MicroRNA-185-5p mediates regulation of SREBP2 expression by hepatitis C virus core protein.

abstract：AIM:To study the role of P38 kinase in esophageal cancer cell apoptosis induced by genotoxin, cisplatin and the unfolded protein response (UPR) inducer, dithiothreitol (DTT). METHODS:Esophageal carcinoma cell line Eca109 was cultured in RPMI 1640 medium to 70% confluency and treated with either cisplatin, DTT, or cisp...

journal_title：World journal of gastroenterology

authors： Zhang QX,Feng R,Zhang W,Ding Y,Yang JY,Liu GH

更新日期：2005-08-07 00:00:00

abstract：AIM:To investigate the effects of Terminalia arjuna (T. arjuna) extract on human hepatoma cell line (HepG2) and its possible role in induction of apoptosis. METHODS:Human hepatoma cells were treated with different concentrations of ethanolic extract of T. arjuna and its cytotoxicity effect was measured by trypan blue ...

journal_title：World journal of gastroenterology

authors： Sivalokanathan S,Vijayababu MR,Balasubramanian MP

更新日期：2006-02-21 00:00:00

abstract：AIM:To investigate the effect of APOBEC3G mediated antiviral activity against hepatitis B virus (HBV) in cell cultures and replication competent HBV vector-based mouse model. METHODS:The mammalian hepatoma cells Huh7 and HepG2 were cotransfected with various amounts of CMV-driven expression vector encoding APOBEC3G an...

journal_title：World journal of gastroenterology

authors： Lei YC,Hao YH,Zhang ZM,Tian YJ,Wang BJ,Yang Y,Zhao XP,Lu MJ,Gong FL,Yang DL

更新日期：2006-07-28 00:00:00

abstract：:Desmoid tumor is a locally invasive, myofibroblastic, nonmetastatic tumor. Its pathogenesis remains unclear and it may involve genetic abnormalities, sex hormones and traumatic injury, including surgery. Postoperative intra-abdominal desmoid tumor is rare, especially in the retroperitoneum. We report a case of postope...

journal_title：World journal of gastroenterology

authors： Shih LY,Wei CK,Lin CW,Tseng CE

更新日期：2012-11-14 00:00:00

abstract：AIM:To investigate Fusobacterium nucleatum (F. nucleatum) abundance in colorectal cancer (CRC) tissues and its association with CRC invasiveness in Chinese patients. METHODS:The resected cancer and adjacent normal tissues (10 cm beyond cancer margins) from 101 consecutive patients with CRC were collected. Fluorescent ...

journal_title：World journal of gastroenterology

authors： Li YY,Ge QX,Cao J,Zhou YJ,Du YL,Shen B,Wan YJ,Nie YQ

更新日期：2016-03-21 00:00:00

abstract：AIM:To investigate the utility of K-ras mutation analysis of ultrasound guided fine-needle aspirate biopsy of pancreatic masses. METHODS:Sixty-six ultrasound guided fine-needle biopsies were evaluated by cytology, histology and k-ras mutation. The mutation at codon 12 of the k-ras oncogene was detected by artificial r...

journal_title：World journal of gastroenterology

authors： Zheng M,Liu LX,Zhu AL,Qi SY,Jiang HC,Xiao ZY

更新日期：2003-01-01 00:00:00

abstract：AIM:To investigate the effect of Chaiqinchengqi decoction (CQCQD) on sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissues in acute pancreatitis (AP) rats. METHODS:Thirty Sprague-Dawley (SD) rats were randomized into control group, AP group and CQCQD group (n = 3 x 10). The rats in the ...

journal_title：World journal of gastroenterology

authors： Xue P,Deng LH,Zhang ZD,Yang XN,Xia Q,Xiang DK,Huang L,Wan MH

更新日期：2008-04-21 00:00:00

abstract：BACKGROUND:Laparoscopy has been widely used in general surgical procedures, but total laparoscopic pancreaticoduodenectomy (TLPD) is still a complex and challenging surgery that is only performed in a small number of patients at a few large academic medical centers. Although the safety and feasibility of TLPD have been...

journal_title：World journal of gastroenterology

authors： Zhang H,Lan X,Peng B,Li B

更新日期：2019-10-07 00:00:00

abstract：:Acute pancreatitis is an inflammatory disorder of the pancreas that may cause life-threatening complications. Etiologies of pancreatitis vary, with gallstones accounting for the majority of all cases, followed by alcohol. Other causes of pancreatitis include trauma, ischemia, mechanical obstruction, infections, autoim...

journal_title：World journal of gastroenterology

authors： Binker MG,Cosen-Binker LI

更新日期：2014-05-21 00:00:00

abstract：:In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC, it failed in patients with Crohn's disease (CD). This finding strongly hints at a different contribution of JAK signaling in both ...

journal_title：World journal of gastroenterology

authors： Cordes F,Foell D,Ding JN,Varga G,Bettenworth D

更新日期：2020-07-28 00:00:00

abstract：AIM:To describe the bowel habits and the prevalence of irritable bowel syndrome (IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS:This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between F...

journal_title：World journal of gastroenterology

authors： Costanian C,Tamim H,Assaad S

更新日期：2015-03-28 00:00:00

abstract：AIM:To investigate the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in gastric carcinoma and its clinical significance and to explore its relationship with cell proliferation. METHODS:Expressions of IGFBP-2 and Ki-67 in 118 cases of gastric carcinoma and 40 cases of normal gastric mucosa were d...

journal_title：World journal of gastroenterology

authors： Shi LH,Zhu XQ,Zhao GH,Xia YB,Zhang YS

更新日期：2006-10-21 00:00:00

abstract：AIM:To investigate the antibacterial effects of a crude extract of maggots against Escherichia coli (E. coli) and the underlying mechanisms, and to separate and purify the crude extract of maggots to assess the antibacterial effects of the active ingredients in the crude extract. METHODS:Different concentrations of th...

journal_title：World journal of gastroenterology

authors： Ge QS,Zhang HM,Liu X,Wang SY,Lv DC,Li XD

更新日期：2015-02-07 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：:Despite that some approved drugs and genetically engineered vaccines against hepatitis B virus (HBV) are available for HBV patients, HBV infection is still a severe public health problem in the world. All the approved therapeutic drugs (including interferon-alpha and nucleoside analogues) have their limitations. No dr...

journal_title：World journal of gastroenterology

authors： Wu YH

更新日期：2016-01-07 00:00:00

abstract：:Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor (GIST) in the stomach is uncommon. Only rare cases have been reported in the literature. We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22...

journal_title：World journal of gastroenterology

authors： Mou YP,Xu XW,Xie K,Zhou W,Zhou YC,Chen K

更新日期：2010-10-21 00:00:00

abstract：:Port site hernia develops through a fascial or peritoneal layer that was inadequate or not repaired. It is a rare complication of laparoscopic surgery which may lead to serious problems. Here, we present a 77-year-old female, diagnosed with a small bowel hernia through a 10-mm port site. We had performed ten cases of ...

journal_title：World journal of gastroenterology

authors： Lee JH,Kim W

更新日期：2008-11-28 00:00:00

abstract：AIM:To investigate the inhibitory effect of in vivo expression of expressing plasmid pCH510 of recombinant fibronectin polypeptide (CH50) on hepatocellular carcinoma and the improved therapeutic effect of pCH510 in combination with chemotherapeutic agents and Hsp70-H22 hepatocarcinoma antigen peptide on tumor. METHODS...

journal_title：World journal of gastroenterology

authors： Zhang GM,Yang Y,Huang B,Xiao H,Li D,Feng ZH

更新日期：2003-09-01 00:00:00

abstract：:Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. A 56-year-old Caucasian male was admitted to our surgical department with a chief complaint of a painful mass in his right lower abdomen for almost 2 years. The physical examinati...

journal_title：World journal of gastroenterology

authors： Wang TB,Dai WG,Liu DW,Shi HP,Dong WG

更新日期：2013-10-21 00:00:00

abstract：:Hepatic encephalopathy (HE) is a neuropsychiatric complication of cirrhosis or acute liver failure. Currently, HE is regarded as a continuous cognitive impairment ranging from the mildest stage, minimal HE to overt HE. Hyperammonaemia and neuroinflammation are two main underlying factors which contribute to the neurol...

journal_title：World journal of gastroenterology

authors： Zhang XD,Zhang LJ,Wu SY,Lu GM

更新日期：2014-08-28 00:00:00

abstract：AIM:To examine the role of microRNA 1181 (miR-1181) in invasion and proliferation in pancreatic cancer. METHODS:We analyzed the expression of miR-1181 in several pancreatic cancer cell lines and generated stable MIA-PaCa-2 and PANC-1 cell lines with up-regulated miR-1181 expression using an adenovirus delivery system....

journal_title：World journal of gastroenterology

authors： Wang J,Guo XJ,Ding YM,Jiang JX

更新日期：2017-03-07 00:00:00

abstract：AIM:To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome. METHODS:Purified anti-CEA monoclonal antibody (McAb) was biotinylated with NHS-biotin, and then radiolabeled with 188Re by the direct method. 188Re-labeled b...

journal_title：World journal of gastroenterology

authors： Li GP,Wang YX,Huang K,Zhang H,Zhang CF

更新日期：2005-04-07 00:00:00

abstract：AIM:To systematically review literature addressing three key psychologically-oriented controversies associated with gastroparesis. METHODS:A comprehensive search of PubMed, CINAHL, and PsycINFO databases was performed to identify literature addressing the relationship between gastroparesis and psychological factors. T...

journal_title：World journal of gastroenterology

authors： Woodhouse S,Hebbard G,Knowles SR

更新日期：2017-02-21 00:00:00

abstract：AIM:To establish a new, reliable vomit model of minks. METHODS:Adult male minks were randomly divided into 8 groups (n=6): cisplatin (7.5 mg/kg) intraperitoneal injection (i.p.) group, copper sulfate (40 mg/kg) intragastric injection (i.g.) group, apomorphine (1.6 mg/kg) subcutaneous injection (s.c.) group, and 18 Gy ...

journal_title：World journal of gastroenterology

authors： Zhang F,Wang L,Yang ZH,Liu ZT,Yue W

更新日期：2006-02-28 00:00:00

abstract：:Colorectal cancer (CRC) is one of the commonest cancers with 1.2 million new cases diagnosed each year in the world. It remains the fourth most common cause of cancer-related mortality in the world and accounts for > 600000 cancer-related deaths each year. There have been significant advances in treatment of metastati...

journal_title：World journal of gastroenterology

authors： Khan K,Wale A,Brown G,Chau I

更新日期：2014-09-21 00:00:00

abstract：AIM:To investigate the association between babA2 gene and peptic ulcer disease (PUD) and gastric cancer (GC) in Helicobacter pylori-infected populations. METHODS:We evaluated the relationship between babA2 and clinical outcomes (PUD and GC) using a meta-analysis. A literature search was performed using the PubMed and ...

journal_title：World journal of gastroenterology

authors： Chen MY,He CY,Meng X,Yuan Y

更新日期：2013-07-14 00:00:00

abstract：AIM:To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS:A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclat...

journal_title：World journal of gastroenterology

authors： Hayes SJ,Hng KN,Clark P,Thistlethwaite F,Hawkins RE,Ang Y

更新日期：2014-04-14 00:00:00

abstract：:Some viruses, including certain members of the enterovirus genus, have been reported to cause pancreatitis, especially Coxsackie virus. However, no case of human enterovirus 71 (EV71) associated with pancreatitis has been reported so far. We here report a case of EV71-induced hand-foot-and-mouth disease (HFMD) present...

journal_title：World journal of gastroenterology

authors： Zhang YF,Deng HL,Fu J,Zhang Y,Wei JQ

更新日期：2016-02-14 00:00:00

abstract：AIM:To examine whether high-flow nasal oxygen (HFNO) availability influences the use of general anesthesia (GA) in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) and associated outcomes. METHODS:In this retrospective study, patients were stratified into 3 eras...

journal_title：World journal of gastroenterology

authors： Schumann R,Natov NS,Rocuts-Martinez KA,Finkelman MD,Phan TV,Hegde SR,Knapp RM

更新日期：2016-12-21 00:00:00

abstract：AIM:To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate. METHODS:Dexamethasone cholesteryl butyrate-solid lipid nanoparticles (DxCb-SLN) were obtained with the warm microemulsion method. The anti-inflammatory activity of this novel nanofor...

journal_title：World journal of gastroenterology

authors： Dianzani C,Foglietta F,Ferrara B,Rosa AC,Muntoni E,Gasco P,Della Pepa C,Canaparo R,Serpe L

更新日期：2017-06-21 00:00:00