hepatic resection has evolved from a high risk, resource intensive procedure with limited application, to a safe and commonly performed op...

journal_title：World journal of gastroenterology

authors： Tsim NC,Frampton AE,Habib NA,Jiao LR

更新日期：2010-02-28 00:00:00