Current research and treatment for gastrointestinal stromal tumors.

abstract：:Eosinophilic oesophagitis (EoE) is a chronic, antigen mediated disease of the disease of the oesophagus that may present in both adults and children. It is characterised by intermittent dysphagia, food bolus obstruction and weight loss. The pathogenesis is incompletely understood but is thought to culminate in poor co...

journal_title：World journal of gastroenterology

authors： Attwood SE,Wilson MS

更新日期：2013-02-14 00:00:00

abstract：AIM:To clarify the effectiveness of plasma exchange by comparing the mortality and morbidity before and after the intervention of plasma exchange. METHODS:Plasma exchange has been available as an optional therapy for hyperlipidemic pancreatitis since August 1999 in our hospital. The patients were assorted into 2 group...

journal_title：World journal of gastroenterology

authors： Chen JH,Yeh JH,Lai HW,Liao CS

更新日期：2004-08-01 00:00:00

abstract：:AIM:To study the anticarcinogenic effect and acute toxicity of liver targeting mitoxantrone nanospheres.METHODS:The anticarcinogenic effect of mitoxan-trone polybutylcyanoacrylate nanoparticles (DHAQ-PBCA-NP) was investigated by using heterotopic and orthotopic transplantation models of human hepatocellular carcinoma ...

journal_title：World journal of gastroenterology

authors： Zhang ZR,He Q,Liao GT,Bai SH

更新日期：1999-12-01 00:00:00

abstract：AIM:To estimate the incidence of catheter tract implantation metastasis among patients undergoing percutaneous transhepatic biliary drainage (PTBD) for extrahepatic cholangiocarcinoma, and to provide data regarding the management of this unusual complication of PTBD by reviewing cases reported in the literature. METHO...

journal_title：World journal of gastroenterology

authors： Sakata J,Shirai Y,Wakai T,Nomura T,Sakata E,Hatakeyama K

更新日期：2005-11-28 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：:Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of me...

journal_title：World journal of gastroenterology

authors： Kawai S,Nishida T,Hayashi Y,Ezaki H,Yamada T,Shinzaki S,Miyazaki M,Nakai K,Yakushijin T,Watabe K,Iijima H,Tsujii M,Nishida K,Takehara T

更新日期：2013-03-07 00:00:00

abstract：AIM:To investigate the biological effects of internal irradiation, and the therapeutic effectiveness was assessed of (131)I-labeled anti-epidermal growth factor receptor (EGFR) liposomes, derived from cetuximab, when used as a tumor-targeting carrier in a colorectal cancer mouse model. METHODS:We described the liposom...

journal_title：World journal of gastroenterology

authors： Li W,Ji YH,Li CX,Liu ZY,Li N,Fang L,Chang J,Tan J

更新日期：2016-04-14 00:00:00

abstract：AIM:It has been reported that regular consumption of nonsteroidal anti-inflammatory drugs like indomethacin decreases the incidence and mortality rate of a number of gastrointestinal cancers. We aimed to explore the efficacy and possible mechanisms of indomethacin on tumor growth and tumor angiogenesis of human colon c...

journal_title：World journal of gastroenterology

authors： Wang HM,Zhang GY

更新日期：2005-01-21 00:00:00

abstract：:Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary to more recent availability of newer i...

journal_title：World journal of gastroenterology

authors： Karmacharya P,Aryal MR,Donato A

更新日期：2013-11-21 00:00:00

abstract：AIM:To investigate the expression of mitogen-activated protein kinases (MAPKs) and its upstream protein kinase in human gastric cancer and to evaluate the relationship between protein levels and clinicopathological parameters. METHODS:Western blot was used to measure the expression of extracellular signal-regulated ki...

journal_title：World journal of gastroenterology

authors： Liang B,Wang S,Zhu XG,Yu YX,Cui ZR,Yu YZ

更新日期：2005-02-07 00:00:00

abstract：AIM:To investigate the risk association and compare the onset age of hepatocellular carcinoma (HCC) patients in Taiwan with different genotypes of MDM2-SNP309. METHODS:We analyzed MDM2-SNP309 genotypes from 58 patients with HCC and 138 cancer-free healthy controls consecutively. Genotyping of MDM2-SNP309 was conducted...

journal_title：World journal of gastroenterology

authors： Leu JD,Lin IF,Sun YF,Chen SM,Liu CC,Lee YJ

更新日期：2009-11-28 00:00:00

abstract：AIM:To study the anti-hepatofibrosis mechanism of Bie Jia Jian oral liquid (BOL). METHODS:The model was induced by subcutaneous injection of CCl(4). BOL was administered and the change of serum hyaluronic acid (HA) and laminin (LN) was observed and the degeneration of liver cells and the degree of fibre hyperplasia an...

journal_title：World journal of gastroenterology

authors： Yao L,Yao ZM,Yu T

更新日期：2001-12-01 00:00:00

abstract：:Enzymatic metabolism of the 20C polyunsaturated fatty acid (PUFA) arachidonic acid (AA) occurs via the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, and leads to the production of various bioactive lipids termed eicosanoids. These eicosanoids have a variety of functions, including stimulation of homeostatic re...

journal_title：World journal of gastroenterology

authors： Tuncer S,Banerjee S

更新日期：2015-11-07 00:00:00

abstract：AIM:To investigate the role of transforming growth factor (TGF)-β-inducible early gene 1 (TIEG1) in TGF-β-induced growth inhibition in hepatocellular carcinoma (HCC) cells. METHODS:Human hepatocyte and HCC cell lines with varied susceptibilities to TGF-β1 were tested by methylthiazoletetrazolium (MTT) assay. The expre...

journal_title：World journal of gastroenterology

authors： Jiang L,Lai YK,Zhang JF,Chan CY,Lu G,Lin MC,He ML,Li JC,Kung HF

更新日期：2012-05-07 00:00:00

abstract：AIM:To determine whether bispectral index (BIS) monitoring is useful for propofol administration for deep sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:Fifty-nine consecutive patients with a variety of reasons for ERCP who underwent the procedure at least twice between 1 July 2010 and ...

journal_title：World journal of gastroenterology

authors： Jang SY,Park HG,Jung MK,Cho CM,Park SY,Jeon SW,Tak WY,Kweon YO,Kim SK,Jeon YH

更新日期：2012-11-21 00:00:00

abstract：:Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and eve...

journal_title：World journal of gastroenterology

authors： Pimenta AP,Preto JR,Gouveia AM,Fonseca E,Pimenta MM

更新日期：2007-12-07 00:00:00

abstract：:Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postopera...

journal_title：World journal of gastroenterology

authors： Zhang GF,Chai Y,Li WS,Huang LS,Shen G

更新日期：2014-09-21 00:00:00

abstract：:The incidence of gastric cancer remains high in South Korea. Upper gastrointestinal (GI) endoscopy, i.e., esophagogastroduodenoscopy (EGD), has a higher diagnostic specificity and sensitivity than the upper GI series. Additionally, EGD has the ability to biopsy, through taking a tissue of the pathologic lesion. Succes...

journal_title：World journal of gastroenterology

authors： Lee SH,Park YK,Cho SM,Kang JK,Lee DJ

更新日期：2015-01-21 00:00:00

abstract：:Treatment of Helicobacter pylori (H. pylori) infection is paramount for the management of prevalent gastrointestinal disorders including peptic ulcer disease and gastric cancer. Due to the wide increase in prevalence of H. pylori resistance to antibiotics, clarithromycin-based triple therapies are not any more suitabl...

journal_title：World journal of gastroenterology

authors： Papastergiou V,Georgopoulos SD,Karatapanis S

更新日期：2014-08-07 00:00:00

abstract：AIM:To explore the role of mammalian target of rapamycin (mTOR) in the pathogenesis of cirrhotic cardiomyopathy and the potential of rapamycin to improve this pathologic condition. METHODS:Male albino Wistar rats weighing 100-120 g were treated with tetrachloride carbon (CCl4) for 8 wk to induce cirrhosis. Subsequentl...

journal_title：World journal of gastroenterology

authors： Saeedi Saravi SS,Ghazi-Khansari M,Ejtemaei Mehr S,Nobakht M,Mousavi SE,Dehpour AR

更新日期：2016-05-21 00:00:00

abstract：:Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though only on the basis of...

journal_title：World journal of gastroenterology

authors： Fedeli U,Girardi P,Mastrangelo G

更新日期：2019-09-07 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00

abstract：AIM:To assess the results of endoscopic mucosal resection with a ligation device (EMR-L) combined with three dimensional endoscopic ultrasonography (3D-EUS) using an ultrasonic probe for rectal carcinoids. In addition, diagnosis of the depth and size of lesions by EUS was evaluated. METHODS:Between January 2003 and Ma...

journal_title：World journal of gastroenterology

authors： Abe T,Kakemura T,Fujinuma S,Maetani I

更新日期：2008-07-07 00:00:00

abstract：AIM:To evaluate the role of mitochondrial microsatellite instability (mtMSI) in gastric carcinogenesis. METHODS:MtMSI was measured with PCR-single strand conformation polymorphism (PCR-SSCP) in 68 cases of advanced gastric cancer, 40 cases of chronic gastritis, 30 cases of intestinal metaplasia and 20 cases of dysplas...

journal_title：World journal of gastroenterology

authors： Ling XL,Fang DC,Wang RQ,Yang SM,Fang L

更新日期：2004-03-15 00:00:00

abstract：:Good preparation before endoscopic procedures is essential for successful visualization. The small bowel is difficult to evaluate because of its length and complex configuration. A meta-analysis was conducted of studies comparing small bowel visualization by capsule endoscopy with and without preparation. Medical data...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2008-03-07 00:00:00

abstract：:Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an...

journal_title：World journal of gastroenterology

authors： Haramura T,Haraguchi M,Irie J,Ito S,Tokai H,Noda K,Kitajima M,Minami S,Inoue K,Sasaki Y,Oshima K,Eguchi S

更新日期：2015-06-28 00:00:00

abstract：AIM:To prospectively investigate the detection rate of laterally spreading tumors (LSTs) of the colorectum by computed tomography (CT) colonography (CTC). METHODS:Patients with LSTs measuring ≥ 20 mm detected during colonoscopy were prospectively enrolled in the study. All patients underwent colonoscopy and subsequent...

journal_title：World journal of gastroenterology

authors： Togashi K,Utano K,Kijima S,Sato Y,Horie H,Sunada K,Lefor AT,Sugimoto H,Yasuda Y

更新日期：2014-12-14 00:00:00

abstract：:"Psychosocial stress" is an increasingly common concept in the challenging and highly-demanding modern society of today. Organic response to stress implicates two major components of the stress system, namely the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Stress is anamnestically reported ...

journal_title：World journal of gastroenterology

authors： Vere CC,Streba CT,Streba LM,Ionescu AG,Sima F

更新日期：2009-06-28 00:00:00

abstract：AIM:To analyze 67 cases of splenic abscess in a medical center of Taiwan during a period of 19 years. METHODS:From January 1986 to December 2004, a total of 67 patients with splenic abscess were enrolled for the retrospective study. The clinical characteristics, underlying diseases, organism spectra, therapeutic metho...

journal_title：World journal of gastroenterology

authors： Chang KC,Chuah SK,Changchien CS,Tsai TL,Lu SN,Chiu YC,Chen YS,Wang CC,Lin JW,Lee CM,Hu TH

更新日期：2006-01-21 00:00:00

abstract：:Multiple pathogenic mechanisms have been implicated in autoimmune hepatitis, but they have not fully explained susceptibility, triggering events, and maintenance or escalation of the disease. Furthermore, they have not identified a critical defect that can be targeted. The goals of this review are to examine the diver...

journal_title：World journal of gastroenterology

authors： Czaja AJ

更新日期：2019-12-07 00:00:00