Accumulation of aberrant DNA methylation during colorectal cancer development.

abstract：AIM:To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ¹³C-octanoic acid breath test in a mouse model. METHODS:Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g ¹³C-octanoic ...

journal_title：World journal of gastroenterology

authors： Lim CH,Choi MG,Park H,Baeg MK,Park JM

更新日期：2013-07-21 00:00:00

abstract：AIM:To describe a new clinical and pathological subtype of microscopic colitis in children. METHODS:A selected group of children with abdominal pain, constipation and/or diarrhoea showing discrete or no macroscopic abnormalities on endoscopy was described. RESULTS:Multiple biopsies of colon showed large mononuclear c...

journal_title：World journal of gastroenterology

authors： Józefczuk J,Wozniewicz BM

更新日期：2008-01-14 00:00:00

abstract：AIM:To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS:Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-naïve HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups...

journal_title：World journal of gastroenterology

authors： Akiyama T,Mizuta T,Kawazoe S,Eguchi Y,Kawaguchi Y,Takahashi H,Ozaki I,Fujimoto K

更新日期：2011-02-21 00:00:00

abstract：AIM:To define the common deleted region on the long arm of haman chromosome 7q linked to primary gastric carcinomas in Chinese by loss of heterozygosity (LOH) and its clinical significance. METHODS:Nine microsatellite markers distributed over chromosome 7q with an average marker density of 10cM were used to examine 70...

journal_title：World journal of gastroenterology

authors： Weng DS,Li JT,Mai SJ,Pan ZZ,Feng BJ,Feng QS,Huang LX,Wang QJ,Li YQ,Yu XJ,Chen SP,He J,Xia JC

更新日期：2006-04-21 00:00:00

abstract：:Casais et al have reported an inverse correlation between serum phosphate and body weight after administration of sodium phosphate at a dose of 60 g. Our group has already described the relationship between body weight and hyperphosphatemia with these preparations, although our study was not quoted by Casais. We perfo...

journal_title：World journal of gastroenterology

authors： Deepak P,Ehrenpreis ED

更新日期：2011-06-07 00:00:00

abstract：:Foreign body ingestion is a common complaint in gastrointestinal clinics. It is usually not difficult to diagnose because most of the patients report a definitive history of accidental foreign body ingestion. However, in rare cases, patients do not have a clear history. Thus, the actual condition of the patient is dif...

journal_title：World journal of gastroenterology

authors： Lu YP,Yao M,Zhou XY,Huang B,Qi WB,Chen ZH,Xu LS

更新日期：2014-10-21 00:00:00

abstract：:Recently, there have been reports from liver biopsies that showed the progression of liver fibrosis in liver transplant patients after the cessation of immunosuppression. Herein, we focused on activated hepatic stellate cells expressing alpha smooth muscle actin (α-SMA) to understand the correlation between immunosupp...

journal_title：World journal of gastroenterology

authors： Hirabaru M,Mochizuki K,Takatsuki M,Soyama A,Kosaka T,Kuroki T,Shimokawa I,Eguchi S

更新日期：2014-06-14 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：AIM:To investigate H(+), K(+)-ATPase inhibition, anti-H pylori, antioxidant, and the in vivo antiulcer potential of a pectic polysaccharide from Swallow root (Decalepis hamiltonii; SRPP). METHODS:SRPP, with known sugar composition [rhamnose: arabinose: xylose: galactose in the ratio of 16:50:2:32 (w/w), with 141 mg/g ...

journal_title：World journal of gastroenterology

authors： Srikanta B,Siddaraju M,Dharmesh S

更新日期：2007-10-21 00:00:00

abstract：AIM:To evaluate liver stiffness measurement (LSM) using non-invasive transient elastography (Fibroscan) in comparison with liver biopsy for assessment of liver fibrosis in children with biliary atresia (BA). METHODS:Thirty-one children with BA admitted to the Department of Pediatric Surgery of Beijing Children's Hospi...

journal_title：World journal of gastroenterology

authors： Shen QL,Chen YJ,Wang ZM,Zhang TC,Pang WB,Shu J,Peng CH

更新日期：2015-06-14 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

journal_title：World journal of gastroenterology

authors： Lazaraki G,Chatzimavroudis G,Katsinelos P

更新日期：2014-07-21 00:00:00

abstract：:Alverine citrate is a commonly used smooth muscle relaxant agent. A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent. A 34-year-old woman was investigated because of the finding of elevated liver function tests on biochemical screening. Other etiologies of hepatitis we...

journal_title：World journal of gastroenterology

authors： Arhan M,Koklu S,Koksal AS,Yolcu OF,Koruk S,Koruk I,Kayacetin E

更新日期：2004-08-01 00:00:00

abstract：AIM:To identify the scFv antibody fragments specific for hepatocellular carcinoma by biopanning from a large human naive scFv phage display library. METHODS:A large human naive scFv phage library was used to search for the specific targets by biopanning with the hepatocellular carcinoma cell line HepG2 for the positiv...

journal_title：World journal of gastroenterology

authors： Yu B,Ni M,Li WH,Lei P,Xing W,Xiao DW,Huang Y,Tang ZJ,Zhu HF,Shen GX

更新日期：2005-07-14 00:00:00

abstract：:Idiopathic achalasia is a rare primary motility disorder of the esophagus. The classical features are incomplete relaxation of a frequently hypertensive lower esophageal sphincter (LES) and a lack of peristalsis in the tubular esophagus. These motor abnormalities lead to dysphagia, stasis, regurgitation, weight loss, ...

journal_title：World journal of gastroenterology

authors： Eckardt AJ,Eckardt VF

更新日期：2009-08-28 00:00:00

abstract：:It has since long been known, from everyday experience as well as from animal and human studies, that psychological processes-both affective and cognitive-exert an influence on gastrointestinal sensorimotor function. More specifically, a link between psychological factors and visceral hypersensitivity has been suggest...

journal_title：World journal of gastroenterology

authors： Van Oudenhove L,Coen SJ,Aziz Q

更新日期：2007-07-07 00:00:00

abstract：AIM:To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS:p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by p21 promoter, and the...

journal_title：World journal of gastroenterology

authors： Gong GZ,Jiang YF,He Y,Lai LY,Zhu YH,Su XS

更新日期：2004-08-01 00:00:00

abstract：AIM:Small intestinal bacterial overgrowth (SIBO) may contribute to the appearance of several gastrointestinal nonspecific symptoms. Acute diverticulitis is affected by some similar symptoms and bacterial colonic overgrowth. We assessed the prevalence of SIBO in acute uncomplicated diverticulitis and evaluated its influ...

journal_title：World journal of gastroenterology

authors： Tursi A,Brandimarte G,Giorgetti GM,Elisei W

更新日期：2005-05-14 00:00:00

abstract：:Although gastric cancer (GC) is one of the leading causes of cancer-related death, major therapeutic advances have not been made, and patients with GC still face poor outcomes. The prognosis of GC also remains poor because the molecular mechanisms of GC progression are incompletely understood. MicroRNAs (miRNAs) are n...

journal_title：World journal of gastroenterology

authors： Ishiguro H,Kimura M,Takeyama H

更新日期：2014-05-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly invasive tumor that metastasizes hematogenously and lymphogenously to distant site. Frequent sites are lung, regional lymph node, bone, and adrenal gland. But metastasis to the gastrointestinal (GI) tract is rare, and most common site is stomach. Metastasis to the small intes...

journal_title：World journal of gastroenterology

authors： Kim HS,Shin JW,Kim GY,Kim YM,Cha HJ,Jeong YK,Jeong ID,Bang SJ,Kim DH,Park NH

更新日期：2006-03-28 00:00:00

abstract：AIM:To explore the relationship between α-fetoprotein (AFP) and various clinicopathological variables and different staging system of hepatocellular carcinoma (HCC) thoroughly. METHODS:A retrospective cohort study of consecutive patients diagnosed with HCC between January 2008 and December 2009 in West China Hospital ...

journal_title：World journal of gastroenterology

authors： Liu C,Xiao GQ,Yan LN,Li B,Jiang L,Wen TF,Wang WT,Xu MQ,Yang JY

更新日期：2013-03-21 00:00:00

abstract：AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

journal_title：World journal of gastroenterology

authors： Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

更新日期：2011-09-21 00:00:00

abstract：AIM:To explore dysregulation of c-fos in several human malignancies, and to further investigate the role of c-fos in Helicobacter pylori (H. pylori)-induced gastric precancerosis. METHODS:Four-week-old male Mongolian gerbils were employed in the study. 0.5 mL 1X10(8) cfu/L suspension of H. pylori NCTC 11 637 in Brucel...

journal_title：World journal of gastroenterology

authors： Yang YL,Xu B,Song YG,Zhang WD

更新日期：2003-03-01 00:00:00

abstract：AIM:To study the effect of IGF-1/IGF-1R and gastrin/CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS:mRNA expression levels of IGF-1/IGF-1R and gastrin/C...

journal_title：World journal of gastroenterology

authors： Zhao MD,Hu XM,Sun DJ,Zhang Q,Zhang YH,Meng W

更新日期：2005-06-07 00:00:00

abstract：AIM:To evaluate the best diagnostic technique and risk factors of the human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) infection in inflammatory bowel disease (IBD). METHODS:A cohort of 40 IBD patients (17 refractory) and 40 controls underwent peripheral blood and endoscopic colonic mucosal sample harvest. Vi...

journal_title：World journal of gastroenterology

authors： Ciccocioppo R,Racca F,Paolucci S,Campanini G,Pozzi L,Betti E,Riboni R,Vanoli A,Baldanti F,Corazza GR

更新日期：2015-02-14 00:00:00

abstract：:Unspecific abdominal complaints including bloating and irregular bowel movements may be caused by carbohydrate malabsorption syndromes, e.g., lactose and fructose malabsorption. These symptoms were investigated with hydrogen (H2) breath tests and correlated to carbohydrate malabsorption. During performing these H2-bre...

journal_title：World journal of gastroenterology

authors： Schnedl WJ,Kalmar P,Mangge H,Krause R,Wallner-Liebmann SJ

更新日期：2015-09-21 00:00:00

abstract：AIM:To determine factors associated with fibrosis progression in hepatitis C virus (HCV)-infected patients without significant initial pathological lesions. METHODS:Seventy six untreated HCV-infected patients with initially normal liver as defined by a Knodell score < or = 3, with 2 liver biopsies and detectable HCV-R...

journal_title：World journal of gastroenterology

authors： Sobesky R,Lebray P,Nalpas B,Vallet-Pichard A,Fontaine H,Lagneau JL,Pol S

更新日期：2008-06-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) produce an enzyme known as γ-glutamyl transpeptidase (HpGGT) that is highly conserved and common to all strains. HpGGT has been gaining increasing attention as an important virulence factor of the bacterium, having been demonstrated to be an important colonization factor in several anim...

journal_title：World journal of gastroenterology

authors： Ling SS,Yeoh KG,Ho B

更新日期：2013-12-07 00:00:00

abstract：:An 85 year male patient complaining epigastric discomfort was admitted. From the esophagogastroduodenoscopy, three early gastric cancer (EGCa) lesions had been identified and these were diagnosed as adenocarcinoma with poorly differentiated cell type. The patient underwent operation. From the post-operative mapping, h...

journal_title：World journal of gastroenterology

authors： Seong H,Kim JI,Lee HJ,Kim HJ,Cho HJ,Kim HK,Cheung DY,Kim DJ,Kim W,Kim TJ

更新日期：2013-11-28 00:00:00

abstract：BACKGROUND:Incidence and severity variations of inflammatory bowel disease (IBD) have been reported from Western populations between continents and regions of the same countries. However, no data were available from other countries. AIM:To investigate the regional differences in the IBD profiles of pediatric patients ...

journal_title：World journal of gastroenterology

authors： El Mouzan MI,AlEdreesi MH,Hasosah MY,Al-Hussaini AA,Al Sarkhy AA,Assiri AA

更新日期：2020-01-28 00:00:00

abstract：AIM:To explore the impact of prolonged fraction dose-delivery time modeling intensity-modulated radiation therapy (IMRT) on cell killing of human hepatocellular carcinoma (HCC) HepG2 and Hep3B cell lines. METHODS:The radiobiological characteristics of human HCC HepG2 and Hep3b cell lines were studied with standard clo...

journal_title：World journal of gastroenterology

authors： Zheng XK,Chen LH,Yan X,Wang HM

更新日期：2005-03-14 00:00:00