C-C chemokine receptor 4 expression in CD8+ cutaneous T-cell lymphomas and lymphoproliferative disorders, and its implications for diagnosis and treatment.

abstract：AIMS:Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in gallbladder tissues. I...

journal_title：Histopathology

authors： Espinoza JA,Riquelme I,Sagredo EA,Rosa L,García P,Bizama C,Apud-Bell M,Leal P,Weber H,Benavente F,Vargas S,Romero D,Kalergis AM,Roa JC

更新日期：2019-03-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：AIMS:Pulmonary chondromas, which are rare cartilaginous neoplasms that often arise in the setting of Carney triad, are morphologically similar to pulmonary hamartomas, which are much more common. There is evidence that succinate dehydrogenase (SDH) deficiency drives neoplasia in patients with Carney triad, and SDHB imm...

journal_title：Histopathology

authors： Chatzopoulos K,Fritchie KJ,Aubry MC,Carney JA,Folpe AL,Boland JM

更新日期：2019-12-01 00:00:00

abstract：:This study evaluates the usefulness of a combined cytological and histological approach to the diagnosis of hepatocellular carcinoma (HCC) when applied to fine needle biopsy specimens obtained under ultrasonic guidance. The material, aspirated from 51 focal liver lesions, was handled in such a way that there was suffi...

journal_title：Histopathology

authors： Zainol H,Sumithran E

更新日期：1993-06-01 00:00:00

abstract：:The aim of this study is to provide a long-term follow-up of patients with tubular carcinoma and to investigate whether the separation of the mixed type of tubular carcinoma, tubular component more than 75%, from invasive ductal carcinoma with a major tubular component (ductal carcinoma MTC), tubular component 50 to 7...

journal_title：Histopathology

authors： Carstens PH,Greenberg RA,Francis D,Lyon H

更新日期：1985-03-01 00:00:00

abstract：AIMS:There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. ...

journal_title：Histopathology

authors： Oxley J,Simpkin A,Goepel J,Varma M,Griffiths D,Grigor K,Mayer N,Warren A,Deshmukh N,Bhattarai S,Dormer J,Hounsome L,Adamczyk LA,Metcalfe C,Lane JA,Davis M,Donovan JL,Neal DE,Hamdy FC,Robinson MC,ProtecT Study Grou

更新日期：2015-02-01 00:00:00

abstract：AIMS:Progressive changes have been reported in lymph nodes in HIV infection, but few accounts describe altered splenic histology at different stages of the disease. Investigation of splenic changes accompanying the progressive CD4+ T-cell depletion that occurs in HIV infection could shed light on normal immunological i...

journal_title：Histopathology

authors： Wilkins BS,Davis Z,Lucas SB,Delsol G,Jones DB

更新日期：2003-02-01 00:00:00

abstract：AIMS:Survivin, a newly discovered member of the inhibitor of apoptosis protein family, is suggested to be involved in liver carcinogenesis. The aim was to investigate the clinical significance of survivin expression in resected hepatocellular carcinoma (HCC) and paired adjacent non-tumour tissue. METHODS AND RESULTS:I...

journal_title：Histopathology

authors： Chau GY,Lee AF,Tsay SH,Ke YR,Kao HL,Wong FH,Tsou AP,Chau YP

更新日期：2007-08-01 00:00:00

abstract：:While the histological grade of a renal cell carcinoma is of prognostic significance there is poor concordance amongst pathologists in the use of these grading systems. Many grading systems have been described, but none has achieved widespread acceptance. The objective of this study was to assess the degree of interob...

journal_title：Histopathology

authors： Lanigan D,Conroy R,Barry-Walsh C,Loftus B,Royston D,Leader M

更新日期：1994-05-01 00:00:00

abstract：AIMS:Studies in various cancer types have demonstrated discordance between results from different programmed death-ligand 1 (PD-L1) assays. Here, we compare the reproducibility and analytical concordance of four clinically developed assays for assessing PD-L1-positivity in tumour-infiltrating immune cells in the tumour...

journal_title：Histopathology

authors： Noske A,Ammann JU,Wagner DC,Denkert C,Lebeau A,Sinn P,Kreipe HH,Sommer U,Baretton G,Steiger K,Kiechle M,Hieke-Schulz S,Flores M,Roth W,Weichert W

更新日期：2020-09-16 00:00:00

abstract：AIMS:To assess the validity of grading in the Edinburgh Breast Conservation Series; a consecutive cohort of 1812 early breast cancer patients treated by breast conservation and radiotherapy between 1981 and 1998 in a single specialist centre with > or =9 years' follow-up and full staging data. METHODS AND RESULTS:A si...

journal_title：Histopathology

authors： Thomas JS,Kerr GR,Jack WJ,Campbell F,McKay L,Pedersen HC,Kunkler IH,Cameron DA,Chetty U,Bartlett JM

更新日期：2009-12-01 00:00:00

abstract：:The clinical and pathological features of three adnexal tumours of probable Wolffian origin are reported. One case was an incidental finding in a patient who died from ovarian carcinoma; in the other two cases the patients presented with lower abdominal pain. The three tumours were well-circumscribed, solid masses ari...

journal_title：Histopathology

authors： Rahilly MA,Williams AR,Krausz T,al Nafussi A

更新日期：1995-01-01 00:00:00

abstract：AIMS:Pulmonary artery (PA) dissection is a rare event which usually occurs in patients with underlying pulmonary hypertension. We describe two patients who developed PA dissection without pre-existing pulmonary hypertension and present an extensive review of the literature. METHODS AND RESULTS:In the first patient (a ...

journal_title：Histopathology

authors： Inayama Y,Nakatani Y,Kitamura H

更新日期：2001-05-01 00:00:00

abstract：AIMS:Previous studies have shown that increased vascularity is associated with tumour progression in human neuroblastoma (NB). The involvement of erythropoietin (Epo) in tumour angiogenesis has also been reported. The aim of this study was to correlate microvascular density and Epo/Epo-receptor (EpoR) expression in end...

journal_title：Histopathology

authors： Ribatti D,Poliani PL,Longo V,Mangieri D,Nico B,Vacca A

更新日期：2007-04-01 00:00:00

abstract：AIMS:MUC4 is a transmembrane glycoprotein that plays a role in cell growth signalling and is expressed in various epithelial tissues. Gene expression profiling and immunohistochemical analyses revealed that MUC4 is also constantly and specifically expressed in low-grade fibromyxoid sarcomas and sclerosing epithelioid f...

journal_title：Histopathology

authors： Matsuyama A,Jotatsu M,Uchihashi K,Tsuda Y,Shiba E,Haratake J,Hisaoka M

更新日期：2019-01-01 00:00:00

abstract：AIMS:Early recognition and accurate diagnosis underpins melanoma survival. Identifying early melanomas arising in association with pre-existing lesions is often challenging. Clinically suspicious foci, however small, must be identified and examined histologically. This study assessed the accuracy of punch biopsy 'scori...

journal_title：Histopathology

authors： Grogan J,Cooper CL,Dodds TJ,Guitera P,Menzies SW,Scolyer RA

更新日期：2018-01-01 00:00:00

abstract：AIMS:In addition to predominant granulocytic proliferation, bone marrow morphology in Philadelphia chromosome positive (Ph1+) CML is characterized by atypical dwarf or microforms of megakaryocytes. However, following therapy with interferon-alpha 2b (IFN), these micromegakaryocytes occur less frequently. The purpose of...

journal_title：Histopathology

authors： Thiele J,Schmitz B,Gross H,Kvasnicka HM,Niederle N,Leder LD,Fischer R

更新日期：1997-09-01 00:00:00

abstract：:The DNA content in gallbladder carcinoma and its relation to histological and cytological features was studied in 79 primary gallbladder carcinomas and 16 metastases. Abnormal DNA content was observed in 48 (51%) of 95 cases. In primary carcinomas, 44 (55.6%) showed a diploid DNA content, and 35 (44.4%) were aneuploid...

journal_title：Histopathology

authors： Roa I,Araya JC,Shiraishi T,Yatani R,Wistuba I,Villaseca M,De Aretxabala X

更新日期：1993-11-01 00:00:00

abstract：:The reactivity of a monoclonal anti-neutrophil elastase antibody (NP57) with routinely processed biopsy samples from various acute leukaemias has been examined and compared with that of chloroacetate esterase and CD15 (hapten X), two other myeloid cell-associated markers detectable in paraffin sections. No staining wa...

journal_title：Histopathology

authors： Ralfkiaer E,Pulford KA,Lauritzen AF,Avnstrøm S,Guldhammer B,Mason DY

更新日期：1989-06-01 00:00:00

abstract：:Surgical biopsy specimens from five children with cerebellar medulloblastoma were examined for ultrastructural evidence of differentiating activity. At light microscope level, all the tumour samples appeared primitive and featureless, and could not be classified as showing either neuroblastic or spongioblastic differe...

journal_title：Histopathology

authors： Moss TH

更新日期：1983-11-01 00:00:00

abstract：:Eight cases of myelosarcoma without acute leukaemia at time of diagnosis were reviewed and biopsies were immunostained using antibodies reacting with myeloid/monocytic markers. Initial tumour location included lymph nodes, paranasal sinuses, nasopharyngeal and/or orbital regions and other extranodal locations. Three c...

journal_title：Histopathology

authors： Furebring-Fredén M,Martinsson U,Sundström C

更新日期：1990-03-01 00:00:00

abstract：AIMS:Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis. Although seen commonly in our experience, the significance of histological thickening of the bile duct basement membrane on periodic acid Schiff (PAS)-p...

journal_title：Histopathology

authors： Colling R,Verrill C,Fryer E,Kartsonaki C,Wang LM,Chapman R,Rajabally N,Fleming K

更新日期：2016-05-01 00:00:00

abstract：AIMS:To examine how accurately immunohistochemical markers discriminate between pancreatobiliary and intestinal-type adenocarcinomas in the pancreatic head and to explore the prognostic importance of these markers among each of these histological types. METHODS AND RESULTS:Histopathological features of 114 consecutive...

journal_title：Histopathology

authors： Westgaard A,Schjølberg AR,Cvancarova M,Eide TJ,Clausen OP,Gladhaug IP

更新日期：2009-02-01 00:00:00

abstract：:Occasional biopsies of genital lesions due to chancroid, secondary syphilis (the condyloma latum) and granuloma inguinale are encountered in routine histopathological practice. These lesions have specific microscopical appearances enabling a confident, or at least a presumptive, diagnosis to be made in most cases, yet...

journal_title：Histopathology

authors： Freinkel AL

更新日期：1987-08-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:Monocarboxylate transporters (MCTs) have been considered promising targets for cancer therapy, since they facilitate lactate efflux in glycolytic tumours. However, their role in solid tumours is still poorly understood. Thus, the present work aimed to contribute to understanding the involvement of MCT1 and MCT4 in...

journal_title：Histopathology

authors： Pinheiro C,Albergaria A,Paredes J,Sousa B,Dufloth R,Vieira D,Schmitt F,Baltazar F

更新日期：2010-06-01 00:00:00

abstract：:To elucidate the role of cell turnover in primary gastric B-cell non-Hodgkin's lymphomas we studied tissue samples of 72 patients-26 small cell (25 MALT lymphomas) and 46 large cell (31 MALT lymphomas). Proliferation indices and apoptotic indices were measured by Mib-1 expression and terminal deoxynucleotidyltransfera...

journal_title：Histopathology

authors： Gisbertz IA,Schouten HC,Bot FJ,Arends JW

更新日期：1997-02-01 00:00:00

abstract：:Clinicopathological and immunohistological features of three cases of large cell lymphoma of bone are reported. On histological grounds, all the cases were diagnosed as histiocytic lymphomas (Rappaport) or primary centroblastic lymphomas, polymorphic subtype (Kiel). On immunophenotyping, malignant cells strongly react...

journal_title：Histopathology

authors： Falini B,Binazzi R,Pileri S,Mori A,Bertoni F,Canino S,Fagioli M,Minelli O,Ciani C,Pellicioli P

更新日期：1988-02-01 00:00:00

abstract：AIMS:Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is a downstream effector of Ras signalling, and is overexpressed in several types of human malignancy. However, its role in gastric cancer remains unclear. The aim of this study was to investigate the prognostic significance of G3BP1 in gastric can...

journal_title：Histopathology

authors： Min L,Ruan Y,Shen Z,Jia D,Wang X,Zhao J,Sun Y,Gu J

更新日期：2015-11-01 00:00:00

abstract：AIMS:Diffuse parenchymal lung diseases (DPLD) in children comprise a wide spectrum of rare disorders. In 2007 the Children's Interstitial Lung Disease (chILD) Research Cooperative proposed a classification system for DPLD in children <2 years of age. The aims of our study were to determine the utility and reproducibili...

journal_title：Histopathology

authors： Rice A,Tran-Dang MA,Bush A,Nicholson AG

更新日期：2013-12-01 00:00:00