Immunophenotyping of Nigerian cases of non-Hodgkin's lymphomas on paraffin sections.

abstract：:Hyaline eosinophilic globules have so far been described in a restricted variety of tumour types. We have noted their presence in a variety of gynaecological malignancies, in particular mixed Müllerian tumours and other epithelial ovarian tumours. We therefore studied their incidence and distribution in a series of ma...

journal_title：Histopathology

authors： al-Nafussi AI,Hughes DE,Williams AR

更新日期：1993-12-01 00:00:00

abstract：AIMS:To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes. METHODS AND RESULTS:RAD51 expression identified immunohistochemically was compared between prostatic cancers occ...

journal_title：Histopathology

authors： Mitra A,Jameson C,Barbachano Y,Sanchez L,Kote-Jarai Z,Peock S,Sodha N,Bancroft E,Fletcher A,Cooper C,Easton D,IMPACT Steering Committee and IMPACT and EMBRACE Collaborators.,Eeles R,Foster CS

更新日期：2009-12-01 00:00:00

abstract：AIMS:Pathological staging in penectomies may be difficult due to the anatomical complexity of penile anatomy, and may be additionally challenging due to the low volume at most institutions. Our study aimed to assess the feasibility of whole-mount processing for penectomy specimens. METHODS AND RESULTS:A 7-year retrosp...

journal_title：Histopathology

authors： Ebel JJ,Shabsigh A,Sharp DS,Zynger DL

更新日期：2013-07-01 00:00:00

abstract：AIMS:To investigate the expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors and decoy receptors, including osteoprotegerin (OPG) in infantile haemangioma (IH). METHODS AND RESULTS:Immunostaining, Western blotting and quantitative reverse transcription-polymerase chain react...

journal_title：Histopathology

authors： Vishvanath A,Itinteang T,Tan ST,Day DJ

更新日期：2011-09-01 00:00:00

abstract：AIMS:The recent recognition that ovarian carcinoma is composed of five distinct disease entities has served to increase the value of accurate histotyping. Reliable identification of histotypes is essential for the success of studies testing novel therapies, as well as for biomarker discovery research. The aim of this s...

journal_title：Histopathology

authors： Kommoss S,Gilks CB,Kommoss F,Chow C,Hilpert F,du Bois A,Köbel M,Huntsman DG,Anglesio M,Kalloger SE,Pfisterer J

更新日期：2013-11-01 00:00:00

abstract：AIMS:SOX2 is a key regulatory gene in embryonic stem cells. Although it has been implicated in cancer progression, its role in breast carcinoma is poorly understood. MATERIALS AND METHODS:Fifty-seven ductal carcinomas in situ (DCIS), 552 invasive breast carcinomas and 107 corresponding metastatic lymph nodes were eval...

journal_title：Histopathology

authors： Huang YH,Luo MH,Ni YB,Tsang JY,Chan SK,Lui PC,Yu AM,Tan PH,Tse GM

更新日期：2014-03-01 00:00:00

abstract：:A large variety of lymphoma types may develop as primary intestinal neoplasms in the small intestines or, less often, in the colorectum. Among these are a few entities such as enteropathy-associated T-cell lymphoma or immunoproliferative small intestinal disease that, essentially, do not arise elsewhere than in the ga...

journal_title：Histopathology

authors： Foukas PG,de Leval L

更新日期：2015-01-01 00:00:00

abstract：AIM:We evaluated the aetiology of ulcerative ileitis in a 77-year-old patient receiving BCG therapy for recurring bladder carcinoma. METHODS AND RESULTS:Histological examination, laboratory data and the clinical history allowed us to exclude a classical cause such as Crohn's disease, tuberculosis or ischaemia. The imp...

journal_title：Histopathology

authors： Satgé D,Pommepuy I,Hassan T,Goburdhun J,Flejou JF

更新日期：2002-09-01 00:00:00

abstract：AIMS:We aimed to define the clinicopathological characteristics of 29 primary sinonasal diffuse large B cell lymphoma (DLBCLsn ) in a series of 240 cases of DLBCL not otherwise specified [DLBCLall (NOS) ], including DLBCLsn training set (n = 11) and validation set (n = 18), and DLBCLnon-sn (n = 211). METHODS AND RESUL...

journal_title：Histopathology

authors： Carreras J,Kikuti YY,Beà S,Miyaoka M,Hiraiwa S,Ikoma H,Nagao R,Tomita S,Martin-Garcia D,Salaverria I,Sato A,Ichiki A,Roncador G,Garcia JF,Ando K,Campo E,Nakamura N

更新日期：2017-03-01 00:00:00

abstract：AIMS:The diagnosis of polymorphous low-grade adenocarcinoma (PLGA) remains difficult for general pathologists, particularly in cases of small biopsy samples. We aimed to characterize the histopathological spectrum and immunohistochemical aspects by using an accessible immunohistochemical panel of cytoskeletal proteins ...

journal_title：Histopathology

authors： Sedassari BT,Dos Santos HT,Pigatti FM,Martins Mussi MC,Tobouti PL,Altemani A,Sousa S

更新日期：2016-06-01 00:00:00

abstract：AIMS:Hodgkin lymphoma treatments are largely based on the generation of reactive oxygen species, but increased expression of antioxidant enzymes may contribute to chemoresistance. The aims of this study were: to define the extent and prognostic value of oxidative stress marker and antioxidant enzyme expression in Hodgk...

journal_title：Histopathology

authors： Bur H,Haapasaari KM,Turpeenniemi-Hujanen T,Kuittinen O,Auvinen P,Marin K,Koivunen P,Sormunen R,Soini Y,Karihtala P

更新日期：2014-09-01 00:00:00

abstract：AIMS:Tumour-infiltrating lymphocytes (TILs) are an important component of the immune response to cancer and have a prognostic value in breast cancer. Although several studies have investigated the role of T lymphocytes in breast cancer, the role of B lymphocytes (TIL-Bs) in ductal carcinoma in situ (DCIS) remains uncer...

journal_title：Histopathology

authors： Miligy I,Mohan P,Gaber A,Aleskandarany MA,Nolan CC,Diez-Rodriguez M,Mukherjee A,Chapman C,Ellis IO,Green AR,Rakha EA

更新日期：2017-08-01 00:00:00

abstract：AIMS:Owing to their close embryological relationship, soft tissue perineurioma and meningioma may closely mimic each other, not only histologically but also by immunohistochemistry. We aimed to compare the frequency of perineurial marker expression in these two entities, and to determine whether somatostatin receptor 2...

journal_title：Histopathology

authors： Agaimy A,Buslei R,Coras R,Rubin BP,Mentzel T

更新日期：2014-07-01 00:00:00

abstract：AIMS:A systematic review of published reports that have evaluated the ability of immunohistochemistry and argyrophil nucleolar organizing region (AgNOR) staining to distinguish between benign and malignant pleural disease. METHODS:Nineteen relevant papers published during the period 1979-2005 were identified. Individu...

journal_title：Histopathology

authors： King J,Thatcher N,Pickering C,Hasleton P

更新日期：2006-12-01 00:00:00

abstract：AIMS:To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC). METHODS AND RESULTS:This study consisted of 25 patients with PSC and bile duct neoplasia [16 with cholangiocarcinoma and nine with biliary intra-epithelial ...

journal_title：Histopathology

authors： Zen Y,Quaglia A,Heaton N,Rela M,Portmann B

更新日期：2011-12-01 00:00:00

abstract：:Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because ...

journal_title：Histopathology

authors： Sheppard MN

更新日期：1997-05-01 00:00:00

abstract：:A review of 1818 patients with cutaneous malignant melanoma revealed that for both patients with localized disease (clinical stage I) and those with regional lymph node metastases at first presentation (clinical stage II), ulceration of the primary lesion was a poor prognostic sign. Although ulcerated lesions tended t...

journal_title：Histopathology

authors： McGovern VJ,Shaw HM,Milton GW,McCarthy WH

更新日期：1982-07-01 00:00:00

abstract：:Waldeyer ring lymphomas belong to a category of tumours which has not yet been fully defined. Their relation to mucosa-associated lymphoid tissue (MALT) and other extranodal lymphomas remains largely unknown. We performed a clinicopathological retrospective study of 79 patients, and compared them with a series of MALT...

journal_title：Histopathology

authors： Menárguez J,Mollejo M,Carrión R,Oliva H,Bellas C,Forteza J,Martin C,Ruiz-Marcellán C,Morente M,Romagosa V

更新日期：1994-01-01 00:00:00

abstract：AIMS:The clinical outcome of patients with locally advanced rectal cancer who undergo neoadjuvant chemoradiotherapy (CRT) is influenced by the tumour response to treatment, which is reflected by tumour regression grade and post-treatment (y) TNM stage. Little is known about the prognostic value of pretreatment histopat...

journal_title：Histopathology

authors： Reggiani Bonetti L,Lionti S,Domati F,Pagliani G,Mattioli E,Barresi V

更新日期：2017-09-01 00:00:00

abstract：AIMS:Genome-wide next-generation sequencing has revealed several driver mutations and has allowed the establishment of a molecular taxonomy of gastric cancer. However, there are few detailed studies on the mutational spectrum of poorly cohesive gastric carcinoma. Thus, this study aim to investigate its mutation profile...

journal_title：Histopathology

authors： Kwon CH,Kim YK,Lee S,Kim A,Park HJ,Choi Y,Won YJ,Park DY,Lauwers GY

更新日期：2018-03-01 00:00:00

abstract：:Human T-cell leukaemia/lymphoma virus type 1 (HTLV-1), a causative virus of adult T-cell leukaemia/lymphoma (ATLL), is known to be transmitted by breast-feeding. Using a monoclonal antibody HML-1 which labels human intestinal intra-epithelial T lymphocytes, we have immunohistochemically examined ATLL tissues in order ...

journal_title：Histopathology

authors： Kitajima S,Tokunaga M,Goto M,Sato E,Utsunomiya A,Ohtsuka M,Hanada S,Arima T

更新日期：1994-09-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：:This review intends to update current knowledge regarding molecular cytogenetics in melanocytic tumours with a focus on cutaneous melanocytic lesions. Advantages and limitations of diverse, already established methods, such as (fluorescence) in situ hybridization and mutation analysis, to detect these cytogenetic alte...

journal_title：Histopathology

authors： Blokx WA,van Dijk MC,Ruiter DJ

更新日期：2010-01-01 00:00:00

abstract：AIMS:AP2alpha (TFAP2A) and AP2gamma (TFAP2G) transcription factors have been implicated in the control of proliferation, differentiation and apoptosis of normal breast epithelium and in breast cancer. The aim of this study was to provide a comprehensive analysis of the expression patterns of TFAP2A and TFAP2G in the de...

journal_title：Histopathology

authors： Friedrichs N,Steiner S,Buettner R,Knoepfle G

更新日期：2007-12-01 00:00:00

abstract：AIMS:NUT carcinoma, a rare aggressive tumor driven by NUTM1 rearrangements, often involves the lung/mediastinum and shows squamous differentiation. We encountered an index patient with a thoracic NUT carcinoma diagnosed by molecular testing, demonstrating extensive pleural involvement and diffuse TTF-1 expressions init...

journal_title：Histopathology

authors： Hung YP,Chen AL,Taylor MS,Huynh TG,Kem M,Selig MK,Nielsen GP,Lennerz JK,Azzoli CG,Dagogo-Jack I,Kradin RL,Mino-Kenudson M

更新日期：2020-11-24 00:00:00

abstract：:Lobular carcinoma in situ and atypical lobular hyperplasia were first described over 50 years ago. Despite this long incubation period, the biological nature of the lesions remains controversial. They are generally regarded as 'risk indicators' of invasive cancer rather than true precursor lesions. When first describe...

journal_title：Histopathology

authors： Lishman SC,Lakhani SR

更新日期：1999-09-01 00:00:00

abstract：AIM:Primary cutaneous neuroendocrine carcinoma, or Merkel cell carcinoma (MCC), cannot be distinguished morphologically from small-cell neuroendocrine carcinomas (SmCC) from other sites. Immunohistochemistry is required to confirm cutaneous origin, and is also used for detection of sentinel lymph node (SLN) metastases ...

journal_title：Histopathology

authors： Stanoszek LM,Chan MP,Palanisamy N,Carskadon S,Siddiqui J,Patel RM,Harms KL,Lowe L,Fullen DR,Harms PW

更新日期：2019-02-01 00:00:00

abstract：:We present a 27-year-old woman with non-systemic diffuse lymphangiomatosis of spleen and liver. The tumour consisted of capillary and cavernous lymphatic vessels located in abundant fibrous tissue. The vascular endothelium showed immunoreactivity for factor VIII-related antigen. A basal lamina could be demonstrated im...

journal_title：Histopathology

authors： Schmid C,Beham A,Uranüs S,Melzer G,Auböck L,Seewann HL,Klimpfinger M

更新日期：1991-05-01 00:00:00

abstract：AIMS:Prostate gland volume is generally assessed by transrectal ultrasound examination or magnetic resonance imaging at the time of prostatic biopsy or pre-brachytherapy planning. The volume is most commonly measured using the formula, prostate volume = height x width x length x pi/6, which is derived considering the g...

journal_title：Histopathology

authors： Varma M,Morgan JM

更新日期：2010-07-01 00:00:00

abstract：AIMS:To assess the immunophenotypic changes associated with epithelial-mesenchymal transition (EMT) in endocervical adenocarcinoma, and correlate the findings with tumour morphology including growth pattern. METHODS AND RESULTS:Twenty-seven endocervical adenocarcinomas were studied using a panel of immunohistochemical...

journal_title：Histopathology

authors： Stewart CJ,Crook ML,Little L,Louwen K

更新日期：2011-04-01 00:00:00