Lobular endocrine neoplasia in fibroadenoma of the breast.

abstract：:We report a primary non-Hodgkin's B-cell lymphoma of the urethra in a 78-year-old female. Serum antibodies for Epstein-Barr virus (EBV) were negative, but there was a 40-fold increase in antibodies to EBV-associated nuclear antigen. Using PCR and in situ hybridization techniques, EBV genome was found in the tumour cel...

journal_title：Histopathology

authors： Ohsawa M,Mishima K,Suzuki A,Hagino K,Doi J,Aozasa K

更新日期：1994-06-01 00:00:00

abstract：AIM:Although the World Health Organization (WHO) histological criteria distinguishing benign from atypical and malignant meningioma are clear, discerning benign from atypical meningioma is still somewhat difficult, leading to interobserver diagnostic variability. Osteopontin (OPN) and cortactin play important roles in ...

journal_title：Histopathology

authors： Lin CK,Tsai WC,Lin YC,Hueng DY

更新日期：2012-01-01 00:00:00

abstract：:In the course of running two clinical trials between 1966 and 1985, data became available for 1315 patients, 713 in the first trial and 602 patients in the second trial, which has allowed comparison between histological findings in laryngeal and hypopharyngeal carcinoma, the observed survival and the tumour-free rates...

journal_title：Histopathology

authors： Wiernik G,Millard PR,Haybittle JL

更新日期：1991-11-01 00:00:00

abstract：AIMS:The differential diagnosis of benign hepatic lesions and well-differentiated hepatocellular carcinomas can be a challenge, especially in small biopsy specimens. Recently, novel proteins expressed by the neovasculature in hepatocellular carcinoma (HCC) have been identified. The aim of this study was to compare the ...

journal_title：Histopathology

authors： Heukamp LC,Fischer HP,Schirmacher P,Chen X,Breuhahn K,Nicolay C,Büttner R,Gütgemann I

更新日期：2006-09-01 00:00:00

abstract：AIMS:To investigate whether Glia maturation factor-beta (GMFB) is expressed in thymomas and is associated with T-cell development. METHODS AND RESULTS:We investigated the expression of GMFB by immunohistochemistry in 86 cases of thymoma classified into five type A, 35 type AB, 11 type B1, 26 type B2, and nine type B3 ...

journal_title：Histopathology

authors： Yamazaki H,Tateyama H,Asai K,Fukai I,Fujii Y,Tada T,Eimoto T

更新日期：2005-09-01 00:00:00

abstract：:We studied kidney sections from 15 cases of polyarteritis using an immunocytochemical technique to demonstrate cells containing immunoreactive renin. Ten cases of classical polyarteritis nodosa showed hyperplasia of renin-containing cells in areas of renal cortex with histological evidence of ischaemia--appearances in...

journal_title：Histopathology

authors： Graham PC,Lindop GB

更新日期：1990-04-01 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a member of the lipocalin superfamily. Although its overexpression in various cancers has been reported, little is known about its expression and clinical significance in oral squamous cell carcinoma (OSCC). This study aimed to elucidate the clinical significanc...

journal_title：Histopathology

authors： Shinriki S,Jono H,Ueda M,Obayashi K,Nakamura T,Ota K,Ota T,Sueyoshi T,Guo J,Hayashi M,Hiraki A,Nakayama H,Yamashita S,Shinohara M,Ando Y

更新日期：2014-02-01 00:00:00

abstract：:Cancer biomarkers provide an opportunity to diagnose tumours earlier and with greater accuracy. They can also identify those patients most at risk of disease recurrence and predict which tumours will respond to different therapeutic approaches. Such biomarkers will be especially useful in the diagnosis and management ...

journal_title：Histopathology

authors： Proctor I,Stoeber K,Williams GH

更新日期：2010-07-01 00:00:00

abstract：:Fifteen hamartomas of the breast have been studied by dissecting microscopy of thick sections at a depth of 1.0 to 2.5 mm, and by conventional 5 microns deep sections. This combined approach has revealed six distinctive features, three in the parenchymal structure and three in the connective tissue components. Ducts (...

journal_title：Histopathology

authors： Davies JD,Kulka J,Mumford AD,Armstrong JS,Wells CA

更新日期：1994-02-01 00:00:00

abstract：AIMS:To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients. METHODS AND RESULTS:Immunostaining was analysed on a total of 192 biopsy samples of 22 Barrett's patients with no dysplasia...

journal_title：Histopathology

authors： van de Winkel A,van Zoest KP,van Dekken H,Moons LM,Kuipers EJ,van der Laan LJ

更新日期：2011-01-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：:The post-transplant lymphoproliferative disorders represent a spectrum of life-threatening, generally Epstein-Barr virus-associated lymphoid proliferations which occur in the setting of exogenous immunosuppression following organ transplantation. Histopathological, phenotypic, genotypic and Epstein-Barr virus studies ...

journal_title：Histopathology

authors： Swerdlow SH

更新日期：1992-05-01 00:00:00

abstract：:HLA-DR expression was examined in 50 consecutive primary cutaneous malignant melanomas with a Breslow depth greater than 2 mm using two well-characterized monoclonal antibodies which detect fixation-resistant epitopes. In 31 of these cases (62%) a subpopulation of tumour cells was reactive, although there was consider...

journal_title：Histopathology

authors： Colloby PS,West KP,Fletcher A

更新日期：1992-05-01 00:00:00

abstract：AIMS:The aims of this study were to define whether diffuse cutaneous reticulohistiocytosis could be underpinned by somatic genetic alterations and represent a precursor of more aggressive forms of disease. METHODS AND RESULTS:A 59-year-old man with diffuse cutaneous reticulohistiocytosis experienced bone marrow locali...

journal_title：Histopathology

authors： Fusco N,Bonometti A,Augello C,Fabris S,Boiocchi L,Fiori S,Morotti D,Fracchiolla N,Berti E,Gianelli U

更新日期：2017-05-01 00:00:00

abstract：:Liver biopsy challenge and clinicopathological correlation Liver biopsy interpretation in inflammatory diseases of the bile ducts or chronic cholangiopathies may be challenging, especially for pathologists working outside referral centres, where there is a limited exposure to relatively uncommon conditions. In view of...

journal_title：Histopathology

authors： Portmann B,Zen Y

更新日期：2012-01-01 00:00:00

abstract：AIMS:Three cases with features of so-called 'Warthin-like tumour' of the thyroid (WaLTT) are described, in order to evaluate its relationship with papillary carcinoma (PC). METHODS AND RESULTS:We performed an histological and immunohistochemical study with emphasis on RET/PTC expression. The most striking features are...

journal_title：Histopathology

authors： D'Antonio A,De Chiara A,Santoro M,Chiappetta G,Losito NS

更新日期：2000-06-01 00:00:00

abstract：AIMS:It is still not clear whether oval cells demonstrate diverse morphology, immunophenotype or quantity in different human liver diseases. The aim of this study was to investigate these differences in hepatitis B virus (HBV)-positive and hepatitis C virus (HCV)-positive human liver cirrhosis (HLC). METHODS AND RESUL...

journal_title：Histopathology

authors： Sun C,Jin XL,Xiao JC

更新日期：2006-04-01 00:00:00

abstract：AIM:To determine the inter-observer variation in the histological diagnosis of colorectal polyps. METHODS AND RESULTS:Four hundred and forty polyps were randomly selected from a colorectal cancer screening programme. Polyps were first evaluated by a general (324 polyps) or expert (116 polyps) pathologist, and subseque...

journal_title：Histopathology

authors： van Putten PG,Hol L,van Dekken H,Han van Krieken J,van Ballegooijen M,Kuipers EJ,van Leerdam ME

更新日期：2011-05-01 00:00:00

abstract：AIMS:Genome-wide next-generation sequencing has revealed several driver mutations and has allowed the establishment of a molecular taxonomy of gastric cancer. However, there are few detailed studies on the mutational spectrum of poorly cohesive gastric carcinoma. Thus, this study aim to investigate its mutation profile...

journal_title：Histopathology

authors： Kwon CH,Kim YK,Lee S,Kim A,Park HJ,Choi Y,Won YJ,Park DY,Lauwers GY

更新日期：2018-03-01 00:00:00

abstract：AIMS:Calretinin, a calcium-binding protein, is expressed primarily in certain subtypes of neurons. It has also been reported to be present in mesotheliomas and other tumours. The aim was to determine the expression of calretinin in selected odontogenic neoplasms. METHODS AND RESULTS:Immunohistochemistry for calretinin...

journal_title：Histopathology

authors： Alaeddini M,Etemad-Moghadam S,Baghaii F

更新日期：2008-02-01 00:00:00

abstract：AIMS:Prognostic factors affecting survival in cases of leiomyosarcoma of soft parts were investigated in this study. METHODS AND RESULTS:A retrospective study of 267 patients was carried out. This group comprised 142 females (53%) and 125 males (47%), whose ages ranged from 7 to 95 years (median 58 years). One hundred...

journal_title：Histopathology

authors： Miyajima K,Oda Y,Oshiro Y,Tamiya S,Kinukawa N,Masuda K,Tsuneyoshi M

更新日期：2002-04-01 00:00:00

abstract：AIMS:Angiogenesis is an important factor in tumour growth and metastasis. Vascular endothelial growth factor receptor 2 (VEGFR-2) or KDR plays a crucial role in angiogenesis. The aim of this study was to raise and characterize antibodies against phosphorylated KDR which could be used for studies on human tissues to ass...

journal_title：Histopathology

authors： Stewart M,Turley H,Cook N,Pezzella F,Pillai G,Ogilvie D,Cartlidge S,Paterson D,Copley C,Kendrew J,Barnes C,Harris AL,Gatter KC

更新日期：2003-07-01 00:00:00

abstract：:Some antigenic determinants can be preserved in tissues after plastic embedding. In the present study liver tissue was fixed with glutaraldehyde or paraformaldehyde, dehydrated with ethanol and toluene and embedded in araldite which was then polymerized at 37 degrees C. Immunofluorescence was performed on semi-thin se...

journal_title：Histopathology

authors： Scotto J

更新日期：1977-09-01 00:00:00

abstract：:Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, incl...

journal_title：Histopathology

authors： Johnston PW,Fioratou E,Flin R

更新日期：2011-09-01 00:00:00

abstract：AIMS:To look for FOXL2 mutation in rare ovarian epithelial lesions showing stromal components with morphological features of adult granulosa cell tumour (AGCT). METHODS AND RESULTS:We report the 402C→G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations tha...

journal_title：Histopathology

authors： Singh N,Gilks CB,Huntsman DG,Smith JH,Coutts M,Ganesan R,McCluggage WG

更新日期：2014-04-01 00:00:00

abstract：:Therapeutic use of oestrogens by males with carcinoma of the prostate leads to testicular atrophy with markedly reduced spermatogenesis after only 21 d (Oshima et al. 1974). Treatment for over a year results in paucity of germ cells, vacuolation of Sertoli cells and reduction in Leydig cells (Lu & Steinberger 1978, Sm...

journal_title：Histopathology

authors： Venizelos ID,Paradinas FJ

更新日期：1988-04-01 00:00:00

abstract：AIM:Achalasia is a disease of the oesophagus characterized by increased lower oesophageal sphincter (LOS) tone, absence of LOS relaxation with swallowing and aperistalsis of the body of the oesophagus. The aetiology and pathogenesis of idiopathic achalasia is still controversial. METHODS AND RESULTS:We examined 16 oes...

journal_title：Histopathology

authors： Raymond L,Lach B,Shamji FM

更新日期：1999-11-01 00:00:00

abstract：:Extramural venous invasion (EMVI) is a well-known prognostic factor in colorectal cancer (CRC). Vascular invasion within the bowel wall, intramural vascular invasion (IMVI), has received less attention and its incidence and prognostic importance in CRC is not completely known. A systematic literature search was perfor...

journal_title：Histopathology

authors： Knijn N,van Exsel UEM,de Noo ME,Nagtegaal ID

更新日期：2018-04-01 00:00:00

abstract：AIMS:Congenital haemangiomas (CHs) can be subdivided into different subtypes [rapidly involuting CHs (RICHs), non-involuting CHs (NICHs), and partially involuting CHs (PICHs)]. During the first few days of life, RICHs may be associated with transient but sometimes marked thrombocytopenia. We sought to assess the histol...

journal_title：Histopathology

authors： El Zein S,Boccara O,Soupre V,Vieira AF,Bodemer C,Coulomb A,Wassef M,Fraitag S

更新日期：2020-08-01 00:00:00

abstract：AIMS:Rare gastric lesions composed of a combined proliferation of chief and oxyntic cells have been variably called adenocarcinoma of fundic gland type and oxyntic gland polyp/adenoma. Herein, we present a series of cases that show a morphological spectrum of chief and oxyntic cell proliferations. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Chan K,Brown IS,Kyle T,Lauwers GY,Kumarasinghe MP

更新日期：2016-05-01 00:00:00