Dilemma of first line regimens in metastatic pancreatic adenocarcinoma.

abstract：AIM:To evaluate the efficacy of sequential vs hybrid therapy in patients with Helicobacter pylori (H. pylori) infection. METHODS:From March 2013 to May 2014, one hundred and seventy-five H. pylori infected patients who had not been treated for H. pylori before were randomized to receive either sequential therapy (rabe...

journal_title：World journal of gastroenterology

authors： Chen KY,Lin TJ,Lin CL,Lee HC,Wang CK,Wu DC

更新日期：2015-09-28 00:00:00

abstract：AIM:To perform a meta-analysis of observational studies to further elucidate the relationship between oral bisphosphonate use and gastrointestinal cancer risk. METHODS:Systematic literature search was conducted in MEDLINE, EMBASE, and the Cochrane Library to identify studies through January 2011. Search terms were "bi...

journal_title：World journal of gastroenterology

authors： Oh YH,Yoon C,Park SM

更新日期：2012-10-28 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：:In this article, we have reviewed the hepatic perfusion disorder (HPD), etiopathogenesis of HPD and corresponding diseases. Review of the literature was based on computer searches (PubMed, Index Medicus) and personal experiences. We considered HPD reflects perfusion differences due to redistribution of arterial blood ...

journal_title：World journal of gastroenterology

authors： Tian JL,Zhang JS

更新日期：2006-05-28 00:00:00

abstract：AIM:Quasispecies of hepatitis C virus (HCV) are the foundation for rapid sequence evolution of HCV to evade immune surveillance of hosts. The consensus sequence evolution of a segment of HCV NS3 region, which encompasses putative cytotoxic T cell epitopes, was evaluated. METHODS:Three male patients, infected with HCV ...

journal_title：World journal of gastroenterology

authors： Guo HZ,Yin Y,Wang WL,Zhang CS,Wang T,Wang Z,Zhang J,Cheng H,Wang HT

更新日期：2004-03-15 00:00:00

abstract：AIM:To characterize the biochemical and immunological properties of an experimental ISCOMS vaccine prepared from a novel therapeutic polypeptide based on T cell epitopes of HBsAg, and a heptatis B-ISCOMS was prepared and investigated. METHODS:An immunostimulating complexes(ISCOMS)-based vaccine containing a novel ther...

journal_title：World journal of gastroenterology

authors： Guan XJ,Guan XJ,Wu YZ,Jia ZC,Shi TD,Tang Y

更新日期：2002-04-01 00:00:00

abstract：:More than 30 years after the discovery of human hepatitis B virus (HBV) this virus remains to be one of the major global health problems. In infected adolescents or adults, 5%-10% will lead to a chronic carrier state, whereas in infected neonates up to 90% develop chronicity. It is estimated that about 370 million peo...

journal_title：World journal of gastroenterology

authors： Glebe D

更新日期：2007-01-07 00:00:00

abstract：AIM:To establish whether there are fundamental differences in the biochemistries of adenocarcinomas of the gastroesophageal junction (GEJ) and the squamous cell carcinomas of the lower third of the esophagus (LTE). METHODS:Between February 1, 1997 and February 1, 2000, we obtained tissue samples at the moment of resec...

journal_title：World journal of gastroenterology

authors： Altorjay A,Paal B,Sohar N,Kiss J,Szanto I,Sohar I

更新日期：2005-10-07 00:00:00

abstract：AIM:To investigate the effect of a fat rich diet on non-steroidal anti-inflammatory drug (NSAID)-induced mucosal damage in the murine small intestine. METHODS:C57BL6 mice were fed 4 types of diets with or without indomethacin. One group was fed standard laboratory chow. The other groups were fed a fat diet consisting ...

journal_title：World journal of gastroenterology

authors： Ueda T,Hokari R,Higashiyama M,Yasutake Y,Maruta K,Kurihara C,Tomita K,Komoto S,Okada Y,Watanabe C,Usui S,Nagao S,Miura S

更新日期：2015-01-07 00:00:00

abstract：AIM:To evaluate the proinflammatory effects and molecular mechanisms of interleukin (IL)-17 in intestinal epithelial cell line HT-29. METHODS:HT-29 cells were cultured with IL-17, tumor necrosis factor (TNF)-α, or the combination of both IL-17 and TNF-α. Real-time PCR and Western blot were used to measure the gene exp...

journal_title：World journal of gastroenterology

authors： Wang YL,Fang M,Wang XM,Liu WY,Zheng YJ,Wu XB,Tao R

更新日期：2014-12-21 00:00:00

abstract：AIM:To investigate the reasons for the occurrence of the pink-color sign of iodine-unstained lesions. METHODS:In chromoendoscopy, the pink-color sign of iodine-unstained lesions is recognized as useful for the diagnosis of esophageal squamous cell carcinoma. Patients with superficial esophageal neoplasms treated by en...

journal_title：World journal of gastroenterology

authors： Ishihara R,Kanzaki H,Iishi H,Nagai K,Matsui F,Yamashina T,Matsuura N,Ito T,Fujii M,Yamamoto S,Hanaoka N,Takeuchi Y,Higashino K,Uedo N,Tatsuta M,Tomita Y,Ishiguro S

更新日期：2013-07-21 00:00:00

abstract：AIM:To investigate the hotspots, direction, and the time course of evolution of hepatitis A virus in the process of consecutive cell culture passage in human KMB17 diploid cells. METHODS:Wild type hepatitis A virus H2w was serially propagated in KMB17 cells until passage 30, and the full-length genomes of H2w and its ...

journal_title：World journal of gastroenterology

authors： Tang CH,Mao JS,Chai SA,Chen Y,Zhuang FC

更新日期：2007-09-14 00:00:00

abstract：:Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare, less than 1% of all pancreatic malignancies, and shows worse prognosis than that of invasive ductal adenocarcinoma of the pancreas. We present a case of en bloc resection for a huge undifferentiated carcinoma with OGCs tha...

journal_title：World journal of gastroenterology

authors： Jo S

更新日期：2014-03-14 00:00:00

abstract：:Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a...

journal_title：World journal of gastroenterology

authors： Danese S,Semeraro S,Papa A,Roberto I,Scaldaferri F,Fedeli G,Gasbarrini G,Gasbarrini A

更新日期：2005-12-14 00:00:00

abstract：AIM:To elucidate longitudinal changes of an endoscopic Barrett esophagus (BE), especially of short segment endoscopic BE (SSBE). METHODS:This study comprised 779 patients who underwent two or more endoscopies between January 2009 and December 2015. The intervals between the first and the last endoscopy were at least 6...

journal_title：World journal of gastroenterology

authors： Shimoyama S,Ogawa T,Toma T

更新日期：2016-09-21 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：AIM:To investigate Helicobacter pylori (H. pylori) eradication rates using second-line bismuth-containing quadruple therapy and to identify predictors of eradication failure. METHODS:This study included 636 patients who failed first-line triple therapy and received 7 d of bismuth-containing quadruple therapy between J...

journal_title：World journal of gastroenterology

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kim HK,Lee YD

更新日期：2017-02-14 00:00:00

abstract：:Hepatitis C virus (HCV) is one of the main etiological factors responsible for liver disease worldwide. It has been estimated that there are over 170 million people infected with HCV worldwide. Of these infected individuals, approximately 75% will go on to develop a life long necroinflammatory liver disease, which ove...

journal_title：World journal of gastroenterology

authors： McCartney EM,Beard MR

更新日期：2010-03-21 00:00:00

abstract：AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specific to 16S rRNA of Helicobacter spp. was performed on paraffin-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The sample...

journal_title：World journal of gastroenterology

authors： Karagin PH,Stenram U,Wadström T,Ljungh A

更新日期：2010-10-14 00:00:00

abstract：AIM:To evaluate the efficacy of short-term overlap lamivudine therapy with adefovir in patients with lamivudine-resistant and naive chronic hepatitis B, we compared patients receiving overlap therapy with those receiving adefovir alone. METHODS:Eighty patients who had received lamivudine treatment for various periods ...

journal_title：World journal of gastroenterology

authors： Nam SW,Bae SH,Lee SW,Kim YS,Kang SB,Choi JY,Cho SH,Yoon SK,Han JY,Yang JM,Lee YS

更新日期：2008-03-21 00:00:00

abstract：AIM:To evaluate the role of RARalpha gene in mediating the growth inhibitory effect of all-trans retinoic acid (ATRA) on gastric cancer cells. METHODS:The expression levels of retinoic acid receptors (RARs) in gastric cancer cells were detected by Northern blot. Transient transfection and chlorophenicol acetyl transfe...

journal_title：World journal of gastroenterology

authors： Liu S,Wu Q,Chen ZM,Su WJ

更新日期：2001-10-01 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：:Despite that some approved drugs and genetically engineered vaccines against hepatitis B virus (HBV) are available for HBV patients, HBV infection is still a severe public health problem in the world. All the approved therapeutic drugs (including interferon-alpha and nucleoside analogues) have their limitations. No dr...

journal_title：World journal of gastroenterology

authors： Wu YH

更新日期：2016-01-07 00:00:00

abstract：AIM:To meta-analyse the European abstracts presented between 1997-2004 at the European H pylori Study Group, United European Gastroenterology Week meetings and World Congresses of Gastroenterology. METHODS:The abstracts of randomized/controlled prospective studies were classified into groups based on first-line eradic...

journal_title：World journal of gastroenterology

authors： Buzás GM,Józan J

更新日期：2006-09-07 00:00:00

abstract：AIM:Overexpression of tumor protein p53-induced nuclear protein 1 (TP53INP1) induces G1 cell cycle arrest and increases p53-mediated apoptosis. To clarify the clinical importance of TP53INP1, we analyzed TP53INP1 and p53 expression in gastric cancer. METHODS:TP53INP1 and p53 expression were examined using immunohistoc...

journal_title：World journal of gastroenterology

authors： Jiang PH,Motoo Y,Garcia S,Iovanna JL,Pébusque MJ,Sawabu N

更新日期：2006-02-07 00:00:00

abstract：AIM:To determine the expression characteristics of connective tissue growth factor (CTGF/CCN2) in human hepatocellular carcinoma (HCC) in histology and to elucidate the roles of CCN2 on hepatoma cell cycle progression and metastasis in vitro. METHODS:Liver samples from 36 patients (who underwent hepatic resection for ...

journal_title：World journal of gastroenterology

authors： Xiu M,Liu YH,Brigstock DR,He FH,Zhang RJ,Gao RP

更新日期：2012-12-21 00:00:00

abstract：:In 2008, the European Association for the study of the liver (EASL) defined occult hepatitis B virus infection (OBI) as the "presence of hepatitis B virus (HBV) DNA in the liver (with detectable or undetectable HBV DNA in the serum) of individuals testing hepatitis B surface antigen (HBsAg) negative by currently avail...

journal_title：World journal of gastroenterology

authors： Ocana S,Casas ML,Buhigas I,Lledo JL

更新日期：2011-03-28 00:00:00

abstract：AIM:To compare therapeutic outcomes and adverse events in initial solitary hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA) and CyberKnife(®). METHODS:Seventy three consecutive patients with initial solitary HCC treated with RFA (38 patients; RFA group) and CyberKnife(®) (35 patients; CK group...

journal_title：World journal of gastroenterology

authors： Shiozawa K,Watanabe M,Ikehara T,Matsukiyo Y,Kogame M,Kishimoto Y,Okubo Y,Makino H,Tsukamoto N,Igarashi Y,Sumino Y

更新日期：2015-12-28 00:00:00

abstract：AIM:To explore the diffusion gradient b-factor that optimizes both apparent diffusion coefficient (ADC) measurement and contrast-to-noise (CNR) for assessing tumor response to transarterial chemoembolization (TACE) in a rabbit model. METHODS:Twelve New Zealand white rabbits bearing VX2 tumors in the liver were treated...

journal_title：World journal of gastroenterology

authors： Jiang ZX,Peng WJ,Li WT,Tang F,Liu SY,Qu XD,Wang JH,Lu HF

更新日期：2008-10-14 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00