Bioprosthetic heart valves: modes of failure.

Abstract:

:Valve replacement started in 1960, with the surgeon now having a significant variety of prosthetic heart valves from which to choose. These valves are broadly divided into mechanical heart valves (MHV) and bioprosthetic heart valves (BHV). Improvements in the performance and ease of usage of BHV without the need for anticoagulant therapy are among the desired features of BHV and hence the increasingly preferred choice over their mechanical counterparts. However, with increased use the post-implantation complications have become more apparent, and these include: calcification, cusp tears, pannus growth, infective endocarditis, valve thrombosis and other factors specific to valve type. In this review we describe these complications in order to bring awareness among surgeons, clinicians and pathologists. Diagnosis, treatment and preventive measures, if taken in a timely manner, can help reduce their impact and further enhance the quality of life of patients with prosthetic heart valves.

journal_name

Histopathology

journal_title

Histopathology

authors

Siddiqui RF,Abraham JR,Butany J

doi

10.1111/j.1365-2559.2008.03190.x

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

135-44

issue

2

eissn

0309-0167

issn

1365-2559

pii

HIS3190

journal_volume

55

pub_type

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