Effect of p27(KIP1) on cell cycle and apoptosis in gastric cancer cells.

abstract：AIM:To investigate the prevalence of celiac disease (CD) in adult patients referred to an open access gastroenterology clinic in the south of Italy and submitted to esophago-gastro-duodenoscopy (EGD) for evaluation of refractory functional dyspepsia. METHODS:Seven hundred and twenty six consecutive dyspeptic patients ...

journal_title：World journal of gastroenterology

authors： Giangreco E,D'agate C,Barbera C,Puzzo L,Aprile G,Naso P,Bonanno G,Russo FP,Nicoletti A,Incarbone S,Trama G,Russo A

更新日期：2008-12-07 00:00:00

abstract：:In colon cancer, classic disease staging remains the key prognosis and treatment determinant. Although adjuvant chemotherapy has an established role in stage III colon cancer patients, in stage II it is still a subject of controversy due to its restriction to a small subgroup of patients with high-risk histopathologic...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Souglakos J,Georgoulias V

更新日期：2014-06-14 00:00:00

abstract：AIM:To explore the genetic diversities of UL144 open reading frame (ORF) of cytomegalovirus DNA detected in colon tissue from infants with Hirschsprung's disease (HD) by sequencing UL144 DNA in 23 aganglionic colon tissue and 4 urine samples from 25 HD infants. METHODS:Nest PCR was performed for amplification of the U...

journal_title：World journal of gastroenterology

authors： Mao ZQ,Huang Y,Sun M,Ruan Q,Qi Y,He R,Huang YJ,Ma YP,Ji YH,Sun ZR,Gao H

更新日期：2007-08-28 00:00:00

abstract：:A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He...

journal_title：World journal of gastroenterology

authors： Sayana H,Yousef O,Clarkston WK

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:Public awareness of colorectal cancer (CRC) and uptake of CRC screening remain challenges. The viewpoints of the target population (asymptomatic individuals older than 50) regarding CRC screening information sources and the reasons for and against participation in CRC screening are not well known in the Czec...

journal_title：World journal of gastroenterology

authors： Kroupa R,Ondrackova M,Kovalcikova P,Dastych M,Pavlik T,Kunovsky L,Dolina J

更新日期：2019-03-07 00:00:00

abstract：AIM:To analyse the role of genetic susceptibility and environmental factors in the process of esophageal cancer (EC) formation in Xi'an, China. METHODS:A hospital based case-control study, combined with molecular epidemiological method, was carried out. A total of 127 EC cases and 101 controls were interviewed with qu...

journal_title：World journal of gastroenterology

authors： Wang AH,Sun CS,Li LS,Huang JY,Chen QS,Xu DZ

更新日期：2004-04-01 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic inflammatory bowel condition characterised by a relapsing and remitting course. Symptom control has been the traditional mainstay of medical treatment. It is well known that histological inflammatory activity persists despite adequate symptom control and absence of endoscopic infla...

journal_title：World journal of gastroenterology

authors： Mohammed N,Subramanian V

更新日期：2016-11-14 00:00:00

abstract：AIM:To elucidate cell proliferation in erosive reflux disease (ERD) and non-erosive reflux disease (NERD), we evaluated markers in squamous epithelial cells. METHODS:Thirty-four consecutive patients with gastroesophageal-reflux-disease-related symptoms (21 NERD and 13 ERD) were evaluated for the enrolment into the stu...

journal_title：World journal of gastroenterology

authors： Calabrese C,Montanaro L,Liguori G,Brighenti E,Vici M,Gionchetti P,Rizzello F,Campieri M,Derenzini M,Trerè D

更新日期：2011-10-28 00:00:00

abstract：:AIM:To study the peripheral mechanism of the inhibitory effect of intra-third ventricular administration (icv) of histamine (HA) on gastric acid secretion in rats.METHODS:Gastric acid was continuously washed with 37&mgr; saline by a perfusion pump in male adrenalectomized SD rats. Drugs were injected intravenously (iv...

journal_title：World journal of gastroenterology

authors： Zhang ZF,Wang ZL,Lu GQ

更新日期：1998-06-01 00:00:00

abstract：AIM:To study the induction of T cellular immune responses in BALB/c mice immunized with uric acid and dendritic cells (DCs) pulsed with hepatitis B virus surface antigen (HBsAg). METHODS:DCs were generated from bone-marrow cells of BABL/c mice, and then pulsed or unpulsed with HBsAg protein (HBsAg-pulsed-DCs or unpuls...

journal_title：World journal of gastroenterology

authors： Ma XJ,Tian DY,Xu D,Yang DF,Zhu HF,Liang ZH,Zhang ZG

更新日期：2007-02-21 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：:Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with...

journal_title：World journal of gastroenterology

authors： Inchingolo R,Posa A,Mariappan M,Spiliopoulos S

更新日期：2019-08-28 00:00:00

abstract：AIM:To elucidate the effect of angiogenesis inhibitor, Linomide, on tumor growth and metastasis in nude mice implanted with human gastric cancer. METHODS:A metastatic model of gastric cancer was established using orthotopic implantation of histologically intact tumor tissues into the gastric wall of nude mice. Linomid...

journal_title：World journal of gastroenterology

authors： Tao HQ,Lin YZ,Yin HR,Gu QL,Zhu ZG,Yao M

更新日期：1997-09-15 00:00:00

abstract：AIM:To study the effect of rosiglitazone, which is a ligand of peroxisome proliferator-activated receptor gamma (PPARgamma), on the expression of PPARgamma in hepatic stellate cells (HSCs) and on the biological characteristics of HSCs. METHODS:The activated HSCs were divided into three groups: control group, 3 micromo...

journal_title：World journal of gastroenterology

authors： Guo YT,Leng XS,Li T,Peng JR,Song SH,Xiong LF,Qin ZZ

更新日期：2005-08-14 00:00:00

abstract：AIM:To explore the effects of the nucleoside analogues beta-L-D4A and beta-LPA on hepatitis B virus (HBV) promoters. METHODS:Four HBV promoters were amplified by polymerase chain reaction (PCR) and subcloned into the expression vector pEGFP-1. The four recombinants controlled by HBV promoters were confirmed by restric...

journal_title：World journal of gastroenterology

authors： He XX,Lin JS,Chang Y,Zhang YH,Li Y,Wang XY,Xu D,Cheng XM

更新日期：2008-03-28 00:00:00

abstract：AIM:To investigate the feasibility of a single-use endoscopy as an alternative procedure to nasogastric lavage in patients with acute gastrointestinal (GI) bleeding. METHODS:Patients who presented with hematemesis, melena or hematochezia were enrolled in this study. EG scan™ and conventional esophagogastroduodenoscopy...

journal_title：World journal of gastroenterology

authors： Cho JH,Kim HM,Lee S,Kim YJ,Han KJ,Cho HG,Song SY

更新日期：2013-01-07 00:00:00

abstract：BACKGROUND:Conventionally, the low luminous intensity, low image resolution, and difficulty in operation have been reported with the ultrathin endoscope. However, it has markedly advanced recently. The improvement of the diagnostic ability is expected. AIM:To compare the early gastric cancer diagnostic ability of an u...

journal_title：World journal of gastroenterology

authors： Suzuki T,Kitagawa Y,Nankinzan R,Yamaguchi T

更新日期：2019-03-21 00:00:00

abstract：AIM:To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis. METHODS:The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM). Eight databases including M...

journal_title：World journal of gastroenterology

authors： Dong ZY,Wang GL,Liu X,Liu J,Zhu DZ,Ling CQ

更新日期：2012-04-14 00:00:00

abstract：AIM:To evaluate the diagnostic value of gadobenate dimeglumine (Gd-BOPTA)-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in evaluating hepatic fibrosis and hepatitis. METHODS:Hepatocyte-phase images of Gd-BOPTA-enhanced MRI were retrospectively evaluated in 76 patients with chronic liver disease. These pat...

journal_title：World journal of gastroenterology

authors： Li XM,Chen Z,Xiao EH,Shang QL,Ma C

更新日期：2017-05-07 00:00:00

abstract：:Corticosteroids and immunomodulators have been the mainstay therapies for Crohn's disease. Corticosteroids are highly effective to control symptoms in the short-term, but they are not effective in maintaining remission, they heal the mucosa in a reduced proportion of cases, and long-time exposure is associated with an...

journal_title：World journal of gastroenterology

authors： Ricart E,García-Bosch O,Ordás I,Panés J

更新日期：2008-09-28 00:00:00

abstract：AIM:To examined the bile acid receptor TGR5 expression in squamous mucosa, Barrett's mucosa, dysplasia and esophageal adenocarcinoma (EA). METHODS:Slides were stained with TGR5 antibody. The staining intensity was scored as 1+, 2+ and 3+. The extent of staining (percentage of cells staining) was scored as follows: 1+,...

journal_title：World journal of gastroenterology

authors： Marketkar S,Li D,Yang D,Cao W

更新日期：2017-02-28 00:00:00

abstract：AIM:To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this process. METHODS:Using migration assay, MTT assay and Matrigel assay, the effect of alphastatin on vascular endothelial cells (ECs) was evaluated in vitro. SPK ...

journal_title：World journal of gastroenterology

authors： Chen L,Li T,Li R,Wei B,Peng Z

更新日期：2006-07-14 00:00:00

abstract：AIM:To confirm if p53 mutation could be a routine predictive marker for the prognosis of hepatocellular carcinoma (HCC) patients. METHODS:Two hundreds and forty-four formalin-fixed paraffin-embedded tumor samples of the patients with HCC receiving liver resection were detected for nuclear accumulation of p53. The perc...

journal_title：World journal of gastroenterology

authors： Qin LX,Tang ZY,Ma ZC,Wu ZQ,Zhou XD,Ye QH,Ji Y,Huang LW,Jia HL,Sun HC,Wang L

更新日期：2002-06-01 00:00:00

abstract：AIM:To immunohistochemically examine micrometastasis and VEGF-C expression in hilar bile duct carcinoma (HBDC) and to evaluate the clinical significance of the results. METHODS:A total of 361 regional lymph nodes from 25 patients with node-negative HBDC were immunostained with an antibody against cytokeratins 8 and 18...

journal_title：World journal of gastroenterology

authors： Taniguchi K,Iida T,Hori T,Yagi S,Imai H,Shiraishi T,Uemoto S

更新日期：2006-04-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) is a prevalent, worldwide, chronic infection. Choice of treatment can be modified according to antibiotic-resistance rates of H. pylori. The ideal therapeutic regimen for H. pylori infection should achieve an eradication rate of ≥ 80%. In some countries, triple therapy with a proton-pum...

journal_title：World journal of gastroenterology

authors： Alahdab YO,Kalayci C

更新日期：2014-05-14 00:00:00

abstract：:The fact that the acid-secreting parietal cells undergo continuous renewal has been ignored by many gastroenterologists and cell biologists. In the past, it was thought that these cells were static. However, by using (3)H-thymidine radioautography in combination with electron microscopy, it was possible to demonstrate...

journal_title：World journal of gastroenterology

authors： Karam SM

更新日期：2010-02-07 00:00:00

abstract：AIM:To evaluate the association between X-ray cross-complementing gene 1 (XRCC1) genetic polymorphism Arg399Gln and gastric cancer risk by means of meta-analysis. METHODS:We searched PubMed and NCBI up to June 1, 2008. A total of 16 clinical trials and reports were identified, but only 8 trials qualified under our sel...

journal_title：World journal of gastroenterology

authors： Geng J,Zhang YW,Huang GC,Chen LB

更新日期：2008-11-21 00:00:00

abstract：AIM:To investigate the association between babA2 gene and peptic ulcer disease (PUD) and gastric cancer (GC) in Helicobacter pylori-infected populations. METHODS:We evaluated the relationship between babA2 and clinical outcomes (PUD and GC) using a meta-analysis. A literature search was performed using the PubMed and ...

journal_title：World journal of gastroenterology

authors： Chen MY,He CY,Meng X,Yuan Y

更新日期：2013-07-14 00:00:00

abstract：:We report an extremely rare case where a mesenchymal differentiation, especially embryonal sarcoma, was demonstrated in cholangiocarcinoma. At autopsy, a yellowish-white tumor (15 cm x 12 cm) was found in the right hepatic lobe, and there were several daughter nodules in both hepatic lobes. Histologically, most of the...

journal_title：World journal of gastroenterology

authors： Sumiyoshi S,Kikuyama M,Matsubayashi Y,Kageyama F,Ide Y,Kobayashi Y,Nakamura H

更新日期：2007-02-07 00:00:00

abstract：:To our knowledge, stercoral perforation of the colon is rarely seen with fewer than 90 cases reported in the literature till date. We explored the principles of management to prevent impending mortality in five patients with this condition. Five patients, two males and three females, whose median age was 64 years, had...

journal_title：World journal of gastroenterology

authors： Huang WS,Wang CS,Hsieh CC,Lin PY,Chin CC,Wang JY

更新日期：2006-01-21 00:00:00