Giant duodenal ulcers.

Abstract:

:Giant duodenal ulcers (GDUs) are a subset of duodenal ulcers that have historically resulted in greater morbidity than usual duodenal ulcers. Until recently, few cases had been successfully treated with medical therapy. However, the widespread use of endoscopy, the introduction of H-2 receptor blockers and proton pump inhibitors, and the improvement in surgical techniques all have revolutionized the diagnosis, treatment and outcome of this condition. Nevertheless, GDUs are still associated with high rates of morbidity, mortality and complications. Thus, surgical evaluation of a patient with a GDU should remain an integral part of patient care. These giant variants, while usually benign, can frequently harbor malignancy. A careful review of the literature highlights the important differences when comparing GDUs to classical peptic ulcers and why they must be thought of differently than their more common counterpart.

journal_name

World J Gastroenterol

authors

Newton EB,Versland MR,Sepe TE

doi

10.3748/wjg.14.4995

subject

Has Abstract

pub_date

2008-08-28 00:00:00

pages

4995-9

issue

32

eissn

1007-9327

issn

2219-2840

journal_volume

14

pub_type

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