Combined glucocorticoid and antiviral therapy of hepatitis B virus-related liver failure.

abstract：AIM:To examine the expressions of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in rat fibrotic liver and in normal rat hepatic stellate cells, and to investigate the changes in their expressions in response to treatment with interleukin-10 (IL-10) and platelet-derived growth...

journal_title：World journal of gastroenterology

authors： Zhang LJ,Chen YX,Chen ZX,Huang YH,Yu JP,Wang XZ

更新日期：2004-09-01 00:00:00

abstract：AIM:To prospectively investigate the effectiveness and patient's tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS:A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with...

journal_title：World journal of gastroenterology

authors： Vradelis S,Kalaitzakis E,Sharifi Y,Buchel O,Keshav S,Chapman RW,Braden B

更新日期：2009-04-14 00:00:00

abstract：AIM:To analyze the clinical characteristics of small bowel tumors detected by double-balloon enteroscopy (DBE) and to evaluate the diagnostic value of DBE in tumors. METHODS:Four hundred and forty consecutive DBE examinations were performed in 400 patients (250 males and 150 females, mean age 46.9 ± 16.3 years, range ...

journal_title：World journal of gastroenterology

authors： Chen WG,Shan GD,Zhang H,Li L,Yue M,Xiang Z,Cheng Y,Wu CJ,Fang Y,Chen LH

更新日期：2013-06-21 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00

abstract：:A 46-year-old female patient with terminal ileum Crohn's disease and ankylosing spondylitis presented with recurrent angioedema and urticaria. Investigations ruled out hereditary angioedema, and environmental or food allergen triggers. She was diagnosed with chronic idiopathic urticaria with angioedema, and was treate...

journal_title：World journal of gastroenterology

authors： Habal F,Huang V

更新日期：2012-09-14 00:00:00

abstract：:Crohn's disease (CD) is a multifactorial disorder of unknown cause. Outstanding progress regarding the pathophysiology of CD has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD over the last years. However, many drugs have not been approved by regulatory ...

journal_title：World journal of gastroenterology

authors： Büning C,Lochs H

更新日期：2006-08-14 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：AIM:To assess the rate of infection, appropriateness of antimicrobial-therapy and mortality on intensive care unit (ICU). Special focus was drawn on patients with liver cirrhosis. METHODS:The study was approved by the local ethical committee. All patients admitted to the Internal Medicine-ICU between April 1, 2007 and...

journal_title：World journal of gastroenterology

authors： Friedrich-Rust M,Wanger B,Heupel F,Filmann N,Brodt R,Kempf VA,Kessel J,Wichelhaus TA,Herrmann E,Zeuzem S,Bojunga J

更新日期：2016-04-28 00:00:00

abstract：:Cytokines are indispensable signals of the mucosa-associated immune system for maintaining normal gut homeostasis. An imbalance of their profile in favour of inflammation initiation may lead to disease states, such as that is observed in inflammatory bowel diseases (IBD). Although Crohn's disease (CD) is often describ...

journal_title：World journal of gastroenterology

authors： Műzes G,Molnár B,Tulassay Z,Sipos F

更新日期：2012-11-07 00:00:00

abstract：:Pancreatic cancer is one of the most aggressive and difficult cancers to treat. Despite numerous research efforts, limited success has been achieved in the therapeutic management of patients with this disease. In the current review, we focus on one component of morphogenesis signaling, Hedgehog (Hh), with the aim of d...

journal_title：World journal of gastroenterology

authors： Onishi H,Katano M

更新日期：2014-03-07 00:00:00

abstract：:Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postopera...

journal_title：World journal of gastroenterology

authors： Zhang GF,Chai Y,Li WS,Huang LS,Shen G

更新日期：2014-09-21 00:00:00

abstract：:Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). T...

journal_title：World journal of gastroenterology

authors： Tomimaru Y,Nagano H,Marubashi S,Kobayashi S,Eguchi H,Takeda Y,Tanemura M,Kitagawa T,Umeshita K,Hashimoto N,Yoshikawa H,Wakasa K,Doki Y,Mori M

更新日期：2009-09-07 00:00:00

abstract：AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors rela...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Kim YJ,Kim SK

更新日期：2004-03-01 00:00:00

abstract：AIM:To investigate the effects and mechanisms of melatonin on immunological liver injury in mice. METHODS:A model of liver injury was induced by tail vein injection of Bacillus Calmette Guerin (BCG) and lipopolysaccharide (LPS) in mice. Kupffer cells and hepatocytes were isolated and cultured according to a modified t...

journal_title：World journal of gastroenterology

authors： Wang H,Wei W,Shen YX,Dong C,Zhang LL,Wang NP,Yue L,Xu SY

更新日期：2004-09-15 00:00:00

abstract：BACKGROUND:The introduction of biologics has revolutionized the management of the chronic inflammatory bowel disease, ulcerative colitis (UC), with many patients experiencing significant improvements not only in their symptoms but in other outcomes relevant to individuals and society as a whole. In Germany, there are n...

journal_title：World journal of gastroenterology

authors： Teich N,Grümmer H,Jörgensen E,Liceni T,Holtkamp-Endemann F,Fischer T,Hohenberger S

更新日期：2020-06-07 00:00:00

abstract：AIM:To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901. METHODS:Cell counts and MTT assay were used to quantify the influence of Nimesulide in the proliferation of SGC7901 cells. Transmission electron microscopy and flow cyt...

journal_title：World journal of gastroenterology

authors： Li JY,Wang XZ,Chen FL,Yu JP,Luo HS

更新日期：2003-05-01 00:00:00

abstract：AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specific to 16S rRNA of Helicobacter spp. was performed on paraffin-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The sample...

journal_title：World journal of gastroenterology

authors： Karagin PH,Stenram U,Wadström T,Ljungh A

更新日期：2010-10-14 00:00:00

abstract：AIM:To evaluate the usefulness of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) in differentiating between pancreatic adenocarcinomas and other pancreatic disease. METHODS:This retrospective cohort study evaluated 90 patients who were seen between November 2010 and May 2013. All these patients had solid pa...

journal_title：World journal of gastroenterology

authors： Park JS,Kim HK,Bang BW,Kim SG,Jeong S,Lee DH

更新日期：2014-01-14 00:00:00

abstract：:Acute pancreatitis constitutes 3% of all admissions with abdominal pain. There are reports of osteal fat necrosis leading to periosteal reactions and osteolytic lesions following severe pancreatitis, particularly in long bones. A 54-year-old man was admitted to our hospital with acute pancreatitis, who later developed...

journal_title：World journal of gastroenterology

authors： Muthukumarasamy G,Shanmugam V,Yule SR,Ravindran R

更新日期：2007-07-21 00:00:00

abstract：AIM:To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI) imaging as a noninvasive method for the assessment of liver fibrosis in chronic hepatitis C (CHC) patients. METHODS:We performed a prospective blind comparison of ARFI elastography, APRI index and FibroMax in a consecutive series of ...

journal_title：World journal of gastroenterology

authors： Fierbinteanu-Braticevici C,Andronescu D,Usvat R,Cretoiu D,Baicus C,Marinoschi G

更新日期：2009-11-28 00:00:00

abstract：:Ischemia/reperfusion (I/R) injury still represents an important cause of morbidity following hepatic surgery and limits the use of marginal livers in hepatic transplantation. Transient blood flow interruption followed by reperfusion protects tissues against damage induced by subsequent I/R. This process known as ische...

journal_title：World journal of gastroenterology

authors： Alchera E,Dal Ponte C,Imarisio C,Albano E,Carini R

更新日期：2010-12-28 00:00:00

abstract：AIM:It has been reported that regular consumption of nonsteroidal anti-inflammatory drugs like indomethacin decreases the incidence and mortality rate of a number of gastrointestinal cancers. We aimed to explore the efficacy and possible mechanisms of indomethacin on tumor growth and tumor angiogenesis of human colon c...

journal_title：World journal of gastroenterology

authors： Wang HM,Zhang GY

更新日期：2005-01-21 00:00:00

abstract：:Colorectal cancer (CRC) represents one of the leading causes of tumor-related deaths worldwide. Among the various tools at physicians' disposal for the diagnostic management of the disease, tomographic imaging (e.g., CT, MRI, and hybrid PET imaging) is considered essential. The qualitative and subjective evaluation of...

journal_title：World journal of gastroenterology

authors： Mainenti PP,Stanzione A,Guarino S,Romeo V,Ugga L,Romano F,Storto G,Maurea S,Brunetti A

更新日期：2019-09-21 00:00:00

abstract：:The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently been approved for this disease, response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment ...

journal_title：World journal of gastroenterology

authors： Wich C,Agaimy A,Strobel D,Wissniowski TT,Hartmann A,Ocker M

更新日期：2010-07-28 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：AIM:To investigate the association of nuclear morphometry and DNA content with resectability of pancreatic cancer. METHODS:A total of 36 patients with pancreatic adenocarcinoma were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of tumor cells were analyzed by IBAS autoi...

journal_title：World journal of gastroenterology

authors： He YC,Peng W,Qiao JG,Cao J,Chen JW

更新日期：2003-08-01 00:00:00

abstract：:The role of whole-body FDG [((18)F) 2-fluoro-2-deoxyglucose] positron emission tomography (PET) scanning as an imaging modality in the management of patients with malignancy has evolved enormously over the past two decades. FDG-PET has demonstrated significant efficacy in the staging, prognostication and detection of ...

journal_title：World journal of gastroenterology

authors： Smyth EC,Shah MA

更新日期：2011-12-14 00:00:00

abstract：AIM:To retrospectively analyze the fields of application, diagnostic yields and findings of OMOM capsule endoscopy in Chinese patients. METHODS:A database including 2400 Chinese patients who received OMOM capsule endoscopy in 27 endoscopy centers in China was retrieved from the Jianshan Science and Technology Ltd. OMO...

journal_title：World journal of gastroenterology

authors： Liao Z,Gao R,Li F,Xu C,Zhou Y,Wang JS,Li ZS

更新日期：2010-06-07 00:00:00

abstract：AIM:To prepare the chitosan-pmEpo nanoparticles and to study their ability for transcellular and paracellular transport across intestinal epithelia by oral administration. METHODS:ICR mice were fed with recombinant plasmid AAV-tetO-CMV-mEpo (containing mEpo gene) or pCMVbeta(containing LacZ gene), whether it was wrapp...

journal_title：World journal of gastroenterology

authors： Chen J,Yang WL,Li G,Qian J,Xue JL,Fu SK,Lu DR

更新日期：2004-01-01 00:00:00

abstract：AIM:To investigate the association between thrombocytopenia and relapse after treatment for hepatocellular carcinoma (HCC). METHODS:We searched the PubMed, EMBASE, and Web of Science databases to obtain eligible studies. The hazard ratios (HRs) values and 95% confidence intervals (CIs) were pooled by random effects mo...

journal_title：World journal of gastroenterology

authors： Pang Q,Qu K,Bi JB,Liu SS,Zhang JY,Song SD,Lin T,Xu XS,Wan Y,Tai MH,Liu HC,Dong YF,Liu C

更新日期：2015-07-07 00:00:00