Alanine aminotransferase is an inadequate surrogate marker for detecting lamivudine resistance.

abstract：AIM:To investigate the existence and clinical significance of hepatitis C virus (HCV) RNA in the serum and peripheral blood mononuclear cells (PBMC) of patients with hepatitis C. METHODS:HCV RNA was detected by nested polymerase chain reaction (Nested PCR) in serum and in PBMC of 46 patients with acute hepatitis C (AH...

journal_title：World journal of gastroenterology

authors： Zhou P,Cai Q,Chen YC,Zhang MS,Guan J,Li XJ

更新日期：1997-06-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide. The majority of HCC cases occur in patients with chronic liver disease. Despite regular surveillance to detect small HCC in these patients, HCC is often diagnosed at an advanced stage. Because HCC is highly resistant to conventional systemic ...

journal_title：World journal of gastroenterology

authors： Shin JW,Chung YH

更新日期：2013-10-07 00:00:00

abstract：AIM:To test the hypothesis that enhancement of the activity of heme oxygenase can interfere with processes of fibrogenesis associated with recurrent liver injury, we investigated the therapeutic potential of over-expression of heme oxygense-1 in a CCl(4)-induced micronodular cirrhosis model. METHODS:Recombinant adeno-...

journal_title：World journal of gastroenterology

authors： Tsui TY,Lau CK,Ma J,Glockzin G,Obed A,Schlitt HJ,Fan ST

更新日期：2006-04-07 00:00:00

abstract：AIM:To evaluate the role of three-dimensional contrast-enhanced magnetic resonance angiography (3D CE MRA) in the diagnosis of Budd-Chiari syndrome (BCS). METHODS:Twenty-three patients with BCS underwent 3D CE MRA examination, in which 13 cases were secondary to either hepatocellular carcinoma (11 cases), right adrena...

journal_title：World journal of gastroenterology

authors： Lin J,Chen XH,Zhou KR,Chen ZW,Wang JH,Yan ZP,Wang P

更新日期：2003-10-01 00:00:00

abstract：:Recently, inflammatory bowel disease (IBD) has been the subject of considerable research, with increasing attention being paid to the loss of intestinal epithelial cell barrier function as a mechanism of pathogenesis. Ste20-related proline/alanine-rich kinase (SPAK) is involved in regulating barrier function. SPAK is ...

journal_title：World journal of gastroenterology

authors： Yan Y,Merlin D

更新日期：2008-10-28 00:00:00

abstract：AIM:To investigate the influence of the resection margin on local recurrence and survival in gastric cancer patients. METHODS:We reviewed the medical records of 1788 patients who had undergone gastrectomy for gastric cancer at the Seoul National University Bundang Hospital, South Korea, between May 2003 and July 2009....

journal_title：World journal of gastroenterology

authors： Lee CM,Jee YS,Lee JH,Son SY,Ahn SH,Park DJ,Kim HH

更新日期：2014-08-14 00:00:00

abstract：BACKGROUND:Treatments for hepatic sinusoidal obstruction syndrome (HSOS) are limited. AIM:To evaluate transjugular intrahepatic portosystemic shunting (TIPS) as a treatment for pyrrolidine alkaloid-related HSOS (PA-HSOS). METHODS:This retrospective analysis included patients with PA-HSOS admitted to the First Affilia...

journal_title：World journal of gastroenterology

authors： Zhou CZ,Wang RF,Lv WF,Fu YQ,Cheng DL,Zhu YJ,Hou CL,Ye XJ

更新日期：2020-06-28 00:00:00

abstract：AIM:To investigate the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in gastric carcinoma and its clinical significance and to explore its relationship with cell proliferation. METHODS:Expressions of IGFBP-2 and Ki-67 in 118 cases of gastric carcinoma and 40 cases of normal gastric mucosa were d...

journal_title：World journal of gastroenterology

authors： Shi LH,Zhu XQ,Zhao GH,Xia YB,Zhang YS

更新日期：2006-10-21 00:00:00

abstract：:A rare case of multiple small bowel ruptures due to ischemic enteritis (ISE) is reported. The patient was admitted to the hospital with acute abdominal pain followed by bloody diarrhoeas. Preoperative colonoscopic findings were similar to those presented in Crohn's disease. Intraoperatively, ischemic lesions and multi...

journal_title：World journal of gastroenterology

authors： Delikoukos S,Christodoulidis G,Zacharoulis D,Poultsidi A,Hatzitheofilou C

更新日期：2006-07-14 00:00:00

abstract：:The relationship between diabetes mellitus and the risk of pancreatic cancer has been a matter of study for a long period of time. The importance of this topic is due to two main causes: the possible use of recent onset diabetes as a marker of the disease and, in particular, as a specific marker of pancreatic cancer, ...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Pagano N

更新日期：2013-08-14 00:00:00

abstract：:Malignant gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating from the wall of the gastrointestinal tract. Their coexistence with other tumors originating from other germ layers is unique. We have reported a case of a 63-year-old GIST patient presenting as an epigastric mass associated with ...

journal_title：World journal of gastroenterology

authors： Jaworski R,Jastrzebski T,Swierblewski M,Drucis K,Kobierska-Gulida G

更新日期：2006-01-28 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the most common cause of hepatic fibrosis and hepatocellular carcinoma (HCC), mainly as a result of chronic necroinflammatory liver disease. A characteristic feature of chronic hepatitis B infection, alcoholic liver disease and nonalcoholic fatty liver disease (NAFLD) is he...

journal_title：World journal of gastroenterology

authors： Shimizu I,Kohno N,Tamaki K,Shono M,Huang HW,He JH,Yao DF

更新日期：2007-08-28 00:00:00

abstract：AIM:To investigate the mechanisms of aspirin increasing the susceptibility of Helicobacter pylori (H pylori) to metronidazole. METHODS:H pylori reference strain 26695 and two metronidazole-resistant isolates of H pylori were included in this study. Strains were incubated in Brucella broth with or without aspirin (1 mm...

journal_title：World journal of gastroenterology

authors： Zhang XP,Wang WH,Tian Y,Gao W,Li J

更新日期：2009-02-28 00:00:00

abstract：:Hereditary pancreatitis is an autosomal dominant condition, which results in recurrent attacks of acute pancreatitis, progressing to chronic pancreatitis often at a young age. The majority of patients with hereditary pancreatitis express one of two mutations (R122H or N29I) in the cationic trypsinogen gene (PRSS1 gene...

journal_title：World journal of gastroenterology

authors： Charnley RM

更新日期：2003-01-01 00:00:00

abstract：AIM:To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease (NAFLD). METHODS:Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose (400 mg) HL tablet, low dose (133.4 mg) ...

journal_title：World journal of gastroenterology

authors： Jeong JY,Sohn JH,Baek YH,Cho YK,Kim Y,Kim H

更新日期：2017-08-28 00:00:00

abstract：AIM:To investigate the prevalence and clinical significance of "anti-HBc alone" in an unselected population of patients and employees of a university hospital in southern Germany. METHODS:All individuals with the pattern "anti-HBc alone" were registered over a time span of 82 mo. HBV-DNA was measured in serum and live...

journal_title：World journal of gastroenterology

authors： Knöll A,Hartmann A,Hamoshi H,Weislmaier K,Jilg W

更新日期：2006-02-28 00:00:00

abstract：AIM:To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS:20 dogs of both sexes were used in this study. After laparotomy under anesthesia, 2 cm section of cecal end was clamped and ligated, then 1 cm cecum...

journal_title：World journal of gastroenterology

authors： Wang XC,Gui CQ,Zheng QS

更新日期：2003-03-01 00:00:00

abstract：:Left ventricular assist devices (LVAD) are increasingly become common as life prolonging therapy in patients with advanced heart failure. Current devices are now used as definitive treatment in some patients given the improved durability of continuous flow pumps. Unfortunately, continuous flow LVADs are fraught with c...

journal_title：World journal of gastroenterology

authors： Vedachalam S,Balasubramanian G,Haas GJ,Krishna SG

更新日期：2020-05-28 00:00:00

abstract：AIM:To evaluate the feasibility and utility of confocal laser endomicroscopy (CLE) in the description of normal gastrointestinal (GI) mucosa and in the diagnosis of GI disorders in children, in comparison to histology. METHODS:Forty-four patients (19 female) median age 10.9 years (range 0.7-16.6 years) with suspected ...

journal_title：World journal of gastroenterology

authors： Venkatesh K,Cohen M,Evans C,Delaney P,Thomas S,Taylor C,Abou-Taleb A,Kiesslich R,Thomson M

更新日期：2009-05-14 00:00:00

abstract：AIM:To evaluate the clinical outcomes of patients undergoing hepatectomy with hemihepatic vascular occlusion (HHO) compared with total hepatic inflow occlusion (THO). METHODS:Randomized controlled trials (RCTs) comparing hemihepatic vascular occlusion and total hepatic inflow occlusion were included by a systematic li...

journal_title：World journal of gastroenterology

authors： Wang HQ,Yang JY,Yan LN

更新日期：2011-07-14 00:00:00

abstract：AIM:To investigate the effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing radical distal gastrectomy. METHODS:Within 24 h of intensive care unit management, patients with gastric cancer were enrolled after written informed consent and randomize...

journal_title：World journal of gastroenterology

authors： Liu HC,Zhou YB,Chen D,Niu ZJ,Yu Y

更新日期：2012-06-07 00:00:00

abstract：AIM:To evaluate the significance of hsp90alpha expression in human gastric cancer tissues. METHODS:Immunohistochemical staining was used in clinical specimens from 33 cases of gastric cancer and 33 cases of gastritis with rabbit anti-human hsp90alpha multi-clonal antibody in order to explore the relationship between t...

journal_title：World journal of gastroenterology

authors： Zuo DS,Dai J,Bo AH,Fan J,Xiao XY

更新日期：2003-11-01 00:00:00

abstract：AIM:To investigate retrospectively the long-term effect of endoscopic sphincterotomy (ES) including exocrine pancreatic function in patients with stenosis of ampulla of Vater. METHODS:After diagnostic endoscopic retrograde cholangiopancreatography (ERCP) and ES because of stenosis of the ampulla of Vater (SOD Type I),...

journal_title：World journal of gastroenterology

authors： Ewald N,Marzeion AM,Bretzel RG,Kloer HU,Hardt PD

更新日期：2007-02-14 00:00:00

abstract：AIM:To establish the transgenic mouse line harbouring complete hepatitis B virus (HBV) genome with mutant s gene (adr subtype). METHODS:Transgenic mice were generated by microinjecting HBV genome into fertilized eggs. Integration, expression, replication of HBV gene and histological changes in transgenic mice were est...

journal_title：World journal of gastroenterology

authors： Ge JH,Zhang LZ,Li JX,Liu H,Liu HM,He J,Yao YC,Yang YJ,Yu HY,Hu YP

更新日期：2004-11-01 00:00:00

abstract：AIM:To determine the incidence of peripheral fractures in patients with celiac disease (CD) and the effect of treatment on fracture risk. METHODS:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with CD at least 5 years before...

journal_title：World journal of gastroenterology

authors： Sánchez MI,Mohaidle A,Baistrocchi A,Matoso D,Vázquez H,González A,Mazure R,Maffei E,Ferrari G,Smecuol E,Crivelli A,de Paula JA,Gómez JC,Pedreira S,Mauriño E,Bai JC

更新日期：2011-07-07 00:00:00

abstract：:Advances in molecular diagnostic tools have allowed the identification of lymph node micrometastasis (LNM), including isolated tumor cells, in cancer patients. While immunohistochemistry and reverse transcription-polymerase chain reaction have been used to identify LNM in patients with gastric cancer, the clinical sig...

journal_title：World journal of gastroenterology

authors： Sonoda H,Tani T

更新日期：2014-10-14 00:00:00

abstract：AIM:To investigate the role of heme oxygenase-1 (HO-1) in pathogenesis of experimental hepatorenal syndrome (HRS). METHODS:Rats were divided into liver cirrhotic group, zinc protoporphyrin IX (ZnPP) treatment group, cobalt protoporphyrin (CoPP) treatment group and sham group. Biliary cirrhosis was established by bile ...

journal_title：World journal of gastroenterology

authors： Guo SB,Duan ZJ,Li Q,Sun XY

更新日期：2011-01-21 00:00:00

abstract：AIM:To investigate the association of tumor necrosis factor alpha (TNFα) -G308A polymorphism with different liver pathological changes in treatment-naïve Egyptian patients infected with hepatitis C virus (HCV) genotype 4. METHODS:This study included 180 subjects, composed of 120 treatment-naïve chronic HCV patients wi...

journal_title：World journal of gastroenterology

authors： Bader El Din NG,Farouk S,El-Shenawy R,Ibrahim MK,Dawood RM,Elhady MM,Salem AM,Zayed N,Khairy A,El Awady MK

更新日期：2016-09-14 00:00:00

abstract：:The risk factors for hepatocellular carcinoma (HCC) development have been established, and include chronic hepatitis B and C, heavy alcohol consumption, and aflatoxins. In fact, 5%-30% of patients with HCC still lack a readily identifiable risk factor. It has been reported that the majority of ''cryptogenic'' HCC may ...

journal_title：World journal of gastroenterology

authors： Wang SN,Lee KT,Ker CG

更新日期：2010-12-14 00:00:00

abstract：AIM:To detect microsatellite instability (MSI) in patients with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer and to provide criteria for screening the kindreds with hereditary nonpolyposis colorectal cancer at molecular level. METHODS:MSI was detected in the specimens from 20 case...

journal_title：World journal of gastroenterology

authors： Liu WZ,Jin F,Zhang ZH,Wang SB

更新日期：2006-08-07 00:00:00