Intrahepatic and peripheral T-cell responses in genotype 1b hepatitis C virus-infected patients with persistently normal and elevated aminotransferase levels.

abstract：AIM:To investigate the expression of three types of mucin (MUC1, MUC2, MUC5AC) and E-cadherin in human gastric carcinomas and their clinical significance. METHODS:Ninety-four gastric cancer specimens were classified according to WHO criteria and detected by immunohistochemical assay of expression of mucins and E-cadhe...

journal_title：World journal of gastroenterology

authors： Zhang HK,Zhang QM,Zhao TH,Li YY,Yi YF

更新日期：2004-10-15 00:00:00

abstract：:Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

journal_title：World journal of gastroenterology

authors： Rustagi T,Mashimo H

更新日期：2011-11-07 00:00:00

abstract：AIM:To identify the differentially over-expressed genes associated with β-catenin accumulation in nuclei of hepatocellular carcinoma (HCC) cells. METHODS:Differentially expressed genes were identified in radiation-induced B6C3 F1 mouse HCC cells by mRNA differential display, Northern blot and RT-PCR, respectively. Tot...

journal_title：World journal of gastroenterology

authors： Li YS,Liu M,Nakata Y,Tang HB

更新日期：2011-04-07 00:00:00

abstract：AIM:Heat shock protein (HSP)70 is over-expressed in human gastric cancer and plays an important role in the progression of this cancer. We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer. METHODS:Human gastric cance...

journal_title：World journal of gastroenterology

authors： Zhao ZG,Shen WL

更新日期：2005-01-07 00:00:00

abstract：AIM:To study the blood-brain barrier integrity, brain edema, animal behavior and ammonia plasma levels in prehepatic portal hypertensive rats with and without acute liver intoxication. METHODS:Adults male Wistar rats were divided into four groups. Group I: sham operation; II: Prehepatic portal hypertension, produced b...

journal_title：World journal of gastroenterology

authors： Scorticati C,Prestifilippo JP,Eizayaga FX,Castro JL,Romay S,Fernández MA,Lemberg A,Perazzo JC

更新日期：2004-05-01 00:00:00

abstract：AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

journal_title：World journal of gastroenterology

authors： Yang LJ,Wang WL

更新日期：2002-10-01 00:00:00

abstract：:A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred, but it spontaneously improved...

journal_title：World journal of gastroenterology

authors： Uesato M,Kono T,Akutsu Y,Murakami K,Kagaya A,Muto Y,Nakano A,Aikawa M,Tamachi T,Amagai H,Arasawa T,Muto Y,Matsubara H

更新日期：2017-07-28 00:00:00

abstract：:Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with...

journal_title：World journal of gastroenterology

authors： Inchingolo R,Posa A,Mariappan M,Spiliopoulos S

更新日期：2019-08-28 00:00:00

abstract：AIM:To investigate Fusobacterium nucleatum (F. nucleatum) abundance in colorectal cancer (CRC) tissues and its association with CRC invasiveness in Chinese patients. METHODS:The resected cancer and adjacent normal tissues (10 cm beyond cancer margins) from 101 consecutive patients with CRC were collected. Fluorescent ...

journal_title：World journal of gastroenterology

authors： Li YY,Ge QX,Cao J,Zhou YJ,Du YL,Shen B,Wan YJ,Nie YQ

更新日期：2016-03-21 00:00:00

abstract：AIM:To observe the kinetics of D (-)-lactate alteration in both portal and systemic circulation systems, and its relationship with intestinal injury in rats subjected to acute intestinal ischemia-reperfusion. METHODS:Anesthetized rats underwent a 75-min superior mesenteric artery occlusion followed by a 6-h reperfusio...

journal_title：World journal of gastroenterology

authors： Yao YM,Yu Y,Wu Y,Lu LR,Sheng ZY

更新日期：1997-12-15 00:00:00

abstract：:A Killian-Jamieson diverticulum (KJD) is an unfamiliar and rare cervical esophageal diverticulum. This diverticulum originates on the anterolateral wall of the proximal cervical esophagus through a muscular gap (the Killian-Jamieson space) below the cricopharyngeal muscle and lateral to the longitudinal muscle of the ...

journal_title：World journal of gastroenterology

authors： Lee CK,Chung IK,Park JY,Lee TH,Lee SH,Park SH,Kim HS,Kim SJ

更新日期：2008-11-14 00:00:00

abstract：AIM:To investigate the seroprevalence and molecular characteristics of hepatitis E virus (HEV) in the illegal blood donors (IBDs) of central China in the early 1990s. METHODS:A total of 546 blood samples were collected from the IBDs in Maanshan city, a questionnaire was completed by each subject, detailing the age, se...

journal_title：World journal of gastroenterology

authors： Cheng XF,Wen YF,Zhu M,Zhan SW,Zheng JX,Dong C,Xiang KX,Xia XB,Wang G,Han LF

更新日期：2012-03-07 00:00:00

abstract：:Complete response to chemoradiotherapy for rectal cancer is becoming a common clinical entity. Techniques to diagnose complete response and how to survey these patients without operative intervention are still unclear. We review the most recent evidence. Barriers to firm conclusions regarding this are heterogeneity of...

journal_title：World journal of gastroenterology

authors： Couch DG,Hemingway DM

更新日期：2016-01-14 00:00:00

abstract：AIM:To compare prevalence rates of non-alcoholic fatty liver disease (NAFLD) between Hispanics of Mexican origin and Hispanics of Dominican and Puerto Rican origin. METHODS:We evaluated prevalence rates of NAFLD between the two largest sub-populations of Hispanics in the United States; Hispanics of Mexican origin and ...

journal_title：World journal of gastroenterology

authors： Fleischman MW,Budoff M,Zeb I,Li D,Foster T

更新日期：2014-05-07 00:00:00

abstract：AIM:To investigate the effects of entero-hepatic bile acid circulation on the inter-digestive migrating myoelectrical complex (MMC) in rats. METHODS:Thirty-two rats were divided into four groups. Three pairs of bipolar silver electrodes were chronically implanted in the antrum, duodenum and jejunum. Three groups of th...

journal_title：World journal of gastroenterology

authors： Fang P,Dong L,Zhang WJ,Luo JY

更新日期：2005-09-14 00:00:00

abstract：:The diagnosis of herbal hepatotoxicity or herb induced liver injury (HILI) represents a particular clinical and regulatory challenge with major pitfalls for the causality evaluation. At the day HILI is suspected in a patient, physicians should start assessing the quality of the used herbal product, optimizing the clin...

journal_title：World journal of gastroenterology

authors： Teschke R,Frenzel C,Schulze J,Eickhoff A

更新日期：2013-05-21 00:00:00

abstract：AIM:To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS:Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 ...

journal_title：World journal of gastroenterology

authors： Abd El-Haleim EA,Bahgat AK,Saleh S

更新日期：2016-03-14 00:00:00

abstract：AIM:To investigate the mechanisms of chloride intracellular channel 1 (CLIC1) in the metastasis of colon cancer under hypoxia-reoxygenation (H-R) conditions. METHODS:Fluorescent probes were used to detect reactive oxygen species (ROS) in LOVO cells. Wound healing assay and transwell assay were performed to examine the...

journal_title：World journal of gastroenterology

authors： Wang P,Zeng Y,Liu T,Zhang C,Yu PW,Hao YX,Luo HX,Liu G

更新日期：2014-02-28 00:00:00

abstract：AIM:To investigate the allelic and haplotypic association of reg1alpha gene with tropical calcific pancreatitis (TCP). Since TCP is known to have a variable genetic basis, we investigated the interaction between mutations in the susceptibility genes, SPINK1 and CTSB with reg1alpha polymorphisms. METHODS:We analyzed th...

journal_title：World journal of gastroenterology

authors： Mahurkar S,Bhaskar S,Reddy DN,Rao GV,Chandak GR

更新日期：2007-11-28 00:00:00

abstract：:We report a case of a 32-year-old woman with episodic right lower quadrant abdominal pain. With the diagnosis of either acute appendicitis or tubo-ovarian abscess, she was treated with antibiotics, which successfully relieved the pain and the inflammatory findings. She repeated the clinical condition a few times and a...

journal_title：World journal of gastroenterology

authors： Niwa H,Hiramatsu T

更新日期：2008-02-28 00:00:00

abstract：AIM:To assess whether trace metal concentrations (which influence metabolism as both essential and non-essential elements) are increased or decreased in cancerous tissues and to understand the precise role of these metals in carcinogenesis. METHODS:Concentrations of trace metals including Cd, Ni, Cu, Zn, Fe, Mg and Ca...

journal_title：World journal of gastroenterology

authors： Yaman M,Kaya G,Yekeler H

更新日期：2007-01-28 00:00:00

abstract：AIM:To evaluate the utility of local tumor therapy combined with percutaneous transhepatic biliary drainage (PTBD) for malignant obstructive biliary disease. METHODS:A total of 233 patients with malignant biliary obstruction were treated in our hospital with PTBD by placement of metallic stents and/or plastic tubes. A...

journal_title：World journal of gastroenterology

authors： Qian XJ,Zhai RY,Dai DK,Yu P,Gao L

更新日期：2006-01-14 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the distribution of neutrophils in the tumor microenvironment with the prognosis of cholangiocarcinoma. METHODS:Two hundred and fifty-four formalin-fixed and paraffin embedded tissue blocks were analyzed, including tissues from cholangiocarcinoma (n =...

journal_title：World journal of gastroenterology

authors： Mao ZY,Zhu GQ,Xiong M,Ren L,Bai L

更新日期：2015-04-28 00:00:00

abstract：:Transjugular intrahepatic portosystemic shunt (TIPSS) is considered a valid therapeutic option for the treatment of portal hypertension and its complications. The guidelines for this procedure have already been established on the basis of the normal vascular anatomy and of various technical radiological aspects. In so...

journal_title：World journal of gastroenterology

authors： Petridis I,Miraglia R,Marrone G,Gruttadauria S,Luca A,Vizzini GB,Gridelli B

更新日期：2010-03-07 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：AIM:To investigate the effect of pituitary homeobox 1 (PITX1) expression in cases of human gastric cancer on cancer differentiation and progression, and carcinogenesis. METHODS:Using polyclonal PITX1 antibodies, we studied the expression of PITX1 in normal gastric mucosa, atypical hyperplasia, intestinal metaplasia, a...

journal_title：World journal of gastroenterology

authors： Chen YN,Chen H,Xu Y,Zhang X,Luo Y

更新日期：2008-01-14 00:00:00

abstract：AIM:Over 90% of drugs are metabolized by the cytochrome P-450 (CYP) family of liver isoenzymes. The most important enzymes are CYP1A2, 3A4, 2C9/19, 2D6 and 2E1. Although CYP2D6 accounts for <2% of the total CYP liver enzyme content, it mediates metabolism in almost 25% of drugs. In order to study its enzymatic activity...

journal_title：World journal of gastroenterology

authors： Zhuge J,Yu YN,Wu XD

更新日期：2004-01-15 00:00:00

abstract：:Acute pancreatitis is an inflammatory disorder of the pancreas that may cause life-threatening complications. Etiologies of pancreatitis vary, with gallstones accounting for the majority of all cases, followed by alcohol. Other causes of pancreatitis include trauma, ischemia, mechanical obstruction, infections, autoim...

journal_title：World journal of gastroenterology

authors： Binker MG,Cosen-Binker LI

更新日期：2014-05-21 00:00:00

abstract：AIM:To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery. METHODS:The medical records of patients who underwent endoscopic self-expanding metal stents (SEMS) insertion for colorectal obstructions between February 2004 and Janua...

journal_title：World journal of gastroenterology

authors： Kim JH,Lee JJ,Cho JH,Kim KO,Chung JW,Kim YJ,Kwon KA,Park DK,Kim JH

更新日期：2014-10-14 00:00:00

abstract：:Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been compli...

journal_title：World journal of gastroenterology

authors： Shen YZ,Wang ZY,Lu HZ

更新日期：2012-10-07 00:00:00