Effect of interferon and ribavirin combined with amantadine in interferon and ribavirin non-responder patients with chronic hepatitis C (genotype 1).

abstract：:AIM:To observe the tumor inhibitory effects by transfecting IL-6 cDNA into colon cancer cell line HT-29 with retroviral vector pZIP cDNA.METHODS:Human IL-6 gene was reconstructed in retrovirus vector and transfected into incasing cells PA317 by lipofectamine mediated method, the clones of the cells transferred with hI...

journal_title：World journal of gastroenterology

authors： Xiao B,Jing B,Zhang YL,Zhou DY,Zhang WD

更新日期：2000-02-01 00:00:00

abstract：AIM:To elucidate the relationship between apoptotic protease activating factor-1 (Apaf-1) gene and gastric cancer. METHODS:Thirty-five postoperative cancer and adjacent normal tissue samples were collected in the present study. Expression of the Apaf-1 gene in these samples was analyzed by semi-quantitative RT-PCR. Lo...

journal_title：World journal of gastroenterology

authors： Wang HL,Bai H,Li Y,Sun J,Wang XQ

更新日期：2007-10-14 00:00:00

abstract：:Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been compli...

journal_title：World journal of gastroenterology

authors： Shen YZ,Wang ZY,Lu HZ

更新日期：2012-10-07 00:00:00

abstract：BACKGROUND:Serum amyloid A (SAA) is an acute phase protein mainly synthesized by the liver. SAA induces inflammatory phenotype and promotes cell proliferation in activated hepatic stellate cells, the major scar forming cells in the liver. However, few studies have reported on the serum levels of SAA in human liver dise...

journal_title：World journal of gastroenterology

authors： Yuan ZY,Zhang XX,Wu YJ,Zeng ZP,She WM,Chen SY,Zhang YQ,Guo JS

更新日期：2019-11-21 00:00:00

abstract：AIM:To investigate urotensin-II (UII) and its effects on tumor necrosis factor (TNF)-α and interleukin (IL)-1β in early acute liver failure (ALF). METHODS:We investigated the time-dependent alteration in UII levels and its effects on TNF-α and IL-1β in liver and blood in the early stage of lipopolysaccharide/D-galacto...

journal_title：World journal of gastroenterology

authors： Liu LM,Zhao L,Liang DY,Yu FP,Ye CG,Tu WJ,Zhu T

更新日期：2015-03-21 00:00:00

abstract：AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP). METHODS:We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery...

journal_title：World journal of gastroenterology

authors： Katsinelos P,Kountouras J,Chatzimavroudis G,Zavos C,Pilpilidis I,Fasoulas K,Paroutoglou G

更新日期：2009-12-28 00:00:00

abstract：:The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely betwee...

journal_title：World journal of gastroenterology

authors： Hov JR,Boberg KM,Karlsen TH

更新日期：2008-06-28 00:00:00

abstract：AIM:To investigate oxaliplatin-induced severe anaphylactic reactions (SAR) in metastatic colorectal cancer in a retrospective case series analysis and to conduct a systemic literature review. METHODS:During a 6-year period from 2006 to 2011 at Kaohsiung Veterans General Hospital, a total of 412 patients exposed to oxa...

journal_title：World journal of gastroenterology

authors： Wang JH,King TM,Chang MC,Hsu CW

更新日期：2012-10-14 00:00:00

abstract：AIM:To investigate the effect of integrin-linked kinase (ILK) on proliferation, metastasis, and invasion of the colorectal cancer cell line SW480. METHODS:In this study, the colorectal cancer cell line SW480 was stably transfected with ILK plasmids, and small interfering RNA (siRNA) was used to knockdown expression of...

journal_title：World journal of gastroenterology

authors： Shen H,Ma JL,Zhang Y,Deng GL,Qu YL,Wu XL,He JX,Zhang S,Zeng S

更新日期：2016-04-21 00:00:00

abstract：:In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

journal_title：World journal of gastroenterology

authors： Cui S,Chang PY

更新日期：2016-08-21 00:00:00

abstract：AIM:To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS:Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorect...

journal_title：World journal of gastroenterology

authors： Mainenti PP,Iodice D,Segreto S,Storto G,Magliulo M,De Palma GD,Salvatore M,Pace L

更新日期：2011-03-21 00:00:00

abstract：:The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently been approved for this disease, response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment ...

journal_title：World journal of gastroenterology

authors： Wich C,Agaimy A,Strobel D,Wissniowski TT,Hartmann A,Ocker M

更新日期：2010-07-28 00:00:00

abstract：:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment ...

journal_title：World journal of gastroenterology

authors： Wu CX,Zhu ZH

更新日期：2014-04-28 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...

journal_title：World journal of gastroenterology

authors： Pompili M,Biolato M,Miele L,Grieco A

更新日期：2013-11-28 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the gallbladder is a rare subtype of gallbladder tumor. Here, we report two cases of NEC in two patients initially suspected to have gallbladder carcinoma. No specific symptoms or abnormal blood test results were observed preoperatively. Abdominal computed tomography scans indicated i...

journal_title：World journal of gastroenterology

authors： Chen H,Shen YY,Ni XZ

更新日期：2014-09-07 00:00:00

abstract：AIM:Single nucleotide polymorphisms (SNPs) of uridine-diphosphoglucuro-nosyltransferase 1A7 (UGT1A7) gene are associated with the development of orolaryngeal cancer, hepatocellular carcinoma, and colorectal cancer. We performed this research to establish the techniques for determining UGT1A7 gene and basic data of this...

journal_title：World journal of gastroenterology

authors： Huang MJ,Yang SS,Lin MS,Huang CS

更新日期：2005-02-14 00:00:00

abstract：AIM:To determine whether efflux systems contribute to multidrug resistance of H pylori. METHODS:A chloramphenicol-induced multidrug resistance model of six susceptible H pylori strains (5 isolates and H pylori NCTC11637) was developed. Multidrug-resistant (MDR) strains were selected and the minimal inhibitory concentr...

journal_title：World journal of gastroenterology

authors： Liu ZQ,Zheng PY,Yang PC

更新日期：2008-09-07 00:00:00

abstract：:AIM:To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine Qing Yi Tang in acute necrotizing pancreatitis (ANP).METHODS:After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medi...

journal_title：World journal of gastroenterology

authors： Li ZL,Wu CT,Lu LR,Zhu XF,Xiong DX

更新日期：1998-08-01 00:00:00

abstract：AIM:To investigate the safety and efficacy of a Hansenula-derived PEGylated (polyethylene glycol) interferon (IFN)-alpha-2a (Reiferon Retard) plus ribavirin customized regimen in treatment-naïve and previously treated (non-responders and relapsers) Egyptian children with chronic hepatitis C infection. METHODS:Forty-si...

journal_title：World journal of gastroenterology

authors： El Naghi S,Abdel-Ghaffar TY,El-Karaksy H,Abdel-Aty EF,El-Raziky MS,Allam AA,Helmy H,El-Araby HA,Behairy BE,El-Guindi MA,El-Sebaie H,Abdel-Ghaffar AY,Ehsan NA,El-Hennawy AM,Sira MM

更新日期：2014-04-28 00:00:00

abstract：AIM:To investigate the distribution pattern of lymphatic vessels and microvessels in sporadic colorectal carcinoma (SCRC) and their relationship to metastasis and prognosis. METHODS:The lymphatic vessel density (LVD) and microvessel density (MVD) in tumor tissue obtained from 132 patients with primary SCRC, including ...

journal_title：World journal of gastroenterology

authors： Yan G,Zhou XY,Cai SJ,Zhang GH,Peng JJ,Du X

更新日期：2008-01-07 00:00:00

abstract：:Laparoscopic gastrectomy has been widely accepted as a standard alternative for the treatment of early-stage gastric adenocarcinoma because of its favorable short-term outcomes. Although controversies exist, such as establishing clear indications, proper preoperative staging, and oncologic safety, experienced surgeons...

journal_title：World journal of gastroenterology

authors： Son T,Hyung WJ

更新日期：2016-01-14 00:00:00

abstract：AIM:To evaluate the efficacy of sequential vs hybrid therapy in patients with Helicobacter pylori (H. pylori) infection. METHODS:From March 2013 to May 2014, one hundred and seventy-five H. pylori infected patients who had not been treated for H. pylori before were randomized to receive either sequential therapy (rabe...

journal_title：World journal of gastroenterology

authors： Chen KY,Lin TJ,Lin CL,Lee HC,Wang CK,Wu DC

更新日期：2015-09-28 00:00:00

abstract：AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

journal_title：World journal of gastroenterology

authors： Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

更新日期：2008-02-28 00:00:00

abstract：:Patients with advanced gastric cancer (AGC) can be treated with multiple lines of chemotherapy. Although several randomized trials have demonstrated the benefit of second-line chemotherapy compared with best supportive care, there is no evidence that further lines of chemotherapy will result in substantial prolongatio...

journal_title：World journal of gastroenterology

authors： Kim SM,Park SH

更新日期：2015-08-07 00:00:00

abstract：AIM:To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS:We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding t...

journal_title：World journal of gastroenterology

authors： Enns RA,Gagnon YM,Barkun AN,Armstrong D,Gregor JC,Fedorak RN,RUGBE Investigators Group.

更新日期：2006-12-28 00:00:00

abstract：AIM:To cure typically life-threatening esophagogastric anastomosis in rats, lacking anastomosis healing and sphincter function rescue, in particular. METHODS:Because we assume esophagogastric fistulas represent a particular NO-system disability, we attempt to identify the benefits of anti-ulcer stable gastric pentadec...

journal_title：World journal of gastroenterology

authors： Djakovic Z,Djakovic I,Cesarec V,Madzarac G,Becejac T,Zukanovic G,Drmic D,Batelja L,Zenko Sever A,Kolenc D,Pajtak A,Knez N,Japjec M,Luetic K,Stancic-Rokotov D,Seiwerth S,Sikiric P

更新日期：2016-11-07 00:00:00

abstract：AIM:To assess the value of multidetector-row computed tomography (MDCT) in choosing retreatment methods of hepatocellular carcinoma (HCC) through evaluating the blood supply of low-density area of HCC after transcatheter arterial chemoembolization (TACE). METHODS:Thirty-two patients with HCC after TACE treatment were ...

journal_title：World journal of gastroenterology

authors： Guan YS,Zheng XH,Zhou XP,Huang J,Sun L,Chen X,Li X,He Q

更新日期：2004-07-15 00:00:00

abstract：:We report the case of a 21-year-old man who was noted to have pneumomediastinum during an admission for an acute flare of ulcerative colitis. At that time, he was on maintenance treatment with azathioprine at a dose of 1.25 mg/kg per day, and had not received supplementary steroids for 9 mo. He had never received anti...

journal_title：World journal of gastroenterology

authors： Lee JC,Bell DC,Guinness RM,Ahmad T

更新日期：2009-04-21 00:00:00

abstract：:Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome is a rare genetic disorder and has not been described in China. We present a female infant with neonatal intrahepatic cholestasis from a Chinese family with ARC syndrome. All 23 coding exons and flanking introns of the VPS33B gene were amplified and sequ...

journal_title：World journal of gastroenterology

authors： Li LT,Zhao J,Chen R,Wang JS

更新日期：2014-01-07 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known regarding post-translational modifications of this enzyme that may regulate its activity, intracellular localization and st...

journal_title：World journal of gastroenterology

authors： Prieto P,Jaén RI,Calle D,Gómez-Serrano M,Núñez E,Fernández-Velasco M,Martín-Sanz P,Alonso S,Vázquez J,Cerdán S,Peinado MÁ,Boscá L

更新日期：2019-01-28 00:00:00