p53 expression in normal paraffin-embedded tissue using different antibodies and antigen retrieval buffer systems.

abstract：AIMS:Eosinophilic oesophagitis (EoE) is a chronic inflammatory disease characterised clinically by symptoms of oesophageal dysfunction and histopathologically by a prominent eosinophilic inflammation. Despite eosinophils having a histologically predominant position, their role in the immunopathogenesis of the disease i...

journal_title：Histopathology

authors： Strasser DS,Seger S,Bussmann C,Pierlot GM,Groenen PMA,Stalder AK,Straumann A

更新日期：2018-09-01 00:00:00

abstract：:The recognition of recurrent genetic alterations in specific tumour types has provided the basis for the reclassification of certain soft tissue neoplasms, and molecular analysis of patient material has the potential to provide both diagnostic and prognostic information. In this review, we evaluate the role of molecul...

journal_title：Histopathology

authors： Pfeifer JD,Hill DA,O'Sullivan MJ,Dehner LP

更新日期：2000-12-01 00:00:00

abstract：:Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are derived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis i...

journal_title：Histopathology

authors： Tan SY,Pepys MB

更新日期：1994-11-01 00:00:00

abstract：:There are many significant differences, but also considerable overlap between the quantitative histopathological features of mild and marked atypical endometrial hyperplasias and well and moderately differentiated carcinomas, thus preventing its application to individual patient care. To try to overcome this problem, ...

journal_title：Histopathology

authors： Baak JP,Kurver PH,Overdiep SH,Delemarre JF,Boon ME,Lindeman J,Diegenbach PC

更新日期：1981-11-01 00:00:00

abstract：AIMS:To investigate the expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors and decoy receptors, including osteoprotegerin (OPG) in infantile haemangioma (IH). METHODS AND RESULTS:Immunostaining, Western blotting and quantitative reverse transcription-polymerase chain react...

journal_title：Histopathology

authors： Vishvanath A,Itinteang T,Tan ST,Day DJ

更新日期：2011-09-01 00:00:00

abstract：AIMS:Tumour-infiltrating lymphocytes (TILs) are an important component of the immune response to cancer and have a prognostic value in breast cancer. Although several studies have investigated the role of T lymphocytes in breast cancer, the role of B lymphocytes (TIL-Bs) in ductal carcinoma in situ (DCIS) remains uncer...

journal_title：Histopathology

authors： Miligy I,Mohan P,Gaber A,Aleskandarany MA,Nolan CC,Diez-Rodriguez M,Mukherjee A,Chapman C,Ellis IO,Green AR,Rakha EA

更新日期：2017-08-01 00:00:00

abstract：AIMS:Follicular lymphoma (FL) in situ is defined as strongly bcl-2-positive B cells in germinal centres of morphologically inconspicuous lymph nodes. The prevalence and biological and clinical significance of this lesion are still not clear. Therefore we aimed at the detection of the prevalence of this phenomenon in an...

journal_title：Histopathology

authors： Henopp T,Quintanilla-Martínez L,Fend F,Adam P

更新日期：2011-07-01 00:00:00

abstract：AIMS:Telomerase is reactivated in most cancers and there is accumulating evidence that this is a driver event in malignant melanoma (MM). Thus, our aim was to evaluate if in-situ hybridization (ISH)-based quantification of telomerase RNA (hTR) could be used to distinguish MM from naevi, and if there was a correlation w...

journal_title：Histopathology

authors： Vagner J,Steiniche T,Stougaard M

更新日期：2015-04-01 00:00:00

abstract：AIMS:Although many immunohistochemical (IHC) cancer biomarkers have been identified, very few have translated into routine clinical practice, primarily because of technical and observational inconsistencies between studies. However, despite the obvious need to address such variability, very few studies have done so. M...

journal_title：Histopathology

authors： Lawrie CH,Ballabio E,Soilleux E,Sington J,Hatton CS,Dirnhofer S,Tzankov A

更新日期：2012-07-01 00:00:00

abstract：:Review of the histological sections of the tumours of 889 patients from the files of the SIOP Nephroblastoma trials and studies has revealed 23 cases with a distinctive growth pattern. Due to the similarity of the histological structures with the architecture of adenofibroma (fibroadenoma) of the ovary we have called ...

journal_title：Histopathology

authors： Delemarre JF,Sandstedt B,Tournade MF

更新日期：1984-01-01 00:00:00

abstract：AIMS:To assess KIT receptor tyrosine kinase and stem cell factor (SCF, KIT ligand) expression in tumour microvessel endothelial cells. METHODS AND RESULTS:KIT and SCF expression were studied in 248 human tumours consisting of 15 different histological types using immunohistochemistry and in situ hybridization for KIT ...

journal_title：Histopathology

authors： Sihto H,Tynninen O,Halonen M,Puputti M,Karjalainen-Lindsberg ML,Kukko H,Joensuu H

更新日期：2009-11-01 00:00:00

abstract：:Adenomatous hyperplasia, defined as a sizable parenchymal nodule in cirrhosis, was examined morphologically. Ninety-seven nodules of adenomatous hyperplasia were obtained from 47 cirrhotic livers and were divided into 'ordinary' (44 nodules) and 'atypical' (53 nodules) types. The former consisted of hepatocytes simila...

journal_title：Histopathology

authors： Nakanuma Y,Terada T,Terasaki S,Ueda K,Nonomura A,Kawahara E,Matsui O

更新日期：1990-07-01 00:00:00

abstract：AIMS:To evaluate whether a comprehensive histological evaluation of reticulin fibrosis, collagen deposition and osteosclerosis in bone marrow trephine biopsies (BMBs) of primary myelofibrosis (PMF) patients may have prognostic implications. METHODS AND RESULTS:Reticulin fibrosis, collagen deposition and osteosclerosis...

journal_title：Histopathology

authors： Gianelli U,Fiori S,Cattaneo D,Bossi A,Cortinovis I,Bonometti A,Ercoli G,Bucelli C,Orofino N,Bulfamante G,Iurlo A

更新日期：2017-12-01 00:00:00

abstract：:This study demonstrates the presence of three antigens in glandular metaplasia occurring in patients with cholecystitis and cholelithiasis: specifically carcinoembryonic antigen (CEA), large intestinal mucin antigen (LIMA) and small intestinal mucin antigen (SIMA). These antigens could not be detected in normal gall b...

journal_title：Histopathology

authors： De Boer WG,Ma J,Rees JW,Nayman J

更新日期：1981-05-01 00:00:00

abstract：:We report a case of oesophageal carcinosarcoma with prominent rhabdomyoblastic differentiation. Immunohistochemically, the rhabdomyblasts were mainly reactive to vimentin, cytokeratin, desmin, muscle-specific actin, myosin, and myoglobin, and were surrounded by laminin and type IV collagen-positive basement membranes....

journal_title：Histopathology

authors： Guarino M,Reale D,Micoli G,Forloni B

更新日期：1993-05-01 00:00:00

abstract：AIMS:Several studies have demonstrated that Na(+) /H(+) exchanger regulatory factor 1 (NHERF1) protein, which is overexpressed and heterogeneously distributed in different stages of breast cancer, could be used as a tumour marker for prognosis in molecular detection strategies. We observed that tumour-infiltrated lymph...

journal_title：Histopathology

authors： Bellizzi A,Mangia A,Malfettone A,Cardone RA,Simone G,Reshkin SJ,Paradiso A

更新日期：2011-06-01 00:00:00

abstract：AIMS:To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC). METHODS AND RESULTS:This study consisted of 25 patients with PSC and bile duct neoplasia [16 with cholangiocarcinoma and nine with biliary intra-epithelial ...

journal_title：Histopathology

authors： Zen Y,Quaglia A,Heaton N,Rela M,Portmann B

更新日期：2011-12-01 00:00:00

abstract：AIMS:Here we report two cases of follicular lymphoma that transformed to CD30 positive diffuse large B cell lymphoma and review the literature on this topic. RESULTS:The first case represents an example of early transformation of conventional low-grade follicular lymphoma to CD30-positive large B cell lymphoma. Immuno...

journal_title：Histopathology

authors： Montes-Moreno S,Climent F,González de Villambrosía S,González Barca EM,Batlle A,Insunza A,Pané-Foix M,Colorado M,Martin-Sánchez G,Espiga CR,Conde E,Piris MA

更新日期：2015-12-01 00:00:00

abstract：AIMS:Colorectal carcinoma (CRC) with micropapillary (MP) features has only been described recently and is still being characterized. METHODS AND RESULTS:We reviewed the clinicopathological and molecular features of 42 CRC with MP features. Twenty-nine cases were also evaluated for immunohistochemical evidence of epith...

journal_title：Histopathology

authors： Gonzalez RS,Huh WJ,Cates JM,Washington K,Beauchamp RD,Coffey RJ,Shi C

更新日期：2017-01-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...

journal_title：Histopathology

authors： Farrell K,Jarrett RF

更新日期：2011-01-01 00:00:00

abstract：:An ovarian and rectal carcinoid within the same person is described. The ovarian carcinoid is non-argentaffinic with typical regular granules. The rectal tumour consists of two types of APUD cells, some argentaffinic and diazo-positive, whilst others are non-argyrophilic. These features are mirrored ultrastructurally,...

journal_title：Histopathology

authors： Williams RM

更新日期：1979-01-01 00:00:00

abstract：:Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, incl...

journal_title：Histopathology

authors： Johnston PW,Fioratou E,Flin R

更新日期：2011-09-01 00:00:00

abstract：AIMS:Although delayed hypopituitarism is a common complication of conventional radiotherapy of sellar tumours, histological changes that may account for it have been rarely reported. To elucidate the changes, hypofunctional pituitary glands following irradiation were studied. METHODS AND RESULTS:Two pituitary glands o...

journal_title：Histopathology

authors： Nishioka H,Ito H,Haraoka J,Hirano A

更新日期：2001-06-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:Pseudosarcomatous myofibroblastic proliferations (PSMPs) of the urinary bladder are diagnostically challenging. Diagnostic difficulties are mainly due to frequent cytokeratin expression, variable ALK expression and worrisome morphological features suggestive of malignancy. Conversely, sarcomatoid urothelial carcin...

journal_title：Histopathology

authors： Bertz S,Stöhr R,Gaisa NT,Wullich B,Hartmann A,Agaimy A

更新日期：2020-12-01 00:00:00

abstract：AIMS:We investigated a group of oral mucosal lesions with characteristic hyperorthokeratotic foci, which we termed orthokeratotic dysplasia (OKD), to determine if it could be identified as a distinct histopathological entity. METHODS AND RESULTS:We screened 282 surgical specimens from 200 patients with oral leucoplaki...

journal_title：Histopathology

authors： Kobayashi T,Maruyama S,Abé T,Cheng J,Takagi R,Saito C,Saku T

更新日期：2012-11-01 00:00:00

abstract：:The paper reports a re-evaluation--based on the Kiel classification for non-Hodgkin lymphomas--of a group of cases initially diagnosed as undifferentiated small cell carcinomas or primary lymphomas of the thyroid. Twelve such cases were found among the 155 cases of primary malignant tumours of the thyroid recorded at ...

journal_title：Histopathology

authors： Heimann R,Vannineuse A,De Sloover C,Dor P

更新日期：1978-05-01 00:00:00

abstract：AIMS:The available evidence indicates that most non-uterine high-grade serous carcinomas (HGSCs) arise from the fallopian tube (FT), but approaches to primary site assignment have not evolved to reflect this. The aim of this study was to assess the application of recently proposed criteria for site assignment. METHODS...

journal_title：Histopathology

authors： Singh N,Gilks CB,Wilkinson N,McCluggage WG

更新日期：2015-09-01 00:00:00

abstract：AIMS:Tissue microarray (TMA) is an efficient technique for analysis of molecular markers. Prospectively collected samples have been reported to give excellent concordance between TMA data and corresponding whole-sections. The aim was to evaluate the usefulness of TMA in a population-based cohort of 213 women with ducta...

journal_title：Histopathology

authors： Wärnberg F,Amini RM,Goldman M,Jirström K

更新日期：2008-12-01 00:00:00

abstract：:Aberrant crypt foci (ACF) have been identified in the methylene-blue stained mucosa of the human colon. Some lines of evidence suggest that ACF may be precursors of colon cancer. The objective of the present study was to establish morphological criteria able to define and classify ACF in histological sections. Twenty-...

journal_title：Histopathology

authors： Di Gregorio C,Losi L,Fante R,Modica S,Ghidoni M,Pedroni M,Tamassia MG,Gafà L,Ponz de Leon M,Roncucci L

更新日期：1997-04-01 00:00:00