Abstract:
AIM:To determine the upper cut-off values of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in a Northern Chinese population. METHODS:A total of 3769 subjects in Jilin Province Northeast China were stratified to determine the potential factors affecting serum ALT and AST levels. The upper cut-off values of serum ALT and AST in these subjects were determined using receiver operating characteristic analysis and their sensitivity and specificity were evaluated. RESULTS:Stratification analysis revealed that serum ALT and AST levels were associated with gender, alcohol consumption, serum cholesterol and triglyceride levels, and body mass index. The upper cut-off values of serum ALT and AST were 22.15 U/L and 25.35 U/L for healthy men and 22.40 U/L and 24.25 U/L for healthy women, respectively. The new cut-off values had a higher sensitivity, but a slightly lower specificity than the current standards. CONCLUSION:Our results indicate that the new upper cut-off values of serum ALT and AST are markedly lower than current standards and may be valuable for the evaluation of liver function.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Zhang P,Wang CY,Li YX,Pan Y,Niu JQ,He SMdoi
10.3748/wjg.v21.i8.2419subject
Has Abstractpub_date
2015-02-28 00:00:00pages
2419-24issue
8eissn
1007-9327issn
2219-2840journal_volume
21pub_type
杂志文章abstract:AIM:To investigate the effect of Clostridium difficile (C. difficile) infection in an interleukin 10-deficient (IL-10(-/-)) mouse model of inflammatory bowel disease. METHODS:Bone marrow-derived dendritic cells isolated from wild type (WT) and IL-10(-/-)mice were stimulated for 4 h with C. difficile toxin A (200 μg/mL...
journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v20.i45.17084
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.3748/wjg.v21.i32.9526
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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pub_type: 评论,信件
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更新日期:2017-08-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:World journal of gastroenterology
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v24.i14.1521
更新日期:2018-04-14 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-05-14 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v19.i47.9127
更新日期:2013-12-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v8.i5.956
更新日期:2002-10-01 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v11.i22.3363
更新日期:2005-06-14 00:00:00
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pub_type: 杂志文章
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pub_type: 社论,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 社论
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更新日期:2017-05-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v22.i4.1411
更新日期:2016-01-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,meta分析
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更新日期:2019-09-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v4.i2.147
更新日期:1998-04-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v12.i14.2291
更新日期:2006-04-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2017-02-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2011-04-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2012-10-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v20.i30.10338
更新日期:2014-08-14 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-12-21 00:00:00