Abstract:
:Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because of marked nuclear pleomorphism on frozen section, were misdiagnosed as non-small cell carcinomas.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Sheppard MNdoi
10.1046/j.1365-2559.1997.5430778.xsubject
Has Abstractpub_date
1997-05-01 00:00:00pages
478-80issue
5eissn
0309-0167issn
1365-2559journal_volume
30pub_type
杂志文章相关文献
HISTOPATHOLOGY文献大全abstract:AIMS:To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC). METHODS AND RESULTS:This study consisted of 25 patients with PSC and bile duct neoplasia [16 with cholangiocarcinoma and nine with biliary intra-epithelial ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2011.04048.x
更新日期:2011-12-01 00:00:00
abstract::The International Collaboration on Cancer Reporting (ICCR) is a not-for-profit organisation sponsored by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Association of Pathologists in association with the Canadian Partnership Against Cancer, ...
journal_title:Histopathology
pub_type: 杂志文章,评审
doi:10.1111/his.13877
更新日期:2019-10-01 00:00:00
abstract:AIMS:The clinicopathological distinctiveness of nodal cytotoxic molecule (CM)-positive Epstein-Barr virus (EBV)-associated peripheral T cell lymphoma (PTCL) remains to be clarified. We investigated 26 patients with this lymphoma compared to nodal CM(+) EBV(-) PTCL (n = 39) and extranasal natural killer/T cell lymphoma ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2012.04199.x
更新日期:2012-08-01 00:00:00
abstract:AIMS:The majority of patients with Down syndrome (DS), trisomy 21, have morphologically abnormal thymuses and present with intrinsic immunological abnormalities affecting mainly the cellular immune response. The aim of this study was to examine whether the expression of functionally important molecules is altered in th...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12642
更新日期:2015-08-01 00:00:00
abstract:AIMS:To determine the expression of matrix metalloproteinases (MMPs)-2, -7 and -9 and beta-catenin in uterine serous carcinoma (USC) and endometrioid endometrial carcinoma (EEC) and to investigate any difference in expression between EEC and USC which might explain the mechanism of invasion and aggressive behaviour of ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2007.02612.x
更新日期:2007-02-01 00:00:00
abstract::Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1986.tb02520.x
更新日期:1986-07-01 00:00:00
abstract::Twenty-nine cases of non-Hodgkin's lymphoma of low-grade malignancy in a European population were investigated for the presence of bcl-2 and bcl-1 gene rearrangement. The cases were classified according to the Kiel classification. It was shown that bcl-2 gene rearrangements were exclusively confined to centroblastic-c...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1991.tb00007.x
更新日期:1991-08-01 00:00:00
abstract:AIMS:bcl-2-associated transcription factor 1 (BCLAF1) is a nuclear protein that binds to bcl-related proteins and can induce apoptosis and autophagy. The aim of this study was to investigate the expression of BCLAF1 in a series of rectal cancers following neoadjuvant therapy. METHODS AND RESULTS:Immunohistochemistry w...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12780
更新日期:2016-03-01 00:00:00
abstract:AIMS:In this study, we aimed to investigate the clinicopathological features of CD4+ and/or CD56+ immature haematolymphoid malignancy (iHLM), including blastic plasmacytoid dendritic cell neoplasm (BPDCN). METHODS AND RESULTS:We analysed the clinicopathological features of 46 patients diagnosed consecutively with CD4+...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13340
更新日期:2017-12-01 00:00:00
abstract:AIMS: Ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) exhibit frequent RUNX3 inactivation by promoter hypermethylation and protein mislocalization. The aim of this study was to analyse columnar cell lesions (CCLs) to further characterize RUNX3 involvement in breast carcinogenesis. METHODS AND RESU...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2010.03675.x
更新日期:2010-10-01 00:00:00
abstract:AIMS:Diffuse large B-cell lymphoma (DLBCL) usually proliferates effacing lymph follicles. In occasional cases, tumour cells show an interfollicular pattern of proliferation preserving lymph follicles. The aim was to analyse clinicopathological findings in DLBCL showing an interfollicular pattern of proliferation to det...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2008.03018.x
更新日期:2008-05-01 00:00:00
abstract:AIMS:Y-box binding protein-1 (YB-1) is known to modulate gene transcription and protein translation, as well as cellular response to drug treatment. The aim of this study is to correlate YB-1 protein expression levels with clinicopathological parameters in intestinal-type gastric cancer tissue samples (as categorized b...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12570
更新日期:2015-03-01 00:00:00
abstract:AIMS:NTRK gene rearranged sarcomas are emerging as a distinct class of sarcomas of particular importance in the era of targeted therapy. In this study we used Array Comparative Genomic Hybridisation (aCGH) to explore the cytogenetic profile of 6 adult soft tissue sarcomas harbouring NTRK gene fusions. METHODS AND RESU...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.14295
更新日期:2020-10-31 00:00:00
abstract::A Sertoli-Leydig cell tumour of testis presented some diagnostic difficulties. The tumour cells showed strong expression of S-100 antigen. Preliminary study of non-neoplastic testis suggests that Leydig cells and, to a lesser extent, Sertoli cells express S-100 antigen; its localization may be of value in the diagnosi...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1989.tb01634.x
更新日期:1989-12-01 00:00:00
abstract:AIMS:To study the relevance of periostin, known to be involved in epithelial-mesenchymal transition (EMT), in hepatocellular and bile duct cancer. METHODS AND RESULTS:Immunohistochemical periostin expression was semiquantitatively analysed in normal liver tissue (n = 20), hepatocellular carcinoma (HCC; n = 91), liver-...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2010.03527.x
更新日期:2010-04-01 00:00:00
abstract:AIMS:p53 immunostaining in Barrett's oesophagus (BO) has been shown to be predictive of progression, but data regarding its generalizability to routine practice are lacking. This study compared the reliability of p53 and dysplasia interpretation and grading. METHODS AND RESULTS:Seventy-two cases encompassing the full ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12956
更新日期:2016-09-01 00:00:00
abstract::Nine cases of Mullerian adenosarcoma of the uterine body, first defined in 1974 by Clement & Scully, are described. The tumour usually occurs in elderly women and appears macroscopically as a polypoid mass filling the uterine cavity. Histologically these neoplasms are characterized by having a benign epithelial compon...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1979.tb02994.x
更新日期:1979-05-01 00:00:00
abstract:AIMS:Survivin, a newly discovered member of the inhibitor of apoptosis protein family, is suggested to be involved in liver carcinogenesis. The aim was to investigate the clinical significance of survivin expression in resected hepatocellular carcinoma (HCC) and paired adjacent non-tumour tissue. METHODS AND RESULTS:I...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2007.02738.x
更新日期:2007-08-01 00:00:00
abstract:AIMS:To develop a method to preserve lipids in formalin-fixed tissues for staining in paraffin sections, and to illustrate its use in lung and brain of a fat embolism case, and in examples of fatty liver and atheroma. METHODS AND RESULTS:A saturated solution of linoleic acid in 70% ethylene glycol was prepared and tis...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1046/j.1365-2559.2002.01414.x
更新日期:2002-07-01 00:00:00
abstract::Malignant lymphomas can be first detected in some patients in endoscopic biopsies of the gastrointestinal (GI) tract. However, their recognition and accurate classification often pose problems for the pathologist for several reasons. First, the small sampling size limits pattern recognition and the number of ancillary...
journal_title:Histopathology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2559.2006.02571.x
更新日期:2007-01-01 00:00:00
abstract:AIMS:Pulmonary fibrosis in acute and chronic lung disease has been much investigated, but little attention has been directed at the elastic tissue in these situations. Our aim was to verify whether elastic deposition accompanies collagen deposition in the repairing process of acute and chronic lung injury. METHODS AND...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1046/j.1365-2559.2000.00992.x
更新日期:2000-11-01 00:00:00
abstract::In reviewing a large series of soft tissue tumours, seven cases of benign plexiform schwannoma have been retrieved. These were solitary lesions, not associated with von Recklinghausen's neurofibromatosis, which arose in the dermis or subcutaneous tissue, predominantly in young adults. None has recurred. While the schw...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1986.tb02595.x
更新日期:1986-09-01 00:00:00
abstract:AIMS:Patients with aggressive CD8+ cutaneous T-cell lymphomas (CTCLs) progress rapidly and respond poorly to therapy. Confounding treatment planning, there is clinicopathological overlap between aggressive CD8+ CTCLs and other lymphoproliferative disorders (LPDs). Hence, improved diagnostic methods and therapeutic opti...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13960
更新日期:2020-01-01 00:00:00
abstract:AIM:Dual-colour chromogenic in-situ hybridization (dc-CISH) is an emerging methodology for characterizing genomic alterations. This study was aimed at evaluating the performance of a dc-CISH kit (ZytoVision) in determining human epidermal growth factor receptor 2 (HER2) status in breast cancer. METHODS AND RESULTS:Two...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2011.04037.x
更新日期:2011-11-01 00:00:00
abstract:AIMS:Primary pulmonary sarcoma is rare, and frequently creates diagnostic challenges. We describe two cases of primary pulmonary spindle cell sarcoma in which a molecular approach using archival paraffin-embedded tissue was proved to aid diagnosis. METHODS AND RESULTS:Both patients had huge masses replacing the upper ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1046/j.1365-2559.1999.00630.x
更新日期:1999-03-01 00:00:00
abstract::We studied kidney sections from 15 cases of polyarteritis using an immunocytochemical technique to demonstrate cells containing immunoreactive renin. Ten cases of classical polyarteritis nodosa showed hyperplasia of renin-containing cells in areas of renal cortex with histological evidence of ischaemia--appearances in...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1990.tb01137.x
更新日期:1990-04-01 00:00:00
abstract::Some antigenic determinants can be preserved in tissues after plastic embedding. In the present study liver tissue was fixed with glutaraldehyde or paraformaldehyde, dehydrated with ethanol and toluene and embedded in araldite which was then polymerized at 37 degrees C. Immunofluorescence was performed on semi-thin se...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1977.tb01674.x
更新日期:1977-09-01 00:00:00
abstract::This study demonstrates the presence of three antigens in glandular metaplasia occurring in patients with cholecystitis and cholelithiasis: specifically carcinoembryonic antigen (CEA), large intestinal mucin antigen (LIMA) and small intestinal mucin antigen (SIMA). These antigens could not be detected in normal gall b...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1981.tb01788.x
更新日期:1981-05-01 00:00:00
abstract:AIMS:Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in endometrial carcinomas and its pr...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12047
更新日期:2013-03-01 00:00:00
abstract:AIMS:Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in gallbladder tissues. I...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13797
更新日期:2019-03-01 00:00:00