Genetic polymorphism of UL144 open reading frame of human cytomegalovirus DNA detected in colon samples from infants with Hirschsprung's disease.

Abstract:

AIM:To explore the genetic diversities of UL144 open reading frame (ORF) of cytomegalovirus DNA detected in colon tissue from infants with Hirschsprung's disease (HD) by sequencing UL144 DNA in 23 aganglionic colon tissue and 4 urine samples from 25 HD infants. METHODS:Nest PCR was performed for amplification of the UL144 gene. The UL144 gene was analyzed with softwares, such as DNAclub, BioEdit, PROSITE database, and DNAstar. RESULTS:The strains from HD patients were distributed among three genotypes of UL144: group 1A (64%), group 2 (24%), and group 3 (12%). The UL144 genotypes between strains from HD and control group were compared by chi square test (c2 = 1.870, P = 0.393). Strains from the colon were sporadically distributed in UL144 genotypes. CONCLUSION:There are genetic diversities of UL144 ORF in colon tissue of infants with HD. However, cytomegalovirus UL144 genotypes are not associated with clinical manifestations of HD.

journal_name

World J Gastroenterol

authors

Mao ZQ,Huang Y,Sun M,Ruan Q,Qi Y,He R,Huang YJ,Ma YP,Ji YH,Sun ZR,Gao H

doi

10.3748/wjg.v13.i32.4350

subject

Has Abstract

pub_date

2007-08-28 00:00:00

pages

4350-4

issue

32

eissn

1007-9327

issn

2219-2840

journal_volume

13

pub_type

杂志文章
  • Enhanced expression of epidermal growth factor receptor gene in gastric mucosal cells by the serum derived from rats treated with electroacupuncture at stomach meridian acupoints.

    abstract:AIM:To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS:The stress-induced gastric mucosal injury in rat model was established by water-immersion and restra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i34.5557

    authors: Yang ZB,Yan J,Zou XP,Yi SX,Chang XR,Lin YP,Li XP

    更新日期:2006-09-14 00:00:00

  • Risk factors and therapeutic response in Chinese patients with peptic ulcer disease.

    abstract:AIM:To assess the risk factors and the efficacy of medications of patients with gastric and duodenal ulcers among Chinese patients in Taiwan. METHODS:Patients with peptic ulcers, diagnosed by upper endoscopy, were retrospectively collected between January 2008 and December 2008. The differences were compared. RESULTS...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i16.2017

    authors: Lee SW,Chang CS,Lee TY,Yeh HZ,Tung CF,Peng YC

    更新日期:2010-04-28 00:00:00

  • Contrast-enhanced harmonic endoscopic ultrasonography for assessment of lymph node metastases in pancreatobiliary carcinoma.

    abstract:AIM:To assess the usefulness of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) for lymph node metastasis in pancreatobiliary carcinoma. METHODS:All patients suspected of pancreatobiliary carcinoma with visible lymph nodes after standard EUS between June, 2009 and January, 2012 were enrolled. In the pri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i12.3381

    authors: Miyata T,Kitano M,Omoto S,Kadosaka K,Kamata K,Imai H,Sakamoto H,Nisida N,Harwani Y,Murakami T,Takeyama Y,Chiba Y,Kudo M

    更新日期:2016-03-28 00:00:00

  • Mitochondrial microsatellite instability in gastric cancer and its precancerous lesions.

    abstract:AIM:To evaluate the role of mitochondrial microsatellite instability (mtMSI) in gastric carcinogenesis. METHODS:MtMSI was measured with PCR-single strand conformation polymorphism (PCR-SSCP) in 68 cases of advanced gastric cancer, 40 cases of chronic gastritis, 30 cases of intestinal metaplasia and 20 cases of dysplas...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i6.800

    authors: Ling XL,Fang DC,Wang RQ,Yang SM,Fang L

    更新日期:2004-03-15 00:00:00

  • Indications and surgical options for small bowel, large bowel and perianal Crohn's disease.

    abstract::Despite advancements in medical therapy of Crohn's disease (CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for sur...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i40.8892

    authors: Toh JW,Stewart P,Rickard MJ,Leong R,Wang N,Young CJ

    更新日期:2016-10-28 00:00:00

  • Incidents and adverse events of endoscopic ultrasound-guided fine-needle aspiration for pancreatic cystic lesions.

    abstract:AIM:To evaluate the diagnostic value and safety mainly regarding incidents of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for pancreatic cystic lesions (PCLs). METHODS:A total of 150 consecutive patients with suspected PCLs were prospectively enrolled from April 2015 to November 2016. We finally enro...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i30.5610

    authors: Du C,Chai NL,Linghu EQ,Li HK,Sun YF,Xu W,Wang XD,Tang P,Yang J

    更新日期:2017-08-14 00:00:00

  • Endoscopic treatment of Barrett's esophagus: From metaplasia to intramucosal carcinoma.

    abstract::The annual incidence of adenocarcinoma arising from Barrett's esophagus (BE) is approximately 0.5%. Through a process of gradual transformation from low-grade dysplasia to high-grade dysplasia (HGD), adenocarcinoma can develop in the setting of BE. The clinical importance of appropriate identification and treatment of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i30.3780

    authors: Chennat J,Waxman I

    更新日期:2010-08-14 00:00:00

  • Protective effects of oral glutathione on fasting-induced intestinal atrophy through oxidative stress.

    abstract:AIM:To determine whether oral glutathione (GSH) administration can alleviate the effects of fasting-induced intestinal atrophy in the small intestinal mucosa. METHODS:Rats were divided into eight groups. One group was fed ad libitum, another was fed ad libitum and received oral GSH, and six groups were administrated s...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i36.6650

    authors: Uchida H,Nakajima Y,Ohtake K,Ito J,Morita M,Kamimura A,Kobayashi J

    更新日期:2017-09-28 00:00:00

  • Prospective observational multicenter study to define a diagnostic algorithm for biliary candidiasis.

    abstract:AIM:To develop an algorithm to improve the diagnosis and treatment of patients with biliary candidiasis. METHODS:We performed a prospective study of 127 patients who underwent endoscopic retrograde cholangiopancreatography, for various biliary disorders, at 3 tertiary referral centers in Germany from July 2011 through...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v20.i34.12260

    authors: Lenz P,Eckelskemper F,Erichsen T,Lankisch T,Dechêne A,Lubritz G,Lenze F,Beyna T,Ullerich H,Schmedt A,Domagk D

    更新日期:2014-09-14 00:00:00

  • Necrosis of a large hepatic tumor after hemorrhage and subsequent selective arterial embolization.

    abstract::This case report describes a young female patient presenting with acute intra-abdominal hemorrhage originating from a large tumor in the liver, most likely a hepatocellular adenoma. The bleeding was stopped by selective embolization of right hepatic artery branches. Subsequently, partial hepatectomy was performed afte...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i37.6059

    authors: Huurman VA,Stoot JH,van der Linden E,Terpstra OT,Schaapherder AF

    更新日期:2006-10-07 00:00:00

  • Prevalence and outcomes of pancreatic cystic neoplasms in liver transplant recipients.

    abstract:AIM:To determine the prevalence, characteristics and clinical course of pancreatic cystic neoplasms (PCNs) in liver transplantation (LT) recipients. METHODS:We retrospectively studied consecutive patients who underwent LT between January 1998 to April 2016. Clinical and laboratory data were obtained from patient medic...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i48.8526

    authors: Liu K,Joshi V,van Camp L,Yang QW,Baars JE,Strasser SI,McCaughan GW,Majumdar A,Saxena P,Kaffes AJ

    更新日期:2017-12-28 00:00:00

  • Prospects for nucleic acid-based therapeutics against hepatitis C virus.

    abstract::In this review, we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus (HCV) infection. Because the HCV genome is present exclusively in RNA form during replication, various nucleic acid-based therapeutic approaches targeting the HCV genome, such as ribozymes, aptamers,...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i47.8949

    authors: Lee CH,Kim JH,Lee SW

    更新日期:2013-12-21 00:00:00

  • Small bowel capsule endoscopy and treat-to-target in Crohn's disease: A systematic review.

    abstract:BACKGROUND:Crohn's disease (CD) can affect the entire gastrointestinal tract. Proximal small bowel (SB) lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries. The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prog...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i31.4534

    authors: Le Berre C,Trang-Poisson C,Bourreille A

    更新日期:2019-08-21 00:00:00

  • Incidence of hepatocellular carcinoma in outpatients with cirrhosis in Brazil: A 10-year retrospective cohort study.

    abstract:AIM:To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients. METHODS:In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i46.10219

    authors: Appel-da-Silva MC,Miozzo SA,Dossin IA,Tovo CV,Branco F,de Mattos AA

    更新日期:2016-12-14 00:00:00

  • Generation of human/rat xenograft animal model for the study of human donor stem cell behaviors in vivo.

    abstract:AIM:To accurately and realistically elucidate human stem cell behaviors in vivo and the fundamental mechanisms controlling human stem cell fates in vivo, which is urgently required in regenerative medicine and treatments for some human diseases, a surrogate human-rat chimera model was developed. METHODS:Human-rat chim...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i19.2707

    authors: Sun Y,Xiao D,Pan XH,Zhang RS,Cui GH,Chen XG

    更新日期:2007-05-21 00:00:00

  • Detection of carcinoembryonic antigen mRNA in peritoneal washes from gastric cancer patients and its clinical significance.

    abstract:AIM:To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS:The carcinoembryonic antigen (CEA) mRNA levels in peritoneal washes from 65 cases of gastric cancer were detected by real-time ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i9.1408

    authors: Zhang YS,Xu J,Luo GH,Wang RC,Zhu J,Zhang XY,Nilsson-Ehle P,Xu N

    更新日期:2006-03-07 00:00:00

  • Mucosal blood flow measurements using laser Doppler perfusion monitoring.

    abstract::Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insufficiency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signallin...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.198

    authors: Hoff DA,Gregersen H,Hatlebakk JG

    更新日期:2009-01-14 00:00:00

  • Comparative quantification of human intestinal bacteria based on cPCR and LDR/LCR.

    abstract:AIM:To establish a multiple detection method based on comparative polymerase chain reaction (cPCR) and ligase detection reaction (LDR)/ligase chain reaction (LCR) to quantify the intestinal bacterial components. METHODS:Comparative quantification of 16S rDNAs from different intestinal bacterial components was used to ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i3.268

    authors: Tang ZR,Li K,Zhou YX,Xiao ZX,Xiao JH,Huang R,Gu GH

    更新日期:2012-01-21 00:00:00

  • Combined therapy of allantoin, metronidazole, dexamethasone on the prevention of intra-abdominal adhesion in dogs and its quantitative analysis.

    abstract:AIM:To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS:20 dogs of both sexes were used in this study. After laparotomy under anesthesia, 2 cm section of cecal end was clamped and ligated, then 1 cm cecum...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i3.568

    authors: Wang XC,Gui CQ,Zheng QS

    更新日期:2003-03-01 00:00:00

  • Imaging features of intraductal papillary mucinous neoplasms of the pancreas in multi-detector row computed tomography.

    abstract:AIM:To retrospectively evaluate the imaging features of pancreatic intraductal papillary mucinous neoplasms (IPMNs) in multi-detector row computed tomography (MDCT). METHODS:A total of 20 patients with pathologically-confirmed intraductal papillary mucinous neoplasms (IPMNs) were included in this study. Axial MDCT ima...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.4037

    authors: Tan L,Zhao YE,Wang DB,Wang QB,Hu J,Chen KM,Deng XX

    更新日期:2009-08-28 00:00:00

  • Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.

    abstract:AIM:To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats. METHODS:Gastric injury was assessed by measuring ulcerated legions 4 h after indomethacin (25 mg/kg) administration. Small intestinal injury was assessed by measuring ulcerated legions 24 h after indomet...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i10.2641

    authors: Yamamoto A,Itoh T,Nasu R,Nishida R

    更新日期:2014-03-14 00:00:00

  • Calcium-sensing receptor: A new target for therapy of diarrhea.

    abstract::Management of acute diarrhea remains a global challenge, particularly in resource-limiting countries. Oral rehydration solution (ORS), a passive rehydrating therapy developed approximately 40 years ago, remains the mainstay treatment. Although ORS is effective for hydration, since it does not inhibit enterotoxin-media...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i9.2711

    authors: Cheng SX

    更新日期:2016-03-07 00:00:00

  • Endoscopic sphincterotomy in patients with stenosis of ampulla of Vater: three-year follow-up of exocrine pancreatic function and clinical symptoms.

    abstract:AIM:To investigate retrospectively the long-term effect of endoscopic sphincterotomy (ES) including exocrine pancreatic function in patients with stenosis of ampulla of Vater. METHODS:After diagnostic endoscopic retrograde cholangiopancreatography (ERCP) and ES because of stenosis of the ampulla of Vater (SOD Type I),...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i6.901

    authors: Ewald N,Marzeion AM,Bretzel RG,Kloer HU,Hardt PD

    更新日期:2007-02-14 00:00:00

  • Effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing gastrectomy.

    abstract:AIM:To investigate the effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing radical distal gastrectomy. METHODS:Within 24 h of intensive care unit management, patients with gastric cancer were enrolled after written informed consent and randomize...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v18.i21.2695

    authors: Liu HC,Zhou YB,Chen D,Niu ZJ,Yu Y

    更新日期:2012-06-07 00:00:00

  • Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives.

    abstract::The biosynthesis of prostaglandins and thromboxanes has been a focus of interest in the management of many liver diseases. Cyclooxygenases are the enzymes involved in the first step of the biosynthesis of these lipid mediators and selective inhibitors for these isoenzymes as well as pharmacological analogues of prosta...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v23.i20.3572

    authors: Martín-Sanz P,Casado M,Boscá L

    更新日期:2017-05-28 00:00:00

  • Drug therapy for ulcerative colitis.

    abstract::Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v10.i16.2311

    authors: Xu CT,Meng SY,Pan BR

    更新日期:2004-08-15 00:00:00

  • Meta-analysis of stapled hemorrhoidopexy vs LigaSure hemorrhoidectomy.

    abstract:AIM:To compare outcome of stapled hemorrhoidopexy (SH) vs LigaSure hemorrhoidectomy (LH) by a meta-analysis of available randomized controlled trials (RCTs). METHODS:Databases, including PubMed, EMBASE, the Cochrane Library, and the Science Citation Index updated to December 2012, were searched. The main outcomes meas...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v19.i29.4799

    authors: Yang J,Cui PJ,Han HZ,Tong DN

    更新日期:2013-08-07 00:00:00

  • Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas.

    abstract:AIM:To determine the incidence of Epstein Barr virus associated gastric carcinoma (GC) in Brazil and compare the expressions of apoptosis related proteins and nitric oxide synthases between EBV positive and negative gastric carcinoma. METHODS:In situ hybridization of EBV-encoded small RNA-1 (EBER-1) and PCR was perfor...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i31.4959

    authors: Begnami MD,Montagnini AL,Vettore AL,Nonogaki S,Brait M,Simoes-Sato AY,Seixas AQ,Soares FA

    更新日期:2006-08-21 00:00:00

  • Systematic review of modulators of benzodiazepine receptors in irritable bowel syndrome: is there hope?

    abstract::Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present sys...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v17.i38.4251

    authors: Salari P,Abdollahi M

    更新日期:2011-10-14 00:00:00

  • Therapeutic effect of Streptococcus thermophilus CRL 1190-fermented milk on chronic gastritis.

    abstract:AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i13.1622

    authors: Rodríguez C,Medici M,Mozzi F,Font de Valdez G

    更新日期:2010-04-07 00:00:00