E-cadherin expression pattern in primary colorectal carcinomas and their metastases reflects disease outcome.

abstract：AIM:To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS:The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface anti...

journal_title：World journal of gastroenterology

authors： Kamijo N,Matsumoto A,Umemura T,Shibata S,Ichikawa Y,Kimura T,Komatsu M,Tanaka E

更新日期：2015-01-14 00:00:00

abstract：AIM:To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS:Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorect...

journal_title：World journal of gastroenterology

authors： Mainenti PP,Iodice D,Segreto S,Storto G,Magliulo M,De Palma GD,Salvatore M,Pace L

更新日期：2011-03-21 00:00:00

abstract：:Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome is a rare genetic disorder and has not been described in China. We present a female infant with neonatal intrahepatic cholestasis from a Chinese family with ARC syndrome. All 23 coding exons and flanking introns of the VPS33B gene were amplified and sequ...

journal_title：World journal of gastroenterology

authors： Li LT,Zhao J,Chen R,Wang JS

更新日期：2014-01-07 00:00:00

abstract：AIM:To evaluate the efficacy of amantadine plus interferon-alpha and ribavirin in non-responder patients with chronic hepatitis C. METHODS:Twenty-six non-responder patients received the regimen of IFN-alpha-2a at a dose of 6 million units three times a week, 1 000-1 200 mg of ribavirin daily, and 200 mg of amantadine ...

journal_title：World journal of gastroenterology

authors： Oguz D,Cicek B,Filik L,Odemis B,Kilic M,Altintas E,Zengin N,Altiparmak E

更新日期：2005-01-28 00:00:00

abstract：BACKGROUND:The Korea National Cancer Screening Program currently provides screening for colorectal cancer (CRC) for adults older than 50 years with no upper age limit. In general, people are likely to only pay attention to the benefits of cancer screening and to neglect its risks. Most consider the benefits of cancer s...

journal_title：World journal of gastroenterology

authors： Luu XQ,Lee K,Lee YY,Suh M,Kim Y,Choi KS

更新日期：2020-07-21 00:00:00

abstract：AIM:To evaluate the effects of betaine on the ethanol-induced secretion of IGF-I and IGFBP-1 using radioimmunoassay and Western blotting, respectively, in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of ethanol and PD98059 proce...

journal_title：World journal of gastroenterology

authors： Lee MS,Kim MS,Park SY,Kang CW

更新日期：2006-03-21 00:00:00

abstract：:The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the specific biological features of these neoplasms led to the development of new targeted therapies, which take the abundan...

journal_title：World journal of gastroenterology

authors： Hopfner M,Schuppan D,Scherubl H

更新日期：2008-12-14 00:00:00

abstract：:A 91-year-old man was referred to our hospital with intermittent dysphagia. He had undergone esophagectomy for esophageal cancer (T3N2M0 Stage III) 11 years earlier. Endoscopic examination revealed an anastomotic stricture; signs of inflammation, including redness, erosion, edema, bleeding, friability, and exudate wit...

journal_title：World journal of gastroenterology

authors： Takeshita N,Kanda N,Fukunaga T,Kimura M,Sugamoto Y,Tasaki K,Uesato M,Sazuka T,Maruyama T,Aida N,Tamachi T,Hosokawa T,Asai Y,Matsubara H

更新日期：2015-08-14 00:00:00

abstract：:Folate deficiency and its association with cancer have been studied in the literature, but its clinical impact is still unknown. Folate deficiency and its result on gastric cancer is a mysterious part of oncology, with ongoing studies hopefully clarifying its impact on gastric cancer management. Lee et al studied fola...

journal_title：World journal of gastroenterology

authors： Alkan A,Mızrak D,Utkan G

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate the prognostic significance of perioperative leukopenia in patients with resected gastric cancer. METHODS:A total of 614 eligible gastric cancer patients who underwent curative D2 gastrectomy and adjuvant chemotherapy were enrolled in this study. The relationship between pre- and postoperative hemat...

journal_title：World journal of gastroenterology

authors： Chen XF,Qian J,Pei D,Zhou C,Røe OD,Zhu F,He SH,Qian YY,Zhou Y,Xu J,Xu J,Li X,Ping GQ,Liu YQ,Wang P,Guo RH,Shu YQ

更新日期：2016-03-07 00:00:00

abstract：AIM:To investigate the mechanisms of aspirin increasing the susceptibility of Helicobacter pylori (H pylori) to metronidazole. METHODS:H pylori reference strain 26695 and two metronidazole-resistant isolates of H pylori were included in this study. Strains were incubated in Brucella broth with or without aspirin (1 mm...

journal_title：World journal of gastroenterology

authors： Zhang XP,Wang WH,Tian Y,Gao W,Li J

更新日期：2009-02-28 00:00:00

abstract：AIM:To characterize the expression and dynamic changes of bone morphogenetic protein (BMP)-2 in hepatocytes in the regenerating liver in rats after partial hepatectomy (PH), and examine the effects of BMP-2 on proliferation of human Huh7 hepatoma cells. METHODS:Fifty-four adult male Wistar rats were randomly divided i...

journal_title：World journal of gastroenterology

authors： Xu CP,Ji WM,van den Brink GR,Peppelenbosch MP

更新日期：2006-12-21 00:00:00

abstract：AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

journal_title：World journal of gastroenterology

authors： Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

更新日期：2006-04-21 00:00:00

abstract：AIM:To evaluate the clinical advantages of single-port laparoscopic hepatectomy (SPLH) compare to multi-port laparoscopic hepatectomy (MPLH). METHODS:We retrospectively reviewed the medical records of 246 patients who underwent laparoscopic liver resection between January 2008 and December 2015 at our hospital. We div...

journal_title：World journal of gastroenterology

authors： Han JH,You YK,Choi HJ,Hong TH,Kim DG

更新日期：2018-01-21 00:00:00

abstract：AIM:Non-bioartificial liver has been applied to clinic for quite a long time, but the reported efficacy has been very different. The aim of this study was to compare the efficacy and safety of hemoperfusion adsorption, plasma exchange and plasma exchange plus hemoperfusion adsorption in treatment of severe viral hepati...

journal_title：World journal of gastroenterology

authors： He NH,Wang YJ,Wang ZW,Liu J,Li JJ,Liu GD,Wang YM

更新日期：2004-04-15 00:00:00

abstract：AIM:To detect the expression of mitochondrial uncoupling protein 2 (UCP2) in colon cancer and analyze the relation between UCP2 expression and clinical pathological features of colon cancer. METHODS:Fifteen colon tissue samples and 15 its adjacent tissue samples were obtained from colon cancer patients during surgical...

journal_title：World journal of gastroenterology

authors： Kuai XY,Ji ZY,Zhang HJ

更新日期：2010-12-07 00:00:00

abstract：AIM:To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia. METHODS:We genotyped 355 Estonians by polymerase chain reaction and direct sequencing. Milk consumption was analyzed by a que...

journal_title：World journal of gastroenterology

authors： Lember M,Torniainen S,Kull M,Kallikorm R,Saadla P,Rajasalu T,Komu H,Järvelä I

更新日期：2006-12-07 00:00:00

abstract：AIM:gamma-glutamyl transpeptidase (GGT) has been reported as a virulence and colonizing factor of Helicobacter pylori (H pylori). This study examined the effect of GGT on the growth of H pylori. METHODS:Standard H pylori strain NCTC 11637 and 4 clinical isolates with different levels of GGT activity as measured by an ...

journal_title：World journal of gastroenterology

authors： Gong M,Ho B

更新日期：2004-10-15 00:00:00

abstract：AIM:To determine the prevalence, histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population. METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between Janua...

journal_title：World journal of gastroenterology

authors： Graham RP,Williams NP,West KA

更新日期：2009-03-28 00:00:00

abstract：:Hepatitis C virus (HCV) infection induces steatosis and is accompanied by multiple metabolic alterations including hyperuricemia, reversible hypocholesterolemia and insulin resistance. Total cholesterol, low-density lipoprotein-cholesterol and triglyceride levels are increased by peginterferon and ribavirin combinatio...

journal_title：World journal of gastroenterology

authors： Kanda T,Moriyama M

更新日期：2017-08-21 00:00:00

abstract：AIM:Clinical and experimental data suggest that gut-derived endotoxins are an important pathogenic factors for progression of chronic liver disease. Recently, a C-T (-159) polymorphism in the promoter region of the CD14 gene was detected and found to confer increased CD14 expression and to be associated with advanced a...

journal_title：World journal of gastroenterology

authors： Meiler C,Muhlbauer M,Johann M,Hartmann A,Schnabl B,Wodarz N,Schmitz G,Scholmerich J,Hellerbrand C

更新日期：2005-10-14 00:00:00

abstract：:Wireless capsule endoscope (WCE) for the investigation of the small bowel is an approved technique both in adults and children (more than 10 years old). The present review provides data on the indications, diagnostic yield, adverse events and limitations of the WCE technique in children and tries to predict the future...

journal_title：World journal of gastroenterology

authors： Shamir R,Eliakim R

更新日期：2008-07-14 00:00:00

abstract：:Primary hepatic neuroendocrine carcinoma (NEC) with concurrent occurrence of hepatocellular carcinoma (HCC) of the liver is very rare. Only 8 cases have been reported in the literature. Concurrent occurrence of HCC and NEC in the liver is classified as combined type or collision type by histological distributional pat...

journal_title：World journal of gastroenterology

authors： Choi GH,Ann SY,Lee SI,Kim SB,Song IH

更新日期：2016-11-07 00:00:00

abstract：AIM:It has been noticed that gastroenteritis or dysentery plays a role in pathogenesis of irritable bowel syndrome (IBS), and antibiotics can increase functional abdominal symptoms, both of which may be partly due to intestinal flora disorders. This study was to determine the change of gut flora of IBS, a cluster of ab...

journal_title：World journal of gastroenterology

authors： Si JM,Yu YC,Fan YJ,Chen SJ

更新日期：2004-06-15 00:00:00

abstract：:Celiac disease (CD) is manifested by a variety of clinical signs and symptoms that may begin either in childhood or adult life. Neurological symptoms without signs of malabsorption have been observed for a long time in CD. In this report, an 8-year-old girl with CD presented with rarely seen dilated cardiomyopathy and...

journal_title：World journal of gastroenterology

authors： Doğan M,Peker E,Cagan E,Akbayram S,Acikgoz M,Caksen H,Uner A,Cesur Y

更新日期：2010-05-14 00:00:00

abstract：AIM:A single-chain antibody fragment, ND-1scFv, against human colorectal carcinoma was constructed and expressed in E.coli, and its biodistribution and pharmacokinetic properties were studied in mice bearing tumor. METHODS:V(H) and V(L) genes were amplified from hybridoma cell IC-2, secreting monoclonal antibody ND-1,...

journal_title：World journal of gastroenterology

authors： Fang J,Jin HB,Song JD

更新日期：2003-04-01 00:00:00

abstract：:Gastrointestinal cancers represent a major cause of morbidity and mortality, with incomplete response to chemotherapy in the advanced stages and poor prognosis. Angiogenesis plays a crucial part in tumor growth and metastasis, with most gastrointestinal cancers depending strictly on the development of a new and devote...

journal_title：World journal of gastroenterology

authors： Gheonea DI,Cârţână T,Ciurea T,Popescu C,Bădărău A,Săftoiu A

更新日期：2011-01-07 00:00:00

abstract：AIM:To study the association between exposure to Salmonella enterica (SE) and Crohn's disease (CD) and its clinical implications in Chilean patients. METHODS:Ninety-four unrelated Chilean CD patients from CAREI (Active Cohort Registry of Inflammatory Bowel Disease) presenting to a single inflammatory bowel disease (IB...

journal_title：World journal of gastroenterology

authors： Alvarez-Lobos M,Pizarro DP,Palavecino CE,Espinoza A,Sebastián VP,Alvarado JC,Ibañez P,Quintana C,Díaz O,Kalergis AM,Bueno SM

更新日期：2013-09-21 00:00:00

abstract：AIM:To investigate the pharmacological effects of rice flavone (5,4'-dihydroxy-3',5'-dimethoxy-7-O-beta-D-glucopyranosyloxy-flavone, RF) separated from panicle-differentiating to flowing rice on rat experimental hepatic injury. METHODS:Models of rat acute hepatic injury induced by carbon tetrachloride (CCl(4)) adminis...

journal_title：World journal of gastroenterology

authors： Xu DH,Mei XT,Chen Y,Li YM,Lv JY,Xu SB

更新日期：2005-03-28 00:00:00

abstract：AIM:To investigate the correlation between ezrin expression and invasive phenotype formation in malignantly transformed esophageal epithelial cells. METHODS:The experimental cell line employed in the present study was originated form the progressive induction of a human embryonic esophageal epithelial cell line (SHEE)...

journal_title：World journal of gastroenterology

authors： Shen ZY,Xu LY,Chen MH,Li EM,Li JT,Wu XY,Zeng Y

更新日期：2003-06-01 00:00:00