Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.

abstract：:Celiac disease (CD) is a permanent auto-immune enteropathy, triggered in genetically predisposed individuals by the ingestion of dietary gluten. Gluten is the alcohol-soluble protein component of the cereals wheat, rye and barley. CD is a multifactorial condition, originating from the interplay of genetic and environm...

journal_title：World journal of gastroenterology

authors： Silano M,Agostoni C,Guandalini S

更新日期：2010-04-28 00:00:00

abstract：AIM:To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection. METHODS:From January 2000 to December 2011, 195 patients underwent pancreatic resection in our hospital. The prognostic factors after pancreatic resection were analyzed in all ...

journal_title：World journal of gastroenterology

authors： Yamamoto T,Yagi S,Kinoshita H,Sakamoto Y,Okada K,Uryuhara K,Morimoto T,Kaihara S,Hosotani R

更新日期：2015-01-07 00:00:00

abstract：:Bacterial colonization of the gut shapes both the local and the systemic immune response and is implicated in the modulation of immunity in both healthy and disease states. Recently, quantitative and qualitative changes in the composition of the gut microbiota have been detected in Crohn's disease and ulcerative colit...

journal_title：World journal of gastroenterology

authors： Rapozo DC,Bernardazzi C,de Souza HS

更新日期：2017-03-28 00:00:00

abstract：AIM:To explore the correlation between expression of somatostatin (SS), gastrin (GAS) and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. METHODS:Sixty-two large intestine cancer tissue samples were randomly and retrospectively selected from patients with large intestine carcinoma. Immunohistoch...

journal_title：World journal of gastroenterology

authors： Mao JD,Wu P,Xia XH,Hu JQ,Huang WB,Xu GQ

更新日期：2005-02-07 00:00:00

abstract：AIM:To evaluate tumor necrosis factor-α converting enzyme (TACE) methylation status in patients with chronic hepatitis B (CHB). METHODS:Eighty patients with hepatitis B e antigen (HBeAg)-positive CHB, 80 with HBeAg-negative CHB, and 40 healthy controls (HCs) were randomly enrolled in this study. Genomic DNA was extrac...

journal_title：World journal of gastroenterology

authors： Wang ZL,Gao S,Li XY,Sun FK,Li F,Fan YC,Wang K

更新日期：2015-07-21 00:00:00

abstract：BACKGROUND:Identifying predictors of therapeutic response is the cornerstone of personalized medicine. AIM:To identify predictors of long-term mucosal healing (MH) in patients with Crohn's disease (CD) treated with tumor necrosis factor α (TNF-α) inhibitors. METHODS:Prospective single center study. Consecutive patien...

journal_title：World journal of gastroenterology

authors： Alfaro I,Masamunt MC,Planell N,López-García A,Castro J,Gallego M,Barastegui R,Giner A,Vara A,Salas A,Ricart E,Panés J,Ordás I

更新日期：2019-04-14 00:00:00

abstract：:Infection with hepatitis B virus is an important health problem worldwide: it affects more than 350 million people and is a leading cause of liver-related morbidity, accounting for 1 million deaths annually. Hepatic fibrosis is a consequence of the accumulation of extracellular matrix components in the liver. An accur...

journal_title：World journal of gastroenterology

authors： Enomoto M,Morikawa H,Tamori A,Kawada N

更新日期：2014-09-14 00:00:00

abstract：BACKGROUND:The formation of liver fibrosis is mainly caused by the activation of hepatic stellate cells (HSCs) and the imbalance of extracellular matrix (ECM) production and degradation. The treatment of liver fibrosis mainly includes removing the cause, inhibiting the activation of HSCs, and inhibiting inflammation. N...

journal_title：World journal of gastroenterology

authors： Zhang YZ,Yao JN,Zhang LF,Wang CF,Zhang XX,Gao B

更新日期：2019-06-28 00:00:00

abstract：AIM:To clarify the role of neoadjuvant concurrent chemoradiotherapy (NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma (CCA). METHODS:We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients receiv...

journal_title：World journal of gastroenterology

authors： Jung JH,Lee HJ,Lee HS,Jo JH,Cho IR,Chung MJ,Park JY,Park SW,Song SY,Bang S

更新日期：2017-05-14 00:00:00

abstract：AIM:To see the possibility of avoiding routine colostomy in patients presenting with unprepared bowel. METHODS:The cohort is composed of 103 patients, of these, 86 patients presented as emergencies (self-inflected and iatrogenic colon injuries, stab wounds and blast injury of the colon, volvulus sigmoid, obstructing l...

journal_title：World journal of gastroenterology

authors： Asfar SK,Al-Sayer HM,Juma TH

更新日期：2007-06-21 00:00:00

abstract：:Mastocytosis is a clonal neoplastic disorder of the mast cells (MC) that can be limited to the skin (cutaneous mastocytosis) or involve one or more extracutaneous organs (systemic mastocytosis). The clinical manifestations of mastocytosis are heterogeneous ranging from indolent disease with a long-term survival to a h...

journal_title：World journal of gastroenterology

authors： Martins C,Teixeira C,Ribeiro S,Trabulo D,Cardoso C,Mangualde J,Freire R,Gamito É,Alves AL,Cremers I,Alves C,Neves A,Oliveira AP

更新日期：2016-07-28 00:00:00

abstract：AIM:We shall construct the small interfering RNA (siRNA) expression cassette (SEC) targeting activated K-ras gene sequence, identify more effective siRNA sequence against K-ras gene in human pancreatic cancer cell line MiaPaCa-2 by SEC and reveal the anti-cancer effects of RNA interference (RNAi) and its therapeutic po...

journal_title：World journal of gastroenterology

authors： Wang W,Wang CY,Dong JH,Chen X,Zhang M,Zhao G

更新日期：2005-04-07 00:00:00

abstract：AIM:To investigate the effect of a fat rich diet on non-steroidal anti-inflammatory drug (NSAID)-induced mucosal damage in the murine small intestine. METHODS:C57BL6 mice were fed 4 types of diets with or without indomethacin. One group was fed standard laboratory chow. The other groups were fed a fat diet consisting ...

journal_title：World journal of gastroenterology

authors： Ueda T,Hokari R,Higashiyama M,Yasutake Y,Maruta K,Kurihara C,Tomita K,Komoto S,Okada Y,Watanabe C,Usui S,Nagao S,Miura S

更新日期：2015-01-07 00:00:00

abstract：AIM:To describe a new clinical and pathological subtype of microscopic colitis in children. METHODS:A selected group of children with abdominal pain, constipation and/or diarrhoea showing discrete or no macroscopic abnormalities on endoscopy was described. RESULTS:Multiple biopsies of colon showed large mononuclear c...

journal_title：World journal of gastroenterology

authors： Józefczuk J,Wozniewicz BM

更新日期：2008-01-14 00:00:00

abstract：:The normal esophageal mucosa creates a protective epithelial barrier that constrains the acidic reflux in the esophageal lumen. Microscopic findings and functional studies indicate that this barrier might be impaired in patients with non erosive reflux disease (NERD) but not in patients with functional heartburn (FH)....

journal_title：World journal of gastroenterology

authors： Triantos C,Koukias N,Karamanolis G,Thomopoulos K

更新日期：2015-05-21 00:00:00

abstract：AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

journal_title：World journal of gastroenterology

authors： Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

更新日期：2008-11-14 00:00:00

abstract：:An insufficient future liver remnant (FLR) is associated with post-hepatectomy liver failure. Associating liver partition and portal vein ligation for stage hepatectomy (ALPPS) has been shown to be effective for the induction of rapid FLR hypertrophy so as to improve the resectability in patients with insufficient FLR...

journal_title：World journal of gastroenterology

authors： Chan A,Chung PH,Poon RT

更新日期：2014-08-07 00:00:00

abstract：AIM:To investigate the antioxidant effect of caffeic acid phenethyl ester (CAPE) in hepatic stellate cell-T6 (HSC-T6) cells cultured in vitro and the potential mechanisms. METHODS:HSC-T6 cells were cultured in vitro and treated with various concentrations of CAPE for 24, 48 and 72 h, respectively. Cell proliferation w...

journal_title：World journal of gastroenterology

authors： Yang N,Shi JJ,Wu FP,Li M,Zhang X,Li YP,Zhai S,Jia XL,Dang SS

更新日期：2017-02-21 00:00:00

abstract：AIM:To evaluate the efficacy of 5 compared to 10 granulocyteaphaeresis sessions in patients with active steroid-dependent ulcerative colitis. METHODS:In this pilot, prospective, multicenter randomized trial, 20 patients with moderately active steroid-dependent ulcerative colitis were randomized to 5 or 10 granulocytea...

journal_title：World journal of gastroenterology

authors： Ricart E,Esteve M,Andreu M,Casellas F,Monfort D,Sans M,Oudovenko N,Lafuente R,Panes J

更新日期：2007-04-21 00:00:00

abstract：BACKGROUND:Laparoscopy has been widely used in general surgical procedures, but total laparoscopic pancreaticoduodenectomy (TLPD) is still a complex and challenging surgery that is only performed in a small number of patients at a few large academic medical centers. Although the safety and feasibility of TLPD have been...

journal_title：World journal of gastroenterology

authors： Zhang H,Lan X,Peng B,Li B

更新日期：2019-10-07 00:00:00

abstract：AIM:To investigate the association between the tag single nucleotide polymorphisms (TagSNPs) of NOD1 and NOD2 and the risk of developing gastric cancer. METHODS:We conducted a hospital-based case-control study including 296 incident gastric cancer patients and 160 gastritis controls. Eight TagSNPs in the NOD1 and NOD2...

journal_title：World journal of gastroenterology

authors： Wang P,Zhang L,Jiang JM,Ma D,Tao HX,Yuan SL,Wang YC,Wang LC,Liang H,Zhang ZS,Liu CJ

更新日期：2012-05-07 00:00:00

abstract：:We report a case of duodenal varix bleeding as a long term complication of balloon occluded retrograde transvenous obliteration (BRTO), which was successfully treated with a transjugular intrahepatic portosystemic shunt (TIPS). A 57-year-old man was admitted to the emergency room suffering from melena. He had undergon...

journal_title：World journal of gastroenterology

authors： Kim MJ,Jang BK,Chung WJ,Hwang JS,Kim YH

更新日期：2012-06-14 00:00:00

abstract：AIM:To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS:A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column, and the cord segments C(4-6) and gastric antrum we...

journal_title：World journal of gastroenterology

authors： Song PS,Kong KM,Niu CY,Qi WL,Wu LF,Wang XJ,Han W,Huang K,Chen ZF

更新日期：2005-01-28 00:00:00

abstract：AIM:To evaluate the effect of the shunting branch of the portal vein (PV) (left or right) and the initial stent position (optimal or suboptimal) of a transjugular intrahepatic portosystemic shunt (TIPS). METHODS:We retrospectively reviewed 307 consecutive cirrhotic patients who underwent TIPS placement for variceal bl...

journal_title：World journal of gastroenterology

authors： Bai M,He CY,Qi XS,Yin ZX,Wang JH,Guo WG,Niu J,Xia JL,Zhang ZL,Larson AC,Wu KC,Fan DM,Han GH

更新日期：2014-01-21 00:00:00

abstract：AIM:To perform a meta-analysis of observational studies to further elucidate the relationship between oral bisphosphonate use and gastrointestinal cancer risk. METHODS:Systematic literature search was conducted in MEDLINE, EMBASE, and the Cochrane Library to identify studies through January 2011. Search terms were "bi...

journal_title：World journal of gastroenterology

authors： Oh YH,Yoon C,Park SM

更新日期：2012-10-28 00:00:00

abstract：:It is reported that a pancreatic disease may precede the diagnosis of inflammatory bowel disease (IBD) both in children and in adults. Idiopathic chronic pancreatitis, however, occasionally co-exists with the IBD, mainly at pediatric age. We report a case of a patient who progressively developed the features of a chro...

journal_title：World journal of gastroenterology

authors： Knafelz D,Panetta F,Monti L,Bracci F,Papadatou B,Torre G,Dall'Oglio L,Diamanti A

更新日期：2013-08-21 00:00:00

abstract：AIM:To investigate the mechanisms of anti-liver fibrosis actions of Fuzheng Huayu (FZHY) decoction, which acts to strengthen the body's resistance and promote blood circulation. METHODS:Ito cells were isolated from rats and cultured. Serum samples were collected from healthy (normal) rats after administration of FZHY ...

journal_title：World journal of gastroenterology

authors： Liu CH,Liu C,Liu P,Xu LM

更新日期：1997-12-15 00:00:00

abstract：:Portal hypertension, one of the vascular diseases, not only has lesions in liver, but also changes in vascular structures and functions of extrahepatic portal system, systemic system and pulmonary circulation. The pathological changes of vasculopathy in portal hypertension include remodeling of arterialized visceral v...

journal_title：World journal of gastroenterology

authors： Li T,Yang Z

更新日期：2005-10-21 00:00:00

abstract：AIM:To investigate the long-term outcomes of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) with a fully covered self-expandable metallic stent (FCSEMS). METHODS:From April 2009 to August 2010, 15 patients with distal malignant biliary obstructions who were candidates for alternative techniques for bili...

journal_title：World journal of gastroenterology

authors： Song TJ,Hyun YS,Lee SS,Park DH,Seo DW,Lee SK,Kim MH

更新日期：2012-08-28 00:00:00

abstract：AIM:To evaluate the efficacy and safety of traditional Chinese surgical treatment for anal fistulae with secondary tracks and abscess. METHODS:Sixty patients with intersphincteric or transsphincteric anal fistulas with secondary tracks and abscess were randomly divided into study group [suture dragging combined with p...

journal_title：World journal of gastroenterology

authors： Wang C,Lu JG,Cao YQ,Yao YB,Guo XT,Yin HQ

更新日期：2012-10-28 00:00:00