Endoscopic ultrasound-guided choledochoduodenostomies with fully covered self-expandable metallic stents.


AIM:To investigate the long-term outcomes of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) with a fully covered self-expandable metallic stent (FCSEMS). METHODS:From April 2009 to August 2010, 15 patients with distal malignant biliary obstructions who were candidates for alternative techniques for biliary decompression due to a failed endoscopic retrograde cholangiopancreatography (ERCP) were included. These 15 patients consisted of 8 men and 7 women and had a median age of 61 years (range: 30-91 years). The underlying causes of the distal malignant biliary obstruction were pancreatic cancer (n = 9), ampulla of Vater cancer (n = 2), renal cell carcinoma (n = 1), advanced gastric cancer (n = 1), lymphoma (n = 1), and duodenal cancer (n = 1). RESULTS:The technical success rate of EUS-CDS with an FCSEMS was 86.7% (13/15), and functional success was achieved in 100% (13/13) of those cases. In two patients, the EUS-CDS failed because an FCSEMS with a delivery device could not be passed into the common bile duct. The mean duration of stent patency was 264 d. Early adverse events developed in three patients (3/13, 23.1%), including self-limited pneumoperitoneum in two patients and cholangitis requiring stent reposition in one patient. During the follow-up period (median: 186 d, range: 52-388 d), distal stent migration occurred in four patients (4/13, 30.8%). In 3 patients, the FCSEMS could be reinserted through the existing choledochoduodenal fistula tract. CONCLUSION:EUS-CDS with an FCSEMS is technically feasible and can lead to effective palliation of distal malignant biliary obstructions after failed ERCP.


World J Gastroenterol


Song TJ,Hyun YS,Lee SS,Park DH,Seo DW,Lee SK,Kim MH




Has Abstract


2012-08-28 00:00:00












  • Long-term leukocyte natural α-interferon and ribavirin treatment in hepatitis C virus recurrence after liver transplantation.

    abstract:AIM:To evaluate the effect of long-term treatment with leukocyte natural α-interferon (ln-α-IFN) plus ribavirin (RBV). METHODS:Forty-six patients with hepatitis C virus (HCV) recurrence received 3 MU three times a week of ln-α-IFN plus RBV for 1 mo; then, patients with good tolerability (n = 30) were switched to daily...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Tamè M,Buonfiglioli F,Del Gaudio M,Lisotti A,Cecinato P,Colecchia A,Azzaroli F,D'Errico A,Arena R,Calvanese C,Quarneti C,Ballardini G,Pinna AD,Mazzella G

    更新日期:2013-08-28 00:00:00

  • Difficulty in differentiating two cases of sigmoid stenosis by diverticulitis from cancer.

    abstract::The incidence of colonic diverticulosis with or without diverticulitis has increased in the Japanese population due to the modernization of food and aging. The rate of diverticulitis in colon diverticulosis ranges from 8.1% to 9.6%. However, few cases of stenosis due to diverticulitis have been reported. These reports...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Nishiyama N,Mori H,Kobara H,Rafiq K,Fujihara S,Kobayashi M,Masaki T

    更新日期:2012-07-21 00:00:00

  • Clinical characteristics and prognostic factors of splenic abscess: a review of 67 cases in a single medical center of Taiwan.

    abstract:AIM:To analyze 67 cases of splenic abscess in a medical center of Taiwan during a period of 19 years. METHODS:From January 1986 to December 2004, a total of 67 patients with splenic abscess were enrolled for the retrospective study. The clinical characteristics, underlying diseases, organism spectra, therapeutic metho...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Chang KC,Chuah SK,Changchien CS,Tsai TL,Lu SN,Chiu YC,Chen YS,Wang CC,Lin JW,Lee CM,Hu TH

    更新日期:2006-01-21 00:00:00

  • Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma.

    abstract:AIM:To investigate the role of neoadjuvant chemoradiotherapy in prognosis and surgery for esophageal carcinoma by a meta-analysis. METHODS:PubMed and manual searches were done to identify all published randomized controlled trials (RCTs) that compared neoadjuvant chemoradiotherapy plus surgery (CRTS) with surgery alon...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审


    authors: Lv J,Cao XF,Zhu B,Ji L,Tao L,Wang DD

    更新日期:2009-10-21 00:00:00

  • Modified technique for combined liver-small bowel transplantation in pigs.

    abstract:AIM:As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Yin ZY,Ni XD,Jiang F,Li N,Li YS,Li JS

    更新日期:2003-07-01 00:00:00

  • Hexahydrocurcumin enhances inhibitory effect of 5-fluorouracil on HT-29 human colon cancer cells.

    abstract:AIM:To investigate the ability of hexahydrocurcumin (HHC) to enhance 5-fluorouracil (5-FU) in inhibiting the growth of HT-29 cells by focusing on cyclooxygenase (COX)-2 expression. METHODS:Antiproliferative effects of HHC and 5-FU, alone and in combination, on growth of HT-29 human colon cancer cells were assessed usi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Srimuangwong K,Tocharus C,Yoysungnoen Chintana P,Suksamrarn A,Tocharus J

    更新日期:2012-05-21 00:00:00

  • Endoscopic treatment of chronic pancreatitis.

    abstract::Treatment of chronic pancreatitis has been exclusively surgical for a long time. Recently, endoscopic therapy has become widely used as a primary therapeutic option. Initially performed for drainage of pancreatic cysts and pseudocysts, endoscopic treatments were adapted to biliary and pancreatic ducts stenosis. Pancre...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审


    authors: Heyries L,Sahel J

    更新日期:2007-12-14 00:00:00

  • Experimental study on therapeutic effect of in vivo expression of Cell I-Hep II recombinant polypeptide of fibronectin on murine H22 hepatocellular carcinoma.

    abstract:AIM:To investigate the inhibitory effect of in vivo expression of expressing plasmid pCH510 of recombinant fibronectin polypeptide (CH50) on hepatocellular carcinoma and the improved therapeutic effect of pCH510 in combination with chemotherapeutic agents and Hsp70-H22 hepatocarcinoma antigen peptide on tumor. METHODS...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhang GM,Yang Y,Huang B,Xiao H,Li D,Feng ZH

    更新日期:2003-09-01 00:00:00

  • Expression of pituitary homeobox 1 gene in human gastric carcinogenesis and its clinicopathological significance.

    abstract:AIM:To investigate the effect of pituitary homeobox 1 (PITX1) expression in cases of human gastric cancer on cancer differentiation and progression, and carcinogenesis. METHODS:Using polyclonal PITX1 antibodies, we studied the expression of PITX1 in normal gastric mucosa, atypical hyperplasia, intestinal metaplasia, a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Chen YN,Chen H,Xu Y,Zhang X,Luo Y

    更新日期:2008-01-14 00:00:00

  • Bile acid increases expression of the histamine-producing enzyme, histidine decarboxylase, in gastric cells.

    abstract:AIM:To investigate the effect of bile acid on the expression of histidine decarboxylase (HDC), which is a major enzyme involved in histamine production, and gene expression of gastric transcription factors upon cooperative activation. METHODS:HDC expression was examined by immunohistochemistry, reverse transcriptase p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Ku HJ,Kim HY,Kim HH,Park HJ,Cheong JH

    更新日期:2014-01-07 00:00:00

  • Thinking outside the liver: induced pluripotent stem cells for hepatic applications.

    abstract::The discovery of induced pluripotent stem cells (iPSCs) unraveled a mystery in stem cell research, after identification of four re-programming factors for generating pluripotent stem cells without the need of embryos. This breakthrough in generating iPSCs from somatic cells has overcome the ethical issues and immune r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Subba Rao M,Sasikala M,Nageshwar Reddy D

    更新日期:2013-06-14 00:00:00

  • Successful resection of metachronous para-aortic, Virchow lymph node and liver metastatic recurrence of rectal cancer.

    abstract::A 66-year-old female presented with the main complaint of defecation trouble and abdominal distention. With diagnosis of rectal cancer, cSS, cN0, cH0, cP0, cM0 cStage II, Hartmann's operation with D3 lymph node dissection was performed and a para-aortic lymph node and a disseminated node near the primary tumor were re...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Takeshita N,Fukunaga T,Kimura M,Sugamoto Y,Tasaki K,Hoshino I,Ota T,Maruyama T,Tamachi T,Hosokawa T,Asai Y,Matsubara H

    更新日期:2015-11-28 00:00:00

  • Repeat endoscopic retrograde cholangiopancreaticography after failed initial precut sphincterotomy for biliary cannulation.

    abstract:AIM:To investigate the outcome of repeating endoscopic retrograde cholangiopancreaticography (ERCP) after initially failed precut sphincterotomy to achieve biliary cannulation. METHODS:In this retrospective study, consecutive ERCPs performed between January 2009 and September 2012 were included. Data from our endoscop...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Pavlides M,Barnabas A,Fernandopulle N,Bailey AA,Collier J,Phillips-Hughes J,Ellis A,Chapman R,Braden B

    更新日期:2014-09-28 00:00:00

  • Multi-disciplinary treatment for cholangiocellular carcinoma.

    abstract::Cholangiocarcinoma (CC) is rare malignant tumors composed of cells that resemble those of the biliary tract. It is notoriously difficult to diagnose, and is associated with a high mortality. Traditionally, CC is divided into intrahepatic and extrahepatic disease according to its location within the biliary tree. Intra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Shimoda M,Kubota K

    更新日期:2007-03-14 00:00:00

  • Pneumatosis cystoides intestinalis after fluorouracil chemotherapy for rectal cancer.

    abstract::Pneumatosis cystoides intestinalis (PCI) is a relatively rare condition characterized by intraluminal gas in the gastrointestinal tract. Several chemotherapeutic agents have been reported to be associated with PCI, although fluorouracil-related PCI is extremely rare. We report a case of a 76-year old man who received ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Mimatsu K,Oida T,Kawasaki A,Kano H,Kuboi Y,Aramaki O,Amano S

    更新日期:2008-05-28 00:00:00

  • The prognostic significance of clinical and pathological features in hepatocellular carcinoma.

    abstract::The prognosis of patients with HCC still remains dismal. The life expectancy of HCC patients is hard to predict because of the high possibility of postoperative recurrence. Many factors, such as patient's general conditions, macroscopic tumor morphology, as well as tumor histopathology features, have been proven of pr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Qin LX,Tang ZY

    更新日期:2002-04-01 00:00:00

  • Is aggressive intravenous fluid resuscitation beneficial in acute pancreatitis? A meta-analysis of randomized control trials and cohort studies.

    abstract:BACKGROUND:There is conflincting evidence on the intravenous fluid (IVF) strategy for acute pancreatitis (AP). We perform a metaanalysis of the available evidence. AIM:To investigate if aggressive IVF therapy in AP patients is beneficial to decrease mortality and improve outcomes. METHODS:Metaanalysis of available ra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审


    authors: Gad MM,Simons-Linares CR

    更新日期:2020-03-14 00:00:00

  • Percentage of peak-to-peak pulsatility of portal blood flow can predict right-sided congestive heart failure.

    abstract:AIM:To study the change of portal blood flow for the prediction of the status of right-sided heart failure by using non-invasive way. METHODS:We studied 20 patients with rheumatic and atherosclerotic heart diseases. All the patients had constant systemic blood pressure and body weight 1 week prior to the study. Cardia...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Hu JT,Yang SS,Lai YC,Shih CY,Chang CW

    更新日期:2003-08-01 00:00:00

  • Effect of probiotics on pro-inflammatory cytokines and NF-kappaB activation in ulcerative colitis.

    abstract:AIM:To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis (UC), and their effect on inflammatory mediators and nuclear factor (NF)-kappaB activation in these patients. METHODS:Thirty patients with mild to moderate UC were randomly classified into two groups: sulfasalazine group, who r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验


    authors: Hegazy SK,El-Bedewy MM

    更新日期:2010-09-07 00:00:00

  • Evolution and future of laparoscopic colorectal surgery.

    abstract::The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Kaiser AM

    更新日期:2014-11-07 00:00:00

  • Effect of extended radical resection for rectal cancer.

    abstract:AIM:To discuss the rationality of extended radical resection (ERR) and to guide the surgical treatment of rectal cancer. METHODS:Total 211 patients who underwent ERR from 1981 to 1987 (follow-up rate of 94.8 %) were selected to study the patterns of lymphatic metastasis and therapeutic effect. The control group was ma...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Dong XS,Xu HT,Yu ZW,Liu M,Cu BB,Zhao P,Wang XS

    更新日期:2003-05-01 00:00:00

  • Liver-related effects of chronic hepatitis C antiviral treatment.

    abstract::More than five years ago, the treatment of hepatitis C virus infection was revolutionized with the introduction of all-oral direct-acting antiviral (DAA) drugs. They proved highly efficient in curing patients with chronic hepatitis C (CHC), including patients with cirrhosis. The new DAA treatments were alleged to indu...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Laursen TL,Sandahl TD,Kazankov K,George J,Grønbæk H

    更新日期:2020-06-14 00:00:00

  • Expression, deletion [was deleton] and mutation of p16 gene in human gastric cancer.

    abstract:AIM:To investigate the relationship between the expression of p16 gene and the gastric carcinogenesis, depth of invasion and lymph node metastases, and to evaluate the deletion and mutation of exon 2 in p16 gene in gastric carcinoma. METHODS:The expression of p16 protein was examined by streptavidin-peroxidase conjuga...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: He XS,Su Q,Chen ZC,He XT,Long ZF,Ling H,Zhang LR

    更新日期:2001-08-01 00:00:00

  • Rate of adverse events of gastroduodenal snare polypectomy for non-flat polyp is low: A prospective and multicenter study.

    abstract:AIM:To evaluate the rate of adverse events (AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers. METHODS:Polypectomies of protruded gastric or duodenal polyps ≥ 5 mm using hot snare were prospectively included. Prophylactic measures of hemorrhage were allowed in predefined cases. AEs ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究


    authors: Córdova H,Argüello L,Loras C,Naranjo Rodríguez A,Riu Pons F,Gornals JB,Nicolás-Pérez D,Andújar Murcia X,Hernández L,Santolaria S,Leal C,Pons C,Pérez-Cuadrado-Robles E,García-Bosch O,Papo Berger M,Ulla Rocha JL,Sánchez-Mon

    更新日期:2017-12-21 00:00:00

  • Clinical presentation and genotype of hepatitis delta in Karachi.

    abstract:AIM:To assess the clinical presentation and genotypes of delta hepatitis in local population. METHODS:In this prospective study, 39 consecutive patients who were positive for HBsAg and hepatitis D virus (HDV) antibody were included. The patients were divided in two groups on the basis of presence or absence of HDV RNA...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Moatter T,Abbas Z,Shabir S,Jafri W

    更新日期:2007-05-14 00:00:00

  • Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.

    abstract:AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

    更新日期:2005-05-07 00:00:00

  • Prospective study of scoring system in selective intraoperative cholangiography during laparoscopic cholecystectomy.

    abstract:AIM:To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC). METHODS:The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Sun XD,Cai XY,Li JD,Cai XJ,Mu YP,Wu JM

    更新日期:2003-04-01 00:00:00

  • Current research and treatment for gastrointestinal stromal tumors.

    abstract::Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and have gained considerable research and treatment interest, especially in the last two decades. GISTs are driven by mutations commonly found in the KIT gene and less commonly in the platelet-derived growth fa...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审


    authors: Lim KT,Tan KY

    更新日期:2017-07-21 00:00:00

  • Irsogladine maleate suppresses indomethacin-induced elevation of proinflammatory cytokines and gastric injury in rats.

    abstract:AIM:To investigate the mucosal protective effect and the mechanisms of action of the anti-ulcer drug irsogladine maleate in gastric injury induced by indomethacin in rats. METHODS:Gastric mucosal injury was induced in male Hos:Donryu rats by oral administration of indomethacin at a dose of 48 mg/kg. One hour before in...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhang X,Tajima K,Kageyama K,Kyoi T

    更新日期:2008-08-14 00:00:00

  • Autoantibodies against MMP-7 as a novel diagnostic biomarker in esophageal squamous cell carcinoma.

    abstract:AIM:To evaluate the diagnostic values of serum autoantibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoantibodies were then measur...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhou JH,Zhang B,Kernstine KH,Zhong L

    更新日期:2011-03-14 00:00:00