Prediction of the indication criteria for endoscopic resection of early gastric cancer.

Abstract:

AIM:To find risk factors of lymph node metastasis (LNM) in early gastric cancer (EGC) and to find proper endoscopic therapy indication in EGC. METHODS:We retrospectively reviewed the 2270 patients who underwent curative operation for EGC from January 2001 to December 2008. EGC was defined as malignant lesions that do not invade beyond the submucosal layer of the stomach wall irrespective of presence of lymph node metastasis. RESULTS:Among 2270 enrolled patients, LNM was observed in 217 (9%) patients. LNM in intramucosal (M) cancer and submucosal (SM) cancer was detected in 38 (2.8%, 38/1340) patients and 179 (19%, 179/930) patients, respectively. In univariate analysis, the risk factors for LNM in EGC were size of tumor, Lauren classification, ulcer, lymphatic invasion, vascular invasion, and depth of invasion. However, in multivariate analysis, size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in EGC. Size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in cases of intramucosal cancer and submucosal cancer. In particular, there was no lymph node metastasis in cases of well differentiated early gastric cancer below 1 cm in size without ulcer regardless of lymphovascular invasion. CONCLUSION:Tumor size, perilymphatic-vascular invasion, and depth of invasion were risk factors for LNM in EGC. There was no LNM in EGC below 1 cm regardless risk factors.

journal_name

World J Gastroenterol

authors

Park JH,Lee SH,Park JM,Park CS,Park KS,Kim ES,Cho KB

doi

10.3748/wjg.v21.i39.11160

subject

Has Abstract

pub_date

2015-10-21 00:00:00

pages

11160-7

issue

39

eissn

1007-9327

issn

2219-2840

journal_volume

21

pub_type

杂志文章
  • Anemia and long-term outcome in adjuvant and neoadjuvant radiochemotherapy of stage II and III rectal adenocarcinoma: the Freiburg experience (1989-2002).

    abstract:AIM:To evaluate the long-term outcome of standard 5-FU based adjuvant or neoadjuvant radiochemotherapy and to identify the predictive factors, especially anemia before and after radiotherapy as well as hemoglobin increase or decrease during radiotherapy. METHODS:Two hundred and eighty-six patients with Union Internati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i12.1849

    authors: Weissenberger C,Geissler M,Otto F,Barke A,Henne K,von Plehn G,Rein A,Muller C,Bartelt S,Henke M

    更新日期:2006-03-28 00:00:00

  • Hepatobiliary and pancreatic disorders in celiac disease.

    abstract::A variety of hepatic and biliary tract disorders may complicate the clinical course of celiac disease. Some of these have been hypothesized to share common genetic factors or have a common immunopathogenesis, such as primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune forms of hepatitis or cholang...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v12.i10.1503

    authors: Freeman HJ

    更新日期:2006-03-14 00:00:00

  • Telomeres, telomerase and colorectal cancer.

    abstract::Colorectal cancer (CRC) is the third most common cancer worldwide and, despite improved treatments, is still an important cause of cancer-related deaths. CRC encompasses a complex of diseases arising from a multi-step process of genetic and epigenetic events. Besides heterogeneity in the molecular and biological featu...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i8.1940

    authors: Bertorelle R,Rampazzo E,Pucciarelli S,Nitti D,De Rossi A

    更新日期:2014-02-28 00:00:00

  • Enhanced expression of epidermal growth factor receptor gene in gastric mucosal cells by the serum derived from rats treated with electroacupuncture at stomach meridian acupoints.

    abstract:AIM:To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS:The stress-induced gastric mucosal injury in rat model was established by water-immersion and restra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i34.5557

    authors: Yang ZB,Yan J,Zou XP,Yi SX,Chang XR,Lin YP,Li XP

    更新日期:2006-09-14 00:00:00

  • Possible causes of central pontine myelinolysis after liver transplantation.

    abstract:AIM:To sum up the clinical characteristics of patients with central pontine myelinolysis (CPM) after orthotopic liver transplantation (OLT) and to document the possible causes of CPM. METHODS:Data of 142 patients undergoing OLT between January 1999 to May 2003 were analyzed retrospectively. Following risk factors duri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i17.2540

    authors: Yu J,Zheng SS,Liang TB,Shen Y,Wang WL,Ke QH

    更新日期:2004-09-01 00:00:00

  • Synergetic anticancer effect of combined gemcitabine and photodynamic therapy on pancreatic cancer in vivo.

    abstract:AIM:To investigate the anti-tumor effects of combined cytotoxic drug (gemcitabine) and photodynamic therapy (PDT) on human pancreatic cancer xenograft in nude mice. METHODS:Human pancreatic cancer cell line SW1990 was used in the investigation of the in vivo effect of combined gemcitabine and PDT on human pancreatic c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.737

    authors: Xie Q,Jia L,Liu YH,Wei CG

    更新日期:2009-02-14 00:00:00

  • Replication and gene expression of mutant hepatitis B virus in a transgenic mouse containing the complete viral genome with mutant s gene.

    abstract:AIM:To establish the transgenic mouse line harbouring complete hepatitis B virus (HBV) genome with mutant s gene (adr subtype). METHODS:Transgenic mice were generated by microinjecting HBV genome into fertilized eggs. Integration, expression, replication of HBV gene and histological changes in transgenic mice were est...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i21.3141

    authors: Ge JH,Zhang LZ,Li JX,Liu H,Liu HM,He J,Yao YC,Yang YJ,Yu HY,Hu YP

    更新日期:2004-11-01 00:00:00

  • Incidence and mortality of primary liver cancer in England and Wales: changing patterns and ethnic variations.

    abstract:AIM:To explore recent trends, modes of diagnosis, ethnic distribution and the mortality to incidence ratio of primary liver cancer by subtypes in England and Wales. METHODS:We obtained incidence (1979-2008) and mortality (1968-2008) data for primary liver cancer for England and Wales and calculated age-standardised in...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i6.1544

    authors: Ladep NG,Khan SA,Crossey MM,Thillainayagam AV,Taylor-Robinson SD,Toledano MB

    更新日期:2014-02-14 00:00:00

  • Basaloid squamous carcinoma of esophagus:a clinicopathological, immunohistochemical and electron microscopic study of sixteen cases.

    abstract::AIM:To further clarify the clinicopathological, immunohistochemical and electron microscopic features, and prognostic aspect of basaloid squamous carcinoma (BSC), a rare esophageal carcinoma.METHODS:We reviewed 763 documented cases of esophageal malignancies from year (1977-1996) from our hospital, and discovered 16 (...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v4.i5.397

    authors: Zhang XH,Sun GQ,Zhou XJ,Guo HF,Zhang TH

    更新日期:1998-10-01 00:00:00

  • Anisodamine accelerates spontaneous passage of single symptomatic bile duct stones ≤ 10 mm.

    abstract:AIM:To investigate the rate of spontaneous passage of single and symptomatic common bile duct (CBD) stones ≤ 10 mm in diameter in 4 wk with or without a 2-wk course of anisodamine. METHODS:A multicenter, randomized, placebo-controlled trial was undertaken. A total of 197 patients who met the inclusion criteria were en...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3748/wjg.v19.i39.6618

    authors: Gao J,Ding XM,Ke S,Zhou YM,Qian XJ,Ma RL,Ning CM,Xin ZH,Sun WB

    更新日期:2013-10-21 00:00:00

  • Interleukin-28 and hepatitis C virus genotype-4: treatment-induced clearance and liver fibrosis.

    abstract:AIM:To investigate the association between interleukin-28B (IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus (HCV) genotype 4. METHODS:Two hundred and one HCV-genotype 4 patients were included. All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk. End...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i47.7003

    authors: Derbala M,Rizk N,Shebl F,Alkaabi S,Eldweik N,John A,Sharma M,Yaqoob R,Almohanadi M,Butt M,Alejji K

    更新日期:2012-12-21 00:00:00

  • Hepatitis B virus preS1 deletion is related to viral replication increase and disease progression.

    abstract:AIM:To investigate the clinical implications of hepatitis B virus (HBV) preS1 deletion. METHODS:We developed a fluorescence resonance energy transfer-based real-time polymerase chain reaction (RT-PCR) that can detect four genotypes (wild type, 15-bp, 18-bp and 21-bp deletion). The PCR method was used in two cohorts of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v21.i16.5039

    authors: Lee SA,Kim KJ,Kim H,Choi WH,Won YS,Kim BJ

    更新日期:2015-04-28 00:00:00

  • Upper gastrointestinal bleeding in Scotland 2000-2010: Improved outcomes but a significant weekend effect.

    abstract:AIM:To assess numbers and case fatality of patients with upper gastrointestinal bleeding (UGIB), effects of deprivation and whether weekend presentation affected outcomes. METHODS:Data was obtained from Information Services Division (ISD) Scotland and National Records of Scotland (NRS) death records for a ten year per...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i38.10890

    authors: Ahmed A,Armstrong M,Robertson I,Morris AJ,Blatchford O,Stanley AJ

    更新日期:2015-10-14 00:00:00

  • One case of intrahepatic cholangiocarcinoma amenable to resection after radioembolization.

    abstract::We report the case of a 57-year-old man who was diagnosed with a large unresectable cholangiocarcinoma associated with 2 satellite nodules and without clear margins with the right hepatic vein. Despite 4 cycles of GEMOX (stopped due to a hypertransaminasemia believed to be due to gemcitabine) and 4 cycles of FOLFIRINO...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i17.5131

    authors: Servajean C,Gilabert M,Piana G,Monges G,Delpero JR,Brenot I,Raoul JL

    更新日期:2014-05-07 00:00:00

  • Transjugular intrahepatic portosystemic shunt for pyrrolizidine alkaloid-related hepatic sinusoidal obstruction syndrome.

    abstract:BACKGROUND:Treatments for hepatic sinusoidal obstruction syndrome (HSOS) are limited. AIM:To evaluate transjugular intrahepatic portosystemic shunting (TIPS) as a treatment for pyrrolidine alkaloid-related HSOS (PA-HSOS). METHODS:This retrospective analysis included patients with PA-HSOS admitted to the First Affilia...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i24.3472

    authors: Zhou CZ,Wang RF,Lv WF,Fu YQ,Cheng DL,Zhu YJ,Hou CL,Ye XJ

    更新日期:2020-06-28 00:00:00

  • Single daily amikacin versus cefotaxime in the short-course treatment of spontaneous bacterial peritonitis in cirrhotics.

    abstract:AIM:To compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (SBP). METHODS:Thirty-seven cirrhotic patients with SBP, 19 in group A and 18 in group B, were studied. Group A received 1 g of cefotaxime every 6 h, and group B received 500 mg of a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v11.i43.6823

    authors: Chen TA,Lo GH,Lai KH,Lin WJ

    更新日期:2005-11-21 00:00:00

  • Therapeutic advances: single incision laparoscopic hepatopancreatobiliary surgery.

    abstract::Single-port laparoscopic surgery (SPLS) is proposed to be a step towards minimizing the invasiveness of surgery, and has since gained popularity in several surgical sub-specialties including hepatopancreatobiliary surgery. SPLS has since been applied to cholecystectomy, liver resection as well as pancreatectomy for a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i39.14329

    authors: Chang SK,Lee KY

    更新日期:2014-10-21 00:00:00

  • Mesenteric inflammatory myofibroblastic tumors in an elder patient with early recurrence: a case report.

    abstract::Inflammatory myofibroblastic tumor (IMT) of the alimentary tract often occurs in children or young adults, but may occur at any age. Symptoms are nonspecific and depend on the location of the tumor. The most often involved sites are small bowel mesentery especially the distal ileum, mesotransverse colon, or great omen...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i26.3645

    authors: Chen SS,Liu SI,Mok KT,Wang BW,Yeh MH,Chen YC,Chen IS

    更新日期:2007-07-14 00:00:00

  • Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?

    abstract::Hepatitis B virus (HBV) is the leading cause of liver disease and infects an estimated 240 million people worldwide. It is characterised by a high degree of genetic heterogeneity because of the use of a reverse transcriptase during viral replication. The ten genotypes (A-J) that have been described so far further segr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i24.7622

    authors: Zehender G,Ebranati E,Gabanelli E,Sorrentino C,Lo Presti A,Tanzi E,Ciccozzi M,Galli M

    更新日期:2014-06-28 00:00:00

  • miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate.

    abstract:AIM:To explore the role and potential mechanism of miR-30b regulation of autophagy in hepatic ischemia-reperfusion injury (IRI). METHODS:An animal model of hepatic IRI was generated in C57BL/6 mice. For in vitro studies, AML12 cells were immersed in mineral oil for 1 h and then cultured in complete Dulbecco's Modified...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i18.4501

    authors: Li SP,He JD,Wang Z,Yu Y,Fu SY,Zhang HM,Zhang JJ,Shen ZY

    更新日期:2016-05-14 00:00:00

  • Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer.

    abstract:AIM:Overexpression of tumor protein p53-induced nuclear protein 1 (TP53INP1) induces G1 cell cycle arrest and increases p53-mediated apoptosis. To clarify the clinical importance of TP53INP1, we analyzed TP53INP1 and p53 expression in gastric cancer. METHODS:TP53INP1 and p53 expression were examined using immunohistoc...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i5.691

    authors: Jiang PH,Motoo Y,Garcia S,Iovanna JL,Pébusque MJ,Sawabu N

    更新日期:2006-02-07 00:00:00

  • Seek protein which can interact with hepatitis B virus X protein from human liver cDNA library by yeast two-hybrid system.

    abstract:AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i1.95

    authors: Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

    更新日期:2002-02-01 00:00:00

  • Efficiency and safety of radiofrequency-assisted hepatectomy for hepatocellular carcinoma with cirrhosis: A single-center retrospective cohort study.

    abstract:AIM:To assess the efficiency and safety of radiofrequency-assisted hepatectomy in patients with hepatocellular carcinoma (HCC) and cirrhosis. METHODS:From January 2010 to December 2013, 179 patients with HCC and cirrhosis were recruited for this retrospective study. Of these, 100 patients who received radiofrequency-a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i35.10159

    authors: Zhang F,Yan J,Feng XB,Xia F,Li XW,Ma KS,Bie P

    更新日期:2015-09-21 00:00:00

  • Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.

    abstract:AIM:To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats. METHODS:Gastric injury was assessed by measuring ulcerated legions 4 h after indomethacin (25 mg/kg) administration. Small intestinal injury was assessed by measuring ulcerated legions 24 h after indomet...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i10.2641

    authors: Yamamoto A,Itoh T,Nasu R,Nishida R

    更新日期:2014-03-14 00:00:00

  • Mycobacterium avium subspecies paratuberculosis in the etiology of Crohn's disease, cause or epiphenomenon?

    abstract::The origin of inflammatory bowel disease is unknown. Attempts have been made to isolate a microorganism that could explain the onset of inflammation, but no pathological agent has ever been identified. Johne's disease is a granulomatous chronic enteritis of cattle and sheep caused by Mycobacterium avium subspecies par...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i36.13060

    authors: Liverani E,Scaioli E,Cardamone C,Dal Monte P,Belluzzi A

    更新日期:2014-09-28 00:00:00

  • Ampulla dilation with different sized balloons to remove common bile duct stones.

    abstract:AIM:To assess the outcomes of ampulla dilation with different sized balloons to remove common bile duct (CBD) stones. METHODS:Patients (n = 208) were divided into five groups based on the largest CBD stone size of < 5, 6-8, 8-12, 12-14, and > 14 mm. Patients underwent limited endoscopic sphincterotomy (EST) alone or l...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i6.903

    authors: Li NP,Liu JQ,Zhou ZQ,Ji TY,Cai XY,Zhu QY

    更新日期:2013-02-14 00:00:00

  • Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide.

    abstract:AIM:To study the effect of nicotine on the migration and invasion of human esophageal squamous carcinoma cells and to investigate whether nimesulide can inhibit the effect of nicotine. METHODS:The esophageal squamous carcinoma cell line (TE-13) was treated with different concentrations of nicotine (100 microg/mL and 2...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.2500

    authors: Zong Y,Zhang ST,Zhu ST

    更新日期:2009-05-28 00:00:00

  • Paraneoplastic hyperinsulinism and secondary hypoglycaemia in a patient with advanced colon cancer: a rare association.

    abstract::We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.1952

    authors: Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

    更新日期:2008-03-28 00:00:00

  • Rare long-term survivors of pancreatic adenocarcinoma without curative resection.

    abstract::Long-term outcome data in pancreatic adenocarcinoma are predominantly based on surgical series, as resection is currently considered essential for long-term survival. In contrast, five-year survival in non-resected patients has rarely been reported. In this report, we examined the incidence and natural history of ≥ 5-...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i48.13574

    authors: Oh SY,Edwards A,Mandelson MT,Lin B,Dorer R,Helton WS,Kozarek RA,Picozzi VJ

    更新日期:2015-12-28 00:00:00

  • Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma.

    abstract:AIM:To investigate the relationship between c.343A>G and c.2216A>C polymorphism sites in the CDH17 gene and colorectal carcinoma. METHODS:Ninety-three non-consanguineous colorectal carcinoma patients admitted to the Department of Oncology at the First Affiliated Hospital of Zhengzhou University were included in this s...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i48.7251

    authors: Chen RY,Cao JJ,Chen J,Yang JP,Liu XB,Zhao GQ,Zhang YF

    更新日期:2012-12-28 00:00:00