当前位置： SCI文献检索 > HISTOPATHOLOGY期刊下所有文献 > Punch 'scoring': a technique that facilitates melanoma diagnosis of clinically suspicious pigmented lesions.

Punch 'scoring': a technique that facilitates melanoma diagnosis of clinically suspicious pigmented lesions.

Abstract：

AIMS:Early recognition and accurate diagnosis underpins melanoma survival. Identifying early melanomas arising in association with pre-existing lesions is often challenging. Clinically suspicious foci, however small, must be identified and examined histologically. This study assessed the accuracy of punch biopsy 'scoring' of suspicious foci in excised atypical pigmented skin lesions to identify early melanomas. METHODS AND RESULTS:Forty-one excised pigmented skin lesions with a clinically/dermoscopically focal area of concern for melanoma, with the suspicious focus marked prior to excision with a punch biopsy 'score' (a partial incision into the skin surface), were analysed. Melanoma was diagnosed in nine of 41 cases (22%). In eight of nine cases (89%) the melanoma was associated with a naevus, and in seven of nine (88%) cases the melanoma was identified preferentially by the scored focus. In six of nine cases (67%), the melanoma was entirely encompassed by the scored focus. In one case of melanoma in situ, the diagnostic material was identified only on further levelling through the scored focus. In 28 of 32 of non-melanoma cases (88%), the scored focus identified either diagnostic features of a particular lesion or pathological features that correlated with the clinical impression of change/atypia including altered architecture or distribution of pigmentation, features of irritation or regression. CONCLUSIONS:The 'punch scoring technique' allows direct clinicopathological correlation and facilitates early melanoma diagnosis by focusing attention on clinically suspicious areas. Furthermore, it does not require special expertise in ex-vivo clinical techniques for implementation. Nevertheless, in some cases examination of the lesion beyond the scored focus is also necessary to make a diagnosis of melanoma.

journal_name

Histopathology

journal_title

Histopathology

authors

Grogan J,Cooper CL,Dodds TJ,Guitera P,Menzies SW,Scolyer RA

doi

10.1111/his.13342

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

294-304

issue

2

eissn

0309-0167

issn

1365-2559

journal_volume

72

pub_type

杂志文章

相关文献

HISTOPATHOLOGY文献大全
  • Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular carcinoma from cholangiocarcinoma, combined tumours and metastatic carcinoma.

    abstract：AIMS:To examine the usefulness of Hep Par 1 together with selected antibodies in the separation of hepatocellular carcinoma (HCC) from cholangiocarcinoma (CC), combined tumours (HCC-CC) and metastatic carcinoma. METHODS AND RESULTS:Antibodies to Hep Par 1, CK19, CK20 and factor XIIIa were applied to 32 HCCs, 27 CCs, f...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1046/j.1365-2559.1998.00522.x

    authors： Leong AS,Sormunen RT,Tsui WM,Liew CT

    更新日期：1998-10-01 00:00:00

  • The role of Helicobacter pylori in primary gastric MALT lymphoma.

    abstract：AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1046/j.1365-2559.1999.00597.x

    authors： Bouzourene H,Haefliger T,Delacretaz F,Saraga E

    更新日期：1999-02-01 00:00:00

  • Epstein-Barr virus (EBV)-associated undifferentiated carcinoma of the parotid gland.

    abstract：:A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.1988.tb02075.x

    authors： Huang DP,Ng HK,Ho YH,Chan KM

    更新日期：1988-11-01 00:00:00

  • Nephroblastoma with fibroadenomatous-like structures.

    abstract：:Review of the histological sections of the tumours of 889 patients from the files of the SIOP Nephroblastoma trials and studies has revealed 23 cases with a distinctive growth pattern. Due to the similarity of the histological structures with the architecture of adenofibroma (fibroadenoma) of the ovary we have called ...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.1984.tb02321.x

    authors： Delemarre JF,Sandstedt B,Tournade MF

    更新日期：1984-01-01 00:00:00

  • Loss of succinate dehydrogenase B immunohistochemical expression distinguishes pulmonary chondromas from hamartomas.

    abstract：AIMS:Pulmonary chondromas, which are rare cartilaginous neoplasms that often arise in the setting of Carney triad, are morphologically similar to pulmonary hamartomas, which are much more common. There is evidence that succinate dehydrogenase (SDH) deficiency drives neoplasia in patients with Carney triad, and SDHB imm...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.13945

    authors： Chatzopoulos K,Fritchie KJ,Aubry MC,Carney JA,Folpe AL,Boland JM

    更新日期：2019-12-01 00:00:00

  • Amyloidosis.

    abstract：:Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are derived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis i...

    journal_title：Histopathology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2559.1994.tb00001.x

    authors： Tan SY,Pepys MB

    更新日期：1994-11-01 00:00:00

  • Keratin 10-positive orthokeratotic dysplasia: a new leucoplakia-type precancerous entity of the oral mucosa.

    abstract：AIMS:We investigated a group of oral mucosal lesions with characteristic hyperorthokeratotic foci, which we termed orthokeratotic dysplasia (OKD), to determine if it could be identified as a distinct histopathological entity. METHODS AND RESULTS:We screened 282 surgical specimens from 200 patients with oral leucoplaki...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2012.04283.x

    authors： Kobayashi T,Maruyama S,Abé T,Cheng J,Takagi R,Saito C,Saku T

    更新日期：2012-11-01 00:00:00

  • Renal vascular disease in diabetes mellitus.

    abstract：:Nephropathy remains a major cause of morbidity and mortality in diabetes mellitus and increasing numbers of patients require dialysis maintenance therapy. Diagnostic criteria of diabetic nephropathy are well established, but the relationship between the morphological changes of glomerular basement membrane thickening ...

    journal_title：Histopathology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2559.1988.tb01950.x

    authors： Morley AR

    更新日期：1988-04-01 00:00:00

  • Liquid-based cytological and immunohistochemical study of nasopharyngeal swab from persons under investigation for SARS-CoV-2 infection.

    abstract：INTRODUCTION:We describe cytologic and immunohistologic findings in virus transport medium on cases under investigation of SARS-CoV-2 infection. METHODS:Cytologic findings in cases under investigation of SARS-CoV-2 infection from one hundred consecutive nasopharyngeal swab were reviewed. Immunohistochemistry and SARSC...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.14257

    authors： Parada D,Peña KB,Gumà J,Guilarte C,Riu F

    更新日期：2020-09-24 00:00:00

  • Coexpression of hypoxia-inducible factor-1α and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients.

    abstract：AIMS:To study whether coexpression of the two hypoxia-related proteins hypoxia-inducible factor (HIF)-1α and glucose transporter (GLUT)-1 has prognostic relevance in oral squamous cell carcinomas (OSCCs). METHODS AND RESULTS:Eighty-two OSCC samples were analysed for expression levels of HIF-1α and GLUT-1 by immunohist...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2011.03806.x

    authors： Eckert AW,Lautner MH,Schütze A,Taubert H,Schubert J,Bilkenroth U

    更新日期：2011-06-01 00:00:00

  • Differences in genetic instability and cellular phenotype among Barrett's, cardiac, and gastric intestinal metaplasia in a Japanese population with Helicobacter pylori.

    abstract：AIMS:Intestinal metaplasia is considered to be a precursor lesion in both Barrett's and intestinal-type gastric cancer. The aim was to clarify the differences in molecular pathology between specialized intestinal metaplasia (SIM) in Barrett's oesophagus (BO), cardiac (CIM) and gastric intestinal metaplasia (GIM). METH...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2009.03370.x

    authors： Watari J,Moriichi K,Tanabe H,Sato R,Fujiya M,Miwa H,Das KM,Kohgo Y

    更新日期：2009-09-01 00:00:00

  • Interobserver variation in CD30 immunohistochemistry interpretation; consequences for patient selection for targeted treatment.

    abstract：AIMS:CD30 immunohistochemistry (IHC) in malignant lymphoma is used for selection of patients in clinical trials using brentuximab vedotin, an antibody drug-conjugate targeting the CD30 molecule. For reliable implementation in daily practice and meaningful selection of patients for clinical trials, information on techni...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.13647

    authors： Koens L,van de Ven PM,Hijmering NJ,Kersten MJ,Diepstra A,Chamuleau M,de Jong D

    更新日期：2018-09-01 00:00:00

  • Detecting metastatic prostate carcinoma in pelvic lymph nodes following neoadjuvant hormone therapy: the eyes have it!

    abstract：AIMS:Residual cancer morphology in radical prostatectomies (RPs) after neoadjuvant hormone therapy includes inconspicuous cytology, and treated tumour cells can be difficult to identify in lymph nodes. The aim of this study was to evaluate the role of immunohistochemistry (IHC) in identifying occult lymph node metastas...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.12739

    authors： Kehr E,Masry P,Lis R,Loda M,Taplin ME,Hirsch MS

    更新日期：2016-01-01 00:00:00

  • Spindle cell squamous carcinoma of the lung. Immunocytochemical and ultrastructural study of a case.

    abstract：:A case of squamous cell carcinoma of the lung showing extensive spindle transformation is presented. On light microscopy, the tumour showed sheets and fascicles of elongated fusiform cells resulting in a growth pattern which closely resembled a sarcoma. Immunocytochemistry using tissue-specific antibodies against inte...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.1987.tb01890.x

    authors： Suster S,Huszar M,Herczeg E

    更新日期：1987-08-01 00:00:00

  • Diffuse lung disease in infancy and childhood: expanding the chILD classification.

    abstract：AIMS:Diffuse parenchymal lung diseases (DPLD) in children comprise a wide spectrum of rare disorders. In 2007 the Children's Interstitial Lung Disease (chILD) Research Cooperative proposed a classification system for DPLD in children <2 years of age. The aims of our study were to determine the utility and reproducibili...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.12185

    authors： Rice A,Tran-Dang MA,Bush A,Nicholson AG

    更新日期：2013-12-01 00:00:00

  • Biliary intraductal tubule-forming neoplasm: a whole exome sequencing study of MUC5AC-positive and -negative cases.

    abstract：AIMS:Biliary intraductal tubular neoplasms that are non-mucinous and negative for mucin 5AC (MUC5AC) are called intraductal tubulopapillary neoplasms (ITPNs). Intraductal tubular neoplasms with mucinous cytoplasm and MUC5AC positivity also occur and their nature remains unclear, although some pathologists may classify ...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.14103

    authors： Akita M,Hong SM,Sung YN,Kim MJ,Ajiki T,Fukumoto T,Itoh T,Zen Y

    更新日期：2020-06-01 00:00:00

  • Detailed analysis of the T-cell lymphocytic infiltrate in penile lichen sclerosus: an immunohistochemical and molecular investigation.

    abstract：AIM:To determine the extent of clonal outgrowth in the lymphocytic tissue infiltrate of lichen sclerosus (LS). The presence of T cells with a monoclonally rearranged T-cell receptor gamma-gene (TCRgamma) has been described in up to 50% of biopsies of vulvar and penile LS. MATERIAL AND RESULTS:We analysed 33 foreskin s...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2006.02406.x

    authors： Regauer S,Beham-Schmid C

    更新日期：2006-05-01 00:00:00

  • Accelerating type-specific ovarian carcinoma research: Calculator for Ovarian Subtype Prediction (COSP) is a reliable high-throughput tool for case review.

    abstract：AIMS:The recent recognition that ovarian carcinoma is composed of five distinct disease entities has served to increase the value of accurate histotyping. Reliable identification of histotypes is essential for the success of studies testing novel therapies, as well as for biomarker discovery research. The aim of this s...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.12219

    authors： Kommoss S,Gilks CB,Kommoss F,Chow C,Hilpert F,du Bois A,Köbel M,Huntsman DG,Anglesio M,Kalloger SE,Pfisterer J

    更新日期：2013-11-01 00:00:00

  • Digital pathology is a practical alternative to on-site intraoperative frozen section diagnosis in thoracic surgery.

    abstract：AIMS:Telepathology uses digitised image transfer to allow off-site reporting of histopathology slides. This technology could facilitate the centralisation of pathology services, which may improve their quality and cost-effectiveness. The benefits may be most apparent in frozen section reporting, in which turnaround tim...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.13804

    authors： French JMR,Betney DT,Abah U,Bhatt N,Internullo E,Casali G,Batchelor TJP,West DG

    更新日期：2019-05-01 00:00:00

  • Tumoral calcinosis: a clinicopathological study of 111 cases with emphasis on the earliest changes.

    abstract：AIMS:To study the pathogenesis of tumoral calcinosis (TC), we investigated 111 cases registered in Zaire over 30 years. METHODS AND RESULTS:The patients were 108 black Africans and three Caucasians between 3 and 74 years of age (mean, 37.7; median, 39). The gender was known in 33 males and 46 females; in 79 the gender...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1046/j.1365-2559.1997.6050831.x

    authors： Pakasa NM,Kalengayi RM

    更新日期：1997-07-01 00:00:00

  • Tenascin-C in primary malignant melanoma of the skin.

    abstract：AIMS:To investigate the expression and the prognostic role of glycoprotein Tenascin-C (Tn-C) in primary melanoma of the skin. METHODS AND RESULTS:The immunohistochemical expression of Tn-C was studied in 98 primary melanomas and related to inflammation, invasion, and patient outcome. Patients were followed up for dise...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2004.01976.x

    authors： Ilmonen S,Jahkola T,Turunen JP,Muhonen T,Asko-Seljavaara S

    更新日期：2004-10-01 00:00:00

  • Prognostic significance of proliferating cell nuclear antigen (PCNA) expression in gliomas.

    abstract：:The relationship between proliferating cell nuclear antigen (PCNA) expression and various clinicopathological indices (age, sex, tumour location, histological type and grade and treatment) and post-operative survival were studied in patients with central nervous system gliomas using univariate and multivariate analysi...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.1994.tb01353.x

    authors： Korkolopoulou P,Christodoulou P,Lekka-Katsouli I,Kouzelis K,Papanikolaou A,Panayotides I,Mariatos P,Thomas-Tsagli E,Crocker J

    更新日期：1994-10-01 00:00:00

  • Dataset for reporting of carcinoma of the urethra (in urethrectomy specimens): recommendations from the International Collaboration on Cancer Reporting (ICCR).

    abstract：:The International Collaboration on Cancer Reporting (ICCR) is a not-for-profit organisation sponsored by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Association of Pathologists in association with the Canadian Partnership Against Cancer, ...

    journal_title：Histopathology

    pub_type： 杂志文章,评审

    doi：10.1111/his.13877

    authors： Shanks JH,Srigley JR,Brimo F,Comperat E,Delahunt B,Koch M,Lopez-Beltran A,Reuter VE,Samaratunga H,Tsuzuki T,van der Kwast T,Varma M,Grignon D

    更新日期：2019-10-01 00:00:00

  • Cyclin A1 expression predicts progression in pT1 urothelial carcinoma of bladder: a tissue microarray study of 149 patients treated by transurethral resection.

    abstract：AIMS:To evaluate the immunoexpression of cyclin A1 in pT1 urothelial carcinomas of the bladder (UC) from a cohort of patients treated by transurethral resection of the bladder (TURB), to determine its value in predicting tumour recurrence, tumour progression, or systemic metastases. METHODS AND RESULTS:Five tissue mic...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.12499

    authors： Munari E,Chaux A,Maldonado L,Compérat E,Varinot J,Bivalacqua TJ,Hoque MO,Netto GJ

    更新日期：2015-01-01 00:00:00

  • Osteogenic differentiation in dedifferentiated liposarcoma: a study of 36 cases in comparison to the cases without ossification.

    abstract：AIMS:Ossification is found occasionally in dedifferentiated liposarcoma (DDLPS). The aims of this study were to elucidate whether the formed bone tissue is usually produced by tumour cells or by reactive non-neoplastic cells, and to reveal the clinicopathological characteristics of DDLPS with ossification. METHODS AND...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.13421

    authors： Yamashita K,Kohashi K,Yamada Y,Ishii T,Nishida Y,Urakawa H,Ito I,Takahashi M,Inoue T,Ito M,Ohara Y,Oda Y,Toyokuni S

    更新日期：2018-04-01 00:00:00

  • Pathological prognostic factors in locally advanced rectal carcinoma after neoadjuvant radiochemotherapy: analysis of 113 cases.

    abstract：AIMS:Neoadjuvant radiochemotherapy (RCT) followed by surgical resection is the treatment for locally advanced mid-rectal or low rectal cancer. The aim of this study was to evaluate postoperative histological prognostic factors in a series of surgical specimens after neoadjuvant RCT. METHODS AND RESULTS:One hundred and...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.12432

    authors： Sannier A,Lefèvre JH,Panis Y,Cazals-Hatem D,Bedossa P,Guedj N

    更新日期：2014-11-01 00:00:00

  • Intratumoral CD103-positive tumour-infiltrating lymphocytes are associated with favourable prognosis in patients with triple-negative breast cancer.

    abstract：AIMS:Cluster of differentiation 103 (CD103), a marker of tissue resident memory T cells, is expressed on subsets of CD8+ T lymphocytes. We investigated the prognostic significance of CD103+ intra-epithelial tumour-infiltrating lymphocytes (iTILs) in invasive breast cancer (IBC). METHODS AND RESULTS:Immunohistochemistr...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/his.14126

    authors： Park MH,Kwon SY,Choi JE,Gong G,Bae YK

    更新日期：2020-10-01 00:00:00

  • Nodular intra-abdominal panniculitis: an accompaniment of colorectal carcinoma and diverticular disease.

    abstract：:Intra-abdominal panniculitis is a tumour-like inflammatory condition of adipose tissue. The aetiology and pathogenesis of the disease is unknown, but a number of associated diseases have been recorded. It has been customary to deal with only primary cases in the literature. This study was undertaken in order to descri...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1046/j.1365-2559.1996.d01-486.x

    authors： Bak M

    更新日期：1996-07-01 00:00:00

  • Postchemotherapy changes in testicular germ cell tumours: biology and morphology.

    abstract：:Advances in modern chemotherapy and targeted treatments have resulted in lengthened survival in a variety of tumour types in the last decade. Increasingly in the 21st century, postchemotherapy resections are considered as a possible mode of treatment. Due to their exquisite chemosensitivity, resection of postchemother...

    journal_title：Histopathology

    pub_type： 杂志文章,评审

    doi：10.1111/his.13078

    authors： Berney DM,Lu YJ,Shamash J,Idrees M

    更新日期：2017-01-01 00:00:00

  • Differential expression of c-Met, its ligand HGF/SF and HER2/neu in DCIS and adjacent normal breast tissue.

    abstract：AIMS:Tyrosine kinase receptors Her2/neu and c-Met play an important role in breast cancer development and progression. Our aim was to determine the expression of c-Met, its ligand hepatocyte growth factor/scatter factor (HGF/SF) and Her2/neu in ductal carcinoma in situ (DCIS) lesions of the breast (n = 39) by two diffe...

    journal_title：Histopathology

    pub_type： 杂志文章

    doi：10.1111/j.1365-2559.2007.02732.x

    authors： Lindemann K,Resau J,Nährig J,Kort E,Leeser B,Annecke K,Welk A,Schäfer J,Vande Woude GF,Lengyel E,Harbeck N

    更新日期：2007-07-01 00:00:00