Abstract:
AIM:To identify the actual clinical management and associated factors of delayed perforation after gastric endoscopic submucosal dissection (ESD). METHODS:A total of 4943 early gastric cancer (EGC) patients underwent ESD at our hospital between January 1999 and June 2012. We retrospectively assessed the actual management of delayed perforation. In addition, to determine the factors associated with delayed perforation, after excluding 123 EGC patients with perforations that occurred during the ESD procedure, we analyzed the following clinicopathological factors among the remaining 4820 EGC patients by comparing the ESD cases with delayed perforation and the ESD cases without perforation: age, sex, chronological periods, clinical indications for ESD, status of the stomach, location, gastric circumference, tumor size, invasion depth, presence/absence of ulceration, histological type, type of resection, and procedure time. RESULTS:Delayed perforation occurred in 7 (0.1%) cases. The median time until the occurrence of delayed perforation was 11 h (range, 6-172 h). Three (43%) of the 7 cases required emergency surgery, while four were conservatively managed without surgical intervention. Among the 4 cases with conservative management, 2 were successfully managed endoscopically using the endoloop-endoclip technique. The median hospital stay was 18 d (range, 15-45 d). There were no delayed perforation-related deaths. Based on a multivariate analysis, gastric tube cases (OR = 11.0; 95%CI: 1.7-73.3; P = 0.013) were significantly associated with delayed perforation. CONCLUSION:Endoscopists must be aware of not only the identified factors associated with delayed perforation, but also how to treat this complication effectively and promptly.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Suzuki H,Oda I,Sekiguchi M,Abe S,Nonaka S,Yoshinaga S,Nakajima T,Saito Ydoi
10.3748/wjg.v21.i44.12635subject
Has Abstractpub_date
2015-11-28 00:00:00pages
12635-43issue
44eissn
1007-9327issn
2219-2840journal_volume
21pub_type
杂志文章abstract:AIM:To assess the efficacy and safety of TECA type hybrid artificial liver support system (TECA-HALSS) in providing liver function of detoxification, metabolism and physiology by treating the patients with acute liver failure (ALF). METHODS:The porcine liver cells (1-2) x 10(10) were separated from the Chinese small s...
journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v7.i6.826
更新日期:2001-12-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v4.i3.222
更新日期:1998-06-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v21.i6.1845
更新日期:2015-02-14 00:00:00
abstract::Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...
journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v19.i44.7867
更新日期:2013-11-28 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-09-28 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v11.i28.4396
更新日期:2005-07-28 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.14.3579
更新日期:2008-06-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v11.i14.2136
更新日期:2005-04-14 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2020-03-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.3273
更新日期:2008-05-28 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v12.i10.1630
更新日期:2006-03-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v10.i4.579
更新日期:2004-02-15 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v7.i2.198
更新日期:2001-04-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v6.i5.659
更新日期:2000-10-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2009-07-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v8.i6.1134
更新日期:2002-12-01 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v16.i21.2600
更新日期:2010-06-07 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2014-02-28 00:00:00
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pub_type: 杂志文章
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更新日期:2004-03-15 00:00:00
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pub_type: 杂志文章
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更新日期:2019-03-14 00:00:00
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journal_title:World journal of gastroenterology
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更新日期:2017-04-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2009-02-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2016-06-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2006-11-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2005-02-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v17.i2.181
更新日期:2011-01-14 00:00:00