Abstract:
:Solid-pseudopapillary tumor (SPT) is a rare neoplasm of the pancreas that usually occurs in young females. It is generally considered a low-grade malignant tumor that can remain asymptomatic for several years. The occurrence of infiltrating varieties of SPT is around 10%-15%. Between 1986 and 2006, 282 cystic tumors of the pancreas were observed. Among them a SPT was diagnosed in 8 patients (2.8%) with only one infiltrating variety. This was diagnosed in a 49-year-old female 13 years after the sonographic evidence of a small pancreatic cystic lesion interpreted as a pseudocyst. The tumor invaded a long segment of the portal-mesenteric vein confluence, and was removed with a total pancreatectomy, resection of the portal vein and reconstruction with the internal jugular vein. Histological examination confirmed the R-0 resection of the primary SPT, although a vascular invasion was demonstrated. The postoperative course was uneventful, but 32 mo after surgery the patient experienced diffuse liver metastases. Chemotherapy with different drugs was started. The patient is alive and symptom-free, with stable disease, 75 mo after surgery. Twenty-five patients with invasion of the portal vein and/or of mesenteric vessels were retrieved from the literature, 16 recent patients with tumor relapse after potentially curative resection were also retrieved. The best treatment remains a radical resection whenever possible, even in locally advanced or metastatic disease. The role of chemotherapy, and/or radiotherapy, is still to be defined.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Sperti C,Berselli M,Pasquali C,Pastorelli D,Pedrazzoli Sdoi
10.3748/wjg.14.960subject
Has Abstractpub_date
2008-02-14 00:00:00pages
960-5issue
6eissn
1007-9327issn
2219-2840journal_volume
14pub_type
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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pub_type: 社论,评审
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pub_type: 临床试验,杂志文章
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pub_type: 社论,评审
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2010-02-21 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-11-28 00:00:00
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pub_type: 杂志文章
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更新日期:2009-07-14 00:00:00