Gastroenterology service in a teaching hospital in rural New Zealand, 1991-2003.

abstract：AIM:To investigate the fluid shear stress induced changes of (Ca(2+))i in neutrophils in pancreatic microcirculation of experimental acute pancreatitis (AP). METHODS:Wistar rats (n = 36) were randomized into three groups. A model of AP was established by subcutaneous injection of caerulein. Low-shear 30 viscometer was...

journal_title：World journal of gastroenterology

authors： Zhou ZG,Chen YQ,Liu XB,Hu WM,Tian BL,Chen HQ

更新日期：2004-11-01 00:00:00

abstract：AIM:To detect the expression of mitochondrial uncoupling protein 2 (UCP2) in colon cancer and analyze the relation between UCP2 expression and clinical pathological features of colon cancer. METHODS:Fifteen colon tissue samples and 15 its adjacent tissue samples were obtained from colon cancer patients during surgical...

journal_title：World journal of gastroenterology

authors： Kuai XY,Ji ZY,Zhang HJ

更新日期：2010-12-07 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：:Achalasia cardia is one of the common causes of motor dysphagia. Though the disease was first described more than 300 years ago, exact pathogenesis of this condition still remains enigmatic. Pathophysiologically, achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. In the...

journal_title：World journal of gastroenterology

authors： Ghoshal UC,Daschakraborty SB,Singh R

更新日期：2012-06-28 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：:The use of non-steroidal anti-inflammatory drugs (NSAIDs) is widespread worldwide thanks to their analgesic, anti-inflammatory and antipyretic effects. However, even more attention is placed upon the recurrence of digestive system complications in the course of their use. Recent data suggests that the complications of...

journal_title：World journal of gastroenterology

authors： Utzeri E,Usai P

更新日期：2017-06-14 00:00:00

abstract：:Pancreatic cancer is one of the deadliest cancers, ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment of metastatic pancreatic cancer (mPC) remains cytotoxic chemotherapy. In 2016, more than 40 years aft...

journal_title：World journal of gastroenterology

authors： Ghosn M,Ibrahim T,Assi T,El Rassy E,Kourie HR,Kattan J

更新日期：2016-12-14 00:00:00

abstract：AIM:To investigate the efficacy and side effects of the combined therapy of oxaliplatin and capecitabine in patients with metastatic esophageal squamous cell cancer (ESCC) and the survival of the patients. METHODS:Sixty-four patients (median age of 63 years) with histological or cytological confirmation of ESCC receiv...

journal_title：World journal of gastroenterology

authors： Qin TJ,An GL,Zhao XH,Tian F,Li XH,Lian JW,Pan BR,Gu SZ

更新日期：2009-02-21 00:00:00

abstract：AIM:To determine the association of circulating miR-125a/b expression with the risk and disease severity of Crohn's disease (CD), and with inflammatory cytokines. METHODS:Plasma samples were collected from patients with active CD (A-CD), or CD in remission (R-CD) and from healthy controls (HCs). The levels of the infl...

journal_title：World journal of gastroenterology

authors： Sun CM,Wu J,Zhang H,Shi G,Chen ZT

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is one of the leading causes of herb-induced liver injury in China. HLA-B*35:01 is reported to be a potential biomarker of Polygonum multiflorum-induced liver injury (PM-DILI). However, little is known about the relationship between single-nucleotide polymorphisms (SNPs) and PM-DILI. A...

journal_title：World journal of gastroenterology

authors： Yang WN,Pang LL,Zhou JY,Qiu YW,Miao L,Wang SY,Liu XZ,Tan KA,Shi WW,Wang GQ,Hou FQ

更新日期：2020-03-28 00:00:00

abstract：AIM:To discuss the use of mycophenolate mofetil (MMF) as an immunosuppressant in steroid resistant rejection after liver transplantation. METHODS:The clinical records of 260 adult patients who underwent living donor liver transplantation (LDLT) were reviewed. Tacrolimus and methylprednisolone were used for primary imm...

journal_title：World journal of gastroenterology

authors： Akamatsu N,Sugawara Y,Tamura S,Matsui Y,Kaneko J,Makuuchi M

更新日期：2006-08-14 00:00:00

abstract：:Cyclophosphamide is a potent cytotoxic agent used in many clinical settings. The main risks of cyclophosphamide therapy include hematological disorders, infertility, hemorrhagic cystitis and malignancies. Gastrointestinal side effects reported to date are often non-specific and not severe. We present the first case of...

journal_title：World journal of gastroenterology

authors： Yang LS,Cameron K,Papaluca T,Basnayake C,Jackett L,McKelvie P,Goodman D,Demediuk B,Bell SJ,Thompson AJ

更新日期：2016-10-21 00:00:00

abstract：AIM:To assess the efficacy and safety of combined directly acting antivirals (DAAs) for the treatment of Chinese chronic hepatitis C (CHC) patients in a real-world setting. METHODS:Hospitalized CHC patients who were treated with DAAs at Peking University First Hospital between January 2015 and December 2016 were enrol...

journal_title：World journal of gastroenterology

authors： Chen JH,Zeng Z,Zhang XX,Zhang Y,Zhang RW,Wang S,Wu CH,Yu M,Liu D,Xi HL,Zhou YX,An YY,Xu XY

更新日期：2017-06-14 00:00:00

abstract：:Mechanical lithotripsy (ML) is usually considered as a standard treatment option for large bile duct stones. However, it is impossible to retrieve oversized stones because the conventional lithotripsy basket may not be able to grasp the stone. However, there is no established endoscopic extraction method for such gian...

journal_title：World journal of gastroenterology

authors： Chung HJ,Jeong S,Lee DH,Lee JI,Lee JW,Bang BW,Kwon KS,Kim HK,Shin YW,Kim YS

更新日期：2012-07-07 00:00:00

abstract：AIM:To observe expression of CD14 protein and CD14 gene in rat liver sinusoidal endothelial cells (LSECs) during endotoxemia, and the role of CD14 protein in the activation of lipopolysaccharide (LPS)-induced LSECs. METHODS:Wistar rat endotoxemia model was established first by injection of a dose of LPS (5mg/kg, Esche...

journal_title：World journal of gastroenterology

authors： Gong JP,Dai LL,Liu CA,Wu CX,Shi YJ,Li SW,Li XH

更新日期：2002-06-01 00:00:00

abstract：AIM:To analyze the combined treatment of resection and intraoperative radiofrequency ablation (RFA) for multifocal hepatocellular carcinoma in terms of prognosis and surgical outcomes. METHODS:This study was a retrospective case comparison study using prospectively collected data. The study covered the period from Apr...

journal_title：World journal of gastroenterology

authors： Cheung TT,Ng KK,Chok KS,Chan SC,Poon RT,Lo CM,Fan ST

更新日期：2010-06-28 00:00:00

abstract：AIM:To establish novel intestinal myofibroblast (IMF) cell lines from mouse colonic mucosa and investigate their biological characters. METHODS:Primary IMFs were isolated from mucosal tissues of mouse colon that was denuded of epithelial cells and smooth muscle layer. For immortalization, primary IMFs were transfected...

journal_title：World journal of gastroenterology

authors： Kawasaki H,Ohama T,Hori M,Sato K

更新日期：2013-05-07 00:00:00

abstract：AIM:Inducible nitric oxide synthase (iNOS) plays a central role in the pathway of reactive oxygen and nitrogen species metabolism when Helicobacter pylori (H pylori) infection occurs in humans. iNOS Ser(608)Leu allele, a novel genetic polymorphism (C/T) occurring within exon 16 of the iNOS reductase domain, may have a ...

journal_title：World journal of gastroenterology

authors： Shen J,Wang RT,Wang LW,Xu YC,Wang XR

更新日期：2004-11-15 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：:Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, ra...

journal_title：World journal of gastroenterology

authors： Diefenbach KA,Breuer CK

更新日期：2006-05-28 00:00:00

abstract：AIM:To determine whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAIDs) prevent colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). METHODS:We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD relate...

journal_title：World journal of gastroenterology

authors： Burr NE,Hull MA,Subramanian V

更新日期：2016-04-07 00:00:00

abstract：AIM:To determine the precise incidence and clinical features of endoscopic ulcers following gastrectomy. METHODS:A consecutive series of patients who underwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ...

journal_title：World journal of gastroenterology

authors： Chung WC,Jeon EJ,Lee KM,Paik CN,Jung SH,Oh JH,Kim JH,Jun KH,Chin HM

更新日期：2012-07-07 00:00:00

abstract：AIM:To investigate a potential role of S100A4 in esophagus squamous cell carcinoma metastasis (ESCCs). METHODS:Expression of S100A4 and E-cadherin were analyzed in frozen sections from ESCCs (metastasis, n = 28; non-metastasis, n = 20) by reverse transcription-polymerase chain reaction, quantitative polymerase chain r...

journal_title：World journal of gastroenterology

authors： Chen D,Zheng XF,Yang ZY,Liu DX,Zhang GY,Jiao XL,Zhao H

更新日期：2012-03-07 00:00:00

abstract：:Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

journal_title：World journal of gastroenterology

authors： Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

更新日期：2014-07-07 00:00:00

abstract：AIM:To assess the safety and efficacy of antioxidant therapy for patients with chronic hepatitis C virus (HCV) infection. METHODS:One hundred chronic HCV infection patients failed in interferon treatment were enrolled and randomly assigned to receive combined intravenous and oral antioxidants or placebo, or oral treat...

journal_title：World journal of gastroenterology

authors： Gabbay E,Zigmond E,Pappo O,Hemed N,Rowe M,Zabrecky G,Cohen R,Ilan Y

更新日期：2007-10-28 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：AIM:To investigate the relationship of changes in expression of marker genes in functional categories or molecular networks comprising one functional category or multiple categories in progression of hepatic fibrosis in hepatitis C (HCV) patients. METHODS:Marker genes were initially identified using DNA microarray dat...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Zhang QW,Wagatsuma H,Mori M,Tamori A,Shiomi S,Nishiguchi S

更新日期：2008-04-07 00:00:00

abstract：AIM:To investigate Helicobacter pylori (H. pylori) eradication rates using second-line bismuth-containing quadruple therapy and to identify predictors of eradication failure. METHODS:This study included 636 patients who failed first-line triple therapy and received 7 d of bismuth-containing quadruple therapy between J...

journal_title：World journal of gastroenterology

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kim HK,Lee YD

更新日期：2017-02-14 00:00:00

abstract：AIM:To investigate the location alteration of Smad2 and Smad4 mRNAs in the liver during and after fibrogenesis in rats. METHODS:Eighty male Wistar rats weighing approximately 200 g each were used. The rat models of experimental hepatic fibrosis were established by injection with carbon tetrachloride (CCl4), normal rat...

journal_title：World journal of gastroenterology

authors： Liu Y,Wang LF,Zou HF,Song XY,Xu HF,Lin P,Zheng HH,Yu XG

更新日期：2006-03-14 00:00:00

abstract：:A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

journal_title：World journal of gastroenterology

authors： Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

更新日期：2008-10-21 00:00:00