Oval cells in hepatitis B virus-positive and hepatitis C virus-positive liver cirrhosis: histological and ultrastructural study.

abstract：AIMS:The aims of this study were to define whether diffuse cutaneous reticulohistiocytosis could be underpinned by somatic genetic alterations and represent a precursor of more aggressive forms of disease. METHODS AND RESULTS:A 59-year-old man with diffuse cutaneous reticulohistiocytosis experienced bone marrow locali...

journal_title：Histopathology

authors： Fusco N,Bonometti A,Augello C,Fabris S,Boiocchi L,Fiori S,Morotti D,Fracchiolla N,Berti E,Gianelli U

更新日期：2017-05-01 00:00:00

abstract：AIMS:Cluster of differentiation 103 (CD103), a marker of tissue resident memory T cells, is expressed on subsets of CD8+ T lymphocytes. We investigated the prognostic significance of CD103+ intra-epithelial tumour-infiltrating lymphocytes (iTILs) in invasive breast cancer (IBC). METHODS AND RESULTS:Immunohistochemistr...

journal_title：Histopathology

authors： Park MH,Kwon SY,Choi JE,Gong G,Bae YK

更新日期：2020-10-01 00:00:00

abstract：:We have studied the clinical, radiological and pathological features of three patients with recurrent massive lower gastrointestinal arterial haemorrhage. Case 1 was an example of Dieulafoy's vascular malformation within the proximal ascending colon in a 46-year-old woman. Cases 2 and 3 were men aged 81 and 83 years w...

journal_title：Histopathology

authors： Bateman AC,Beer TW,Bass PS,Odurny A,Gallagher PJ

更新日期：1996-09-01 00:00:00

abstract：AIMS:Immunohistochemistry plays a pivotal role in cancer differential diagnostics. To identify the primary tumour from a metastasis specimen remains a significant challenge, despite the availability of an increasing number of antibodies. The aim of the present study was to provide evidence-based data on the diagnostic ...

journal_title：Histopathology

authors： Gremel G,Bergman J,Djureinovic D,Edqvist PH,Maindad V,Bharambe BM,Khan WA,Navani S,Elebro J,Jirström K,Hellberg D,Uhlén M,Micke P,Pontén F

更新日期：2014-01-01 00:00:00

abstract：AIM:Achalasia is a disease of the oesophagus characterized by increased lower oesophageal sphincter (LOS) tone, absence of LOS relaxation with swallowing and aperistalsis of the body of the oesophagus. The aetiology and pathogenesis of idiopathic achalasia is still controversial. METHODS AND RESULTS:We examined 16 oes...

journal_title：Histopathology

authors： Raymond L,Lach B,Shamji FM

更新日期：1999-11-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:Hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome is caused by germline mutations in the Fumarate hydratase (FH) gene. In young women, the syndrome often presents with symptomatic uterine leiomyomas, leading to myomectomy or hysterectomy. In this study, we aimed to investigate the incidence and muta...

journal_title：Histopathology

authors： Liu C,Dillon J,Beavis AL,Liu Y,Lombardo K,Fader AN,Hung CF,Wu TC,Vang R,Garcia JE,Xing D

更新日期：2020-02-01 00:00:00

abstract：:An increased incidence of non-Hodgkin's lymphoma is seen in patients with immunodeficiency from any cause. The majority of these are high grade B-cell lymphoma and most are associated with the Epstein-Barr virus (EBV). In post-transplant lymphoma/lymphoproliferative disorders the tumour may regress following reduction...

journal_title：Histopathology

authors： Wotherspoon AC,Diss TC,Pan L,Singh N,Whelan J,Isaacson PG

更新日期：1996-02-01 00:00:00

abstract：:In the course of running two clinical trials between 1966 and 1985, data became available for 1315 patients, 713 in the first trial and 602 patients in the second trial, which has allowed comparison between histological findings in laryngeal and hypopharyngeal carcinoma, the observed survival and the tumour-free rates...

journal_title：Histopathology

authors： Wiernik G,Millard PR,Haybittle JL

更新日期：1991-11-01 00:00:00

abstract：AIMS:The clinical significance of common histological parameters in acute interstitial nephritis (AIN) is uncertain. We aimed to evaluate the utility of histology in predicting clinical outcomes in patients with AIN. METHODS AND RESULTS:Adult renal biopsies yielding a diagnosis of AIN between 2000 and 2015 were re-exa...

journal_title：Histopathology

authors： Rankin AJ,Cannon E,Gillis K,Crosby J,Mark PB,Geddes CC,Fox JG,Mackinnon B,McQuarrie EP,Kipgen D

更新日期：2020-04-01 00:00:00

abstract：AIMS:Previous studies have shown that increased vascularity is associated with tumour progression in human neuroblastoma (NB). The involvement of erythropoietin (Epo) in tumour angiogenesis has also been reported. The aim of this study was to correlate microvascular density and Epo/Epo-receptor (EpoR) expression in end...

journal_title：Histopathology

authors： Ribatti D,Poliani PL,Longo V,Mangieri D,Nico B,Vacca A

更新日期：2007-04-01 00:00:00

abstract：AIMS:To analyse the possible activation of distinct molecular pathways in mucosa-associated lymphoid tissue (MALT) lymphoma, we determined the prevalence of trisomies 3, 12, 18 in MALT lymphomas from different organs, as well as the prevalence of translocations of the MALT1 gene in a subset of primary breast MALT lymph...

journal_title：Histopathology

authors： João C,Farinha P,da Silva MG,Martins C,Crespo M,Cabeçadas J

更新日期：2007-01-01 00:00:00

abstract：:Cytokeratin antibodies have been widely used for the identification of trophoblast cells in the placental bed, following their invasion from the developing conceptus. Their identification centres upon the expression of cytokeratin in epithelial cells, from which trophoblast cells are derived. Our recent observations i...

journal_title：Histopathology

authors： Stiemer B,Graf R,Neudeck H,Hildebrandt R,Hopp H,Weitzel HK

更新日期：1995-11-01 00:00:00

abstract：AIMS:Merkel cell carcinoma represents poorly differentiated neuroendocrine carcinoma of cutaneous origin. In most studies, the vast majority of Merkel cell carcinomas are Merkel cell polyomavirus (MCPyV)-associated. SV40 polyomavirus immunohistochemistry is typically used in the diagnosis of other polyomavirus-associat...

journal_title：Histopathology

authors： Pelletier DJ,Czeczok TW,Bellizzi AM

更新日期：2018-07-01 00:00:00

abstract：AIMS:To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients. METHODS AND RESULTS:Immunostaining was analysed on a total of 192 biopsy samples of 22 Barrett's patients with no dysplasia...

journal_title：Histopathology

authors： van de Winkel A,van Zoest KP,van Dekken H,Moons LM,Kuipers EJ,van der Laan LJ

更新日期：2011-01-01 00:00:00

abstract：:A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

journal_title：Histopathology

authors： Huang DP,Ng HK,Ho YH,Chan KM

更新日期：1988-11-01 00:00:00

abstract：:This review intends to update current knowledge regarding molecular cytogenetics in melanocytic tumours with a focus on cutaneous melanocytic lesions. Advantages and limitations of diverse, already established methods, such as (fluorescence) in situ hybridization and mutation analysis, to detect these cytogenetic alte...

journal_title：Histopathology

authors： Blokx WA,van Dijk MC,Ruiter DJ

更新日期：2010-01-01 00:00:00

abstract：AIMS:The Notch signalling pathway is involved in normal development as well as tumorigenesis. However, it is unclear whether Notch activation is related to diverse clinicopathological factors in papillary thyroid carcinoma (PTC). METHODS AND RESULTS:We examined the relationship between clinicopathological factors and ...

journal_title：Histopathology

authors： Jung CW,Kong JS,Seol H,Park S,Koh JS,Lee SS,Kim MJ,Choi IJ,Myung JK

更新日期：2017-01-01 00:00:00

abstract：:The monoclonal antibody NCRC-11, which has epithelial membrane antigen (EMA)-like immunoreactivity, was used to identify intracytoplasmic lumina in a series of 105 adenocarcinomas from various sites and in 283 breast carcinomas; 55% of the non-breast carcinomas and all breast carcinomas except one of spindle cell type...

journal_title：Histopathology

authors： Quincey C,Raitt N,Bell J,Ellis IO

更新日期：1991-07-01 00:00:00

abstract：AIMS:Chondrosarcoma is primarily a tumour of adulthood and old age. Some studies indicate that survival is worse in paediatric than in adult chondrosarcomas. In view of the rarity of paediatric chondrosarcoma, few large studies are currently available. METHODS AND RESULTS:We evaluated the clinical, radiological and pa...

journal_title：Histopathology

authors： Gambarotti M,Righi A,Picci P,Bertoni F,Manfrini M,Donati DM,Dei Tos AP,Vanel D

更新日期：2016-06-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...

journal_title：Histopathology

authors： Farrell K,Jarrett RF

更新日期：2011-01-01 00:00:00

abstract：AIMS:Ectomesenchymal chondromyxoid tumour (ECT) is a rare, benign intraoral neoplasm showing a predilection for the anterior dorsum of the tongue. The World Health Organization includes ECT in the pathological spectrum of soft tissue myoepithelioma. EWS RNA-binding protein 1 gene (EWSR1) rearrangement is found in 45% o...

journal_title：Histopathology

authors： Argyris PP,Bilodeau EA,Yancoskie AE,Trochesset D,Pambuccian SE,Wetzel SL,Shah SS,Edelman M,Freedman P,Dolan M,Koutlas IG

更新日期：2016-10-01 00:00:00

abstract：:Six cases of polymorphous low-grade adenocarcinoma (terminal duct adenocarcinoma) of the minor salivary glands are presented. In all but one there was a history of a painless intra-oral mass of fairly long duration. The histopathological appearances were characterized by cytological uniformity in a variety of morpholo...

journal_title：Histopathology

authors： Simpson RH,Clarke TJ,Sarsfield PT,Gluckman PG,Babajews AV

更新日期：1991-08-01 00:00:00

abstract：:While the histological grade of a renal cell carcinoma is of prognostic significance there is poor concordance amongst pathologists in the use of these grading systems. Many grading systems have been described, but none has achieved widespread acceptance. The objective of this study was to assess the degree of interob...

journal_title：Histopathology

authors： Lanigan D,Conroy R,Barry-Walsh C,Loftus B,Royston D,Leader M

更新日期：1994-05-01 00:00:00

abstract：:Carcinosarcomas of the bladder are rare. We describe three such tumours, including an apparently unique case in which the components comprised liposarcoma and poorly-differentiated transitional cell elements. A second example included chondrosarcomatous elements. These two tumours showed architectural and immunocytoch...

journal_title：Histopathology

authors： Bloxham CA,Bennett MK,Robinson MC

更新日期：1990-01-01 00:00:00

abstract：AIMS:In this study, we aimed to investigate the clinicopathological features of CD4+ and/or CD56+ immature haematolymphoid malignancy (iHLM), including blastic plasmacytoid dendritic cell neoplasm (BPDCN). METHODS AND RESULTS:We analysed the clinicopathological features of 46 patients diagnosed consecutively with CD4+...

journal_title：Histopathology

authors： Suzuki Y,Kato S,Kohno K,Satou A,Eladl AE,Asano N,Kono M,Kato Y,Taniwaki M,Akiyama M,Nakamura S

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to document the patterns of cytoplasmic Ig heavy and light chain expression in reactive lymphoid tissue, using single and double immunoenzymatic labelling techniques. This investigation was undertaken, firstly, to provide information on whether the normal counterparts of high grade lymphoma c...

journal_title：Histopathology

authors： Morris HB,Mason DY,Stein H,Lennert K

更新日期：1983-11-01 00:00:00

abstract：AIMS:The purpose of this study was to examine the occurrence of CD44 isoforms in breast carcinomas and their role in predicting clinical outcome. METHODS AND RESULTS:Shock-frozen tumour tissues from 110 patients with breast carcinoma were examined by immunohistochemistry using antibodies directed against CD44s, v5, v6...

journal_title：Histopathology

authors： Berner HS,Suo Z,Risberg B,Villman K,Karlsson MG,Nesland JM

更新日期：2003-06-01 00:00:00

abstract：:The paper reports a re-evaluation--based on the Kiel classification for non-Hodgkin lymphomas--of a group of cases initially diagnosed as undifferentiated small cell carcinomas or primary lymphomas of the thyroid. Twelve such cases were found among the 155 cases of primary malignant tumours of the thyroid recorded at ...

journal_title：Histopathology

authors： Heimann R,Vannineuse A,De Sloover C,Dor P

更新日期：1978-05-01 00:00:00

abstract：AIMS:To compare the expression and prognostic value of the cell cycle markers Aurora kinase A (AURKA) and Ki67 in neuroblastoma, because AURKA expression levels have greater prognostic significance than those of Ki67 in some cancers. METHODS AND RESULTS:Eighty-eight neuroblastomas were immunostained with anti-AURKA an...

journal_title：Histopathology

authors： Ramani P,Nash R,Rogers CA

更新日期：2015-02-01 00:00:00