Recent trends in the treatment of well-differentiated endocrine carcinoma of the small bowel.

abstract：:Gastric cancer is one of the most common malignant tumors worldwide. Due to its intricate initiation and progression mechanisms, early detection and effective treatment of gastric cancer are difficult to achieve. The epithelial-mesenchymal transition (EMT) is characterized as a fundamental process that is critical for...

journal_title：World journal of gastroenterology

authors： Peng Z,Wang CX,Fang EH,Wang GB,Tong Q

更新日期：2014-05-14 00:00:00

abstract：:Novel molecular targets are being discovered as we learn more about the aberrant processes underlying various cancers. Efforts to translate this knowledge are starting to impact on the care of patients with gastrointestinal cancers. The epidermal growth factor receptor (EGFR) pathway and angiogenesis have been targete...

journal_title：World journal of gastroenterology

authors： Ma WW,Hidalgo M

更新日期：2007-11-28 00:00:00

abstract：AIM:To determine the precise incidence and clinical features of endoscopic ulcers following gastrectomy. METHODS:A consecutive series of patients who underwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ...

journal_title：World journal of gastroenterology

authors： Chung WC,Jeon EJ,Lee KM,Paik CN,Jung SH,Oh JH,Kim JH,Jun KH,Chin HM

更新日期：2012-07-07 00:00:00

abstract：AIM:To explore the effects of the nucleoside analogues beta-L-D4A and beta-LPA on hepatitis B virus (HBV) promoters. METHODS:Four HBV promoters were amplified by polymerase chain reaction (PCR) and subcloned into the expression vector pEGFP-1. The four recombinants controlled by HBV promoters were confirmed by restric...

journal_title：World journal of gastroenterology

authors： He XX,Lin JS,Chang Y,Zhang YH,Li Y,Wang XY,Xu D,Cheng XM

更新日期：2008-03-28 00:00:00

abstract：AIM:To examine the association between parity and gastric cancer (the cases are almost all premenopausal women) risk in a cohort of young parous women. METHODS:The study cohort consisted of all women with a record of a first and singleton childbirth in the Birth Register between 1978 and 1987. We tracked each woman fr...

journal_title：World journal of gastroenterology

authors： Chang CC,Chen CC,Chiu HF,Yang CY

更新日期：2011-02-14 00:00:00

abstract：AIM:To investigate whether hypoxia inducible factor-1alpha (HIF-1alpha) is linked to the protective effects of ischemic preconditioning (IP) on sinusoidal endothelial cells against ischemia/reperfusion injury. METHODS:Sinusoidal endothelial cell lines ECV-304 were cultured and divided into four groups: control group, ...

journal_title：World journal of gastroenterology

authors： Shi LB,Huang JH,Han BS

更新日期：2007-04-28 00:00:00

abstract：:Sorafenib, a potent multikinase inhibitor, lead to a significant improvement in progression free survival and overall survival in patients with advanced hepatocellular carcinoma (HCC). Though sorafenib has proven its efficacy in advanced stage HCC, there are limited reports on the role of sorafenib allowing for curati...

journal_title：World journal of gastroenterology

authors： Park JG,Park SY,Lee HW

更新日期：2015-02-28 00:00:00

abstract：:The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently been approved for this disease, response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment ...

journal_title：World journal of gastroenterology

authors： Wich C,Agaimy A,Strobel D,Wissniowski TT,Hartmann A,Ocker M

更新日期：2010-07-28 00:00:00

abstract：:External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated with a higher recurrence rate, an abdominal approach is commonly preferred. Despit...

journal_title：World journal of gastroenterology

authors： van Iersel JJ,Paulides TJ,Verheijen PM,Lumley JW,Broeders IA,Consten EC

更新日期：2016-06-07 00:00:00

abstract：:Portal hypertension can be caused by a wide variety of conditions. It frequently presents with bleeding from esophageal varices. The approach to acute variceal hemorrhage in children is a stepwise progression from least invasive to most invasive. Management of acute variceal bleeding is straightforward. But data on pr...

journal_title：World journal of gastroenterology

authors： Gugig R,Rosenthal P

更新日期：2012-03-21 00:00:00

abstract：AIM:To evaluate the efficacy of 5 compared to 10 granulocyteaphaeresis sessions in patients with active steroid-dependent ulcerative colitis. METHODS:In this pilot, prospective, multicenter randomized trial, 20 patients with moderately active steroid-dependent ulcerative colitis were randomized to 5 or 10 granulocytea...

journal_title：World journal of gastroenterology

authors： Ricart E,Esteve M,Andreu M,Casellas F,Monfort D,Sans M,Oudovenko N,Lafuente R,Panes J

更新日期：2007-04-21 00:00:00

abstract：AIM:To investigate the efficacy and side effects of the combined therapy of oxaliplatin and capecitabine in patients with metastatic esophageal squamous cell cancer (ESCC) and the survival of the patients. METHODS:Sixty-four patients (median age of 63 years) with histological or cytological confirmation of ESCC receiv...

journal_title：World journal of gastroenterology

authors： Qin TJ,An GL,Zhao XH,Tian F,Li XH,Lian JW,Pan BR,Gu SZ

更新日期：2009-02-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide. Multiple treatment options are available for HCC including curative resection, liver transplantation, radiofrequency ablation, trans-arterial chemoembolization, radioembolization and systemic targeted agent like sorafenib. The treatment of HCC de...

journal_title：World journal of gastroenterology

authors： Raza A,Sood GK

更新日期：2014-04-21 00:00:00

abstract：:As among persons with normal anatomy, occasional patients with situs inversus develop malignant tumors. Recently, several laparoscopic operations have been reported in patients with situs inversus. We describe laparoscopic hemicolectomy with radical lymphadenectomy in such a patient. Careful consideration of the mirro...

journal_title：World journal of gastroenterology

authors： Fujiwara Y,Fukunaga Y,Higashino M,Tanimura S,Takemura M,Tanaka Y,Osugi H

更新日期：2007-10-07 00:00:00

abstract：AIM:To investigate the efficacy and safety of gemcitabine (Gem)-based combination chemotherapies for the treatment of advanced biliary tract cancer. METHODS:Clinical trials were identified by searching scientific literature databases (PubMed, EMBASE and the Cochrane Library) for studies published between 1975 and 2013...

journal_title：World journal of gastroenterology

authors： Liu H,Zhang QD,Li ZH,Zhang QQ,Lu LG

更新日期：2014-12-21 00:00:00

abstract：AIM:To investigate whether continuous veno-venous hemofiltration (CVVH) in different filtration rate to eliminate cytokines would result in different efficiency in acute pancreatitis, whether the saturation time of filter membrane was related to different filtration rate, and whether the onset time of CVVH could influe...

journal_title：World journal of gastroenterology

authors： Jiang HL,Xue WJ,Li DQ,Yin AP,Xin X,Li CM,Gao JL

更新日期：2005-08-21 00:00:00

abstract：AIM:To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC). METHODS:The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its p...

journal_title：World journal of gastroenterology

authors： Sun XD,Cai XY,Li JD,Cai XJ,Mu YP,Wu JM

更新日期：2003-04-01 00:00:00

abstract：AIM:To investigate the effect of integrin-linked kinase (ILK) on proliferation, metastasis, and invasion of the colorectal cancer cell line SW480. METHODS:In this study, the colorectal cancer cell line SW480 was stably transfected with ILK plasmids, and small interfering RNA (siRNA) was used to knockdown expression of...

journal_title：World journal of gastroenterology

authors： Shen H,Ma JL,Zhang Y,Deng GL,Qu YL,Wu XL,He JX,Zhang S,Zeng S

更新日期：2016-04-21 00:00:00

abstract：:Gastrin is the main hormone responsible for the stimulation of gastric acid secretion; in addition, gastrin and its derivatives exert proliferative and antiapoptotic effects on several cell types. Gastrin synthesis and secretion are increased in certain situations, for example, when proton pump inhibitors are used. Th...

journal_title：World journal of gastroenterology

authors： Chueca E,Lanas A,Piazuelo E

更新日期：2012-12-07 00:00:00

abstract：BACKGROUND:Incidence and severity variations of inflammatory bowel disease (IBD) have been reported from Western populations between continents and regions of the same countries. However, no data were available from other countries. AIM:To investigate the regional differences in the IBD profiles of pediatric patients ...

journal_title：World journal of gastroenterology

authors： El Mouzan MI,AlEdreesi MH,Hasosah MY,Al-Hussaini AA,Al Sarkhy AA,Assiri AA

更新日期：2020-01-28 00:00:00

abstract：AIM:To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibility to hepatitis B virus (HBV) infection and progression of liver diseases among clinically classified Vietnamese patients. METHODS:Four IFR5 SNPs (rs13242262A/T, rs77416878C/T, rs10488630A/G, and rs2280714T/...

journal_title：World journal of gastroenterology

authors： Sy BT,Hoan NX,Tong HV,Meyer CG,Toan NL,Song LH,Bock CT,Velavan TP

更新日期：2018-01-14 00:00:00

abstract：AIM:To investigate the ultrastructure of abnormal hepatocyte mitochondria, including their cellular and hepatic zonal distribution, in bioptates in pediatric non-alcoholic steatohepatitis (NASH). METHODS:Ultrastructural investigations were conducted on biopsy liver specimens obtained from 10 children (6 boys and 4 gir...

journal_title：World journal of gastroenterology

authors： Lotowska JM,Sobaniec-Lotowska ME,Bockowska SB,Lebensztejn DM

更新日期：2014-04-21 00:00:00

abstract：AIM:To explore the grade and stage of pathology and the relationship between grading and staging of hepatic fibrosis and noninvasive diagnostic parameters. METHODS:Inflammatory activity and fibrosis of consecutive liver biopsies from 200 patients with chronic liver disease were determined according to the Diagnostic C...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Wan MB,Li CZ,Mao YM,Li JQ,Qiu DK,Cao AP,Ye J,Cai X,Chen CW,Wang JY,Wu SM,Zhu JS,Zhou XQ

更新日期：2003-11-01 00:00:00

abstract：AIM:To assess the effectiveness of endoscopic full-thickness resection (EFR) and laparoscopic surgery in the treatment of gastric stromal tumors arising from the muscularis propria. METHODS:Out of 62 gastric stromal tumors arising from the muscularis propria, each > 1.5 cm in diameter, 32 were removed by EFR, and 30 w...

journal_title：World journal of gastroenterology

authors： Huang LY,Cui J,Wu CR,Zhang B,Jiang LX,Xian XS,Lin SJ,Xu N,Cao XL,Wang ZH

更新日期：2014-07-07 00:00:00

abstract：AIM:To investigate the anticancer effect of a recombinant adenovirus-mediated p53 (rAd-p53) combined with 5-fluorouracil (5-FU) in human colon cancer resistant to 5-FU in vivo and the mechanism of rAd-p53 in reversal of 5-FU resistance. METHODS:Nude mice bearing human colon cancer SW480/5-FU (5-FU resistant) were rand...

journal_title：World journal of gastroenterology

authors： Xie Q,Wu MY,Zhang DX,Yang YM,Wang BS,Zhang J,Xu J,Zhong WD,Hu JN

更新日期：2016-08-28 00:00:00

abstract：AIM:To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery. METHODS:The medical records of patients who underwent endoscopic self-expanding metal stents (SEMS) insertion for colorectal obstructions between February 2004 and Janua...

journal_title：World journal of gastroenterology

authors： Kim JH,Lee JJ,Cho JH,Kim KO,Chung JW,Kim YJ,Kwon KA,Park DK,Kim JH

更新日期：2014-10-14 00:00:00

abstract：AIM:To evaluate the functional aspect of esophageal motility in healthy subjects and in patients who were referred for esophageal function testing using multichannel intraluminal impedance-esophageal manometry (MII-EM), and to assess the clinical utility of MII-EM. METHODS:From September 2003 to January 2004, we perfo...

journal_title：World journal of gastroenterology

authors： Cho YK,Choi MG,Park JM,Oh JH,Paik CN,Lee JW,Lee IS,Kim SW,Chung IS

更新日期：2006-10-21 00:00:00

abstract：:We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum. Endoscopic mucosal resection (EMR) was carried out successfully and completely with the assistance of laparoscopy. A 71-year-old man was admitted to our hospital because of melena and anemia. Emergent colon...

journal_title：World journal of gastroenterology

authors： Fu KI,Hamahata Y,Tsujinaka Y

更新日期：2010-03-28 00:00:00

abstract：:Cancer patients have unique problems associated with hepatitis C virus (HCV) infection and treatment not seen in the general population. HCV infection poses additional challenges and considerations for the management of cancer, and vice versa. HCV infection also can lead to the development of cancer, particularly hepa...

journal_title：World journal of gastroenterology

authors： Borchardt RA,Torres HA

更新日期：2014-03-21 00:00:00

abstract：AIM:To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past. METHODS:The causes and clinical outcome were compared between 105 patients with AUGB and a history of ga...

journal_title：World journal of gastroenterology

authors： Nikolopoulou VN,Thomopoulos KC,Theocharis GI,Arvaniti VA,Vagianos CE

更新日期：2005-08-07 00:00:00