Point-of-care testing in the diagnosis of gastrointestinal cancers: current technology and future directions.

abstract：AIM:To detect linc00675 expression in pancreatic ductal adenocarcinoma (PDAC), to analyze the relationship between the expression level of linc00675 and the clinical pathological characteristics, to explore the biological functions of linc00675, and to determine whether linc00675 has independent prognostic value in PDA...

journal_title：World journal of gastroenterology

authors： Li DD,Fu ZQ,Lin Q,Zhou Y,Zhou QB,Li ZH,Tan LP,Chen RF,Liu YM

更新日期：2015-08-21 00:00:00

abstract：AIM:CMU-1 is a new preservation solution with a low potassium concentration as well as low viscosity that is highly effective in reducing preservation injury. The purpose of this experiment is to compare the protective effect of CMU-1 solution with that of UW during cold preservation and normothermic reperfusion. METH...

journal_title：World journal of gastroenterology

authors： Cheng Y,Liu YF,Cheng DH,Li BF,Zhao N

更新日期：2005-04-28 00:00:00

abstract：:Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor (GIST) in the stomach is uncommon. Only rare cases have been reported in the literature. We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22...

journal_title：World journal of gastroenterology

authors： Mou YP,Xu XW,Xie K,Zhou W,Zhou YC,Chen K

更新日期：2010-10-21 00:00:00

abstract：AIM:To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients. METHODS:In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria...

journal_title：World journal of gastroenterology

authors： Appel-da-Silva MC,Miozzo SA,Dossin IA,Tovo CV,Branco F,de Mattos AA

更新日期：2016-12-14 00:00:00

abstract：AIM:To develop an algorithm to improve the diagnosis and treatment of patients with biliary candidiasis. METHODS:We performed a prospective study of 127 patients who underwent endoscopic retrograde cholangiopancreatography, for various biliary disorders, at 3 tertiary referral centers in Germany from July 2011 through...

journal_title：World journal of gastroenterology

authors： Lenz P,Eckelskemper F,Erichsen T,Lankisch T,Dechêne A,Lubritz G,Lenze F,Beyna T,Ullerich H,Schmedt A,Domagk D

更新日期：2014-09-14 00:00:00

abstract：AIM:To evaluate the efficacy of Stretta procedure with gastroesophageal reflux disease (GERD) based on symptom control, medication changes and oesophagitis grade. METHODS:Ninety patients with a history of GERD underwent Stretta procedure from June 2007 to March 2010. All patients with GERD diagnosed by the presence of...

journal_title：World journal of gastroenterology

authors： Liu HF,Zhang JG,Li J,Chen XG,Wang WA

更新日期：2011-10-21 00:00:00

abstract：AIM:This retrospective study was designed to analyze the results and the failure patterns of late course accelerated hyperfractionated radiotherapy for clinical T(1-2)N(0)M(0) esophageal carcinoma. METHODS:From Aug. 1994 to Feb. 2001, 56 patients with clinical T(1-2) esophageal carcinoma received late course accelerat...

journal_title：World journal of gastroenterology

authors： Zhao KL,Wang Y,Shi XH

更新日期：2003-06-01 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：AIM:To evaluate the proinflammatory effects and molecular mechanisms of interleukin (IL)-17 in intestinal epithelial cell line HT-29. METHODS:HT-29 cells were cultured with IL-17, tumor necrosis factor (TNF)-α, or the combination of both IL-17 and TNF-α. Real-time PCR and Western blot were used to measure the gene exp...

journal_title：World journal of gastroenterology

authors： Wang YL,Fang M,Wang XM,Liu WY,Zheng YJ,Wu XB,Tao R

更新日期：2014-12-21 00:00:00

abstract：AIM:To explore the correlation between expression of somatostatin (SS), gastrin (GAS) and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. METHODS:Sixty-two large intestine cancer tissue samples were randomly and retrospectively selected from patients with large intestine carcinoma. Immunohistoch...

journal_title：World journal of gastroenterology

authors： Mao JD,Wu P,Xia XH,Hu JQ,Huang WB,Xu GQ

更新日期：2005-02-07 00:00:00

abstract：AIM:To evaluate the effects of omeprazole on gastric mechanosensitivity in humans. METHODS:A double lumen polyvinyl tube with a plastic bag was introduced into the stomach of healthy volunteers under fluorography and connected to a barostat device. Subjects were then positioned so they were sitting comfortably, and th...

journal_title：World journal of gastroenterology

authors： Iida A,Kaneko H,Konagaya T,Funaki Y,Tokudome K,Izawa S,Tamura Y,Mizuno M,Ogasawara N,Sasaki M,Kasugai K

更新日期：2012-10-21 00:00:00

abstract：:Over the last 15 years, there have been major advances in the multimodal treatment of gastric cancer, in large part due to several phase III studies showing the treatment benefits of neoadjuvant and adjuvant chemotherapy and chemoradiation protocols. The objective of this editorial is to review the current high-level ...

journal_title：World journal of gastroenterology

authors： Choi AH,Kim J,Chao J

更新日期：2015-06-28 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

journal_title：World journal of gastroenterology

authors： Lazaraki G,Chatzimavroudis G,Katsinelos P

更新日期：2014-07-21 00:00:00

abstract：:Microsatellite instability (MSI) is a prognostic factor and a marker of deficient mismatch repair (MMR) in colorectal adenocarcinomas (CRC). However, a proper application of this marker requires understanding the following: (1) The MSI concept: The PCR approach must amplify the correct locus and accurately identify th...

journal_title：World journal of gastroenterology

authors： Blanes A,Diaz-Cano SJ

更新日期：2006-10-07 00:00:00

abstract：:A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

journal_title：World journal of gastroenterology

authors： Chen Y,Ma WQ,Chen JM,Cai JT

更新日期：2010-02-14 00:00:00

abstract：AIM:To globally compare the gene expression profiles during the capillary morphogenesis of human microvascular endothelial cells (HMVECs) in an in vitro angiogenesis system with affymetrix oligonucleotide array. METHODS:A microcarrier-based in vitro angiogenesis system was developed, in which ECs migrated into the mat...

journal_title：World journal of gastroenterology

authors： Sun XT,Zhang MY,Shu C,Li Q,Yan XG,Cheng N,Qiu YD,Ding YT

更新日期：2005-04-21 00:00:00

abstract：AIM:To summarize the performing essentials and analyze the characteristics of remote Zeus robot-assisted laparoscopic cholecystectomy. METHODS:Robot-assisted laparoscopic cholecystectomy was performed in 40 patients between May 2004 and July 2005. The operating procedures and a variety of clinical parameters were reco...

journal_title：World journal of gastroenterology

authors： Zhou HX,Guo YH,Yu XF,Bao SY,Liu JL,Zhang Y,Ren YG,Zheng Q

更新日期：2006-04-28 00:00:00

abstract：AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

journal_title：World journal of gastroenterology

authors： Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

更新日期：2008-11-14 00:00:00

abstract：:Oncological treatment is currently directed toward a tailored therapy concept. Squamous cell carcinoma of the anal canal could be considered a suitable platform to test new therapeutic strategies to minimize treatment morbidity. Standard of care for patients with anal canal cancer consists of a combination of radiothe...

journal_title：World journal of gastroenterology

authors： De Nardi P,Carvello M,Staudacher C

更新日期：2012-11-28 00:00:00

abstract：:Despite advancements in medical therapy of Crohn's disease (CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for sur...

journal_title：World journal of gastroenterology

authors： Toh JW,Stewart P,Rickard MJ,Leong R,Wang N,Young CJ

更新日期：2016-10-28 00:00:00

abstract：AIM:To quantify the impact of split-dose regimen on endoscopists' compliance with guideline recommendations for timing of repeat colonoscopy in patients with normal colonoscopy or 1-2 small polyps (< 10 mm). METHODS:A retrospective chart review of all endoscopy reports was undertaken in average-risk individuals > 50 y...

journal_title：World journal of gastroenterology

authors： Menees SB,Kim HM,Schoenfeld P

更新日期：2018-02-14 00:00:00

abstract：AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

journal_title：World journal of gastroenterology

authors： An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

更新日期：2018-08-07 00:00:00

abstract：AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

journal_title：World journal of gastroenterology

authors： Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

更新日期：2018-08-14 00:00:00

abstract：AIM:To compare ghrelin levels in plasma and gastric mucosa before and after Helicobacter pylori (H. pylori) treatment in children with H. pylori-associated functional dyspepsia. METHODS:Children with H. pylori-associated functional dyspepsia were enrolled in this study. H. pylori infection was confirmed by positive ba...

journal_title：World journal of gastroenterology

authors： Deng ZH,Chu B,Xu YZ,Zhang B,Jiang LR

更新日期：2012-09-28 00:00:00

abstract：AIM:To determine serum vitamin D levels and colonic vitamin D receptor (VDR) expression in inflammatory bowel disease (IBD) and non-IBD patients and correlate these with histopathology. METHODS:Puerto Rican IBD (n = 10) and non-IBD (n = 10) patients ≥ 21 years old scheduled for colonoscopy were recruited. Each patient...

journal_title：World journal of gastroenterology

authors： Abreu-Delgado Y,Isidro RA,Torres EA,González A,Cruz ML,Isidro AA,González-Keelan CI,Medero P,Appleyard CB

更新日期：2016-04-07 00:00:00

abstract：AIM:To analyze, retrospectively in a population-based study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS:All rectal carcinomas diagnosed during 1998 to 2000 and initially treated w...

journal_title：World journal of gastroenterology

authors： Bakx R,Visser O,Josso J,Meijer S,Slors JF,van Lanschot JJ

更新日期：2008-10-21 00:00:00

abstract：:Crohn's disease (CD) is a multifactorial disorder of unknown cause. Outstanding progress regarding the pathophysiology of CD has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD over the last years. However, many drugs have not been approved by regulatory ...

journal_title：World journal of gastroenterology

authors： Büning C,Lochs H

更新日期：2006-08-14 00:00:00

abstract：:Cholangiocarcinoma is the second most common primary hepatic cancer. Despite advances in diagnostic techniques during the past decade, cholangiocarcinoma is usually encountered at an advanced stage. In this review, we describe the classification, diagnosis, and initial management of cholangiocarcinoma with obstructive...

journal_title：World journal of gastroenterology

authors： Tajiri T,Yoshida H,Mamada Y,Taniai N,Yokomuro S,Mizuguchi Y

更新日期：2008-05-21 00:00:00

abstract：AIM:To explore the impact of prolonged fraction dose-delivery time modeling intensity-modulated radiation therapy (IMRT) on cell killing of human hepatocellular carcinoma (HCC) HepG2 and Hep3B cell lines. METHODS:The radiobiological characteristics of human HCC HepG2 and Hep3b cell lines were studied with standard clo...

journal_title：World journal of gastroenterology

authors： Zheng XK,Chen LH,Yan X,Wang HM

更新日期：2005-03-14 00:00:00

abstract：AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

journal_title：World journal of gastroenterology

authors： Ding LA,Li JS

更新日期：2003-06-01 00:00:00