Abstract:
:An ovarian and rectal carcinoid within the same person is described. The ovarian carcinoid is non-argentaffinic with typical regular granules. The rectal tumour consists of two types of APUD cells, some argentaffinic and diazo-positive, whilst others are non-argyrophilic. These features are mirrored ultrastructurally, some cells containing the large pleomorphic argentaffinic granules while others have smaller regular granules. In addition, focal aggregates of microfilaments were found in both tumour types. These findings are discussed in terms of the APUD concept. The similarities of the APUD tumour cells to D1 APUD cells of the duodenum is highlighted, and an alternative explanation for their derivation is proposed.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Williams RMdoi
10.1111/j.1365-2559.1979.tb02978.xsubject
Has Abstractpub_date
1979-01-01 00:00:00pages
19-30issue
1eissn
0309-0167issn
1365-2559journal_volume
3pub_type
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