Correlation between invasive pattern and immunophenotypic alterations in endocervical adenocarcinoma.

abstract：AIMS:It is known that thyroid transcription factor-1 (TTF-1) is expressed in a small percentage of primary gynaecological adenocarcinomas. Following the observation of TTF-1 positivity in a number of endometrioid adenocarcinomas of the uterine corpus which behaved aggressively, we undertook immunohistochemical staining...

journal_title：Histopathology

authors： Ervine A,Leung S,Gilks CB,McCluggage WG

更新日期：2014-05-01 00:00:00

abstract：:Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

journal_title：Histopathology

authors： Thomas de Montpréville V,Dulmet EM

更新日期：1995-09-01 00:00:00

abstract：:A 76-year-old man with lymphoma involving cervical and mediastinal lymph nodes and abdomen was treated by radiotherapy and chemotherapy. He subsequently developed cytomegalovirus gastritis and gastric ulcers with a gastrocolic fistula and a jejuno-jejunal fistula, necessitating a partial gastrectomy. The pathogenesis ...

journal_title：Histopathology

authors： Aqel NM,Tanner P,Drury A,Francis ND,Henry K

更新日期：1991-02-01 00:00:00

abstract：:Review of the histological sections of the tumours of 889 patients from the files of the SIOP Nephroblastoma trials and studies has revealed 23 cases with a distinctive growth pattern. Due to the similarity of the histological structures with the architecture of adenofibroma (fibroadenoma) of the ovary we have called ...

journal_title：Histopathology

authors： Delemarre JF,Sandstedt B,Tournade MF

更新日期：1984-01-01 00:00:00

abstract：AIMS:Although many immunohistochemical (IHC) cancer biomarkers have been identified, very few have translated into routine clinical practice, primarily because of technical and observational inconsistencies between studies. However, despite the obvious need to address such variability, very few studies have done so. M...

journal_title：Histopathology

authors： Lawrie CH,Ballabio E,Soilleux E,Sington J,Hatton CS,Dirnhofer S,Tzankov A

更新日期：2012-07-01 00:00:00

abstract：AIMS:In order to develop efficient digital pathology workstations, we studied the navigation patterns of pathologists diagnosing whole-slide images. To gain a better understanding of these patterns, we built a conceptual model based on observations. We also determined whether or not new navigation patterns have emerged...

journal_title：Histopathology

authors： Molin J,Fjeld M,Mello-Thoms C,Lundström C

更新日期：2015-08-01 00:00:00

abstract：AIMS:Focal nodular hyperplasia-like lesions have rarely been described in cirrhotic livers. We describe five cases of such lesions. METHODS AND RESULTS:Between 1998 and 2001, 146 liver transplants were performed at the Royal Free Hospital for cirrhosis of the liver. Nodular lesions identified in the livers removed at ...

journal_title：Histopathology

authors： Quaglia A,Tibballs J,Grasso A,Prasad N,Nozza P,Davies SE,Burroughs AK,Watkinson A,Dhillon AP

更新日期：2003-01-01 00:00:00

abstract：AIMS:To identify histopathological and immunohistochemical findings that aid diagnosis of metastatic endometrial stromal sarcoma (ESS) in small biopsy specimens of the lung. METHODS AND RESULTS:We reviewed the histology of 46 lung nodules from 10 cases of pulmonary metastatic ESS. Biopsy sections were analysed by immu...

journal_title：Histopathology

authors： Park JY,Sung CO,Jang SJ,Song SY,Han JH,Kim KR

更新日期：2013-12-01 00:00:00

abstract：AIMS:To evaluate the immunoexpression of cyclin A1 in pT1 urothelial carcinomas of the bladder (UC) from a cohort of patients treated by transurethral resection of the bladder (TURB), to determine its value in predicting tumour recurrence, tumour progression, or systemic metastases. METHODS AND RESULTS:Five tissue mic...

journal_title：Histopathology

authors： Munari E,Chaux A,Maldonado L,Compérat E,Varinot J,Bivalacqua TJ,Hoque MO,Netto GJ

更新日期：2015-01-01 00:00:00

abstract：AIMS:Carbonic anhydrase VI (CA6) is present in serous acinar cells of human salivary glands. The aim of this study was to investigate the diagnostic utility of CA6 in differentiating acinic cell carcinoma (AciCC) from its morphological mimic mammary analogue secretory carcinoma (MASC) of the salivary gland. METHODS AN...

journal_title：Histopathology

authors： Hsieh MS,Jeng YM,Jhuang YL,Chou YH,Lin CY

更新日期：2016-04-01 00:00:00

abstract：AIMS:Biphenotypic sinonasal sarcoma (SNS) is a locally aggressive tumour that occurs in the sinonasal region. PAX3-MAML3 has recently been identified as a recurrent fusion gene event in this entity; however, a subset of tumours harbour alternative PAX3 rearrangement without the involvement of MAML3. In this study we so...

journal_title：Histopathology

authors： Fritchie KJ,Jin L,Wang X,Graham RP,Torbenson MS,Lewis JE,Rivera M,Garcia JJ,Schembri-Wismayer DJ,Westendorf JJ,Chou MM,Dong J,Oliveira AM

更新日期：2016-12-01 00:00:00

abstract：:A case is reported of nodular lymphocyte predominant Hodgkin's disease arising 13 years after the removal of a lymph node from the same site which showed marked progressive transformation of germinal centres. The morphological evidence for a histogenetic relationship between the two conditions is presented and discuss...

journal_title：Histopathology

authors： Crossley B,Heryet A,Gatter KC

更新日期：1987-06-01 00:00:00

abstract：AIMS:Atypical polypoid adenomyoma (APAM) is an uncommon uterine lesion composed of complex endometrioid glands with frequent squamous morular metaplasia and fibromuscular stroma. On endometrial curettage, biopsy, or polypectomy specimens, the admixture of endometrioid glands and smooth muscle raises the differential di...

journal_title：Histopathology

authors： Worrell HI,Sciallis AP,Skala SL

更新日期：2021-01-18 00:00:00

abstract：AIM:Alveolar capillary dysplasia (ACD) is a rare disorder, typically presenting with persistent pulmonary hypertension of the newborn. The aim was to characterise further the histological features of patients suspected of having ACD and to correlate histopathological features with outcome. METHODS AND RESULTS:Three pa...

journal_title：Histopathology

authors： Melly L,Sebire NJ,Malone M,Nicholson AG

更新日期：2008-10-01 00:00:00

abstract：:Eleven colloid cysts of the third ventricle were investigated by immunohistochemistry using 16 mono- and polyclonal antibodies. Colloid cyst epithelium, choroid plexus epithelium and ependyma showed different immunohistochemical profiles. In particular, antibodies to different cytokeratins and to transthyretin reveale...

journal_title：Histopathology

authors： Kuchelmeister K,Bergmann M

更新日期：1992-07-01 00:00:00

abstract：AIMS:We report the clinicopathological and immunohistochemical characteristics of 12 cases of a recently recognized entity, oncocytic papillary thyroid carcinoma (PC) with lymphoid stroma (Warthin-like tumour). METHODS AND RESULTS:The cases were retrieved from the surgical pathology files of our departments. There wer...

journal_title：Histopathology

authors： Ludvíková M,Ryska A,Korabecná M,Rydlová M,Michal M

更新日期：2001-07-01 00:00:00

abstract：AIMS:Pleomorphic lobular carcinoma (PLC) is an aggressive variant of invasive lobular carcinoma. The aim of this study was to redefine PLC in terms of molecular classification. METHODS AND RESULTS:Cases of PLC were selected between 1995 and 2010. Key clinicopathological features were recorded for most of the patients....

journal_title：Histopathology

authors： Monhollen L,Morrison C,Ademuyiwa FO,Chandrasekhar R,Khoury T

更新日期：2012-09-01 00:00:00

abstract：AIMS:To investigate redox-regulating enzymes that may have a special role in melanoma pathogenesis due to continuous exposure to microenvironment-produced and ultraviolet radiation-induced oxidative stress. METHODS AND RESULTS:We assessed immunohistochemically the expression of antioxidant enzymes peroxiredoxins (Prxs...

journal_title：Histopathology

authors： Hintsala HR,Soini Y,Haapasaari KM,Karihtala P

更新日期：2015-09-01 00:00:00

abstract：AIMS:The diagnosis of cutaneous γδ T-cell lymphoma (GDTCL) requires the identification of γδ chains of the T-cell receptor (TCR). Our aim in this study was, by using a new monoclonal antibody (mAb) against TCRδ, to evaluate TCRδ expression in formalin-fixed paraffin-embedded (FFPE) skin tissue from TCRγ+ cutaneous T-ce...

journal_title：Histopathology

authors： Pulitzer M,Geller S,Kumar E,Frosina D,Moskowitz A,Horwitz S,Myskowski P,Kheterpal M,Chan A,Dogan A,Jungbluth A

更新日期：2018-10-01 00:00:00

abstract：AIMS:Owing to their close embryological relationship, soft tissue perineurioma and meningioma may closely mimic each other, not only histologically but also by immunohistochemistry. We aimed to compare the frequency of perineurial marker expression in these two entities, and to determine whether somatostatin receptor 2...

journal_title：Histopathology

authors： Agaimy A,Buslei R,Coras R,Rubin BP,Mentzel T

更新日期：2014-07-01 00:00:00

abstract：AIMS:To assess the outcome of breast papillary lesions diagnosed by ultrasound-guided core needle biopsy (CB) or vacuum-assisted 'mammotome' biopsy (MT), the accuracy of these diagnoses, and whether it is justified not to undertake surgical excision of non-malignant papillary lesions so diagnosed. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Yamaguchi R,Tanaka M,Tse GM,Yamaguchi M,Terasaki H,Hirai Y,Nonaka Y,Morita M,Yokoyama T,Kanomata N,Naito Y,Akiba J,Yano H

更新日期：2015-03-01 00:00:00

abstract：:In an ultrastructural study of oral lesions in lichen planus, it was found that some plasma cells have an associated lamina densa. Subsequently, similar appearances have been found in pemphigus vulgaris, in the inflammatory cell infiltrates in dental granulomas and cysts and in a patient with Ehlers-Danlos syndrome. T...

journal_title：Histopathology

authors： El-Labban NG

更新日期：1979-07-01 00:00:00

abstract：AIMS:Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in endometrial carcinomas and its pr...

journal_title：Histopathology

authors： Catasus L,Pons C,Muñoz J,Espinosa I,Prat J

更新日期：2013-03-01 00:00:00

abstract：AIMS:We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). METHODS AND RESULTS:A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial in...

journal_title：Histopathology

authors： Serrano R,Martínez MA,Andrés A,Morales JM,Samartin R

更新日期：1998-08-01 00:00:00

abstract：:Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular pathology of thyroid tumours originating from follicular cells has greatly advanced in the past several years. Common molecular alterations, such as BRAF p.V600E, RAS point mutations, and fusion oncogenes (RET-PTC being the prototypical...

journal_title：Histopathology

authors： Acquaviva G,Visani M,Repaci A,Rhoden KJ,de Biase D,Pession A,Giovanni T

更新日期：2018-01-01 00:00:00

abstract：AIMS:Class III beta-tubulin (TUBB3) reduces microtubule stability and confers resistance to microtubule-stabilizing taxanes, including paclitaxel and docetaxel. Pancreatic ductal adenocarcinomas show limited responsiveness to taxanes, but little is known of the underlying mechanisms. The aim of this study was to examin...

journal_title：Histopathology

authors： Lee KM,Cao D,Itami A,Pour PM,Hruban RH,Maitra A,Ouellette MM

更新日期：2007-10-01 00:00:00

abstract：:The monoclonal antibody NCRC-11, which has epithelial membrane antigen (EMA)-like immunoreactivity, was used to identify intracytoplasmic lumina in a series of 105 adenocarcinomas from various sites and in 283 breast carcinomas; 55% of the non-breast carcinomas and all breast carcinomas except one of spindle cell type...

journal_title：Histopathology

authors： Quincey C,Raitt N,Bell J,Ellis IO

更新日期：1991-07-01 00:00:00

abstract：:Waldeyer ring lymphomas belong to a category of tumours which has not yet been fully defined. Their relation to mucosa-associated lymphoid tissue (MALT) and other extranodal lymphomas remains largely unknown. We performed a clinicopathological retrospective study of 79 patients, and compared them with a series of MALT...

journal_title：Histopathology

authors： Menárguez J,Mollejo M,Carrión R,Oliva H,Bellas C,Forteza J,Martin C,Ruiz-Marcellán C,Morente M,Romagosa V

更新日期：1994-01-01 00:00:00

abstract：:Cytokeratin antibodies have been widely used for the identification of trophoblast cells in the placental bed, following their invasion from the developing conceptus. Their identification centres upon the expression of cytokeratin in epithelial cells, from which trophoblast cells are derived. Our recent observations i...

journal_title：Histopathology

authors： Stiemer B,Graf R,Neudeck H,Hildebrandt R,Hopp H,Weitzel HK

更新日期：1995-11-01 00:00:00

abstract：AIMS:Residual cancer morphology in radical prostatectomies (RPs) after neoadjuvant hormone therapy includes inconspicuous cytology, and treated tumour cells can be difficult to identify in lymph nodes. The aim of this study was to evaluate the role of immunohistochemistry (IHC) in identifying occult lymph node metastas...

journal_title：Histopathology

authors： Kehr E,Masry P,Lis R,Loda M,Taplin ME,Hirsch MS

更新日期：2016-01-01 00:00:00