Is diabetes mellitus a risk factor for pancreatic cancer?

abstract：AIM:To evaluate the prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues. METHODS:A total of 5333 hepatitis B surface antigen-positive patients from the China Liver Transplant Registry database were enrolled between January 2000 and December 2009. Low-dose in...

journal_title：World journal of gastroenterology

authors： Shen S,Jiang L,Xiao GQ,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Xu MQ,Wei YG

更新日期：2015-01-14 00:00:00

abstract：AIM:To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS:p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by p21 promoter, and the...

journal_title：World journal of gastroenterology

authors： Gong GZ,Jiang YF,He Y,Lai LY,Zhu YH,Su XS

更新日期：2004-08-01 00:00:00

abstract：:Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

journal_title：World journal of gastroenterology

authors： Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

更新日期：2014-07-07 00:00:00

abstract：:To our knowledge, stercoral perforation of the colon is rarely seen with fewer than 90 cases reported in the literature till date. We explored the principles of management to prevent impending mortality in five patients with this condition. Five patients, two males and three females, whose median age was 64 years, had...

journal_title：World journal of gastroenterology

authors： Huang WS,Wang CS,Hsieh CC,Lin PY,Chin CC,Wang JY

更新日期：2006-01-21 00:00:00

abstract：AIM:To assess the use of topical negative pressure (TNP) in the management of severe peritonitis. METHODS:This is a four-year prospective analysis from January 2005 to December 2008 of 20 patients requiring TNP following laparotomy for severe peritonitis. RESULTS:There were 11 males with an average age of (59.3 +/- 3...

journal_title：World journal of gastroenterology

authors： Amin AI,Shaikh IA

更新日期：2009-07-21 00:00:00

abstract：AIM:To study the induction of T cellular immune responses in BALB/c mice immunized with uric acid and dendritic cells (DCs) pulsed with hepatitis B virus surface antigen (HBsAg). METHODS:DCs were generated from bone-marrow cells of BABL/c mice, and then pulsed or unpulsed with HBsAg protein (HBsAg-pulsed-DCs or unpuls...

journal_title：World journal of gastroenterology

authors： Ma XJ,Tian DY,Xu D,Yang DF,Zhu HF,Liang ZH,Zhang ZG

更新日期：2007-02-21 00:00:00

abstract：AIM:To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS:The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface anti...

journal_title：World journal of gastroenterology

authors： Kamijo N,Matsumoto A,Umemura T,Shibata S,Ichikawa Y,Kimura T,Komatsu M,Tanaka E

更新日期：2015-01-14 00:00:00

abstract：:Primary hepatic neuroendocrine tumor (PHNET) is an extremely rare liver tumor. Patients often have no clinical symptoms or have only non-specific symptoms, such as abdominal pain and abdominal mass. The clinical manifestations, disease development, treatment methods, and treatment outcomes of PHNET vary greatly among ...

journal_title：World journal of gastroenterology

authors： Meng XF,Pan YW,Wang ZB,Duan WD

更新日期：2018-06-28 00:00:00

abstract：:Deficiencies in vitamins or other factors (B6, B12, folic acid, betaine) and genetic disorders for the metabolism of the non-protein amino acid-homocysteine (Hcy) lead to hyperhomocysteinemia (HHcy). HHcy is an integral component of several disorders including cardiovascular disease, neurodegeneration, diabetes and al...

journal_title：World journal of gastroenterology

authors： Ji C,Kaplowitz N

更新日期：2004-06-15 00:00:00

abstract：AIM:To investigate the frequency of serum IgA-antiendomysial antibody positivity in patients with low bone mineral density and to assess the risk group for screening of celiac disease. METHODS:One hundred and thirty-five patients (14 male, 121 female) with idiopathic low bone mineral density were evaluated. The median...

journal_title：World journal of gastroenterology

authors： Karakan T,Ozyemisci-Taskiran O,Gunendi Z,Atalay F,Tuncer C

更新日期：2007-06-07 00:00:00

abstract：AIM:To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS:One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed...

journal_title：World journal of gastroenterology

authors： Kamath MG,Pai CG,Kamath A,Kurien A

更新日期：2017-03-28 00:00:00

abstract：AIM:To improve the technique of tissue microarray (tissue chip). METHODS:A new tissue microarraying method was invented with a common microscope installed with a special holing needle, a sampling needle, and a special box fixing paraffin blocks on the microscope slide carrier. With the movement of microscope tube and ...

journal_title：World journal of gastroenterology

authors： Dan HL,Zhang YL,Zhang Y,Wang YD,Lai ZS,Yang YJ,Cui HH,Jian YT,Geng J,Ding YQ,Guo CH,Zhou DY

更新日期：2004-02-15 00:00:00

abstract：AIM:To study the hemodynamics in the immediate post transplant period and compare patients with alcoholic vs viral cirrhosis. METHODS:Between 2000-2003, 38 patients were transplanted for alcoholic cirrhosis and 28 for postviral cirrhosis. Heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP), pu...

journal_title：World journal of gastroenterology

authors： Al-Hamoudi WK,Alqahtani S,Tandon P,Ma M,Lee SS

更新日期：2010-02-07 00:00:00

abstract：:Liver resection for hepatocellular carcinoma (HCC) is currently known to be a safer procedure than it was before because of technical advances and improvement in postoperative patient management and remains the first-line treatment for HCC in compensated cirrhosis. The aim of this review is to assess current indicatio...

journal_title：World journal of gastroenterology

authors： Gaillard M,Tranchart H,Dagher I

更新日期：2014-05-07 00:00:00

abstract：AIM:To examine fibrinogen-like protein 2 (fgl2) expression during taurocholate-induced acute pancreatitis progression in rats and its correlation with pancreatic injury severity. METHODS:Forty-eight male Sprague-Dawley rats were randomly divided into the severe acute pancreatitis (SAP) group (n = 24) and the sham oper...

journal_title：World journal of gastroenterology

authors： Ye XH,Chen TZ,Huai JP,Lu GR,Zhuge XJ,Chen RP,Chen WJ,Wang C,Huang ZM

更新日期：2013-04-28 00:00:00

abstract：:Patients with long-standing inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer (CRC). Many of the molecular alterations responsible for sporadic colorectal cancer, namely chromosomal instability, microsatellite instability, and hypermethylation, also play a role in colitis-associat...

journal_title：World journal of gastroenterology

authors： Xie J,Itzkowitz SH

更新日期：2008-01-21 00:00:00

abstract：:Gastroduodenal disease (GDD) was initially thought to be uncommon in Africa. Amongst others, lack of access to optimal health infrastructure and suspicion of conventional medicine resulted in the reported prevalence of GDD being significantly lower than that in other areas of the world. Following the increasing availa...

journal_title：World journal of gastroenterology

authors： Archampong TN,Asmah RH,Richards CJ,Martin VJ,Bayliss CD,Botão E,David L,Beleza S,Carrilho C

更新日期：2019-07-14 00:00:00

abstract：AIM:To determine the clinical effectiveness of intense psychological support to physical activity (PA) in nonalcoholic fatty liver disease (NAFLD), compared with cognitive-behavioral treatment (CBT). METHODS:Twenty-two NAFLD cases received support to exercise, tailored to their motivational needs (PA group). The effec...

journal_title：World journal of gastroenterology

authors： Montesi L,Caselli C,Centis E,Nuccitelli C,Moscatiello S,Suppini A,Marchesini G

更新日期：2014-08-07 00:00:00

abstract：AIM:To investigate the effect of hepatitis B virus (HBV) specific immunoglobin (HBIG) and lamivudine on HBV intrauterine transmission in HBsAg positive pregnant women. METHODS:Each subject in the HBIG group (56 cases) was given 200 IU HBIG intramuscularly (im.) every 4 weeks from 28-week (wk) of gestation, while each ...

journal_title：World journal of gastroenterology

authors： Li XM,Yang YB,Hou HY,Shi ZJ,Shen HM,Teng BQ,Li AM,Shi MF,Zou L

更新日期：2003-07-01 00:00:00

abstract：AIM:To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS:Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean ...

journal_title：World journal of gastroenterology

authors： Hwang J,Kim JS,Kim AY,Lim JS,Kim SH,Kim MJ,Kim MS,Song KD,Woo JY

更新日期：2017-07-07 00:00:00

abstract：AIM:Previous reports have shown that decrease in plasma glutamine (Gln) level following major surgery may contribute to the state of immunosuppression. Gln supplementation improves the depletion of body Gln pool, and may have indirect effect on reducing proinflammatory mediator release. This study evaluated whether the...

journal_title：World journal of gastroenterology

authors： Lin MT,Kung SP,Yeh SL,Liaw KY,Wang MY,Kuo ML,Lee PH,Chen WJ

更新日期：2005-10-21 00:00:00

abstract：:Laparoscopic gastrectomy has been widely accepted as a standard alternative for the treatment of early-stage gastric adenocarcinoma because of its favorable short-term outcomes. Although controversies exist, such as establishing clear indications, proper preoperative staging, and oncologic safety, experienced surgeons...

journal_title：World journal of gastroenterology

authors： Son T,Hyung WJ

更新日期：2016-01-14 00:00:00

abstract：AIM:To investigate the prognostic value of the expression of connexin (Cx) 26, 32 and 43 messenger RNA (mRNA) in hepatocellular carcinoma (HCC) tissues. METHODS:Using a reverse-transcriptase polymerase chain reaction (RT-PCR), Cx 26, Cx 32 and Cx 43 mRNAs were determined in the liver tissues of 15 controls and in HCC ...

journal_title：World journal of gastroenterology

authors： Sheen IS,Jeng KS,Wang PC,Shih SC,Chang WH,Wang HY,Chen CC,Shyung LR

更新日期：2004-10-01 00:00:00

abstract：AIM:Heat shock protein (HSP)70 is over-expressed in human gastric cancer and plays an important role in the progression of this cancer. We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer. METHODS:Human gastric cance...

journal_title：World journal of gastroenterology

authors： Zhao ZG,Shen WL

更新日期：2005-01-07 00:00:00

abstract：AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS:Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric ...

journal_title：World journal of gastroenterology

authors： Moleda L,Jurzik L,Froh M,Gäbele E,Hellerbrand C,Straub RH,Schölmerich J,Wiest R

更新日期：2010-04-21 00:00:00

abstract：:Hilar tumors have proven to be a challenge to treat and manage because of their poor sensitivity to conventional therapies and our inability to prevent or to detect early tumor formation. Endoscopic stent drainage has been proposed as an alternative to biliary-enteric bypass surgery and percutaneous drainage to pallia...

journal_title：World journal of gastroenterology

authors： De Palma GD,Masone S,Rega M,Simeoli I,Salvatori F,Siciliano S,Maione F,Girardi V,Celiento M,Persico G

更新日期：2007-08-14 00:00:00

abstract：AIM:To establish an animal model with human hepatocyte-repopulated liver for the study of liver cancer metastasis. METHODS:Cell transplantation into mouse livers was conducted using alpha-fetoprotein (AFP)-producing human gastric cancer cells (h-GCCs) and h-hepatocytes as donor cells in a transgenic mouse line express...

journal_title：World journal of gastroenterology

authors： Fujiwara S,Fujioka H,Tateno C,Taniguchi K,Ito M,Ohishi H,Utoh R,Ishibashi H,Kanematsu T,Yoshizato K

更新日期：2012-08-07 00:00:00

abstract：:Epidemiological and clinical data point to a close association between chronic hepatitis B virus infection or chronic hepatitis C virus infection and development of hepatocellular carcinoma (HCC). HCC develops over several decades and is associated with fibrosis. This sequence suggests that persistent viral infection ...

journal_title：World journal of gastroenterology

authors： Murata M,Yoshida K,Yamaguchi T,Matsuzaki K

更新日期：2014-11-07 00:00:00

abstract：AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specific to 16S rRNA of Helicobacter spp. was performed on paraffin-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The sample...

journal_title：World journal of gastroenterology

authors： Karagin PH,Stenram U,Wadström T,Ljungh A

更新日期：2010-10-14 00:00:00

abstract：AIM:To explore the effects of peptide S-8300 from shark liver (S-8300) on liver function as well as in regulating immune functions in experimental injury models. METHODS:Mice were administered with different doses of S-8300 for four consecutive days, followed by mice injected with tetrachloromethane (CCl(4)) on d 3. T...

journal_title：World journal of gastroenterology

authors： Huang FJ,Lv ZB,Li Q,Wei LJ,Zhang L,Wu WT

更新日期：2005-03-28 00:00:00