Dilated (congestive) cardiomyopathy: a syndrome of severe cardiac dysfunction with remarkably few morphological features of myocardial damage.

abstract：AIMS:SOX11 is known as an essential transcription factor for regulating neurogenesis. Recently, SOX11 has been suggested to be a diagnostic marker and oncogene because of its significant expression in mantle cell lymphoma (MCL). However, SOX11 expression in other tumour types has not yet been extensively studied. METH...

journal_title：Histopathology

authors： Xu S,Dong Y,Huo Z,Yu L,Xue J,Wang G,Duan Y

更新日期：2019-02-01 00:00:00

abstract：:Three cases of angiolymphoid hyperplasia with eosinophilia are reported at the site of tetanus toxoid vaccination. All presented as nodules on the upper arm, a known adverse effect of the vaccine following superficial inoculation. Histologically the nodules showed numerous small and medium sized vessels, some lined by...

journal_title：Histopathology

authors： Akosa AB,Ali MH,Khoo CT,Evans DM

更新日期：1990-06-01 00:00:00

abstract：AIMS:A systematic review of published reports that have evaluated the ability of immunohistochemistry and argyrophil nucleolar organizing region (AgNOR) staining to distinguish between benign and malignant pleural disease. METHODS:Nineteen relevant papers published during the period 1979-2005 were identified. Individu...

journal_title：Histopathology

authors： King J,Thatcher N,Pickering C,Hasleton P

更新日期：2006-12-01 00:00:00

abstract：:The CD30 antigen is a characteristic phenotypic feature of Sternberg-Reed and Hodgkin cells and is also found in a subset of large cell non-Hodgkin's lymphomas. The finding of CD30 positive cells in some centroblastic/centrocytic (cb/cc) follicular lymphomas prompted us to characterize the presence and distribution of...

journal_title：Histopathology

authors： Piris M,Gatter KC,Mason DY

更新日期：1991-01-01 00:00:00

abstract：:Thirty kidney tumours of various histological type were histochemically investigated under the light microscope by means of the ABC-method. We used four biotinylated lectins which are known to bind also to normal renal tubular epithelial cells of different nephron segments. The nuclear grade, the histological growth p...

journal_title：Histopathology

authors： Ulrich W,Horvat R,Krisch K

更新日期：1985-10-01 00:00:00

abstract：:Fifteen cases of non-Hodgkin's lymphoma of the anterior mediastinum are reported. In the first group of four, fresh tissue was available and immunohistochemical studies demonstrated their B-cell origin, with monotypic immunoglobulin production in two. Only fixed tissue was available in the second group of 11 patients....

journal_title：Histopathology

authors： Addis BJ,Isaacson PG

更新日期：1986-04-01 00:00:00

abstract：:The new World Health Organization (WHO) classification of soft tissue tumours was published in early 2013, almost 11 years after the previous edition. While the number of newly recognized entities included for the first time is fewer than that in 2002, there have instead been substantial steps forward in molecular gen...

journal_title：Histopathology

authors： Fletcher CD

更新日期：2014-01-01 00:00:00

abstract：AIMS:Orientation and digital analysis of the biliary remnants in the resected porta hepatis in infants with biliary atresia. METHODS AND RESULTS:Samples were orientated intra-operatively then stained with haematoxylin and eosin and immunostained for cytokeratin 7 (CK7). Sections were then digitized and analysed. Most ...

journal_title：Histopathology

authors： Shalaby A,Hajhosseiny R,Zen Y,Davenport M,Quaglia A

更新日期：2016-12-01 00:00:00

abstract：AIMS:To look for FOXL2 mutation in rare ovarian epithelial lesions showing stromal components with morphological features of adult granulosa cell tumour (AGCT). METHODS AND RESULTS:We report the 402C→G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations tha...

journal_title：Histopathology

authors： Singh N,Gilks CB,Huntsman DG,Smith JH,Coutts M,Ganesan R,McCluggage WG

更新日期：2014-04-01 00:00:00

abstract：AIMS:Pathology specimens often contain important margins that must be identified from gross examination of specimens through to microscopic examination. Commonly, unique colours of tissue-marking dye (TMD) are applied to each margin, which facilitates both macroscopic and microscopic identification. Various techniques ...

journal_title：Histopathology

authors： Williams AS,Dakin Haché K

更新日期：2014-05-01 00:00:00

abstract：AIMS:Maspin, a protein belonging to the serpin superfamily, is the product of a tumour suppressor gene. Tissue distribution studies have shown maspin expression in normal mammary epithelial cells, in the placenta, prostate, thymus, testis, oral cavity, small intestine, skin, and cornea. Maspin is expressed but down-reg...

journal_title：Histopathology

authors： Marioni G,Blandamura S,Giacomelli L,Calgaro N,Segato P,Leo G,Fischetto D,Staffieri A,de Filippis C

更新日期：2005-05-01 00:00:00

abstract：AIMS:Fibroadenomas (FAs) and phyllodes tumours (PTs) are fibroepithelial tumours. Mutations in MED12 exon 2 have been reported in FAs. This study investigated the MED12 mutations in a spectrum of fibroepithelial tumours. METHODS AND RESULTS:Using direct sequencing, we analysed MED12 exon 2 mutations on 121 samples, in...

journal_title：Histopathology

authors： Lien HC,Huang CS,Yang YW,Jeng YM

更新日期：2016-02-01 00:00:00

abstract：:High levels of bcl-2 protein have been found in a wide variety of human cancers. Since p53 gene inactivation occurs in over half of human cancers, it is possible that loss of p53-mediated repression of bcl-2 gene expression accounts, at least in part, for the frequent abnormalities in bcl-2 protein production seen in ...

journal_title：Histopathology

authors： Harn HJ,Ho LI,Liu CA,Liu GC,Lin FG,Lin JJ,Chang JY,Lee WH

更新日期：1996-04-01 00:00:00

abstract：:Nine cases of Mullerian adenosarcoma of the uterine body, first defined in 1974 by Clement & Scully, are described. The tumour usually occurs in elderly women and appears macroscopically as a polypoid mass filling the uterine cavity. Histologically these neoplasms are characterized by having a benign epithelial compon...

journal_title：Histopathology

authors： Fox H,Harilal KR,Youell A

更新日期：1979-05-01 00:00:00

abstract：AIMS:To investigate whether localization of beta-catenin is helpful in differentiating primary ovarian mucinous carcinoma and colorectal adenocarcinoma metastatic to the ovary. Extra-ovarian cancers which metastasize to the ovaries, especially from colorectal adenocarcinoma, frequently mimic primary ovarian carcinomas,...

journal_title：Histopathology

authors： Chou YY,Jeng YM,Kao HL,Chen T,Mao TL,Lin MC

更新日期：2003-08-01 00:00:00

abstract：:Pulmonary blastomas and carcinosarcomas are uncommon tumours, accounting for less than 1% of all lung neoplasms. Three previously described mixed epithelial and mesenchymal tumours having both adult and embryonal elements were termed 'transitional'. We report a similar case and evaluate the application of the term 'tr...

journal_title：Histopathology

authors： Olenick SJ,Fan CC,Ryoo JW

更新日期：1994-08-01 00:00:00

abstract：AIMS:To investigate the pathology of colectomy specimens, from patients presenting with lower gastrointestinal haemorrhage, who had undergone preoperative mesenteric angiography. The angiography diagnoses ranged from active bleeding of unknown aetiology to angiodysplasia. METHODS AND RESULTS:The macroscopic and micros...

journal_title：Histopathology

authors： Mudhar HS,Balsitis M

更新日期：2005-01-01 00:00:00

abstract：:A case is reported of squamous carcinoma of the peri-anal region arising in a giant condyloma. In situ DNA hybridization showed human papillomavirus (HPV) types 6 and 11. These HPV types are commonly demonstrated in ano-genital condylomas but have not previously been reported in association with malignant change at th...

journal_title：Histopathology

authors： Wells M,Robertson S,Lewis F,Dixon MF

更新日期：1988-03-01 00:00:00

abstract：:One hundred cases of routinely fixed and processed non-Hodgkin's lymphoma from Nigeria were immunostained with a small panel of monoclonal antibodies against B-, T- and macrophage antigens. The aims of the study were to assess the suitability of stored material from a country like Nigeria for immunohistochemical exami...

journal_title：Histopathology

authors： Thomas JO,Rafindadi A,Heryet A,Jones M,Gatter KC,Mason DY

更新日期：1991-06-01 00:00:00

abstract：AIMS:Macrophage colony-stimulating factor (M-CSF) binds to colony-stimulating factor-1 receptor (CSF-1R) and stimulates proliferation and differentiation of monocytes, macrophages and their bone marrow progenitors. M-CSF, CSF-1R, the macrophage marker CD68, and the pan T-lymphocyte marker CD3 are increased in many huma...

journal_title：Histopathology

authors： Richardsen E,Uglehus RD,Due J,Busch C,Busund LT

更新日期：2008-07-01 00:00:00

abstract：:Valve replacement started in 1960, with the surgeon now having a significant variety of prosthetic heart valves from which to choose. These valves are broadly divided into mechanical heart valves (MHV) and bioprosthetic heart valves (BHV). Improvements in the performance and ease of usage of BHV without the need for a...

journal_title：Histopathology

authors： Siddiqui RF,Abraham JR,Butany J

更新日期：2009-08-01 00:00:00

abstract：AIMS:Prostate gland volume is generally assessed by transrectal ultrasound examination or magnetic resonance imaging at the time of prostatic biopsy or pre-brachytherapy planning. The volume is most commonly measured using the formula, prostate volume = height x width x length x pi/6, which is derived considering the g...

journal_title：Histopathology

authors： Varma M,Morgan JM

更新日期：2010-07-01 00:00:00

abstract：:An immunohistochemical study of non-small cell lung carcinoma using PC10, a monoclonal antibody against PCNA, was performed on tissues routinely processed with formalin fixation and paraffin embedding. The PCNA labelling index and mitotic index were determined from sections of these tissues. Tumours showed a high mean...

journal_title：Histopathology

authors： Theunissen PH,Leers MP,Bollen EC

更新日期：1992-03-01 00:00:00

abstract：:Increasingly more coherent data on the molecular characteristics of benign breast lesions and breast cancer precursors have led to the delineation of new multistep pathways of breast cancer progression through genotypic-phenotypic correlations. It has become apparent that oestrogen receptor (ER)-positive and -negative...

journal_title：Histopathology

authors： Lopez-Garcia MA,Geyer FC,Lacroix-Triki M,Marchió C,Reis-Filho JS

更新日期：2010-08-01 00:00:00

abstract：AIMS:AP2alpha (TFAP2A) and AP2gamma (TFAP2G) transcription factors have been implicated in the control of proliferation, differentiation and apoptosis of normal breast epithelium and in breast cancer. The aim of this study was to provide a comprehensive analysis of the expression patterns of TFAP2A and TFAP2G in the de...

journal_title：Histopathology

authors： Friedrichs N,Steiner S,Buettner R,Knoepfle G

更新日期：2007-12-01 00:00:00

abstract：AIMS:Eleven cases of cutaneous perineurioma were studied to further characterize the histological features of this entity. METHODS AND RESULTS:The histological and immunocytochemical features of 11 cases of cutaneous perineurioma were studied and detailed by two pathologists. Clinical data were obtained from the refer...

journal_title：Histopathology

authors： Robson AM,Calonje E

更新日期：2000-10-01 00:00:00

abstract：AIMS:The purpose of this study was to examine the occurrence of CD44 isoforms in breast carcinomas and their role in predicting clinical outcome. METHODS AND RESULTS:Shock-frozen tumour tissues from 110 patients with breast carcinoma were examined by immunohistochemistry using antibodies directed against CD44s, v5, v6...

journal_title：Histopathology

authors： Berner HS,Suo Z,Risberg B,Villman K,Karlsson MG,Nesland JM

更新日期：2003-06-01 00:00:00

abstract：AIMS:BCOR-CCNB3 sarcoma is a genetically defined undifferentiated malignancy with Ewing sarcoma (ES)-like round cells, and preferentially affects the bones of male adolescents. Sarcomas harbouring BCOR-CCNB3 rarely arise from soft tissues; therefore, we aimed to report four cases to expand the clinicopathological spect...

journal_title：Histopathology

authors： Li WS,Liao IC,Wen MC,Lan HH,Yu SC,Huang HY

更新日期：2016-11-01 00:00:00

abstract：AIM:Primary cutaneous neuroendocrine carcinoma, or Merkel cell carcinoma (MCC), cannot be distinguished morphologically from small-cell neuroendocrine carcinomas (SmCC) from other sites. Immunohistochemistry is required to confirm cutaneous origin, and is also used for detection of sentinel lymph node (SLN) metastases ...

journal_title：Histopathology

authors： Stanoszek LM,Chan MP,Palanisamy N,Carskadon S,Siddiqui J,Patel RM,Harms KL,Lowe L,Fullen DR,Harms PW

更新日期：2019-02-01 00:00:00

abstract：AIMS:HER2 testing of invasive breast cancer by in-situ hybridization guides therapy decisions. Probing HER2 and centromere of chromosome 17 (cen17) simultaneously is supposed to reveal both a potential HER2 gene amplification and polysomy 17. However, a considerable number of breast cancer patients with quasi polysomy ...

journal_title：Histopathology

authors： Holzschuh MA,Czyz Z,Hauke S,Inwald EC,Polzer B,Brockhoff G

更新日期：2017-10-01 00:00:00