Nephroblastoma with fibroadenomatous-like structures.

abstract：AIMS:To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC). METHODS AND RESULTS:This study consisted of 25 patients with PSC and bile duct neoplasia [16 with cholangiocarcinoma and nine with biliary intra-epithelial ...

journal_title：Histopathology

authors： Zen Y,Quaglia A,Heaton N,Rela M,Portmann B

更新日期：2011-12-01 00:00:00

abstract：:In an ultrastructural study of oral lesions in lichen planus, it was found that some plasma cells have an associated lamina densa. Subsequently, similar appearances have been found in pemphigus vulgaris, in the inflammatory cell infiltrates in dental granulomas and cysts and in a patient with Ehlers-Danlos syndrome. T...

journal_title：Histopathology

authors： El-Labban NG

更新日期：1979-07-01 00:00:00

abstract：AIMS:Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in endometrial carcinomas and its pr...

journal_title：Histopathology

authors： Catasus L,Pons C,Muñoz J,Espinosa I,Prat J

更新日期：2013-03-01 00:00:00

abstract：:The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cel...

journal_title：Histopathology

authors： El-Labban NG,Lee KW

更新日期：1983-11-01 00:00:00

abstract：AIMS:To investigate whether Glia maturation factor-beta (GMFB) is expressed in thymomas and is associated with T-cell development. METHODS AND RESULTS:We investigated the expression of GMFB by immunohistochemistry in 86 cases of thymoma classified into five type A, 35 type AB, 11 type B1, 26 type B2, and nine type B3 ...

journal_title：Histopathology

authors： Yamazaki H,Tateyama H,Asai K,Fukai I,Fujii Y,Tada T,Eimoto T

更新日期：2005-09-01 00:00:00

abstract：AIM:To assess whether the distribution of the recently described proapoptotic ligand, tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), and the apoptosis effector, caspase-3 alters with the degree of inflammation and fibrosis present in liver biopsy specimens from patients with chronic hepatitis C virus...

journal_title：Histopathology

authors： Piekarska A,Kubiak R,Omulecka A,Szymczak W,Piekarski J

更新日期：2007-11-01 00:00:00

abstract：AIMS:Progressive changes have been reported in lymph nodes in HIV infection, but few accounts describe altered splenic histology at different stages of the disease. Investigation of splenic changes accompanying the progressive CD4+ T-cell depletion that occurs in HIV infection could shed light on normal immunological i...

journal_title：Histopathology

authors： Wilkins BS,Davis Z,Lucas SB,Delsol G,Jones DB

更新日期：2003-02-01 00:00:00

abstract：AIMS:Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). Oxaliplatin-associated liver toxicity has been reported and can affect clinical practice, but studies on its prevalence and a full pathological description are lacking....

journal_title：Histopathology

authors： Rubbia-Brandt L,Lauwers GY,Wang H,Majno PE,Tanabe K,Zhu AX,Brezault C,Soubrane O,Abdalla EK,Vauthey JN,Mentha G,Terris B

更新日期：2010-03-01 00:00:00

abstract：AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...

journal_title：Histopathology

authors： De Cecco L,Gariboldi M,Reid JF,Lagonigro MS,Tamborini E,Albertini V,Staurengo S,Pilotti S,Pierotti MA

更新日期：2005-03-01 00:00:00

abstract：AIMS:To evaluate the independent prognostic value of apoptotic versus proliferative fractions in a series of 92 patients with non-Hodgkin's lymphomas (NHL). METHODS AND RESULTS:Apoptotic fractions were quantified by use of the TdT (terminal deoxynucleotidyl-transferase)-mediated in-situ end-labelling technique (TUNEL)...

journal_title：Histopathology

authors： Korkolopoulou P,Angelopoulou MK,Kontopidou F,Tsenga A,Patsouris E,Thomas-Tsagli E,Kittas C,Pangalis GA

更新日期：1998-09-01 00:00:00

abstract：AIMS:The differential diagnosis of benign hepatic lesions and well-differentiated hepatocellular carcinomas can be a challenge, especially in small biopsy specimens. Recently, novel proteins expressed by the neovasculature in hepatocellular carcinoma (HCC) have been identified. The aim of this study was to compare the ...

journal_title：Histopathology

authors： Heukamp LC,Fischer HP,Schirmacher P,Chen X,Breuhahn K,Nicolay C,Büttner R,Gütgemann I

更新日期：2006-09-01 00:00:00

abstract：AIMS:p53 immunostaining in Barrett's oesophagus (BO) has been shown to be predictive of progression, but data regarding its generalizability to routine practice are lacking. This study compared the reliability of p53 and dysplasia interpretation and grading. METHODS AND RESULTS:Seventy-two cases encompassing the full ...

journal_title：Histopathology

authors： Kaye PV,Ilyas M,Soomro I,Haider SA,Atwal G,Menon S,Gill S,Richards C,Harrison R,West K,Ragunath K

更新日期：2016-09-01 00:00:00

abstract：AIMS:Trichoblastic carcinomas (malignant trichoblastomas) are rare and poorly documented neoplasms characterized by malignant transformation of a pre-existing benign trichoblastoma and subdivided histologically into low- and high-grade tumours. While morphologically low-grade trichoblastic carcinomas show an indolent b...

journal_title：Histopathology

authors： Mehta A,Davey J,Wiedemeyer K,Brenn T

更新日期：2021-01-03 00:00:00

abstract：AIMS:Immune check-point inhibitors are known to cause immune-mediated adverse liver injury, but our knowledge is mainly based on cases treated with ipilimumab or nivolumab. METHODS AND RESULTS:Clinicopathological features of 10 patients with hepatobiliary adverse reactions caused by second-generation drugs, pembrolizu...

journal_title：Histopathology

authors： Zen Y,Chen YY,Jeng YM,Tsai HW,Yeh MM

更新日期：2020-02-01 00:00:00

abstract：:S-100 positive epidermal dendritic cells were counted in skin biopsies from 48 Kveim tests and four known foreign-body reactions. Counts in histologically positive Kveim biopsies (mean 11.3 per 200 basal cells) were significantly higher than in either negative biopsies (5.1; P less than 0.001) or foreign-body reaction...

journal_title：Histopathology

authors： Shaw PA,Fletcher A

更新日期：1991-02-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：AIMS:To investigate the expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors and decoy receptors, including osteoprotegerin (OPG) in infantile haemangioma (IH). METHODS AND RESULTS:Immunostaining, Western blotting and quantitative reverse transcription-polymerase chain react...

journal_title：Histopathology

authors： Vishvanath A,Itinteang T,Tan ST,Day DJ

更新日期：2011-09-01 00:00:00

abstract：:Nephropathy remains a major cause of morbidity and mortality in diabetes mellitus and increasing numbers of patients require dialysis maintenance therapy. Diagnostic criteria of diabetic nephropathy are well established, but the relationship between the morphological changes of glomerular basement membrane thickening ...

journal_title：Histopathology

authors： Morley AR

更新日期：1988-04-01 00:00:00

abstract：AIMS:This study has compared the tissue expression of the p53 tumour suppressor protein and DNA repair proteins APE1, hMSH2 and ERCC1 in normal, dysplastic and malignant lip epithelium. METHODS AND RESULTS:Morphological analysis and immunohistochemistry were performed on archived specimens of normal lip mucosa (n=15),...

journal_title：Histopathology

authors： Souza LR,Fonseca-Silva T,Pereira CS,Santos EP,Lima LC,Carvalho HA,Gomez RS,Guimarães AL,De Paula AM

更新日期：2011-02-01 00:00:00

abstract：AIMS:Intestinal metaplasia is considered to be a precursor lesion in both Barrett's and intestinal-type gastric cancer. The aim was to clarify the differences in molecular pathology between specialized intestinal metaplasia (SIM) in Barrett's oesophagus (BO), cardiac (CIM) and gastric intestinal metaplasia (GIM). METH...

journal_title：Histopathology

authors： Watari J,Moriichi K,Tanabe H,Sato R,Fujiya M,Miwa H,Das KM,Kohgo Y

更新日期：2009-09-01 00:00:00

abstract：AIMS:The study was undertaken to demonstrate wild-type p53 in normal paraffin-embedded tissues using two widely used antibodies, DO7 and 1801 and two different antigen retrieval buffer systems. METHODS AND RESULTS:Formalin-fixed paraffin-embedded normal tissue samples were obtained from the archives of the John Radcli...

journal_title：Histopathology

authors： Pillai G,Roberts H,Gatter K,Pezzella F

更新日期：2003-01-01 00:00:00

abstract：AIMS:The B7 family check-point molecules are potential therapeutic targets in cancer immunotherapy. However, their expression status in human gestational trophoblastic neoplasia (GTN) remains unknown. We investigated the expression profiles of the B7 family check-point proteins PD-L1, PD-L2, B7-H3, B7-H4, VISTA and B7-...

journal_title：Histopathology

authors： Zong L,Zhang M,Wang W,Wan X,Yang J,Xiang Y

更新日期：2019-09-01 00:00:00

abstract：AIMS:Secretory carcinoma (SC) is a rare histological type of breast cancer, and ETV6-NTRK3 gene fusion is highly specific to it. The differential diagnoses of SC include acinic cell carcinoma (ACCA) and cystic hypersecretory carcinoma (CHC), as well as invasive ductal carcinoma (IDC). For patients with these rare but d...

journal_title：Histopathology

authors： Osako T,Takeuchi K,Horii R,Iwase T,Akiyama F

更新日期：2013-10-01 00:00:00

abstract：AIMS:The current WHO classification of thymic epithelial neoplasms describes type A and type AB thymomas as behaving 'like benign neoplasms'. However, recent published data suggest that rare cases may show more aggressive behaviour. The aim of this study was to assess the frequency of atypical cases, and to determine w...

journal_title：Histopathology

authors： Green AC,Marx A,Ströbel P,Mason M,Lim E,Jordan S,Ladas G,Dusmet M,Rice A,Nicholson AG

更新日期：2015-05-01 00:00:00

abstract：:One hundred and two cases of poorly differentiated adenocarcinoma were obtained from 71 surgical and 31 biopsy specimens of the stomach. These tumours produced both intracellular and extracellular mucins, which were demonstrated to be neutral mucins, N-acetyl sialomucins, sulphomucins and O-acetyl sialomucins. The maj...

journal_title：Histopathology

authors： Huang CB,Li WC,Xu J,Zhang YC

更新日期：1988-05-01 00:00:00

abstract：AIMS:Sixty new cases of human dirofilariasis due to Dirofilaria repens, occurring in Italy between 1990 and 1999, are presented. This is the most extensive case study of this zoonosis reported worldwide by a single study group. The aim is to utilize this large experience to characterize the different histopathological ...

journal_title：Histopathology

authors： Pampiglione S,Rivasi F,Angeli G,Boldorini R,Incensati RM,Pastormerlo M,Pavesi M,Ramponi A

更新日期：2001-04-01 00:00:00

abstract：AIMS:In nodular sclerosing Hodgkin's disease (NSHD), the prognostic relevance of the histopathological grading in two subtypes NSI (low-grade) and NSII (high-grade) remains controversial. Analysis of follicular dendritic cells (FDC) may provide new prognostic parameters. METHODS AND RESULTS:Tumours from 59 patients wi...

journal_title：Histopathology

authors： Baur AS,Meugé-Moraw C,Michel G,Delacrétaz F

更新日期：1998-06-01 00:00:00

abstract：AIMS:Regional differences in proliferative activity are commonly seen within breast cancers, but little is known on the extent of intratumoral heterogeneity of Ki67 expression. Our aim was to study the intratumoral heterogeneity of Ki67 expression in early breast cancers and its association with clinicopathological fea...

journal_title：Histopathology

authors： Focke CM,Decker T,van Diest PJ

更新日期：2016-11-01 00:00:00

abstract：AIMS:Focal nodular hyperplasia-like lesions have rarely been described in cirrhotic livers. We describe five cases of such lesions. METHODS AND RESULTS:Between 1998 and 2001, 146 liver transplants were performed at the Royal Free Hospital for cirrhosis of the liver. Nodular lesions identified in the livers removed at ...

journal_title：Histopathology

authors： Quaglia A,Tibballs J,Grasso A,Prasad N,Nozza P,Davies SE,Burroughs AK,Watkinson A,Dhillon AP

更新日期：2003-01-01 00:00:00

abstract：:Calcitonin is a hypocalcaemia producing hormone and is secreted by C-cells of the thyroid. The current study was undertaken on a hypothesis that C-cell hyperplasia may develop in the secondary hyperparathyroidism of chronic renal failure in response to sustained hypercalcaemia. With an immunoperoxidase staining method...

journal_title：Histopathology

authors： Tomita T,Millard DM

更新日期：1992-11-01 00:00:00