Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entity.

abstract：AIMS:We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). METHODS AND RESULTS:A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial in...

journal_title：Histopathology

authors： Serrano R,Martínez MA,Andrés A,Morales JM,Samartin R

更新日期：1998-08-01 00:00:00

abstract：:A procedure for the simultaneous fixation and decalcification of bone biopsies is described. Mild acidic fixatives (such as Bouin's fluid) are effective decalcifying agents when made calcium-free by a continuous circulation through a column of anion-binding ion exchange resin. The procedure has been found relatively f...

journal_title：Histopathology

authors： Bussolati G

更新日期：1978-09-01 00:00:00

abstract：AIMS:There have been several cell kinetic studies of thymoma, but the effectiveness of using Ki67 antibody as a tool to measure proliferative activity in this tumour was rarely evaluated. We carried out an immuno-histochemical study using this antibody to assess the clinicopathological correlation and the prognostic si...

journal_title：Histopathology

authors： Pan CC,Ho DM,Chen WY,Huang CW,Chiang H

更新日期：1998-11-01 00:00:00

abstract：AIMS:To study immunohistochemically a group of 28 primary lung cancers which demonstrated histological features reminiscent of those characteristic of regression in malignant melanoma, to determine the phenotype of their immune cell infiltrates. METHODS AND RESULTS:Using a standard s-ABC immunoperoxidase method then q...

journal_title：Histopathology

authors： Kerr KM,Johnson SK,King G,Kennedy MM,Weir J,Jeffrey R

更新日期：1998-07-01 00:00:00

abstract：:A study was made of the cells forming the crescents in human crescentic glomerulonephritis. The investigation was performed using a panel of antibodies with immunoperoxidase techniques in formalin fixed, paraffin embedded renal biopsy material. Some of the cells of glomerular crescents were found to contain cytokerati...

journal_title：Histopathology

authors： Harrison DJ,MacDonald MK

更新日期：1986-09-01 00:00:00

abstract：AIMS:To evaluate the use of the Wilms' tumour gene (WT1) marker and histomorphological parameters as indicators of prognosis in malignant peritoneal mesothelioma (MPM). METHODS AND RESULTS:Histological samples of 31 MPM were stained immunohistochemically for the WT1 protein. The results were quantified by recording th...

journal_title：Histopathology

authors： Scattone A,Serio G,Marzullo A,Nazzaro P,Corsi F,Cocca MP,Mattoni M,Punzi A,Gentile M,Buonadonna AL,Pennella A

更新日期：2012-02-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:The clinical outcome of patients with locally advanced rectal cancer who undergo neoadjuvant chemoradiotherapy (CRT) is influenced by the tumour response to treatment, which is reflected by tumour regression grade and post-treatment (y) TNM stage. Little is known about the prognostic value of pretreatment histopat...

journal_title：Histopathology

authors： Reggiani Bonetti L,Lionti S,Domati F,Pagliani G,Mattioli E,Barresi V

更新日期：2017-09-01 00:00:00

abstract：AIMS:The aims of this study were to define whether diffuse cutaneous reticulohistiocytosis could be underpinned by somatic genetic alterations and represent a precursor of more aggressive forms of disease. METHODS AND RESULTS:A 59-year-old man with diffuse cutaneous reticulohistiocytosis experienced bone marrow locali...

journal_title：Histopathology

authors： Fusco N,Bonometti A,Augello C,Fabris S,Boiocchi L,Fiori S,Morotti D,Fracchiolla N,Berti E,Gianelli U

更新日期：2017-05-01 00:00:00

abstract：:A series of 104 biopsy cases with histopathological proof of amyloid, submitted to our department of pathology over the last 19 years, were re-examined. The survey investigated the medical indication for surgery, the origin and quality of the biopsy and the clinical information as documented on the request form for hi...

journal_title：Histopathology

authors： Röcken C,Schwotzer EB,Linke RP,Saeger W

更新日期：1996-10-01 00:00:00

abstract：:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial bi...

journal_title：Histopathology

authors： Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

更新日期：1991-03-01 00:00:00

abstract：:A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

journal_title：Histopathology

authors： Huang DP,Ng HK,Ho YH,Chan KM

更新日期：1988-11-01 00:00:00

abstract：AIM:To evaluate the intraobserver and interobserver reproducibility of the HER2 in-situ hybridization (ISH) test in breast cancer by measuring the impact of counting different numbers of invasive cancer cells. METHODS AND RESULTS:A cohort of 101 primary invasive breast cancer cases were evaluated for HER2 gene amplifi...

journal_title：Histopathology

authors： Polónia A,Eloy C,Pinto J,Braga AC,Oliveira G,Schmitt F

更新日期：2017-08-01 00:00:00

abstract：:One hundred and eighty-seven operable lung tumours were immunostained with the monoclonal antibody Ki-67 and divided into groups of high, moderate or low proliferation. Patients have been followed clinically for up to 7 years to ascertain whether this immunocytochemical measurement reflected tumour behaviour in terms ...

journal_title：Histopathology

authors： Tungekar MF,Gatter KC,Dunnill MS,Mason DY

更新日期：1991-12-01 00:00:00

abstract：:Hairy leukoplakia is a recently described oral mucosal condition seen in immunosuppressed individuals, usually in association with HIV infection, when it is thought to be a sign of decreasing immunocompetence. It probably results from reactivation of infection by Epstein-Barr virus (EBV) and usually presents as bilate...

journal_title：Histopathology

authors： Southam JC,Felix DH,Wray D,Cubie HA

更新日期：1991-07-01 00:00:00

abstract：:Formalin-fixed, paraffin-embedded material from 15 haemangioendotheliosarcomas and eight malignant haemangiopericytomas was stained with an immunohistochemical technique for the presence of factor VIII-related antigen (F VIII-RAg), actin, laminin and for reactivity with the lectin Ulex europaeus I (UEA-I). Haemangioen...

journal_title：Histopathology

authors： Hultberg BM,Daugaard S,Johansen HF,Mouridsen HT,Hou-Jensen K

更新日期：1988-04-01 00:00:00

abstract：:The CD30 antigen is a characteristic phenotypic feature of Sternberg-Reed and Hodgkin cells and is also found in a subset of large cell non-Hodgkin's lymphomas. The finding of CD30 positive cells in some centroblastic/centrocytic (cb/cc) follicular lymphomas prompted us to characterize the presence and distribution of...

journal_title：Histopathology

authors： Piris M,Gatter KC,Mason DY

更新日期：1991-01-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...

journal_title：Histopathology

authors： Farrell K,Jarrett RF

更新日期：2011-01-01 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a member of the lipocalin superfamily. Although its overexpression in various cancers has been reported, little is known about its expression and clinical significance in oral squamous cell carcinoma (OSCC). This study aimed to elucidate the clinical significanc...

journal_title：Histopathology

authors： Shinriki S,Jono H,Ueda M,Obayashi K,Nakamura T,Ota K,Ota T,Sueyoshi T,Guo J,Hayashi M,Hiraki A,Nakayama H,Yamashita S,Shinohara M,Ando Y

更新日期：2014-02-01 00:00:00

abstract：AIMS:The cadherin-catenin complex is known to play a critical role in maintenance of cell adhesion. Additionally beta-catenin (beta-ct) can also take part in signal transduction and nuclear beta-ct expression could be correlated with poor prognosis in several malignancies. Since, in gastric cancer, this role of beta-ct...

journal_title：Histopathology

authors： Grabsch H,Takeno S,Noguchi T,Hommel G,Gabbert HE,Mueller W

更新日期：2001-08-01 00:00:00

abstract：:Two cases of atypical juvenile polyposis are described in males of 9 months and 25 years-of-age. The first was associated with congenital megacolon and presented as juvenile polyps with features suggesting mild dysplasia. In the second case six histological lesions are found: I hyperplastic polyps; 2 juvenile polyps; ...

journal_title：Histopathology

authors： Grigioni WF,Alampi G,Martinelli G,Piccaluga A

更新日期：1981-07-01 00:00:00

abstract：AIM:Alveolar capillary dysplasia (ACD) is a rare disorder, typically presenting with persistent pulmonary hypertension of the newborn. The aim was to characterise further the histological features of patients suspected of having ACD and to correlate histopathological features with outcome. METHODS AND RESULTS:Three pa...

journal_title：Histopathology

authors： Melly L,Sebire NJ,Malone M,Nicholson AG

更新日期：2008-10-01 00:00:00

abstract：AIMS:Fibroadenomas (FAs) and phyllodes tumours (PTs) are fibroepithelial tumours. Mutations in MED12 exon 2 have been reported in FAs. This study investigated the MED12 mutations in a spectrum of fibroepithelial tumours. METHODS AND RESULTS:Using direct sequencing, we analysed MED12 exon 2 mutations on 121 samples, in...

journal_title：Histopathology

authors： Lien HC,Huang CS,Yang YW,Jeng YM

更新日期：2016-02-01 00:00:00

abstract：AIMS:CDX2 is widely used as a sensitive and specific immunomarker for colorectal carcinoma (CRC), but neither its sensitivity nor its specificity is absolute. The aim of this study was to compare CDX1 and A33 with CDX2 as immunomarkers for CRC. METHODS AND RESULTS:As a pilot study, whole sections of 51 cases of liver ...

journal_title：Histopathology

authors： Wong NACS,Adamczyk LA,Evans S,Cullen J,Oniscu A,Oien KA

更新日期：2017-07-01 00:00:00

abstract：:Elastosis, a previously unreported feature, was found to be common in granular cell tumours. Twenty-four of 28 consecutive granular cell tumours were shown to display elastosis. The elastosis was found in three main sites: adventitial, interstitial and septal. Elastosis is statistically associated with the fibrosis pr...

journal_title：Histopathology

authors： McMahon JN,Rigby HS,Davies JD

更新日期：1990-01-01 00:00:00

abstract：:We reviewed 45 pulmonary B-cell non-Hodgkin's lymphomas to determine whether their morphology and immunohistochemical features were those of lymphomas arising from mucosa-associated lymphoid tissue (MALT), as described in other sites. The polymerase chain reaction was used to provide further information on clonality. ...

journal_title：Histopathology

authors： Nicholson AG,Wotherspoon AC,Diss TC,Butcher DN,Sheppard MN,Isaacson PG,Corrin B

更新日期：1995-05-01 00:00:00

abstract：AIMS:To investigate the protein expressions of breast cancer 1 (BRCA1) and 2 (BRCA2) in prostatectomy specimens of localized prostate cancer (PC) patients, along with their associations with cancer characteristics and prognosis. METHODS AND RESULTS:Immunohistochemistry for BRCA1 and BRCA2 was performed on tissue micro...

journal_title：Histopathology

authors： Kim SH,Park WS,Yun SI,Joo J,Joung JY,Seo HK,Chung J,Lee GK,Lee KH

更新日期：2016-04-01 00:00:00

abstract：AIMS:To assess the immunophenotypic changes associated with epithelial-mesenchymal transition (EMT) in endocervical adenocarcinoma, and correlate the findings with tumour morphology including growth pattern. METHODS AND RESULTS:Twenty-seven endocervical adenocarcinomas were studied using a panel of immunohistochemical...

journal_title：Histopathology

authors： Stewart CJ,Crook ML,Little L,Louwen K

更新日期：2011-04-01 00:00:00

abstract：:Tylosis is an autosomal dominant inherited defect of keratinization, associated in two Liverpool families with a high risk of developing oesophageal squamous carcinoma. In 29 individuals, followed by regular endoscopy and biopsy, we have noted several morphological abnormalities of the epithelium in this pre-cancerous...

journal_title：Histopathology

authors： Ashworth MT,Nash JR,Ellis A,Day DW

更新日期：1991-10-01 00:00:00

abstract：AIMS:Polymorphous low-grade adenocarcinoma (PLGA) is the second most common intra-oral salivary gland malignancy. The vast majority of PLGAs harbour a PRKD1 E710D hot-spot somatic mutation or somatic rearrangements of PRKD1, PRKD2 or PRKD3. Given the kinase domain homology among PRKD1, PRKD2 and PRKD3, we sought to def...

journal_title：Histopathology

authors： Piscuoglio S,Fusco N,Ng CK,Martelotto LG,da Cruz Paula A,Katabi N,Rubin BP,Skálová A,Weinreb I,Weigelt B,Reis-Filho JS

更新日期：2016-06-01 00:00:00