Lectin histochemistry of kidney tumours and its pathomorphological relevance.

abstract：:A total of 118 biopsies from 20 different types of benign, malignant and reactive vascular proliferations were examined for the expression of the CD30 antigen using the monoclonal antibodies BerH2 and HRS4 on paraffin-embedded sections. The results were compared with those obtained using an antibody directed against t...

journal_title：Histopathology

authors： Rudolph P,Lappe T,Schmidt D

更新日期：1993-08-01 00:00:00

abstract：AIMS:Extraskeletal myxoid chondrosarcoma is a rare low-grade soft-tissue sarcoma with locally aggressive and metastasizing potential. Extraskeletal myxoid chondrosarcoma has distinctive clinical, light microscopic, immunophenotypic, cytogenetic and ultrastructural features. Evidence that extraskeletal myxoid chondrosar...

journal_title：Histopathology

authors： Goh YW,Spagnolo DV,Platten M,Caterina P,Fisher C,Oliveira AM,Nascimento AG

更新日期：2001-11-01 00:00:00

abstract：:Four cases of endocrine neoplasia within fibroadenomas of the breast are described. The tumours are identifiable by light microscopic, silver impregnation and ultrastructural studies. Argyrophilia and the presence of dense-core granules establish the identity of this tumour type. The differential diagnosis from, and p...

journal_title：Histopathology

authors： Eusebi V,Azzopardi JG

更新日期：1980-07-01 00:00:00

abstract：:The numbers of IgA, IgM and IgG-containing cells were studied by means of an indirect immunoperoxidase technique and morphometry in liver biopsies of patients with primary biliary cirrhosis and chronic hepatitis, in whom serum immunoglobulin concentrations were also determined. In patients with primary biliary cirrhos...

journal_title：Histopathology

authors： Van Spreeuwel JP,Van Gorp LH,Nadorp JH,Janssens AR,Lindeman J,Meijer CJ

更新日期：1984-07-01 00:00:00

abstract：:Anaplastic choroid plexus carcinoma is a tumour with a predilection for the posterior fossa of infants and can be difficult to distinguish histologically from medulloblastoma without the aid of immunocytochemistry using a panel of antibodies. Of a series of 17 choroid plexus carcinomas (five of which were classed as m...

journal_title：Histopathology

authors： Newbould MJ,Kelsey AM,Arango JC,Ironside JW,Birch J

更新日期：1995-02-01 00:00:00

abstract：AIMS:Neuropilin-2 is a coreceptor for vascular endothelial growth factor family members. Blockade of neuropilin-2 is able to suppress lymphogenous metastasis in preclinical models. The aim of this study was to validate a protocol for the evaluation of neuropilin-2 protein expression in situ, by comparison with in-situ ...

journal_title：Histopathology

authors： Jubb AM,Sa SM,Ratti N,Strickland LA,Schmidt M,Callahan CA,Koeppen H

更新日期：2012-09-01 00:00:00

abstract：:A series of 10 sweat-gland carcinomas is reported. The ages of the patients at presentation ranged from 12 to 79 years. Three of the tumours had shown long latent periods with a mass present for up to 20 years. Prognosis proved to be related to the histological subtype. Thus, two papillary syringocystadeno-carcinomas,...

journal_title：Histopathology

authors： Dissanayake RV,Salm R

更新日期：1980-07-01 00:00:00

abstract：:Three cases of gastric parietal cell carcinoma are described. Tumour cells are round to polygonal, with abundant eosinophilic, granular cytoplasm reactive with phosphotungstic acid haematoxylin and Luxol Fast Blue. Ultrastructurally the tumour cells are characterized by abundant mitochondria, tubulovesicles, intracell...

journal_title：Histopathology

authors： Capella C,Frigerio B,Cornaggia M,Solcia E,Pinzon-Trujillo Y,Chejfec G

更新日期：1984-09-01 00:00:00

abstract：:We report an example of what we believe to be an adenocarcinoma of the appendix testis. This very rare neoplasm arose in a patient on long term treatment with oestrogens which may be implicated as an aetiological factor. ...

journal_title：Histopathology

authors： Kernohan NM,Coutts AG,Best PV

更新日期：1990-08-01 00:00:00

abstract：AIMS:Hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome is caused by germline mutations in the Fumarate hydratase (FH) gene. In young women, the syndrome often presents with symptomatic uterine leiomyomas, leading to myomectomy or hysterectomy. In this study, we aimed to investigate the incidence and muta...

journal_title：Histopathology

authors： Liu C,Dillon J,Beavis AL,Liu Y,Lombardo K,Fader AN,Hung CF,Wu TC,Vang R,Garcia JE,Xing D

更新日期：2020-02-01 00:00:00

abstract：AIMS:Angiogenesis is essential for tumour growth and metastasis and tumour necrosis factor (TNF)-alpha is a potent angiogenic factor. Invasive micropapillary carcinoma of the breast (IMPC), a rare subtype of breast cancer, possesses a lymphotropic nature with a high incidence of lymph node metastasis and poor prognosis...

journal_title：Histopathology

authors： Cui LF,Guo XJ,Wei J,Liu FF,Fan Y,Lang RG,Gu F,Zhang XM,Fu L

更新日期：2008-10-01 00:00:00

abstract：:Intra-abdominal panniculitis is a tumour-like inflammatory condition of adipose tissue. The aetiology and pathogenesis of the disease is unknown, but a number of associated diseases have been recorded. It has been customary to deal with only primary cases in the literature. This study was undertaken in order to descri...

journal_title：Histopathology

authors： Bak M

更新日期：1996-07-01 00:00:00

abstract：AIMS:To determine the expression of matrix metalloproteinases (MMPs)-2, -7 and -9 and beta-catenin in uterine serous carcinoma (USC) and endometrioid endometrial carcinoma (EEC) and to investigate any difference in expression between EEC and USC which might explain the mechanism of invasion and aggressive behaviour of ...

journal_title：Histopathology

authors： Monaghan H,MacWhinnie N,Williams AR

更新日期：2007-02-01 00:00:00

abstract：AIMS:To determine the frequency of point mutation in c-kit in CD117+ small cell lung cancer (SCLC). A significant proportion of SCLCs have been documented to be CD117+, thereby signifying they express the c-kit gene product. This finding suggests this tumour may be a potential target for tyrosine kinase inhibitor (TKI)...

journal_title：Histopathology

authors： Mojica WD,Saxena R,Starostik P,Cheney RT

更新日期：2005-11-01 00:00:00

abstract：AIMS:To analyse the expression of alphavbeta6, an epithelial integrin involved in wound healing and tumorigenesis, in various human carcinoma types. METHODS AND RESULTS:A new monoclonal antibody to the human beta6 subunit, 5C4, was used to locate alphavbeta6 in 157 cancers of gastroenteropancreatic and 21 of lung orig...

journal_title：Histopathology

authors： Sipos B,Hahn D,Carceller A,Piulats J,Hedderich J,Kalthoff H,Goodman SL,Kosmahl M,Klöppel G

更新日期：2004-09-01 00:00:00

abstract：:We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti-Leu-7, while th...

journal_title：Histopathology

authors： Allegranza A,Pileri S,Frank G,Ferracini R

更新日期：1990-11-01 00:00:00

abstract：:The expression of cytokeratin intermediate filaments by a tumour has been accepted as evidence of an epithelial origin. Although there have been anecdotal reports of cytokeratin expression within tissues and neoplasms of non-epithelial origin, particularly muscle, there have been no comprehensive studies of its freque...

journal_title：Histopathology

authors： Brown DC,Theaker JM,Banks PM,Gatter KC,Mason DY

更新日期：1987-05-01 00:00:00

abstract：AIMS:More than 50% of neuroblastomas (NBs) present with haematogenous and/or lymphatic metastasis; however, little is known about the clinicopathological significance in NBs of the key lymphangiogenesis growth factors vascular endothelial growth factor (VEGF)-C and VEGF-D and the receptor VEGFR-3. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Ramani P,Nash R,Radevsky L,Patel A,Luckett M,Rogers C

更新日期：2012-12-01 00:00:00

abstract：:The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cel...

journal_title：Histopathology

authors： El-Labban NG,Lee KW

更新日期：1983-11-01 00:00:00

abstract：:We reviewed 45 pulmonary B-cell non-Hodgkin's lymphomas to determine whether their morphology and immunohistochemical features were those of lymphomas arising from mucosa-associated lymphoid tissue (MALT), as described in other sites. The polymerase chain reaction was used to provide further information on clonality. ...

journal_title：Histopathology

authors： Nicholson AG,Wotherspoon AC,Diss TC,Butcher DN,Sheppard MN,Isaacson PG,Corrin B

更新日期：1995-05-01 00:00:00

abstract：AIMS:Tumour-infiltrating lymphocytes (TILs) are prognostic in invasive breast cancer; however, their prognostic significance in ductal carcinoma in situ (DCIS) has not been established. The Oncotype DX (ODX) Breast DCIS Score test is a genomic assay used to predict the local recurrence risk. The aims of this study were...

journal_title：Histopathology

authors： Komforti M,Badve SS,Harmon B,Lo Y,Fineberg S

更新日期：2020-11-01 00:00:00

abstract：AIMS:Pathological or neuroprotective mechanisms in the brain in severe malaria may arise from microvascular obstruction with malaria-parasitized erythrocytes. This study aimed to investigate the role of hypoxia and induction of the vascular endothelial growth factor (VEGF) pathway in the neuropathophysiology of severe ...

journal_title：Histopathology

authors： Medana IM,Day NP,Roberts R,Sachanonta N,Turley H,Pongponratn E,Hien TT,White NJ,Turner GD

更新日期：2010-08-01 00:00:00

abstract：:We report a case of oesophageal carcinosarcoma with prominent rhabdomyoblastic differentiation. Immunohistochemically, the rhabdomyblasts were mainly reactive to vimentin, cytokeratin, desmin, muscle-specific actin, myosin, and myoglobin, and were surrounded by laminin and type IV collagen-positive basement membranes....

journal_title：Histopathology

authors： Guarino M,Reale D,Micoli G,Forloni B

更新日期：1993-05-01 00:00:00

abstract：AIMS:Macrophage colony-stimulating factor (M-CSF) binds to colony-stimulating factor-1 receptor (CSF-1R) and stimulates proliferation and differentiation of monocytes, macrophages and their bone marrow progenitors. M-CSF, CSF-1R, the macrophage marker CD68, and the pan T-lymphocyte marker CD3 are increased in many huma...

journal_title：Histopathology

authors： Richardsen E,Uglehus RD,Due J,Busch C,Busund LT

更新日期：2008-07-01 00:00:00

abstract：AIMS:Intestinal metaplasia (IM) has been implicated in the pathogenesis of gastro-oesophageal carcinoma, but because of its common occurrence, its specificity for use in cancer surveillance is low. IM subtypes characterized by mucin phenotype have been studied to try and improve specificity. METHODS AND RESULTS:On bal...

journal_title：Histopathology

authors： Shah KA,Deacon AJ,Dunscombe P,Price AB

更新日期：1997-09-01 00:00:00

abstract：AIMS:Calretinin, a calcium-binding protein, is expressed primarily in certain subtypes of neurons. It has also been reported to be present in mesotheliomas and other tumours. The aim was to determine the expression of calretinin in selected odontogenic neoplasms. METHODS AND RESULTS:Immunohistochemistry for calretinin...

journal_title：Histopathology

authors： Alaeddini M,Etemad-Moghadam S,Baghaii F

更新日期：2008-02-01 00:00:00

abstract：:The paper reports a re-evaluation--based on the Kiel classification for non-Hodgkin lymphomas--of a group of cases initially diagnosed as undifferentiated small cell carcinomas or primary lymphomas of the thyroid. Twelve such cases were found among the 155 cases of primary malignant tumours of the thyroid recorded at ...

journal_title：Histopathology

authors： Heimann R,Vannineuse A,De Sloover C,Dor P

更新日期：1978-05-01 00:00:00

abstract：AIMS:Rheumatoid arthritis (RA) and pigmented villonodular synovitis (PVNS) are aggressive diseases with progressive joint destruction. The present study aims to define cell cycle phases, polyploidy and the immunophenotype of proliferating synovial cells in both diseases. METHODS AND RESULTS:Synovial tissues from patie...

journal_title：Histopathology

authors： Berger I,Weckauf H,Helmchen B,Ehemann V,Penzel R,Fink B,Bernd L,Autschbach F

更新日期：2005-05-01 00:00:00

abstract：:A review of 76 endomyocardial biopsies and 54 autopsies of patients with dilated cardiomyopathy (DCM) revealed features of hypertrophy and degenerative changes associated with long-standing hypertrophy. Long-term survivors had significantly heavier heart weights. Short-term survivors had heavier than normal right vent...

journal_title：Histopathology

authors： Rose AG,Beck W

更新日期：1985-04-01 00:00:00

abstract：AIMS:We investigated the phenotypic and cytotoxic characteristics of different types of peripheral T-cell and NK-cell lymphomas and correlated the findings of cytotoxic phenotype with Epstein-Barr virus (EBV) association. METHODS AND RESULTS:Eighty cases of peripheral T-cell and NK-cell lymphomas, classified according...

journal_title：Histopathology

authors： Chan AC,Ho JW,Chiang AK,Srivastava G

更新日期：1999-01-01 00:00:00