Intracytoplasmic lumina--a useful diagnostic feature of adenocarcinomas.

abstract：AIMS:To evaluate whether there is a correlation between the subcellular localization of maspin and the histological, molecular and biological features of pulmonary adenocarcinoma, particularly addressing the hypothesis that the tumour inhibitor properties of maspin may be linked to a nuclear, compared with a combined n...

journal_title：Histopathology

authors： Frey A,Soubani AO,Adam AK,Sheng S,Pass HI,Lonardo F

更新日期：2009-04-01 00:00:00

abstract：:A review of 76 endomyocardial biopsies and 54 autopsies of patients with dilated cardiomyopathy (DCM) revealed features of hypertrophy and degenerative changes associated with long-standing hypertrophy. Long-term survivors had significantly heavier heart weights. Short-term survivors had heavier than normal right vent...

journal_title：Histopathology

authors： Rose AG,Beck W

更新日期：1985-04-01 00:00:00

abstract：AIMS:To evaluate the immunohistochemistry using an anti-mitochondria antibody in the investigation of various oncocytic lesions of the salivary glands. METHODS AND RESULTS:Ten cases of adenolymphoma (Warthin's tumour) and one case each of benign oncocytoma and oncocytic carcinoma of the salivary glands were examined. ...

journal_title：Histopathology

authors： Shintaku M,Honda T

更新日期：1997-11-01 00:00:00

abstract：AIMS:Secretory carcinoma (SC) is a rare histological type of breast cancer, and ETV6-NTRK3 gene fusion is highly specific to it. The differential diagnoses of SC include acinic cell carcinoma (ACCA) and cystic hypersecretory carcinoma (CHC), as well as invasive ductal carcinoma (IDC). For patients with these rare but d...

journal_title：Histopathology

authors： Osako T,Takeuchi K,Horii R,Iwase T,Akiyama F

更新日期：2013-10-01 00:00:00

abstract：AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...

journal_title：Histopathology

authors： De Cecco L,Gariboldi M,Reid JF,Lagonigro MS,Tamborini E,Albertini V,Staurengo S,Pilotti S,Pierotti MA

更新日期：2005-03-01 00:00:00

abstract：:Identical adolescent Negro twins presented with multiple bilateral breast adenomata. There were three pure tubular adenomata, one mixed tubular and fibroadenoma, four glandular fibroadenomata and one typical intracanalicular fibroadenoma. Tubular adenomata are exceedingly rare and this report adds a further three to t...

journal_title：Histopathology

authors： Morris JA,Kelly JF

更新日期：1982-09-01 00:00:00

abstract：AIMS:Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare malignancy, and its clinicopathological characteristics have not yet been fully elucidated. This study aimed to elucidate the clinicopathological features of CAED through immunostaining of enteroblastic lineage markers alpha-fetoprotein ...

journal_title：Histopathology

authors： Murakami T,Yao T,Yatagai N,Yamashiro Y,Saito T,Sakamoto N,Nagahara A

更新日期：2020-01-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：AIMS:To determine the expression of matrix metalloproteinases (MMPs)-2, -7 and -9 and beta-catenin in uterine serous carcinoma (USC) and endometrioid endometrial carcinoma (EEC) and to investigate any difference in expression between EEC and USC which might explain the mechanism of invasion and aggressive behaviour of ...

journal_title：Histopathology

authors： Monaghan H,MacWhinnie N,Williams AR

更新日期：2007-02-01 00:00:00

abstract：AIMS:To study the pathogenesis of tumoral calcinosis (TC), we investigated 111 cases registered in Zaire over 30 years. METHODS AND RESULTS:The patients were 108 black Africans and three Caucasians between 3 and 74 years of age (mean, 37.7; median, 39). The gender was known in 33 males and 46 females; in 79 the gender...

journal_title：Histopathology

authors： Pakasa NM,Kalengayi RM

更新日期：1997-07-01 00:00:00

abstract：:Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are derived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis i...

journal_title：Histopathology

authors： Tan SY,Pepys MB

更新日期：1994-11-01 00:00:00

abstract：AIMS:Small cell (neuroendocrine) carcinoma of the urinary bladder is clinically more aggressive than urothelial (transitional cell) carcinoma. We have investigated the immunohistochemical markers most useful in diagnosing small cell carcinoma in bladder. METHODS AND RESULTS:We evaluated the expression of chromogranin ...

journal_title：Histopathology

authors： Iczkowski KA,Shanks JH,Allsbrook WC,Lopez-Beltran A,Pantazis CG,Collins TR,Wetherington RW,Bostwick DG

更新日期：1999-08-01 00:00:00

abstract：:The distribution of epithelial L1 antigen was evaluated in 139 bronchogenic carcinomas which had been classified by a panel of pathologists according to the WHO recommendation of 1981. L1 was not found in three large cell and 13 small cell carcinomas, but it was expressed by tumour cells in 67 of 69 squamous cell carc...

journal_title：Histopathology

authors： Dale I,Brandtzaeg P

更新日期：1989-05-01 00:00:00

abstract：AIMS:Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). Oxaliplatin-associated liver toxicity has been reported and can affect clinical practice, but studies on its prevalence and a full pathological description are lacking....

journal_title：Histopathology

authors： Rubbia-Brandt L,Lauwers GY,Wang H,Majno PE,Tanabe K,Zhu AX,Brezault C,Soubrane O,Abdalla EK,Vauthey JN,Mentha G,Terris B

更新日期：2010-03-01 00:00:00

abstract：AIMS:To investigate the prognostic significance of chromosomal alterations in colorectal cancer patients. Histopathological tumour classification is still considered to be the gold standard for the characterization of solid tumours. However, it is well known that such established parameters do not satisfactorily predic...

journal_title：Histopathology

authors： Knösel T,Schlüns K,Stein U,Schwabe H,Schlag PM,Dietel M,Petersen I

更新日期：2003-10-01 00:00:00

abstract：AIMS:To discern the differences in expression profiling of two histological subtypes of colorectal carcinoma (CRC) arising from the serrated route (serrated adenocarcinoma (SAC) and CRC showing histological and molecular features of a high level of microsatellite instability (hmMSI-H) both sharing common features (fema...

journal_title：Histopathology

authors： García-Solano J,Turpin-Sevilla MDC,García-García F,Carbonell-Muñoz R,Torres-Moreno D,Conesa A,Conesa-Zamora P

更新日期：2019-10-01 00:00:00

abstract：:A case of squamous cell carcinoma of the lung showing extensive spindle transformation is presented. On light microscopy, the tumour showed sheets and fascicles of elongated fusiform cells resulting in a growth pattern which closely resembled a sarcoma. Immunocytochemistry using tissue-specific antibodies against inte...

journal_title：Histopathology

authors： Suster S,Huszar M,Herczeg E

更新日期：1987-08-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：:Alongside histomorphology and immunohistochemistry, molecular pathology is now established as one of the cornerstones in the tissue diagnosis of bone tumours. We describe the principal molecular pathological techniques employed, and each of the bone tumour entities where their identified characteristic molecular patho...

journal_title：Histopathology

authors： Puls F,Niblett AJ,Mangham DC

更新日期：2014-03-01 00:00:00

abstract：AIMS:The clinical outcome of patients with locally advanced rectal cancer who undergo neoadjuvant chemoradiotherapy (CRT) is influenced by the tumour response to treatment, which is reflected by tumour regression grade and post-treatment (y) TNM stage. Little is known about the prognostic value of pretreatment histopat...

journal_title：Histopathology

authors： Reggiani Bonetti L,Lionti S,Domati F,Pagliani G,Mattioli E,Barresi V

更新日期：2017-09-01 00:00:00

abstract：AIMS:NTRK gene rearranged sarcomas are emerging as a distinct class of sarcomas of particular importance in the era of targeted therapy. In this study we used Array Comparative Genomic Hybridisation (aCGH) to explore the cytogenetic profile of 6 adult soft tissue sarcomas harbouring NTRK gene fusions. METHODS AND RESU...

journal_title：Histopathology

authors： Vargas AC,Mesbah Ardakani N,Wong DD,Maclean FM,Kattampallil J,Boyle R,Santos L,Gill AJ

更新日期：2020-10-31 00:00:00

abstract：:Human T-cell leukaemia/lymphoma virus type 1 (HTLV-1), a causative virus of adult T-cell leukaemia/lymphoma (ATLL), is known to be transmitted by breast-feeding. Using a monoclonal antibody HML-1 which labels human intestinal intra-epithelial T lymphocytes, we have immunohistochemically examined ATLL tissues in order ...

journal_title：Histopathology

authors： Kitajima S,Tokunaga M,Goto M,Sato E,Utsunomiya A,Ohtsuka M,Hanada S,Arima T

更新日期：1994-09-01 00:00:00

abstract：AIMS:The expression of the inhibitor of apoptosis protein survivin has been shown to be a significant prognostic indicator in various human cancers. The aim was to assess its expression and prognostic value in salivary gland adenocarcinoma and muco-epidermoid carcinoma. METHODS AND RESULTS:Survivin expression was anal...

journal_title：Histopathology

authors： Stenner M,Weinell A,Ponert T,Hardt A,Hahn M,Preuss SF,Guntinas-Lichius O,Klussmann JP

更新日期：2010-11-01 00:00:00

abstract：:Two patients are described in each of whom metastatic prostatic carcinoma presented as a tumour of the parotid gland. In one, primary prostate cancer had been diagnosed three years prior to the appearance of what was believed clinically to be an unrelated salivary lesion. In the other a neck swelling was the first ind...

journal_title：Histopathology

authors： Simpson RH,Skálová A

更新日期：1997-01-01 00:00:00

abstract：AIMS:There have been several cell kinetic studies of thymoma, but the effectiveness of using Ki67 antibody as a tool to measure proliferative activity in this tumour was rarely evaluated. We carried out an immuno-histochemical study using this antibody to assess the clinicopathological correlation and the prognostic si...

journal_title：Histopathology

authors： Pan CC,Ho DM,Chen WY,Huang CW,Chiang H

更新日期：1998-11-01 00:00:00

abstract：:Two cases of tubulovillous adenoma and adjacent colonic mucosa were studied in which intestinal spirochaetosis had heavily colonized the non-neoplastic but not the neoplastic epithelium. Ultrastructural and histochemical studies were performed and we postulate that the reason for this disparity is the normal microvill...

journal_title：Histopathology

authors： Coyne JD,Curry A,Purnell P,Haboubi NY

更新日期：1995-10-01 00:00:00

abstract：AIMS:We present three distinctive uterine tumours which exhibited immature smooth muscle differentiation mimicking smooth muscle cells of the fetal uterus. METHODS AND RESULTS:The patients were 45, 46 and 49 years old, and all of them had simple hysterectomies. Grossly, all tumours were present in the uterine body, an...

journal_title：Histopathology

authors： Watanabe K,Ogura G,Suzuki T

更新日期：2003-04-01 00:00:00

abstract：AIMS:Tumour-infiltrating lymphocytes (TILs) are an important component of the immune response to cancer and have a prognostic value in breast cancer. Although several studies have investigated the role of T lymphocytes in breast cancer, the role of B lymphocytes (TIL-Bs) in ductal carcinoma in situ (DCIS) remains uncer...

journal_title：Histopathology

authors： Miligy I,Mohan P,Gaber A,Aleskandarany MA,Nolan CC,Diez-Rodriguez M,Mukherjee A,Chapman C,Ellis IO,Green AR,Rakha EA

更新日期：2017-08-01 00:00:00

abstract：:Hyaline eosinophilic globules have so far been described in a restricted variety of tumour types. We have noted their presence in a variety of gynaecological malignancies, in particular mixed Müllerian tumours and other epithelial ovarian tumours. We therefore studied their incidence and distribution in a series of ma...

journal_title：Histopathology

authors： al-Nafussi AI,Hughes DE,Williams AR

更新日期：1993-12-01 00:00:00