Abstract:
:The stereological estimate of mean nuclear volume is an objective and reproducible method of measurement of nuclear size in terms of absolute volume. We have used this method to study carcinomas of the ampulla of Vater. Our study includes 21 cases--five papillary and 16 intestinal--all treated by the same surgical procedure. The volume-weighted mean nuclear volume (nuclear nu v) and the mean nuclear area were calculated. The mean volumes of nuclear nu v were significantly different (P less than 0.01) between the papillary and intestinal carcinomas, but no differences were found between normal mucosa and papillary carcinoma. The variance was significantly larger in the intestinal group than the papillary and normal groups. The nuclear nu v showed a significant association with survival, larger nuclear nu v (greater than 150 microns 3) being associated with a lower survival rate.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Artacho-Perula E,Roldan-Villalobos R,Lopez-Rubio F,Vaamonde-Lemos Rdoi
10.1111/j.1365-2559.1992.tb00382.xkeywords:
subject
Has Abstractpub_date
1992-09-01 00:00:00pages
241-8issue
3eissn
0309-0167issn
1365-2559journal_volume
21pub_type
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