Primary hepatic choriocarcinoma in a 49-year-old man: report of a case.

Abstract:

:We report a case of hepatic choriocarcinoma in a man diagnosed at autopsy after a rapid downhill clinical course. The patient was a 49-year-old man who presented with acute right-sided abdominal pain. There were no masses palpable on physical examination. Radiographic findings showed large multi-nodular tumors mainly in the right lobe of the liver. Fludeoxyglucose-positron emission tomography scan showed uptake only in the liver, and no uptake in the testes. We initially planned to perform a liver resection for the presumed diagnosis of intra-hepatic cholangiocarcinoma. However, the tumors grew rapidly and ruptured. Multiple lung metastases rapidly developed resulting in respiratory failure, preventing liver resection or even biopsy. He died 60 d after initial presentation with no pathological diagnosis. Postmortem studies included histopathological and immunohistological examinations which diagnosed a primary choriocarcinoma of the liver. Primary hepatic choriocarcinoma is very rare but should be considered in the differential diagnosis of a liver tumor in a middle aged man. Establishing this diagnosis may enable treatment of the choriocarcinoma. Liver biopsy and evaluation of serum human chorionic gonadotropin are recommended in these patients.

journal_name

World J Gastroenterol

authors

Sekine R,Hyodo M,Kojima M,Meguro Y,Suzuki A,Yokoyama T,Lefor AT,Hirota N

doi

10.3748/wjg.v19.i48.9485

subject

Has Abstract

pub_date

2013-12-28 00:00:00

pages

9485-9

issue

48

eissn

1007-9327

issn

2219-2840

journal_volume

19

pub_type

杂志文章
  • Mucosa repair mechanisms of Tong-Xie-Yao-Fang mediated by CRH-R2 in murine, dextran sulfate sodium-induced colitis.

    abstract:AIM:To explore the significance of corticotropin-releasing hormone (CRH)-receptor (R)2 in mucosal healing of dextran sulfate sodium (DSS)-induced colitis and the effect of Tong-Xie-Yao-Fang (TXYF) on CRH-R2 expression and regulation. METHODS:Ulcerative colitis was induced in mice by administration of 3% (w/v) DSS for ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i16.1766

    authors: Gong SS,Fan YH,Wang SY,Han QQ,Lv B,Xu Y,Chen X,He YE

    更新日期:2018-04-28 00:00:00

  • Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats.

    abstract:AIM:To study the inhibitory effect of mononuclear bone marrow cell (BMC) transplantation on carbon tetrachloride (CCl(4)) -induced liver fibrosis in rats. METHODS:Rat liver fibrosis models were induced by CCl(4) and alcohol administration. After 8 wk, twenty rats were randomly allocated into treatment group (n = 10) a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i12.1851

    authors: Cao BQ,Lin JZ,Zhong YS,Huang SB,Lin N,Tang ZF,Chen R,Xiang P,Xu RY

    更新日期:2007-03-28 00:00:00

  • Iatrogenic bile duct injuries: etiology, diagnosis and management.

    abstract::Iatrogenic bile duct injuries (IBDI) remain an important problem in gastrointestinal surgery. They are most frequently caused by laparoscopic cholecystectomy which is one of the commonest surgical procedures in the world. The early and proper diagnosis of IBDI is very important for surgeons and gastroenterologists, be...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.15.4097

    authors: Jabłońska B,Lampe P

    更新日期:2009-09-07 00:00:00

  • Gastric intramural hematoma accompanied by severe epigastric pain and hematemesis after endoscopic mucosal resection.

    abstract::Gastric intramural hematoma is a rare injury of the stomach, and is most often seen in patients with underlying disease. Such injury following endoscopic therapy is even rarer, and there are no universally accepted guidelines for its treatment. In this case report, we describe a gastric intramural hematoma which occur...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i47.7127

    authors: Sun P,Tan SY,Liao GH

    更新日期:2012-12-21 00:00:00

  • Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients.

    abstract::Although gastroduodenal ulcers are common in solid organ transplant patients, there are few reports on multiple giant ulcers in the distal ileum and ileocecal valve caused by immunosuppressants Herein, we report on a liver transplant recipient and a renal transplant recipient with multiple large ulcers in the distal i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i24.5616

    authors: Guo YW,Gu HY,Abassa KK,Lin XY,Wei XQ

    更新日期:2016-06-28 00:00:00

  • Avidin chase reduces side effects of radioimmunotherapy in nude mice bearing human colon carcinoma.

    abstract:AIM:To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome. METHODS:Purified anti-CEA monoclonal antibody (McAb) was biotinylated with NHS-biotin, and then radiolabeled with 188Re by the direct method. 188Re-labeled b...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i13.1917

    authors: Li GP,Wang YX,Huang K,Zhang H,Zhang CF

    更新日期:2005-04-07 00:00:00

  • Fenofibrate for patients with asymptomatic primary biliary cirrhosis.

    abstract:AIM:Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation. Ursodeoxycholic acid (UDCA) is now used as a first-line drug for asymptomatic PBC (aPBC) because it is reported that UDCA decrea...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i6.894

    authors: Dohmen K,Mizuta T,Nakamuta M,Shimohashi N,Ishibashi H,Yamamoto K

    更新日期:2004-03-15 00:00:00

  • Body mass index is associated with age-at-onset of HCV-infected hepatocellular carcinoma patients.

    abstract:AIM:To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS:Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-naïve HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i7.914

    authors: Akiyama T,Mizuta T,Kawazoe S,Eguchi Y,Kawaguchi Y,Takahashi H,Ozaki I,Fujimoto K

    更新日期:2011-02-21 00:00:00

  • Pancreatic biomarkers: could they be the answer?

    abstract::Pancreatic ductal adenocarcinoma (PDA) is known for its poor prognosis. Most of the patients are diagnosed with advanced stages, when no curative treatment is available. Currently, despite extensive clinical research on PDA, the median overall survival remains short. Diagnosis delay and primary chemo-resistance due to...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i24.7819

    authors: Lamarca A,Feliu J

    更新日期:2014-06-28 00:00:00

  • Nonalcoholic fatty liver disease as a multi-systemic disease.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i16.4079

    authors: Fotbolcu H,Zorlu E

    更新日期:2016-04-28 00:00:00

  • miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer.

    abstract:AIM:To examine the role of microRNA 1181 (miR-1181) in invasion and proliferation in pancreatic cancer. METHODS:We analyzed the expression of miR-1181 in several pancreatic cancer cell lines and generated stable MIA-PaCa-2 and PANC-1 cell lines with up-regulated miR-1181 expression using an adenovirus delivery system....

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i9.1594

    authors: Wang J,Guo XJ,Ding YM,Jiang JX

    更新日期:2017-03-07 00:00:00

  • Relationship between methylation and colonic inflammation in inflammatory bowel disease.

    abstract:AIM:To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients. METHODS:We evaluated the methylation status of 2 genes (SLIT2 and TGFB2) in 226 biopsies taken from 62 colonoscopies of 38 patients (29 ulcerative colitis...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i30.10591

    authors: Lobatón T,Azuara D,Rodríguez-Moranta F,Loayza C,Sanjuan X,de Oca J,Fernández-Robles A,Guardiola J,Capellá G

    更新日期:2014-08-14 00:00:00

  • Intrahepatic and peripheral T-cell responses in genotype 1b hepatitis C virus-infected patients with persistently normal and elevated aminotransferase levels.

    abstract:AIM:To evaluate whether the cytokine responses in liver and serum differ in chronic hepatitis C patients with normal and high alanine aminotransferase (ALT) levels. METHODS:Thirty-three (16 with normal ALT level as group 1 and 17 with elevated ALT level as group 2) patients infected with genotype 1b hepatitis C virus ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i45.7188

    authors: Akyüz F,Polat N,Kaymakoglu S,Aksoy N,Demir K,Beşişik F,Badur S,Cakaloglu Y,Okten A

    更新日期:2005-12-07 00:00:00

  • Diet and microbiota in inflammatory bowel disease: The gut in disharmony.

    abstract::Bacterial colonization of the gut shapes both the local and the systemic immune response and is implicated in the modulation of immunity in both healthy and disease states. Recently, quantitative and qualitative changes in the composition of the gut microbiota have been detected in Crohn's disease and ulcerative colit...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v23.i12.2124

    authors: Rapozo DC,Bernardazzi C,de Souza HS

    更新日期:2017-03-28 00:00:00

  • Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy.

    abstract::It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i28.3895

    authors: Lee H,Son HJ,Rhee PL,Kim JJ,Rhee JC

    更新日期:2007-07-28 00:00:00

  • Investigation of HGV and TTV infection in sera and saliva from non-hepatitis patients with oral diseases.

    abstract:AIM:To determine the frequencies of HGV and TTV infections in serum and saliva samples of non-hepatitis patients with oral diseases in Hangzhou area, and to understand the correlation between detected results of HGV RNA and/or TTV DNA in sera and in saliva from the same patients. METHODS:RT-nested PCR for HGV RNA dete...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i5.857

    authors: Yan J,Chen LL,Lou YL,Zhong XZ

    更新日期:2002-10-01 00:00:00

  • Current understanding concerning intestinal stem cells.

    abstract::In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i31.7099

    authors: Cui S,Chang PY

    更新日期:2016-08-21 00:00:00

  • ADAM17 mRNA expression and pathological features of hepatocellular carcinoma.

    abstract:AIM:To study the expression of a disintegrin and metalloproteinase 17 (ADAM17) mRNA in hepatocellular carcinoma (HCC) and to evaluate the relationship between ADAM17 mRNA expression and clinicopathological features of HCC. METHODS:Hepatocellular carcinomas (HCC) from 31 cases were divided into small HCC (SHCC), nodula...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i18.2735

    authors: Ding X,Yang LY,Huang GW,Wang W,Lu WQ

    更新日期:2004-09-15 00:00:00

  • A newly designed big cup nitinol stent for gastric outlet obstruction.

    abstract:AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i33.4206

    authors: Shi D,Liao SH,Geng JP

    更新日期:2010-09-07 00:00:00

  • Hexahydrocurcumin enhances inhibitory effect of 5-fluorouracil on HT-29 human colon cancer cells.

    abstract:AIM:To investigate the ability of hexahydrocurcumin (HHC) to enhance 5-fluorouracil (5-FU) in inhibiting the growth of HT-29 cells by focusing on cyclooxygenase (COX)-2 expression. METHODS:Antiproliferative effects of HHC and 5-FU, alone and in combination, on growth of HT-29 human colon cancer cells were assessed usi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i19.2383

    authors: Srimuangwong K,Tocharus C,Yoysungnoen Chintana P,Suksamrarn A,Tocharus J

    更新日期:2012-05-21 00:00:00

  • Comparison of four models for end-stage liver disease in evaluating the prognosis of cirrhosis.

    abstract:AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6546

    authors: Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

    更新日期:2008-11-14 00:00:00

  • Altered distribution of regulatory lymphocytes by oral administration of soy-extracts exerts a hepatoprotective effect alleviating immune mediated liver injury, non-alcoholic steatohepatitis and insulin resistance.

    abstract:AIM:To determine the immune-modulatory and the hepatoprotective effects of oral administration of two soy extracts in immune mediated liver injury and non-alcoholic steatohepatitis (NASH). METHODS:Two soy extracts, M1 and OS, were orally administered to mice with concanavalin A (ConA) immune-mediated hepatitis, to hig...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i24.7443

    authors: Khoury T,Ben Ya'acov A,Shabat Y,Zolotarovya L,Snir R,Ilan Y

    更新日期:2015-06-28 00:00:00

  • Science of weight loss supplements: compromised by conflicts of interest?

    abstract::Weight loss supplements often contain powerful pharmacoactive ingredients with the potential to cause harm. Trials used to determine product safety and effectiveness, meanwhile, tend to be small, of short duration, and frequently lack financial conflict of interest disclosures. These factors could conspire to place co...

    journal_title:World journal of gastroenterology

    pub_type: 评论,信件

    doi:10.3748/wjg.v16.i38.4880

    authors: Lobb A

    更新日期:2010-10-14 00:00:00

  • Pancreatic guidewire placement for achieving selective biliary cannulation during endoscopic retrograde cholangio-pancreatography.

    abstract:AIM:To investigate the frequency and risk factors for acute pancreatitis after pancreatic guidewire placement (P-GW) in achieving cannulation of the bile duct during endoscopic retrograde cholangio-pancreatography (ERCP). METHODS:P-GW was performed in 113 patients in whom cannulation of the bile duct was difficult. Th...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.5595

    authors: Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y

    更新日期:2008-09-28 00:00:00

  • Possible contribution of artificial neural networks and linear discriminant analysis in recognition of patients with suspected atrophic body gastritis.

    abstract:AIM:To investigate whether ANNs and LDA could recognize patients with ABG in a database, containing only clinical and biochemical variables, of a pool of patients with and without ABG, by selecting the most predictive variables and by reducing input data to the minimum. METHODS:Data was collected from 350 consecutive ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i37.5867

    authors: Lahner E,Grossi E,Intraligi M,Buscema M,Corleto VD,Delle Fave G,Annibale B

    更新日期:2005-10-07 00:00:00

  • Tumor necrosis factor-α inhibitors and chronic hepatitis C: a comprehensive literature review.

    abstract::Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i44.7867

    authors: Pompili M,Biolato M,Miele L,Grieco A

    更新日期:2013-11-28 00:00:00

  • Intermediate-advanced hepatocellular carcinoma in Argentina: Treatment and survival analysis.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) represents the sixteenth most frequent cancer in Argentina. The rise of new therapeutic modalities in intermediate-advanced HCC opens up a new paradigm for the treatment of HCC. AIM:To describe real-life treatments performed in patients with intermediate-advanced HCC before th...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v25.i27.3607

    authors: Piñero F,Marciano S,Fernández N,Silva J,Anders M,Zerega A,Ridruejo E,Romero G,Ameigeiras B,D'Amico C,Gaite L,Bermúdez C,Reggiardo V,Colombato L,Gadano A,Silva M

    更新日期:2019-07-21 00:00:00

  • Effectiveness of exercise in hepatic fat mobilization in non-alcoholic fatty liver disease: Systematic review.

    abstract:AIM:To investigate the efficacy of exercise interventions on hepatic fat mobilization in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:Ovid-Medline, PubMed, EMBASE and Cochrane database were searched for randomized trials and prospective cohort studies in adults aged ≥ 18 which investigated the effects o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i27.6318

    authors: Golabi P,Locklear CT,Austin P,Afdhal S,Byrns M,Gerber L,Younossi ZM

    更新日期:2016-07-21 00:00:00

  • Is interferon-beta an alternative treatment for chronic hepatitis C?

    abstract::The treatment of chronic hepatitis C (CHC) is still far from optimal, particularly for those subpopulations that do not respond to the standard combination therapy with Interferon-alpha (IFNalpha) plus ribavirin. Although in some cases the use of higher doses or longer treatment periods may be effective, these approac...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i17.2730

    authors: Moreno-Otero R,Trapero-Marugán M,Gómez-Domínguez E,García-Buey L,Moreno-Monteagudo JA

    更新日期:2006-05-07 00:00:00

  • Endoscopic ultrasound-guided biliary drainage: Bilateral systems drainage via left duct approach.

    abstract::Endoscopic ultrasound (EUS)-guided biliary drainage is accepted as a less invasive, alternative treatment for patients in whom endoscopic retrograde cholangiopancreatography has failed. Most patients with malignant hilar obstruction undergo EUS-guided hepaticogastrostomy. The authors present the case of a 77-year-old ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i34.10045

    authors: Prachayakul V,Aswakul P

    更新日期:2015-09-14 00:00:00