Histological aspects of sexually transmitted genital lesions.

Abstract:

:Occasional biopsies of genital lesions due to chancroid, secondary syphilis (the condyloma latum) and granuloma inguinale are encountered in routine histopathological practice. These lesions have specific microscopical appearances enabling a confident, or at least a presumptive, diagnosis to be made in most cases, yet the value of biopsy in the diagnosis of these diseases is not generally appreciated. The ulcer of chancroid shows three zones--a narrow superficial zone of degenerate leucocytes and fibrin, a broader middle zone with characteristic vascular changes, and a deep zone in which there is a plasma cell and lymphocyte infiltrate. The condyloma latum shows hyperplasia of the epidermis which is infiltrated with polymorphonuclear leucocytes in addition to the mononuclear infiltration of the dermis. Large numbers of spirochaetes are found in the area of the polymorph exocytosis of the epidermis. The inflammatory infiltrate of granuloma inguinale consists of a neutrophil and plasma cell infiltrate with moderate numbers of large mononuclear cells in which there are one or more vacuoles containing Donovan bodies.

journal_name

Histopathology

journal_title

Histopathology

authors

Freinkel AL

doi

10.1111/j.1365-2559.1987.tb01885.x

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

819-31

issue

8

eissn

0309-0167

issn

1365-2559

journal_volume

11

pub_type

杂志文章
  • Epstein-Barr virus (EBV)-associated undifferentiated carcinoma of the parotid gland.

    abstract::A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1988.tb02075.x

    authors: Huang DP,Ng HK,Ho YH,Chan KM

    更新日期:1988-11-01 00:00:00

  • Expression of tenascin, type IV collagen and laminin during human intrahepatic bile duct development and in intrahepatic cholangiocarcinoma.

    abstract::Expression of tenascin, type IV collagen and laminin during human intrahepatic bile duct development and in cholangiocarcinoma was examined by immunohistochemistry. In the developing hilar bile ducts, tenascin was expressed in the mesenchyme around the epithelial cells migrating from the ductal plate into the mesenchy...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1994.tb01570.x

    authors: Terada T,Nakanuma Y

    更新日期:1994-08-01 00:00:00

  • Diversion colitis in children: an iatrogenic appendix vermiformis?

    abstract:AIMS:Diversion colitis (DC) is a localized, relatively benign, iatrogenic condition which occurs in almost 100% of diverted colonic segments in patients who undergo ileostomy/colostomy for various reasons. The aim of this study was to establish histological features of DC in children. METHODS AND RESULTS:Twenty-three ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2000.00803.x

    authors: Vujanić GM,Dojcinov SD

    更新日期:2000-01-01 00:00:00

  • Detailed analysis of the T-cell lymphocytic infiltrate in penile lichen sclerosus: an immunohistochemical and molecular investigation.

    abstract:AIM:To determine the extent of clonal outgrowth in the lymphocytic tissue infiltrate of lichen sclerosus (LS). The presence of T cells with a monoclonally rearranged T-cell receptor gamma-gene (TCRgamma) has been described in up to 50% of biopsies of vulvar and penile LS. MATERIAL AND RESULTS:We analysed 33 foreskin s...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2006.02406.x

    authors: Regauer S,Beham-Schmid C

    更新日期:2006-05-01 00:00:00

  • Recent advances in intestinal lymphomas.

    abstract::A large variety of lymphoma types may develop as primary intestinal neoplasms in the small intestines or, less often, in the colorectum. Among these are a few entities such as enteropathy-associated T-cell lymphoma or immunoproliferative small intestinal disease that, essentially, do not arise elsewhere than in the ga...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/his.12596

    authors: Foukas PG,de Leval L

    更新日期:2015-01-01 00:00:00

  • Elastosis in granular cell tumours: prevalence and distribution.

    abstract::Elastosis, a previously unreported feature, was found to be common in granular cell tumours. Twenty-four of 28 consecutive granular cell tumours were shown to display elastosis. The elastosis was found in three main sites: adventitial, interstitial and septal. Elastosis is statistically associated with the fibrosis pr...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1990.tb01057.x

    authors: McMahon JN,Rigby HS,Davies JD

    更新日期:1990-01-01 00:00:00

  • Lectin histochemistry of kidney tumours and its pathomorphological relevance.

    abstract::Thirty kidney tumours of various histological type were histochemically investigated under the light microscope by means of the ABC-method. We used four biotinylated lectins which are known to bind also to normal renal tubular epithelial cells of different nephron segments. The nuclear grade, the histological growth p...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1985.tb02783.x

    authors: Ulrich W,Horvat R,Krisch K

    更新日期:1985-10-01 00:00:00

  • Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective.

    abstract::Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease is critical to early intervention or prevention. This review addresses six important variables, including...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2559.2007.02938.x

    authors: Jarboe EA,Folkins AK,Drapkin R,Ince TA,Agoston ES,Crum CP

    更新日期:2008-08-01 00:00:00

  • Gastrointestinal lymphoproliferative disorders.

    abstract::Malignant lymphomas can be first detected in some patients in endoscopic biopsies of the gastrointestinal (GI) tract. However, their recognition and accurate classification often pose problems for the pathologist for several reasons. First, the small sampling size limits pattern recognition and the number of ancillary...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2559.2006.02571.x

    authors: Banks PM

    更新日期:2007-01-01 00:00:00

  • Why do histology on retinal haemorrhages in suspected non-accidental injury?

    abstract::The detailed documentation of ocular pathology has become an important component in the autopsy investigation of suspected cases of non-accidental injury in infants and young children. Careful histological examination of retinal haemorrhages is of critical importance, but there remains debate about the significance of...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2003.01762.x

    authors: Gilliland MG,Luthert P

    更新日期:2003-12-01 00:00:00

  • Bcl-10 protein highly correlates with the expression of phosphorylated p65 NF-kappaB in peripheral T-cell lymphomas and is associated with clinical outcome.

    abstract:AIMS:In T cells, protein kinase C (PKC) theta plays a major role in T-cell receptor (TCR)-mediated activation of a novel nuclear factor (NF)-kappaB pathway that involves phosphorylation of p65 at serine 536 (Pp65(Ser536)). Bcl-10 acts along the same pathway downstream of PKC theta to activate NF-kappaB. The aim was to ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2009.03250.x

    authors: Briones J,Moga E,Espinosa I,Vergara C,Alvarez E,Villa J,Bordes R,Delgado J,Prat J,Sierra J

    更新日期:2009-03-01 00:00:00

  • Immunohistochemical expression patterns of AP2alpha and AP2gamma in the developing fetal human breast.

    abstract:AIMS:AP2alpha (TFAP2A) and AP2gamma (TFAP2G) transcription factors have been implicated in the control of proliferation, differentiation and apoptosis of normal breast epithelium and in breast cancer. The aim of this study was to provide a comprehensive analysis of the expression patterns of TFAP2A and TFAP2G in the de...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2007.02887.x

    authors: Friedrichs N,Steiner S,Buettner R,Knoepfle G

    更新日期:2007-12-01 00:00:00

  • A method to fix lipids for staining fat embolism in paraffin sections.

    abstract:AIMS:To develop a method to preserve lipids in formalin-fixed tissues for staining in paraffin sections, and to illustrate its use in lung and brain of a fat embolism case, and in examples of fatty liver and atheroma. METHODS AND RESULTS:A saturated solution of linoleic acid in 70% ethylene glycol was prepared and tis...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2002.01414.x

    authors: Tracy RE,Walia P

    更新日期:2002-07-01 00:00:00

  • Histopathological study of lymph node lesions in the acute phase of Kawasaki disease.

    abstract:AIMS:  To review the histopathological features of cervical LNs, and to clarify the changes in extracervical LNs, in acute Kawasaki disease (KD). METHODS AND RESULTS:  The samples were obtained from 33 patients with acute-phase KD. We divided the LNs into those in the neck (n = 23) and those located elsewhere (n = 26)...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12007

    authors: Yokouchi Y,Oharaseki T,Harada M,Ihara F,Naoe S,Takahashi K

    更新日期:2013-02-01 00:00:00

  • The origin of cells in the glomerular crescent investigated by the use of monoclonal antibodies.

    abstract::A study was made of the cells forming the crescents in human crescentic glomerulonephritis. The investigation was performed using a panel of antibodies with immunoperoxidase techniques in formalin fixed, paraffin embedded renal biopsy material. Some of the cells of glomerular crescents were found to contain cytokerati...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1986.tb02592.x

    authors: Harrison DJ,MacDonald MK

    更新日期:1986-09-01 00:00:00

  • Adrenal lipoma: a rare tumour of the adrenal gland.

    abstract::We report a case of an adrenal lipoma, a very rare lesion first described in 1899 and of which a total of six cases have previously been reported (Lange 1966, Page, De Lellis & Hough 1986). Five of these cases were found incidentally at post mortem. In one case an acute hypertensive episode intra-operatively simulated...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1989.tb03067.x

    authors: Avinoach I,Robinson CR,Avinoah E,Peiser J

    更新日期:1989-08-01 00:00:00

  • Warthin-like tumour of the thyroid gland: RET/PTC expression indicates it is a variant of papillary carcinoma.

    abstract:AIMS:Three cases with features of so-called 'Warthin-like tumour' of the thyroid (WaLTT) are described, in order to evaluate its relationship with papillary carcinoma (PC). METHODS AND RESULTS:We performed an histological and immunohistochemical study with emphasis on RET/PTC expression. The most striking features are...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2000.00925.x

    authors: D'Antonio A,De Chiara A,Santoro M,Chiappetta G,Losito NS

    更新日期:2000-06-01 00:00:00

  • Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma.

    abstract:AIMS:Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in gallbladder tissues. I...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.13797

    authors: Espinoza JA,Riquelme I,Sagredo EA,Rosa L,García P,Bizama C,Apud-Bell M,Leal P,Weber H,Benavente F,Vargas S,Romero D,Kalergis AM,Roa JC

    更新日期:2019-03-01 00:00:00

  • Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.

    abstract:AIMS:Genome-wide next-generation sequencing has revealed several driver mutations and has allowed the establishment of a molecular taxonomy of gastric cancer. However, there are few detailed studies on the mutational spectrum of poorly cohesive gastric carcinoma. Thus, this study aim to investigate its mutation profile...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.13383

    authors: Kwon CH,Kim YK,Lee S,Kim A,Park HJ,Choi Y,Won YJ,Park DY,Lauwers GY

    更新日期:2018-03-01 00:00:00

  • Loss of special AT-rich sequence-binding protein 1 (SATB1) predicts poor survival in patients with colorectal cancer.

    abstract:AIM:Special AT-rich sequence-binding protein 1 (SATB1) is a cell type-specific matrix attachment region binding protein, functioning as a global genome organizer. This study aims to investigate the expression pattern and the prognostic value of SATB1 in colorectal cancer. METHODS AND RESULTS:Prospectively collected da...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12295

    authors: Al-Sohaily S,Henderson C,Selinger C,Pangon L,Segelov E,Kohonen-Corish MR,Warusavitarne J

    更新日期:2014-08-01 00:00:00

  • Counts of S-100 positive epidermal dendritic cells in Kveim test skin biopsies.

    abstract::S-100 positive epidermal dendritic cells were counted in skin biopsies from 48 Kveim tests and four known foreign-body reactions. Counts in histologically positive Kveim biopsies (mean 11.3 per 200 basal cells) were significantly higher than in either negative biopsies (5.1; P less than 0.001) or foreign-body reaction...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1991.tb01457.x

    authors: Shaw PA,Fletcher A

    更新日期:1991-02-01 00:00:00

  • A cytokeratin immunohistochemical study of cholestatic liver disease: evidence that hepatocytes can express 'bile duct-type' cytokeratins.

    abstract::A cytokeratin immunohistochemical study was performed on 38 liver biopsies from cases of primary biliary cirrhosis, primary sclerosing cholangitis, extrahepatic biliary obstruction or drug-induced liver disease in order to analyse the cytoskeletal changes in detail. On paraffin sections of 27 cases, a variable number ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1989.tb03060.x

    authors: Van Eyken P,Sciot R,Desmet VJ

    更新日期:1989-08-01 00:00:00

  • Pleuroparenchymal fibroelastosis and non-specific interstitial pneumonia: frequent pulmonary sequelae of haematopoietic stem cell transplantation.

    abstract:AIMS:Pulmonary sequelae, reported as chronic graft-versus-host disease (cGVHD), of haematopoietic stem cell transplantation (HSCT) include constrictive bronchiolitis obliterans (CBO), lymphocytic bronchiolitis (LB), and veno-occlusive disease (VOD); recently, pleuroparenchymal fibroelastosis (PPFE) has also been descri...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12553

    authors: Takeuchi Y,Miyagawa-Hayashino A,Chen F,Kubo T,Handa T,Date H,Haga H

    更新日期:2015-03-01 00:00:00

  • Simple mucin-type carbohydrate antigens (T, Tn and sialosyl-Tn) in mucoepidermoid carcinoma of the salivary glands.

    abstract::Thirty-two cases of mucoepidermoid carcinoma of the salivary glands were studied in order to characterize the expression of simple mucin-type carbohydrate antigens T, Tn and sialosyl-Tn and to evaluate its implication for tumour histogenesis. Monoclonal antibodies of known specificity were used on formalin-fixed, para...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1994.tb01372.x

    authors: Fonseca I,Costa Rosa J,Félix A,Therkildsen MH,Mandel U,Soares J

    更新日期:1994-12-01 00:00:00

  • Does nodular lymphocyte predominant Hodgkin's disease arise from progressively transformed germinal centres? A case report with an unusually prolonged history.

    abstract::A case is reported of nodular lymphocyte predominant Hodgkin's disease arising 13 years after the removal of a lymph node from the same site which showed marked progressive transformation of germinal centres. The morphological evidence for a histogenetic relationship between the two conditions is presented and discuss...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1987.tb02672.x

    authors: Crossley B,Heryet A,Gatter KC

    更新日期:1987-06-01 00:00:00

  • Characterization of the inflammatory infiltrate in ovarian dysgerminoma: an immunocytochemical study.

    abstract::The inflammatory infiltrate has been characterized in 10 cases of ovarian dysgerminoma using a panel of antisera to T-cells, B-cells and macrophages. The expression of Class II major histocompatibility complex (MHC) antigens and the distribution of interferons alpha and gamma were also examined. T-lymphocytes were pre...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1992.tb01033.x

    authors: Stewart CJ,Farquharson MA,Foulis AK

    更新日期:1992-06-01 00:00:00

  • Coexpression of hypoxia-inducible factor-1α and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients.

    abstract:AIMS:To study whether coexpression of the two hypoxia-related proteins hypoxia-inducible factor (HIF)-1α and glucose transporter (GLUT)-1 has prognostic relevance in oral squamous cell carcinomas (OSCCs). METHODS AND RESULTS:Eighty-two OSCC samples were analysed for expression levels of HIF-1α and GLUT-1 by immunohist...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.03806.x

    authors: Eckert AW,Lautner MH,Schütze A,Taubert H,Schubert J,Bilkenroth U

    更新日期:2011-06-01 00:00:00

  • Association of breast carcinoma and multiple intraductal papillomas: an histological and immunohistochemical investigation.

    abstract::To identify histological preneoplastic lesions and early neoplastic foci, a histological and immunohistochemical study has been conducted on a series of 18 cases with the rare association of multiple intraductal papillomas and in situ breast carcinoma. The pathological and clinical data of these cases have been collat...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1984.tb02414.x

    authors: Papotti M,Gugliotta P,Ghiringhello B,Bussolati G

    更新日期:1984-11-01 00:00:00

  • Modes of Helicobacter colonization and gastric epithelial damage.

    abstract::A total of 144 gastric biopsies colonized by Helicobacter-like organisms were studied under light and differential interference contrast microscopy for the modes of bacterial colonization. Biopsies were also graded for the degree of epithelial damage (epithelial-damage-grade: 0 to 6, in ascending order of severity) an...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1992.tb00439.x

    authors: Chan WY,Hui PK,Leung KM,Thomas TM

    更新日期:1992-12-01 00:00:00

  • Immunoglobulin-containing cells in liver biopsies of patients with chronic hepatitis and primary biliary cirrhosis.

    abstract::The numbers of IgA, IgM and IgG-containing cells were studied by means of an indirect immunoperoxidase technique and morphometry in liver biopsies of patients with primary biliary cirrhosis and chronic hepatitis, in whom serum immunoglobulin concentrations were also determined. In patients with primary biliary cirrhos...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1984.tb02368.x

    authors: Van Spreeuwel JP,Van Gorp LH,Nadorp JH,Janssens AR,Lindeman J,Meijer CJ

    更新日期:1984-07-01 00:00:00