ADAM17 mRNA expression and pathological features of hepatocellular carcinoma.

abstract：AIM:To evaluate the clinical characteristics of nonvariceal upper gastrointestinal hemorrhage (NGIH) in patients with chronic kidney disease (CKD). METHODS:From 2003 to 2010, a total of 72 CKD patients (male n = 52, 72.2%; female n = 20, 27.8%) who had undergone endoscopic treatments for NGIH were retrospectively iden...

journal_title：World journal of gastroenterology

authors： Bang CS,Lee YS,Lee YH,Sung H,Park HJ,Kim HS,Kim JB,Baik GH,Kim YS,Yoon JH,Kim DJ,Suk KT

更新日期：2013-11-21 00:00:00

abstract：AIM:To investigate whether the apoptotic activities of 8-bromo-7-methoxychrysin (BrMC) involve reactive oxygen species (ROS) generation and c-Jun N-terminal kinase (JNK) activation in human hepatocellular carcinoma cells (HCC). METHODS:HepG2, Bel-7402 and L-02 cell lines were cultured in vitro and the apoptotic effect...

journal_title：World journal of gastroenterology

authors： Yang XH,Zheng X,Cao JG,Xiang HL,Liu F,Lv Y

更新日期：2010-07-21 00:00:00

abstract：AIM:To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS:Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growt...

journal_title：World journal of gastroenterology

authors： Luo J,Chen YJ,Wang WY,Zou SQ

更新日期：2008-09-14 00:00:00

abstract：:It has been reported that host defense responses, such as phagocytic function of neutrophils and natural killer (NK) cell activity of lymphocytes, are impaired in cirrhotic patients. This review will concentrate on the impairment of innate immune responses in decompensated cirrhotic patients and the effect of the trea...

journal_title：World journal of gastroenterology

authors： Nakamura I

更新日期：2014-06-21 00:00:00

abstract：AIM:To investigate the role of heme oxygenase-1 (HO-1) in pathogenesis of experimental hepatorenal syndrome (HRS). METHODS:Rats were divided into liver cirrhotic group, zinc protoporphyrin IX (ZnPP) treatment group, cobalt protoporphyrin (CoPP) treatment group and sham group. Biliary cirrhosis was established by bile ...

journal_title：World journal of gastroenterology

authors： Guo SB,Duan ZJ,Li Q,Sun XY

更新日期：2011-01-21 00:00:00

abstract：AIM:To explore the expression of macrophage inflammatory protein-1alpha (MIP-1alpha) in Kupffer cells (KCs) following liver ischemia/reperfusion injury IRI in rats. METHODS:Forty male SD rats were divided randomly into five groups. A model of partial warm ischemia/reperfusion injury in the rat liver was established. K...

journal_title：World journal of gastroenterology

authors： Ma W,Wang ZR,Shi L,Yuan Y

更新日期：2006-06-28 00:00:00

abstract：AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

journal_title：World journal of gastroenterology

authors： Shi D,Liao SH,Geng JP

更新日期：2010-09-07 00:00:00

abstract：:Mesenchymal stem cells (MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro. It has recently been observed that MSC may also exert a profound immunosuppressive and anti-inflammatory effect both in vitro and in vivo with consequent potential use in autoimmune disorde...

journal_title：World journal of gastroenterology

authors： Taddio A,Tommasini A,Valencic E,Biagi E,Decorti G,De Iudicibus S,Cuzzoni E,Gaipa G,Badolato R,Prandini A,Biondi A,Ventura A

更新日期：2015-04-14 00:00:00

abstract：:Colorectal anastomotic leakage (CAL) remains a major complication after colorectal surgery. Despite all efforts during the last decades, the incidence of CAL has not decreased. In this review, we summarize the available strategies regarding prevention, prediction and intervention of CAL and categorize them into three ...

journal_title：World journal of gastroenterology

authors： Sparreboom CL,Wu ZQ,Ji JF,Lange JF

更新日期：2016-08-28 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：AIM:To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia. METHODS:We genotyped 355 Estonians by polymerase chain reaction and direct sequencing. Milk consumption was analyzed by a que...

journal_title：World journal of gastroenterology

authors： Lember M,Torniainen S,Kull M,Kallikorm R,Saadla P,Rajasalu T,Komu H,Järvelä I

更新日期：2006-12-07 00:00:00

abstract：AIM:To report on our large German collective and updated data of 142 patients with autoimmune hepatitis (AIH) type 1. METHODS:Key investigations performed were liver biopsy, serum autoantibodies as well as serum markers such as IgG and elevated transaminases. Antinuclear antigen (ANA) and smooth muscle antigen (SMA) a...

journal_title：World journal of gastroenterology

authors： Teufel A,Wörns M,Weinmann A,Centner C,Piendl A,Lohse AW,Galle PR,Kanzler S

更新日期：2006-09-14 00:00:00

abstract：AIM:To demonstrate the possible associations between genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2) and esophageal squamous cell dysplasia (ESCD). METHODS:All participants came from an area of high incidence of esophageal cancer and underwent an endoscopic staining examination; biopsies were taken from a no...

journal_title：World journal of gastroenterology

authors： Zhou YZ,Diao YT,Li H,Li HQ,Ma Q,Cui J

更新日期：2010-07-21 00:00:00

abstract：:Alcoholism and cirrhosis, which are two of the most serious health problems worldwide, have a broad spectrum of clinical outcomes. Both diseases are influenced by genetic susceptibility and cultural traits that differ globally but are specific for each population. In contrast to other regions around the world, Mexican...

journal_title：World journal of gastroenterology

authors： Roman S,Zepeda-Carrillo EA,Moreno-Luna LE,Panduro A

更新日期：2013-11-28 00:00:00

abstract：:AIM:To investigate the characteristics of newly established four hepatocellular carcinoma cell lines (SNU-739, SNU-761, SNU-878 and SNU-886) from Korean hepatocellular cancer patients.METHODS:Morphologic and genetic studies were done.RESULTS:All four lines grew as a monolayer with an adherent pattern, and their doubli...

journal_title：World journal of gastroenterology

authors： Lee JH,Ku JL,Park YJ,Lee KU,Kim WH,Park JG

更新日期：1999-08-01 00:00:00

abstract：AIM:To investigate the effect of dermatan sulfate (DS) derivatives on platelet surface P-selectin expression and blood activated protein C (APC) activity in patients with inflammatory bowel disease (IBD), and to clarity the anti-inflammatory mechanism of DS derivatives. METHODS:Dermatan sulfate (DS) was sulfated with ...

journal_title：World journal of gastroenterology

authors： Ji SL,Du HY,Chi YQ,Cui HF,Cao JC,Geng MY,Guan HS

更新日期：2004-12-01 00:00:00

abstract：AIM:To explore the contribution of AXIN1, AXIN2 and beta-catenin, components of Wnt signaling pathway, to the carcinogenesis of gastric cancer (GC), we examined AXIN1, AXIN2 exon7 and CTNNB1 (encoding beta-catenin) exon3 mutations in 70 GCs. METHODS:The presence of mutations was identified by polymerase chain reaction...

journal_title：World journal of gastroenterology

authors： Pan KF,Liu WG,Zhang L,You WC,Lu YY

更新日期：2008-03-14 00:00:00

abstract：AIM:To investigate the effectiveness of 4 d' anti-Helicobacter pylori therapy on the H pylori-infected Mongolian gerbils based on physiological and pathological changes. METHODS:We used 6-wk-old male gerbils orally inoculated with H pylori (ATCC43504, 2X10(8) CFU/mL). Seven weeks after H pylori inoculation, the animal...

journal_title：World journal of gastroenterology

authors： Chang CC,Chen SH,Lien GS,Lee YJ,Lou HY,Hsieh CR,Fang CL,Pan S

更新日期：2005-02-21 00:00:00

abstract：AIM:To investigate the expression of p28/gankyrin gene and its role in the carcinogenetic process of human hepatocellular carcinoma (HCC). METHODS:64 specimens of HCC and para-carcinoma tissues, 22 specimens of non-tumor liver tissues (7 normal, 15 cirrhosis), 10 specimens of normal human tissues and 5 hepatoma cell l...

journal_title：World journal of gastroenterology

authors： Fu XY,Wang HY,Tan L,Liu SQ,Cao HF,Wu MC

更新日期：2002-08-01 00:00:00

abstract：:This paper pays a tribute to Dr. Frank I Tovey on his 90th birthday which happens on September 1, 2011, and briefly describes the major findings in his research career and contributions as follows. The geographical prevalence of duodenal ulceration is related to staple diets. Unrefined wheat and maize, soya, certain p...

journal_title：World journal of gastroenterology

authors： Ma LS

更新日期：2011-08-21 00:00:00

abstract：:Solid-pseudopapillary tumor (SPT) is a rare neoplasm of the pancreas that usually occurs in young females. It is generally considered a low-grade malignant tumor that can remain asymptomatic for several years. The occurrence of infiltrating varieties of SPT is around 10%-15%. Between 1986 and 2006, 282 cystic tumors o...

journal_title：World journal of gastroenterology

authors： Sperti C,Berselli M,Pasquali C,Pastorelli D,Pedrazzoli S

更新日期：2008-02-14 00:00:00

abstract：AIM:To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation-ship between their expression and clinico-pathological features. METHODS:The expression levels of Eag1 protein were determined in 76 cancer tissues with paired non-cancerous matched tissues as well as 9 colorect...

journal_title：World journal of gastroenterology

authors： Ding XW,Yan JJ,An P,Lü P,Luo HS

更新日期：2007-02-28 00:00:00

abstract：:Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity i...

journal_title：World journal of gastroenterology

authors： Mori H,Rafiq K,Kobara H,Nishiyama N,Fujihara S,Yachida T,Ayagi M,Tani J,Miyoshi H,Masaki T

更新日期：2014-02-14 00:00:00

abstract：AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

journal_title：World journal of gastroenterology

authors： Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

更新日期：2002-02-01 00:00:00

abstract：AIM:To summarize progress in the study of K-ras gene studies in pancreatic cancer and its potential clinical significance in screening test for early detection of pancreatic cancer, and to differentiate pancreatic cancer from chronic pancreatitis in recent decade. METHODS:Literature search (MEDLINE 1986-2003) was perf...

journal_title：World journal of gastroenterology

authors： Mu DQ,Peng YS,Xu QJ

更新日期：2004-02-15 00:00:00

abstract：AIM:To investigate the prevalence of gastroesophageal reflux disease (GERD) in patients with a laryngoscopic diagnosis of laryngopharyngeal reflux (LPR). METHODS:Between May 2011 and October 2011, 41 consecutive patients with laryngopharyngeal symptoms (LPS) and laryngoscopic diagnosis of LPR were empirically treated ...

journal_title：World journal of gastroenterology

authors： de Bortoli N,Nacci A,Savarino E,Martinucci I,Bellini M,Fattori B,Ceccarelli L,Costa F,Mumolo MG,Ricchiuti A,Savarino V,Berrettini S,Marchi S

更新日期：2012-08-28 00:00:00

abstract：:We report a case of cerebral lipiodol embolism (CLE) after transarterial chemoembolization (TACE) for unresectable hepatic carcinoma (HCC). A 54-year-old man with unresectable HCC underwent TACE via the right hepatic artery and right inferior phrenic artery using a mixture of 40 mg pirarubicin and 30 mL lipiodol. His ...

journal_title：World journal of gastroenterology

authors： Jia ZZ,Tian F,Jiang GM

更新日期：2012-08-14 00:00:00

abstract：:The severity of fecal incontinence widely varies and can have dramatic devastating impacts on a person's life. Fecal incontinence is common, though it is often under-reported by patients. In addition to standard treatment options, new treatments have been developed during the past decade to attempt to effectively trea...

journal_title：World journal of gastroenterology

authors： Van Koughnett JA,Wexner SD

更新日期：2013-12-28 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), leading to fibrosis and potentially cirrhosis, and it is one of the most common causes of liver disease worldwide. NAFLD is associated with other medical conditions such as metabolic syndrome, obesity, cardio...

journal_title：World journal of gastroenterology

authors： Schwenger KJ,Allard JP

更新日期：2014-02-21 00:00:00