No evidence demonstrating hepatotoxicity associated with hydroxycitric acid.

abstract：:Anorectal melanoma is a very rare tumor with poor prognosis. Rectal bleeding is the most frequent symptom and surgical treatment ranges from local excision to radical abdominoperineal resection. We report a case of a 75-years-old male patient who presented with a history of recurrent rectal bleeding, and whose histopa...

journal_title：World journal of gastroenterology

authors： Balicevic D,Tomic K,Bekavac-Beslin M,Kovacevic I,Mijic A,Belicza M,Kruslin B

更新日期：2006-06-07 00:00:00

abstract：:Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do not respond to therapy and others lose response over time. The pharmacokinetic properties of these drugs...

journal_title：World journal of gastroenterology

authors： Yarur AJ,Abreu MT,Deshpande AR,Kerman DH,Sussman DA

更新日期：2014-04-07 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：:Esophageal cancer is an aggressive malignancy associated with dismal treatment outcomes. Presence of two distinct histopathological types distinguishes it from other gastrointestinal tract malignancies. Surgery is the cornerstone of treatment in locally advanced esophageal cancer (T2 or greater or node positive); howe...

journal_title：World journal of gastroenterology

authors： Garg PK,Sharma J,Jakhetiya A,Goel A,Gaur MK

更新日期：2016-10-21 00:00:00

abstract：AIM:To clarify the relationship between circumferential resection margin status and local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma. The relationship between circumferential resection margin status and clinicopathologic characteristics of middle and lower rectal carci...

journal_title：World journal of gastroenterology

authors： Wu ZY,Wan J,Li JH,Zhao G,Peng L,Yao Y,Du JL,Liu QF,Wang ZD,Huang ZM,Lin HH

更新日期：2007-06-28 00:00:00

abstract：AIM:To explore molecular mechanism of nicotinamide adenine dinucleotide (NADH) antagonization against X-ray induced L02 cells damage. METHODS:L02 liver cells were cultured in RPMI 1640, exposed to X-ray irradiation and continued to culture in the presence or absence of NADH. Cellular viability was analyzed by routine ...

journal_title：World journal of gastroenterology

authors： Liu FQ,Zhang JR

更新日期：2003-08-01 00:00:00

abstract：:Despite advancements in medical therapy of Crohn's disease (CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for sur...

journal_title：World journal of gastroenterology

authors： Toh JW,Stewart P,Rickard MJ,Leong R,Wang N,Young CJ

更新日期：2016-10-28 00:00:00

abstract：AIM:To investigate the role of enhancer of zeste homologue 2 (EZH2) and STAT6 immunohistochemistry in the evaluation of clinical stages and prognosis of colorectal cancer (CRC). METHODS:The expression patterns were examined by immunohistochemistry in both tumor and adjacent non-neoplastic tissues of 119 CRC patients w...

journal_title：World journal of gastroenterology

authors： Wang CG,Ye YJ,Yuan J,Liu FF,Zhang H,Wang S

更新日期：2010-05-21 00:00:00

abstract：AIM:To evaluate the association between acid suppressive drug use and the development of gastric cancer. METHODS:A systematic search of relevant studies that were published through June 2012 was conducted using the MEDLINE (PubMed), EMBASE, and Cochrane Library databases. The search included observational studies on t...

journal_title：World journal of gastroenterology

authors： Ahn JS,Eom CS,Jeon CY,Park SM

更新日期：2013-04-28 00:00:00

abstract：AIM:To investigate the aberrant expression of nuclear matrix proteins in human gastric cancer cells before and after hexamethylene bisacetamide (HMBA) treatment. METHODS:Proteomics analysis of differential nuclear matrix proteins was performed by two dimensional electrophoresis polyacrylamide gel electrophoresis and m...

journal_title：World journal of gastroenterology

authors： Jing GJ,Xu DH,Shi SL,Li QF,Wang SY,Wu FY,Kong HY

更新日期：2010-05-07 00:00:00

abstract：:Alcoholic fatty liver disease (AFLD), a potentially pathologic condition, can progress to steatohepatitis, fibrosis, and cirrhosis, leading to an increased probability of hepatic failure and death. Alcohol induces fatty liver by increasing the ratio of reduced form of nicotinamide adenine dinucleotide to oxidized form...

journal_title：World journal of gastroenterology

authors： Liu J

更新日期：2014-10-28 00:00:00

abstract：AIM:To investigate the relationship between certain biochemical parameters of lipid metabolism in the serum and steatosis in the liver. METHODS:The grade of steatosis (0-3) and histological activity index (HAI, 0-18) in liver biopsy specimens were correlated with serum alanine aminotransferase (ALT), total cholesterol...

journal_title：World journal of gastroenterology

authors： Jármay K,Karácsony G,Nagy A,Schaff Z

更新日期：2005-11-07 00:00:00

abstract：:AIM:To assess the diagnostic values of tumor markers for pancreatic cancer.METHODS:Pancreatic cancer-associated antigen from colonic mucosa (PCAAc), pancreas-specific antigen (PaA), pancreatic oncofetal antigen (POA) and minimolecular pancreatic antigen (mPOA) were detected by double antibodies Sandwich ELISA; CA19-9,...

journal_title：World journal of gastroenterology

authors： Zhao XY,Yu SY,Da SP,Bai L,Guo XZ,Dai XJ,Wang YM

更新日期：1998-04-01 00:00:00

abstract：:Weight loss supplements often contain powerful pharmacoactive ingredients with the potential to cause harm. Trials used to determine product safety and effectiveness, meanwhile, tend to be small, of short duration, and frequently lack financial conflict of interest disclosures. These factors could conspire to place co...

journal_title：World journal of gastroenterology

authors： Lobb A

更新日期：2010-10-14 00:00:00

abstract：AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

journal_title：World journal of gastroenterology

authors： Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

更新日期：2007-08-21 00:00:00

abstract：BACKGROUND:Stress-related gastric mucosal damage or ulcer remains an unsolved issue for critically ill patients. Stress ulcer prophylaxis has been part of routine intensive care, but uncertainty and controversy still exist. Co-secreted with mucins, intestinal trefoil factor (ITF) is reported to promote restitution and ...

journal_title：World journal of gastroenterology

authors： Huang Y,Wang MM,Yang ZZ,Ren Y,Zhang W,Sun ZR,Nie SN

更新日期：2020-12-28 00:00:00

abstract：AIM:To investigate the possible clinical application value of second harmonic imaging under low acoustic pressure. METHODS:Six New Zealand rabbits, averaging 2.7+/-0.4 kg, were selected and operated upon to construct hepatic VX2 tumor carrier model. Hepatic VX2 tumors were imaged with B mode Ultrasonography (US), and ...

journal_title：World journal of gastroenterology

authors： Du WH,Yang WX,Wang X,Xiong XQ,Zhou Y,Li T

更新日期：2003-08-01 00:00:00

abstract：:Adult to adult living donor liver transplantation (AALDLT) was first preformed in the United States in 1997. The procedure was rapidly integrated into clinical practice, but in 2002, possibly due to the first widely publicized donor death, the number of living liver donors plummeted. The number of donors has since rea...

journal_title：World journal of gastroenterology

authors： Carlisle EM,Testa G

更新日期：2012-12-14 00:00:00

abstract：:Total mesorectal excision (TME) is the standard treatment for rectal cancer, but complications are frequent and rates of morbidity, mortality and genitourinary alterations are high. Transanal endoscopic microsurgery (TEM) allows preservation of the anal sphincters and, via its vision system through a rectoscope, allow...

journal_title：World journal of gastroenterology

authors： Serra-Aracil X,Mora-Lopez L,Alcantara-Moral M,Caro-Tarrago A,Gomez-Diaz CJ,Navarro-Soto S

更新日期：2014-09-07 00:00:00

abstract：AIM:Intrabiliary rupture (IBR) is a common and serious complication of hepatic hydatid cyst. The incidence varies from 1% to 25%. The treatment of IBR is still controversial. We aimed to design an algorithm for the treatment of hepatic hydatidosis with IBR by reviewing our cases. METHODS:Eight cases of IBR were analyz...

journal_title：World journal of gastroenterology

authors： Erzurumlu K,Dervisoglu A,Polat C,Senyurek G,Yetim I,Hokelek M

更新日期：2005-04-28 00:00:00

abstract：AIM:It has been reported that regular consumption of nonsteroidal anti-inflammatory drugs like indomethacin decreases the incidence and mortality rate of a number of gastrointestinal cancers. We aimed to explore the efficacy and possible mechanisms of indomethacin on tumor growth and tumor angiogenesis of human colon c...

journal_title：World journal of gastroenterology

authors： Wang HM,Zhang GY

更新日期：2005-01-21 00:00:00

abstract：:While conservative management such as fluid, bowel rest, and antibiotics is the mainstay of current acute pancreatitis management, there is a lot of promise in pharmacologic therapies that target various aspects of the pathogenesis of pancreatitis. Extensive review of preclinical studies, which include assessment of t...

journal_title：World journal of gastroenterology

authors： Kambhampati S,Park W,Habtezion A

更新日期：2014-12-07 00:00:00

abstract：AIM:To investigate the effects of Terminalia arjuna (T. arjuna) extract on human hepatoma cell line (HepG2) and its possible role in induction of apoptosis. METHODS:Human hepatoma cells were treated with different concentrations of ethanolic extract of T. arjuna and its cytotoxicity effect was measured by trypan blue ...

journal_title：World journal of gastroenterology

authors： Sivalokanathan S,Vijayababu MR,Balasubramanian MP

更新日期：2006-02-21 00:00:00

abstract：AIM:To compare the efficacy of different chemotherapeutic agents during conventional transarterial chemoembolization (cTACE) in the treatment of unresectable hepatocellular carcinoma (HCC). METHODS:A retrospective review was undertaken of patients with unresectable HCC undergoing cTACE from May 2003 to November 2011. ...

journal_title：World journal of gastroenterology

authors： Wu J,Song L,Zhao DY,Guo B,Liu J

更新日期：2014-08-21 00:00:00

abstract：AIM:To evaluate the effect of long-term treatment with leukocyte natural α-interferon (ln-α-IFN) plus ribavirin (RBV). METHODS:Forty-six patients with hepatitis C virus (HCV) recurrence received 3 MU three times a week of ln-α-IFN plus RBV for 1 mo; then, patients with good tolerability (n = 30) were switched to daily...

journal_title：World journal of gastroenterology

authors： Tamè M,Buonfiglioli F,Del Gaudio M,Lisotti A,Cecinato P,Colecchia A,Azzaroli F,D'Errico A,Arena R,Calvanese C,Quarneti C,Ballardini G,Pinna AD,Mazzella G

更新日期：2013-08-28 00:00:00

abstract：:The origin of inflammatory bowel disease is unknown. Attempts have been made to isolate a microorganism that could explain the onset of inflammation, but no pathological agent has ever been identified. Johne's disease is a granulomatous chronic enteritis of cattle and sheep caused by Mycobacterium avium subspecies par...

journal_title：World journal of gastroenterology

authors： Liverani E,Scaioli E,Cardamone C,Dal Monte P,Belluzzi A

更新日期：2014-09-28 00:00:00

abstract：:Helicobacter pylori (H pylori), a gastric pathogen, is a major cause of chronic gastritis and peptic ulcer disease, and is an important risk factor for the development of gastric malignancies. Culture of the bacterium from gastric biopsy is essential for the determination of drug resistance of H pylori. However, the i...

journal_title：World journal of gastroenterology

authors： Yin Y,He LH,Zhang JZ

更新日期：2009-03-28 00:00:00

abstract：:Schwannomas are mesenchymal tumors originating from Schwann cells in peripheral nerve sheaths. Although the tumor can be located in any part of the human body, the most common locations are the head, neck, trunk and extremities. Pancreatic schwannomas are rare. To our knowledge, only 64 cases of pancreatic schwannoma ...

journal_title：World journal of gastroenterology

authors： Xu SY,Sun K,Owusu-Ansah KG,Xie HY,Zhou L,Zheng SS,Wang WL

更新日期：2016-10-07 00:00:00

abstract：AIM:To assess the clinical outcomes of pre-, pro- and synbiotics therapy in patients with acute pancreatitis. METHODS:The databases including Medline, Embase, the Cochrane Library, Web of Science and Chinese Biomedicine Database were searched for all relevant randomized controlled trials that studied the effects of pr...

journal_title：World journal of gastroenterology

authors： Zhang MM,Cheng JQ,Lu YR,Yi ZH,Yang P,Wu XT

更新日期：2010-08-21 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00