Induction of CD69 expression by cagPAI-positive Helicobacter pylori infection.

abstract：AIM:To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. METHODS:In this study, 102 UC patients (53 Han including 22 men and 31 women, and 49 Uyghur patients including 25 men and 24 women; aged 48.07 ± 15.83...

journal_title：World journal of gastroenterology

authors： Aheman A,Gao F,Kuerbanjiang A,Li YX,Abuduhadeer M

更新日期：2013-05-07 00:00:00

abstract：BACKGROUND:Systemic inflammation and nutrition status play an important role in cancer metastasis. The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), consisting of haemoglobin, albumin, lymphocytes, and platelets, is considered as a novel marker to reflect both systemic inflammation and nutriti...

journal_title：World journal of gastroenterology

authors： Xu SS,Li S,Xu HX,Li H,Wu CT,Wang WQ,Gao HL,Jiang W,Zhang WH,Li TJ,Ni QX,Liu L,Yu XJ

更新日期：2020-02-28 00:00:00

abstract：AIM:To evaluate whether alcohol dehydrogenase-1B (ADH1B) His47Arg and aldehyde dehydrogenase-2 (ALDH2) Glu487Lys polymorphism is involved in the esophageal squamous cell carcinoma (ESCC) risk in Chinese Han population. METHODS:Seven studies of ADH1B and ALDH2 genotypes in Chinese Han population in 1450 cases and 2459 ...

journal_title：World journal of gastroenterology

authors： Zhang GH,Mai RQ,Huang B

更新日期：2010-12-21 00:00:00

abstract：:One 63-year-old woman, who presented with cholestatic jaundice due to common bile duct compression produced by primary retroperitoneal fibrosis, is studied. The patient was operated six years ago because of hydronephrosis, when the disease was first diagnosed. Magnetic resonance cholangiopancreatography (MRCP) reveale...

journal_title：World journal of gastroenterology

authors： Zhao MF,Tian Y,Guo KJ,Ma ZG,Liao HH

更新日期：2004-10-15 00:00:00

abstract：AIM:To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS:1H-MRS was performed in 18 rabbits using a 1.5T GE MR system with an eight-channel head/neck receiving coil. Fifteen rabbits were in...

journal_title：World journal of gastroenterology

authors： Shen ZW,Cao Z,You KZ,Yang ZX,Xiao YY,Cheng XF,Chen YW,Wu RH

更新日期：2012-03-14 00:00:00

abstract：AIM:To evaluate the effect of gastrectomy on diabetes mellitus (DM) and hypertension (HTN) in non-obese gastric cancer patients. METHODS:A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and ...

journal_title：World journal of gastroenterology

authors： Lee EK,Kim SY,Lee YJ,Kwak MH,Kim HJ,Choi IJ,Cho SJ,Kim YW,Lee JY,Kim CG,Yoon HM,Eom BW,Kong SY,Yoo MK,Park JH,Ryu KW

更新日期：2015-01-28 00:00:00

abstract：:Extraintestinal manifestations of inflammatory bowel disease (IBD) are a systemic illness that may affect up to half of all patients. Among the extraintestinal manifestations of IBD, those involving the lungs are relatively rare and often overlooked. However, there is a wide array of such manifestations, spanning from...

journal_title：World journal of gastroenterology

authors： Ji XQ,Wang LX,Lu DG

更新日期：2014-10-07 00:00:00

abstract：AIM:To investigate the effect of Chaiqinchengqi decoction (CQCQD) on sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissues in acute pancreatitis (AP) rats. METHODS:Thirty Sprague-Dawley (SD) rats were randomized into control group, AP group and CQCQD group (n = 3 x 10). The rats in the ...

journal_title：World journal of gastroenterology

authors： Xue P,Deng LH,Zhang ZD,Yang XN,Xia Q,Xiang DK,Huang L,Wan MH

更新日期：2008-04-21 00:00:00

abstract：:The normal esophageal mucosa creates a protective epithelial barrier that constrains the acidic reflux in the esophageal lumen. Microscopic findings and functional studies indicate that this barrier might be impaired in patients with non erosive reflux disease (NERD) but not in patients with functional heartburn (FH)....

journal_title：World journal of gastroenterology

authors： Triantos C,Koukias N,Karamanolis G,Thomopoulos K

更新日期：2015-05-21 00:00:00

abstract：AIM:To identify a small, clinically applicable immunohistochemistry (IHC) panel that could be combined with magnetic resonance imaging (MRI)-detected extramural vascular invasion (EMVI) for assessment of prognosis concerning the non-advanced rectal cancer patients prior to operation. METHODS:About 329 patients with pa...

journal_title：World journal of gastroenterology

authors： Li XF,Jiang Z,Gao Y,Li CX,Shen BZ

更新日期：2016-10-14 00:00:00

abstract：AIM:To investigate oxaliplatin-induced severe anaphylactic reactions (SAR) in metastatic colorectal cancer in a retrospective case series analysis and to conduct a systemic literature review. METHODS:During a 6-year period from 2006 to 2011 at Kaohsiung Veterans General Hospital, a total of 412 patients exposed to oxa...

journal_title：World journal of gastroenterology

authors： Wang JH,King TM,Chang MC,Hsu CW

更新日期：2012-10-14 00:00:00

abstract：AIM:To evaluate if 3 mo oral supplementation with Eviendep® was able to reduce the number of duodenal polyps in familial adenomatous polyposis (FAP) patients with ileal pouch-anal anastomosis (IPAA). METHODS:Eleven FAP patients with IPAA and duodenal polyps were enrolled. They underwent upper gastrointestinal (GI) end...

journal_title：World journal of gastroenterology

authors： Calabrese C,Praticò C,Calafiore A,Coscia M,Gentilini L,Poggioli G,Gionchetti P,Campieri M,Rizzello F

更新日期：2013-09-14 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：AIM:To investigate the role of transforming growth factor (TGF)-β-inducible early gene 1 (TIEG1) in TGF-β-induced growth inhibition in hepatocellular carcinoma (HCC) cells. METHODS:Human hepatocyte and HCC cell lines with varied susceptibilities to TGF-β1 were tested by methylthiazoletetrazolium (MTT) assay. The expre...

journal_title：World journal of gastroenterology

authors： Jiang L,Lai YK,Zhang JF,Chan CY,Lu G,Lin MC,He ML,Li JC,Kung HF

更新日期：2012-05-07 00:00:00

abstract：:Intratumoral heterogeneity including genetic and nongenetic mechanisms refers to biological differences amongst malignant cells originated within the same tumor. Both, cell differentiation hierarchy and stochasticity in gene expression and signaling pathways may result in phenotypic differences of cancer cells. Since ...

journal_title：World journal of gastroenterology

authors： Sipos F,Constantinovits M,Műzes G

更新日期：2014-03-14 00:00:00

abstract：AIM:To investigate if non-peptidic small molecular inhibitors of the p53-HDM2 interaction could restore p53 function and kill tumor cells. METHODS:A series of non-peptidic small HDM2 inhibitors were designed by computer-aided model and synthesized by chemical method. Syl-155 was one of these inhibitors. Cytotoxic effe...

journal_title：World journal of gastroenterology

authors： Li WD,Wang MJ,Ding F,Yin DL,Liu ZH

更新日期：2005-05-21 00:00:00

abstract：AIM:To study the role of gastric mucosal ascorbic acid (AA) in the progression of acute gastric mucosal lesions induced by compound 48/80 (C48/80), a mast cell degranulator, in rats. METHODS:C48/80 (0.75 mg/kg) was intraperitoneally injected to fasted Wistar rats. Oral administration of AA (10, 50 or 100 mg/kg) was pe...

journal_title：World journal of gastroenterology

authors： Kamiya Y,Ohta Y,Imai Y,Arisawa T,Nakano H

更新日期：2005-03-07 00:00:00

abstract：AIM:To investigate the protective effect and mechanism of rebamipide on small intestinal permeability induced by diclofenac in mice. METHODS:Diclofenac (2.5 mg/kg) was administered once daily for 3 d orally. A control group received the vehicle by gavage. Rebamipide (100 mg/kg, 200 mg/kg, 400 mg/kg) was administered i...

journal_title：World journal of gastroenterology

authors： Diao L,Mei Q,Xu JM,Liu XC,Hu J,Jin J,Yao Q,Chen ML

更新日期：2012-03-14 00:00:00

abstract：AIM:To explore risk factors for lymph node metastases in early gastric cancer (EGC) and to confirm the appropriate range of lymph node dissection. METHODS:A total of 202 patients with EGC who underwent curative gastrectomy with lymphadenectomy in the Department of Surgery, Xinhua Hospital and Ruijin Hospital of Shangh...

journal_title：World journal of gastroenterology

authors： Ren G,Cai R,Zhang WJ,Ou JM,Jin YN,Li WH

更新日期：2013-05-28 00:00:00

abstract：:Colorectal cancer is a major cause of cancer-related death in many countries. Colorectal carcinogenesis is a stepwise process which, from normal mucosa leads to malignancy. Many factors have been shown to influence this process, however, at present, several points remain obscure. In recent years some hypotheses have b...

journal_title：World journal of gastroenterology

authors： Mariani F,Sena P,Roncucci L

更新日期：2014-08-07 00:00:00

abstract：AIM:To assess the clinical outcomes of pre-, pro- and synbiotics therapy in patients with acute pancreatitis. METHODS:The databases including Medline, Embase, the Cochrane Library, Web of Science and Chinese Biomedicine Database were searched for all relevant randomized controlled trials that studied the effects of pr...

journal_title：World journal of gastroenterology

authors： Zhang MM,Cheng JQ,Lu YR,Yi ZH,Yang P,Wu XT

更新日期：2010-08-21 00:00:00

abstract：AIM:To determine whether circular RNAs (circRNAs) are involved in pathological processes of gastric cancer (GC). METHODS:Three circRNAs with differential expression in GC and colorectal cancer were randomly selected for validation by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), using 20 pair...

journal_title：World journal of gastroenterology

authors： Huang M,He YR,Liang LC,Huang Q,Zhu ZQ

更新日期：2017-09-14 00:00:00

abstract：AIM:To investigate the distribution pattern of lymphatic vessels and microvessels in sporadic colorectal carcinoma (SCRC) and their relationship to metastasis and prognosis. METHODS:The lymphatic vessel density (LVD) and microvessel density (MVD) in tumor tissue obtained from 132 patients with primary SCRC, including ...

journal_title：World journal of gastroenterology

authors： Yan G,Zhou XY,Cai SJ,Zhang GH,Peng JJ,Du X

更新日期：2008-01-07 00:00:00

abstract：AIM:To determine the association of human antigen R (HuR) and inhibitors of apoptosis proteins (IAP1, IAP2) and prognosis in pancreatic cancer. METHODS:Protein and mRNA expression levels of IAP1, IAP2 and HuR in pancreatic ductal adenocarcinoma (PDAC) were compared with normal pancreatic tissue. The correlations among...

journal_title：World journal of gastroenterology

authors： Lukosiute-Urboniene A,Jasukaitiene A,Silkuniene G,Barauskas V,Gulbinas A,Dambrauskas Z

更新日期：2019-01-14 00:00:00

abstract：AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

journal_title：World journal of gastroenterology

authors： Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

更新日期：2008-11-14 00:00:00

abstract：:We report a case of intraductal papillary neoplasm of the bile duct (IPNB) that developed in a patient with primary sclerosing cholangitis. A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels. Computed tomography showed d...

journal_title：World journal of gastroenterology

authors： Hachiya H,Kita J,Shiraki T,Iso Y,Shimoda M,Kubota K

更新日期：2014-11-14 00:00:00

abstract：AIM:To summarize progress in the study of K-ras gene studies in pancreatic cancer and its potential clinical significance in screening test for early detection of pancreatic cancer, and to differentiate pancreatic cancer from chronic pancreatitis in recent decade. METHODS:Literature search (MEDLINE 1986-2003) was perf...

journal_title：World journal of gastroenterology

authors： Mu DQ,Peng YS,Xu QJ

更新日期：2004-02-15 00:00:00

abstract：AIM:To examine the association between obesity-related adipokines (adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) and colorectal cancer (CRC) risk. METHODS:Serum levels of adipokines were measured in 100 CRC patients and age- and sex-matched controls for the data analysis. Unc...

journal_title：World journal of gastroenterology

authors： Joshi RK,Kim WJ,Lee SA

更新日期：2014-06-28 00:00:00

abstract：AIM:To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients. METHODS:We evaluated the methylation status of 2 genes (SLIT2 and TGFB2) in 226 biopsies taken from 62 colonoscopies of 38 patients (29 ulcerative colitis...

journal_title：World journal of gastroenterology

authors： Lobatón T,Azuara D,Rodríguez-Moranta F,Loayza C,Sanjuan X,de Oca J,Fernández-Robles A,Guardiola J,Capellá G

更新日期：2014-08-14 00:00:00

abstract：AIM:To discuss the expression of human leukocyte antigen (HLA) class I antigens in gastric cancer and correlate these with pathologic type and TNM stage. METHODS:The expression of HLA class I antigen was detected by immunohistochemistry in 185 specimens of gastric cancer, 20 gastric cancer specimens with lymphatic met...

journal_title：World journal of gastroenterology

authors： Shen YQ,Zhang JQ,Miao FQ,Zhang JM,Jiang Q,Chen H,Shan XN,Xie W

更新日期：2005-06-21 00:00:00