Interferon-alpha induced severe thrombocytopenia: a case report and review of the literature.

Abstract:

:We report a case of severe thrombocytopenia following pegylated interferon-alpha 2a (Peg-IFN-alpha 2a) treatment of hepatitis C virus infection and summarize the clinical characteristics of 16 cases of IFN-alpha induced severe thrombocytopenia and its immune-mediated mechanism. Discontinuation of IFN-alpha and early administration of immunosuppressants are the effective therapy for IFN-alpha induced severe thrombocytopenia.

journal_name

World J Gastroenterol

authors

Li L,Han DK,Lu J

doi

10.3748/wjg.v16.i11.1414

subject

Has Abstract

pub_date

2010-03-21 00:00:00

pages

1414-7

issue

11

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

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