Effects of aspirin and enoxaparin in a rat model of liver fibrosis.

abstract：AIM:To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this process. METHODS:Using migration assay, MTT assay and Matrigel assay, the effect of alphastatin on vascular endothelial cells (ECs) was evaluated in vitro. SPK ...

journal_title：World journal of gastroenterology

authors： Chen L,Li T,Li R,Wei B,Peng Z

更新日期：2006-07-14 00:00:00

abstract：AIM:To analyze the effects of NF- kappa B inhibition by antioxidant pyrrolidine dithiocarbamate (PDTC) or TNF inhibitor pentoxifylline (PTX) on liver regeneration after partial hepatectomy (PH). METHODS:Saline, PDTC or PTX were injected 1 h before PH and rats were killed at 0.5 and 24 h after PH. Several control group...

journal_title：World journal of gastroenterology

authors： Laurent S,Horsmans Y,Stärkel P,Leclercq I,Sempoux C,Lambotte L

更新日期：2005-12-14 00:00:00

abstract：:We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-diffe...

journal_title：World journal of gastroenterology

authors： Joo HJ,Kim GH,Jeon WJ,Chae HB,Park SM,Youn SJ,Choi JW,Sung R

更新日期：2009-07-21 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a major cause of cancer-related death, with a 5-year overall survival rate being below 5%. The main causes of poor prognosis in pancreatic cancer include easy metastasis, high recurrence rate, and robust drug resistance. Gemcitabine is a first-line drug for patients with unresectable pan...

journal_title：World journal of gastroenterology

authors： Wei L,Wen JY,Chen J,Ma XK,Wu DH,Chen ZH,Huang JL

更新日期：2019-10-07 00:00:00

abstract：AIM:To investigate the risk association and compare the onset age of hepatocellular carcinoma (HCC) patients in Taiwan with different genotypes of MDM2-SNP309. METHODS:We analyzed MDM2-SNP309 genotypes from 58 patients with HCC and 138 cancer-free healthy controls consecutively. Genotyping of MDM2-SNP309 was conducted...

journal_title：World journal of gastroenterology

authors： Leu JD,Lin IF,Sun YF,Chen SM,Liu CC,Lee YJ

更新日期：2009-11-28 00:00:00

abstract：:Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. A 56-year-old Caucasian male was admitted to our surgical department with a chief complaint of a painful mass in his right lower abdomen for almost 2 years. The physical examinati...

journal_title：World journal of gastroenterology

authors： Wang TB,Dai WG,Liu DW,Shi HP,Dong WG

更新日期：2013-10-21 00:00:00

abstract：:In order to have an adequate view of the whole small intestine during capsule endoscopy, the preparation recommended consists of a clear liquid diet and an overnight fast. However, visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents. To improve mucosal visualization, ...

journal_title：World journal of gastroenterology

authors： Pons Beltrán V,Carretero C,Gonzalez-Suárez B,Fernandez-Urien I,Muñoz-Navas M

更新日期：2008-10-07 00:00:00

abstract：:Crohn's disease (CD) is a multifactorial disorder of unknown cause. Outstanding progress regarding the pathophysiology of CD has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD over the last years. However, many drugs have not been approved by regulatory ...

journal_title：World journal of gastroenterology

authors： Büning C,Lochs H

更新日期：2006-08-14 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertai...

journal_title：World journal of gastroenterology

authors： Zelber-Sagi S,Ratziu V,Oren R

更新日期：2011-08-07 00:00:00

abstract：:AIM:To observe the tumor inhibitory effects by transfecting IL-6 cDNA into colon cancer cell line HT-29 with retroviral vector pZIP cDNA.METHODS:Human IL-6 gene was reconstructed in retrovirus vector and transfected into incasing cells PA317 by lipofectamine mediated method, the clones of the cells transferred with hI...

journal_title：World journal of gastroenterology

authors： Xiao B,Jing B,Zhang YL,Zhou DY,Zhang WD

更新日期：2000-02-01 00:00:00

abstract：:Bone metastases from gastric cancer (GC) are considered a relatively uncommon finding; however, they are related to poorer prognosis. Both primary GC and its metastatic progression rely on angiogenesis. Several lines of evidence from GC patients strongly support the involvement of mast cells (MCs) positive to tryptase...

journal_title：World journal of gastroenterology

authors： Leporini C,Ammendola M,Marech I,Sammarco G,Sacco R,Gadaleta CD,Oakley C,Russo E,De Sarro G,Ranieri G

更新日期：2015-10-07 00:00:00

abstract：AIM:To evaluate the effects of p53 on apoptosis and proliferation of hepatocellular carcinoma (HCC) cells treated with transcatheter arterial chemoembolization (TACE). METHODS:A total of 136 patients with HCC received TACE and other management before surgery were divided into TACE group and non-TACE group. TACE group ...

journal_title：World journal of gastroenterology

authors： Xiao EH,Li JQ,Huang JF

更新日期：2004-01-15 00:00:00

abstract：AIM:To construct tree models for classification of diffuse large B-cell lymphomas (DLBCL) by chromosome copy numbers, to compare them with cDNA microarray classification, and to explore models of multi-gene, multi-step and multi-pathway processes of DLBCL tumorigenesis. METHODS:Maximum-weight branching and distance-ba...

journal_title：World journal of gastroenterology

authors： Jiang HY,Huang ZX,Zhang XF,Desper R,Zhao T

更新日期：2007-03-21 00:00:00

abstract：AIM:To study the association between exposure to Salmonella enterica (SE) and Crohn's disease (CD) and its clinical implications in Chilean patients. METHODS:Ninety-four unrelated Chilean CD patients from CAREI (Active Cohort Registry of Inflammatory Bowel Disease) presenting to a single inflammatory bowel disease (IB...

journal_title：World journal of gastroenterology

authors： Alvarez-Lobos M,Pizarro DP,Palavecino CE,Espinoza A,Sebastián VP,Alvarado JC,Ibañez P,Quintana C,Díaz O,Kalergis AM,Bueno SM

更新日期：2013-09-21 00:00:00

abstract：AIM:To investigate and characterise patients with chronic hepatitis C virus (HCV) infection presenting with hepatocellular carcinoma (HCC) in the absence of cirrhosis. METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified. The clinical case notes...

journal_title：World journal of gastroenterology

authors： Nash KL,Woodall T,Brown AS,Davies SE,Alexander GJ

更新日期：2010-08-28 00:00:00

abstract：:We report a case of a patient presenting with clinical, radiological and endoscopic features of colitis due to a compressive left para-aortic mass. Total open surgical excision was performed, which resulted in complete resolution of colitis. Histopathology and immunohistochemistry revealed benign retroperitoneal schwa...

journal_title：World journal of gastroenterology

authors： Fass G,Hossey D,Nyst M,Smets D,Saligheh EN,Duttmann R,Claes K,da Costa PM

更新日期：2007-11-07 00:00:00

abstract：AIM:To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis (UC), and their effect on inflammatory mediators and nuclear factor (NF)-kappaB activation in these patients. METHODS:Thirty patients with mild to moderate UC were randomly classified into two groups: sulfasalazine group, who r...

journal_title：World journal of gastroenterology

authors： Hegazy SK,El-Bedewy MM

更新日期：2010-09-07 00:00:00

abstract：AIM:To analyze the clinicopathologic features and the prognosis of primary intestinal lymphoma. METHODS:Patients were included in the study based on standard diagnostic criteria for primary gastrointestinal lymphoma, and were treated at Sun Yat-sen University Cancer Centre between 1993 and 2008. RESULTS:The study com...

journal_title：World journal of gastroenterology

authors： Wang GB,Xu GL,Luo GY,Shan HB,Li Y,Gao XY,Li JJ,Zhang R

更新日期：2011-11-07 00:00:00

abstract：AIM:To assess the clinical outcomes of pre-, pro- and synbiotics therapy in patients with acute pancreatitis. METHODS:The databases including Medline, Embase, the Cochrane Library, Web of Science and Chinese Biomedicine Database were searched for all relevant randomized controlled trials that studied the effects of pr...

journal_title：World journal of gastroenterology

authors： Zhang MM,Cheng JQ,Lu YR,Yi ZH,Yang P,Wu XT

更新日期：2010-08-21 00:00:00

abstract：:This paper pays a tribute to Dr. Frank I Tovey on his 90th birthday which happens on September 1, 2011, and briefly describes the major findings in his research career and contributions as follows. The geographical prevalence of duodenal ulceration is related to staple diets. Unrefined wheat and maize, soya, certain p...

journal_title：World journal of gastroenterology

authors： Ma LS

更新日期：2011-08-21 00:00:00

abstract：:Peritoneal dissemination represents a devastating form of gastric cancer (GC) progression with a dismal prognosis. There is no effective therapy for this condition. The 5-year survival rate of patients with peritoneal dissemination is 2%, even including patients with only microscopic free cancer cells without macrosco...

journal_title：World journal of gastroenterology

authors： Kanda M,Kodera Y

更新日期：2016-08-14 00:00:00

abstract：:Repeated surveys from Europe, the United States, Australia, and New Zealand have shown that adherence to an evidence-based perioperative care protocol, such as Enhanced Recovery After Surgery (ERAS), has been generally low. It is of great importance to support the implementation of the ERAS protocol as it has been sho...

journal_title：World journal of gastroenterology

authors： Segelman J,Nygren J

更新日期：2014-11-28 00:00:00

abstract：:Cystic formations within the liver are a frequent finding among populations. Besides the common cystic lesions, like simple liver cysts, rare cystic liver lesions like cystadenocarcinoma should also be considered in the differential diagnosis. Thorough knowledge of each entity's nature and course are key elements to s...

journal_title：World journal of gastroenterology

authors： Bakoyiannis A,Delis S,Triantopoulou C,Dervenis C

更新日期：2013-11-21 00:00:00

abstract：:Colorectal cancer (CRC) remains one of the major public health problems throughout the world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over several years and progresses through cytologically distinct benign and malignant states, from single crypt lesions through adenoma, to malignant ...

journal_title：World journal of gastroenterology

authors： Grizzi F,Bianchi P,Malesci A,Laghi L

更新日期：2013-01-14 00:00:00

abstract：AIM:To assess the incidence of hepatocellular carcinoma (HCC) in chronic liver disease due to hepatitis B virus (HBV) or hepatitis C virus (HCV) coinfected with human immunodeficiency virus (HIV). METHODS:A retrospective cohort study was performed, including patients with chronic liver disease due to HBV or HCV, with ...

journal_title：World journal of gastroenterology

authors： Marcon PDS,Tovo CV,Kliemann DA,Fisch P,de Mattos AA

更新日期：2018-02-07 00:00:00

abstract：AIM:To establish an ideal implantable rat liver tumor model for interventional therapy study and examine its angiographic signs and MRI, CT features before and after embolization. METHODS:Forty male Wistar rats were implanted with Walker-256 tumor in the left lateral lobe of liver. Digital subtraction angiography (DSA...

journal_title：World journal of gastroenterology

authors： Li X,Zheng CS,Feng GS,Zhuo CK,Zhao JG,Liu X

更新日期：2002-12-01 00:00:00

abstract：AIM:To conduct a prospective assessment of anti-hepatitis E virus (HEV) IgG seroprevalence in the Western Cape Province of South Africa in conjunction with evaluating risk factors for exposure. METHODS:Consenting participants attending clinics and wards of Groote Schuur, Red Cross Children's Hospital and their affilia...

journal_title：World journal of gastroenterology

authors： Madden RG,Wallace S,Sonderup M,Korsman S,Chivese T,Gavine B,Edem A,Govender R,English N,Kaiyamo C,Lutchman O,van der Eijk AA,Pas SD,Webb GW,Palmer J,Goddard E,Wasserman S,Dalton HR,Spearman CW

更新日期：2016-11-28 00:00:00

abstract：AIM:To describe the learning curves of hand-assisted laparoscopic D2 radical gastrectomy (HALG) for the treatment of gastric cancer. METHODS:The HALG surgical procedure consists of three stages: surgery under direct vision via the port for hand assistance, hand-assisted laparoscopic surgery, and gastrointestinal tract...

journal_title：World journal of gastroenterology

authors： Gong JQ,Cao YK,Wang YH,Zhang GH,Wang PH,Luo GD

更新日期：2015-02-07 00:00:00

abstract：:We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

journal_title：World journal of gastroenterology

authors： Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

更新日期：2008-03-28 00:00:00

abstract：:Although gastric cancer (GC) is one of the leading causes of cancer-related death, major therapeutic advances have not been made, and patients with GC still face poor outcomes. The prognosis of GC also remains poor because the molecular mechanisms of GC progression are incompletely understood. MicroRNAs (miRNAs) are n...

journal_title：World journal of gastroenterology

authors： Ishiguro H,Kimura M,Takeyama H

更新日期：2014-05-21 00:00:00